Dual-functional phthalamide modulation of aging-resistant PbI for efficient perovskite solar cells.

The sequential preparation of perovskite solar cells (PSCs) has received widespread concern for its use in large-scale perovskite modules and perovskite/silicon tandem solar cells. However, the instability of the PbI precursor solution and the incomplete reaction of ammonium salts hinder the industrialization of PSCs. Here, by introducing phthalamide (PA) into PbI solution, the carbonyl oxygen of PA molecules undergoes a bidentate coordination reaction with Pb to form an octahedral coordination structure, and the nitrogen atom in the -NH group exhibits weakly acidic properties due to the conjugation effect.

Understanding trait emotional intelligence and L2 willingness to communicate: The serial mediation of perceived teacher support and L2 emotions.

One of the primary goals of second language (L2) instruction is to enable students to actively engage in L2 communication, with willingness to communicate (WTC) serving as a critical antecedent that facilitates such communicative behavior. Therefore, research on L2 students' WTC (L2 WTC) is gaining sustained attention in recent years. A variety of personality (e.

Many plants naturalized as aliens abroad have also become more common within their native regions.

Due to anthropogenic pressure some species have declined whereas others have increased within their native ranges. Simultaneously, many species introduced by humans have established self-sustaining populations elsewhere (i.e.

Calix[]azanediyldibenzoate: Intramolecular Hydrogen Bond-Assisted Synthesis, Acidichromism, and Oriented Self-Assembly.

Here, intramolecular hydrogen bond (IMHBs)-induced rigidity is used for the first time to synthesize macrocyclic arenes. Calix[]azanediyldibenzoates (C[]A, where = 3, 4, or 5) are synthesized through a one-step condensation reaction between dimethyl 2,2'-azanediyldibenzoate and paraformaldehyde. Compared to the monomer, the macrocycles exhibit a fast and significant acidochromic response due to the intramolecