The Use of Deep Learning in Primary Agricultural Products Freshness Assessment: A Systematic Review.

Primary agricultural products are closely related to our daily lives, as they serve not only as raw materials for food processing but also as products directly purchased by consumers. These products face the issue of freshness decline and spoilage during both production and consumption. Freshness degradation induces sensory deterioration and nutritional loss and promotes harmful substance accumulation, causing gastrointestinal issues or even endangering life.

Effect of warm water soaking for raw rough rice on in vitro starch digestibility of cooked rice.

Background: The present study investigated the influence of mild heat treatment on harvested raw rough rice (Oryza sativa L. cv. Toyomeki) by warm water soaking at 65 °C with respect to the physicochemical properties and starch digestibility of cooked rice.

Expression of host-specific Lysyloxidase double-stranded RNA in Metarhizhium anisopliae enhanced virulence against the rice pest Sogatella furcifera.

Background: Entomopathogenic fungi show great potential as biological control agents for managing insect pests. However, host defenses have limited the effectiveness of these fungi in practice. Utilizing genetic engineering-based technology could be a promising strategy to enhance the killing efficiency of these fungi against insect pests.

The Impact of Adjuvant Drug Therapy on Overall Survival in Patients with Clear Cell Renal Cell Carcinoma: A Systematic Review and Meta-Analysis.

Purpose Clear cell renal cell carcinoma (ccRCC), the dominant subtype of renal malignancy, has a rising global incidence and mortality. While surgery is the standard of care for localized cases, adjuvant therapy aims to improve outcomes in high-risk postoperative patients. To quantify the clinical value of adjuvant pharmacotherapy, this systematic review and meta-analysis assesses its effect on overall survival (OS), disease-free survival (DFS), and progression-free survival (PFS) in patients with ccRCC.

Screening of Relevant Genes and Signalling Pathways Affecting Adult Urosepsis: A Bioinformatic Analysis.

Purpose: Urosepsis, a condition caused by a urinary tract infection spreading to the bloodstream, has a complex epigenetic behavior in its cellular and molecular pathophysiology. The objective of this study was to identify relevant genes and signaling pathways in adult urosepsis through a bioinformatic analysis of differentially expressed genes (DEGs).

Materials And Methods: In this in-silico study, the GSE69528 dataset, containing 138 total RNA blood samples from patients with sepsis and uninfected controls, was obtained from the Gene Expression Omnibus (GEO) database.

Preliminary Functional Outcome Following Robotic Intracorporeal Orthotopic Ileal Neobladder with Integrated Pelvic Fascial Structure-Sparing in Males with Bladder Cancer.

Purpose: To describe our integrated pelvic fascial structure-sparing (IPFSS) technique for robotic-assisted radical cystectomy (RARC) with intracorporeal orthotopic neobladder (ONB) reconstruction and to evaluate its impact on urinary continence and sexual function in male patients.

Methods: This retrospective observational study was conducted at a single high-volume center. Male bladder cancer patients who underwent IPFSS RARC with ONB were included.

A Quantitative Analysis of Kurtosis Impact on Occupational Complex Noise-Induced Hearing Loss.

Background: Workers in industry settings are often exposed to complex noise, which poses a greater risk to hearing loss than continuous noise at equivalent energy levels. Previous studies have identified kurtosis as an essential metric for evaluating complex noise-induced hearing loss (NIHL). This study aimed to characterize the distribution of workers exposed to complex noise, examine the associations between kurtosis and changes in hearing thresholds at various frequencies, and explore kurtosis's role in estimating NIHL and its integration into occupational hearing loss prevention programs.

Identification of a Pseudomonas brassicacearum strain as a potential biocontrol agent against clubroot in cruciferous plants through endophytic bacterial community analysis and culture-dependent isolation.

Background: Clubroot, caused by Plasmodiophora brassicae, significantly impacts cruciferous crop production worldwide. Biocontrol is an environmentally friendly and promising approach for clubroot management. Endophytic bacteria are known for their ability to promote plant growth and induce resistance against plant diseases.

Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer's Disease: A Prospective Study of 122 959 UK Biobank Participants.

The relationship between dietary biotin intake and cognitive function remains unclear. This study explores the association between biotin and dementia, and the mediating role of inflammation indicators. Dietary biotin intake was assessed via the 24-h recall questionnaire.

Dual-Mode Hybrid Discharge Plasma-Activated Injectable Hydrosol for Enhanced Immunotherapeutic Cancer Therapy.

Although cold atmospheric plasma is a promising therapeutic technique for tumor immunotherapy via reactive oxygen and nitrogen species (RONS), the challenges associated with the generation and delivery of these RONS hamper clinical adoption. Herein, a dual-mode hybrid discharge plasma-activated sodium alginate hydrosols (PAH) is proposed to enhance the antitumor immune response. Gaseous highly reactive RONS are generated by dual-mode hybrid plasma produced by mixed O and NO modes, which are converted into aqueous RONS in PAH via gas-liquid reactions between plasma and hydrosols.

Quantifying the Reduction of OER Overpotential on Magnetic Electrocatalysts Under Magnetic Fields.

Magnetic-field enhancement of the oxygen evolution reaction (OER) represents a promising route toward more efficient alkaline water electrolyzers, yet its origin remains debated due to overlapping effects of mass transport and reaction kinetics. Here, we present a general experimental strategy that employs strong forced convection to suppress uncontrolled transport arising from natural diffusion and magnetohydrodynamic (MHD) flows. Using polycrystalline Au electrodes, we show that this approach resolves subtle OER variations under controlled flow and field conditions.

Targeting O-GlcNAcylated METTL3 impedes MDS/AML progression via diminishing SRSF1 mA modification.

N6-methyladenosine (mA) modification, primarily regulated by methyltransferase-like protein 3 (METTL3), plays a pivotal role in RNA metabolism and leukemogenesis. However, the post-translational mechanisms governing METTL3 stability and function remain incompletely understood. Given the widespread occurrence of O-GlcNAcylation on nuclear and cytosolic proteins, we hypothesized that METTL3 might undergo O-GlcNAcylation, thereby influencing its stability and oncogenic function in myeloid malignancies.

Comprehensive sampling from mitochondrial genomes substantiates the Neoproterozoic origin of land plants.

Molecular phylogenetics illustrates the evolution and divergence of green plants by employing sequence data from various sources. Interestingly, phylogenetic reconstruction based on mitochondrial genes tends to exhibit incongruence with those derived from nuclear and chloroplast genes. Although the uniparental inheritance and conservatively retained protein-coding genes of mitochondrial genomes inherently exclude certain potential factors that affect phylogenetic reconstruction, such as hybridization and gene loss, the utilization of mitochondrial genomes for phylogeny and divergence time estimation remains limited.

Fine tuning wheat development for the winter to spring transition.

The coordination of floral developmental stages with the environment is important for reproductive success and the optimization of crop yields. The timing of different developmental stages contributes to final yield potential with optimal adaptation enabling development to proceed without being impacted by seasonal weather events, including frosts or end of season drought. Here we characterise the role of FLOWERING LOCUS T 3 (FT3) in hexaploid bread wheat (Triticum aestivum) during the early stages of floral development.

CDLR-net: a ECG classification network based on deep residual shrinkage networks and LSTM.

Many traditional classification networks directly use the limb two-lead signal (MLII) ECG signals as input for training. However, this method suffers from reduced accuracy when ECG features are not obvious, especially for premature heartbeats. To solve the issue, this paper proposed a novel network, namely CDLR-Net, that combines a Deep Residual Shrinkage Network (DRSN) with a Long Short-Term Memory (LSTM).

Prognostic role of the baseline neutrophil‒eosinophil ratio in cancer patients: a meta-analysis and systematic review.

Background: Inflammation impacts the prognosis of numerous types of tumors. Inflammatory indicators such as the neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and neutrophil-to-eosinophil ratio (NER) have emerged as potential prognostic markers and are closely correlated with the outcomes of cancer patients. However, the connection between NER and cancer prognosis remains incompletely understood.

Deciphering pancreatobiliary intraductal oncocytic papillary neoplasms: integrative analysis of histomorphologic patterns, immunophenotypic markers, and emerging molecular biomarkers.

Purpose: We reviewed recent advancements in the characterization of intraductal oncocytic papillary neoplasm (IOPN) of the pancreas, with a specific focus on developments in immunohistochemical markers, molecular pathology, and pathogenic mechanisms over the past ten years (2015-2024). Through comprehensive analysis of current literature, we aimed to elucidate the evolving understanding of IOPN's biological behavior and diagnostic features, while identifying potential areas for future research in this distinctive pancreatic neoplasm.

Methods: English-language articles on IOPN were searched from Pubmed from the first report of IOPN of the pancreas in 2015 to 2024.

Development and Validation of a Prediction Model for Acute Ischemic Stroke Based on a Novel Ultrasound-Based Carotid Plaque Scoring System and Clinical Factors.

Background: Acute ischemic stroke (AIS) is characterized by high incidence, sudden onset, and often poor prognosis. Carotid atherosclerosis plays a crucial role in its pathogenesis, and ultrasound imaging offers a non-invasive method for evaluating carotid plaque characteristics. This study aimed to develop and validate a prediction model for AIS risk based on a novel ultrasound-based carotid plaque scoring system combined with clinical risk factors.

Chrysin Attenuates Myocardial Cell Apoptosis in Mice.

Myocardial infarction (MI), induced by ischemia and hypoxia of the coronary arteries, presents as myocardial necrosis. Patients often experience intense, prolonged retrosternal pain that is unrelieved by rest or nitrate therapy and is frequently associated with high blood myocardial enzyme levels. Physical effort may exacerbate this anxiety, increasing the likelihood of life-threatening consequences such as arrhythmias, shock, or cardiac failure.

Label-free immunoassay based on chemiluminescence-functionalized magnetic mesoporous nanoparticles for rapid detection of neuron-specific enolase.

Lung cancer, as one of the cancers with the highest morbidity and mortality rates in the world, requires accurate detection of its vital serum marker, neuron-specific enolase (NSE), which is a key challenge for early detection of lung cancer. However, traditional chemiluminescence immunoassay (CLIA) methods rely on labeled antibodies (Abs) and suffer from complex operations and high costs. In this work, a label-free CLIA based on CL-functionalized mesoporous magnetic nanoparticles (CuFeO@mSiO-Cys-Luminol-Au NPs) is developed for the rapid and sensitive detection of NSE.

Association of anthropometric parameter with myopia in children and adolescents: A systematic review and meta-analysis.

Objective: To systematically evaluate the association between anthropometric parameter and myopia in children and adolescents.

Methods: PubMed, Web of Science, EBSCO, Embase, CNKI, CBM, WanFang Data, and VIP databases were searched from inception to June, 2025. We collected cross-sectional studies on the association between anthropometric parameter and myopia in children and adolescents aged 0-25 years, including body mass index (BMI) and weight-adjusted waist index (WWI).

Deciphering disease-specific glycosylation: unraveling diabetes subtypes through serum glycopattern.

Latent autoimmune diabetes in adults (LADA) is a slowly progressing form of diabetes that develops in adulthood, characterized by autoimmune destruction of pancreatic β-cells and subsequent insulin deficiency, akin to type 1 diabetes (T1D). Due to its shared genetic, immunological, and metabolic features with both T1D and type 2 diabetes (T2D), LADA is frequently misdiagnosed and inappropriately treated as T2D. To address this, we developed the A.

Highly sensitive detection and mechanism study of tetracycline in water by CuFeO/NiCo-LDH heterojunction electrochemical sensor.

A CuFeO/NiCo-LDH heterojunction electrochemical sensor (LDH: layered double hydroxide) was developed for the sensitive detection of tetracycline (TC). The sensor was constructed by integrating ZIF-67-derived nanocage NiCo-LDH on nickel foam with CuFeO, forming a p-n heterojunction that enhanced electron transfer and TC adsorption. The sensor exhibited bilinear detection ranges (0.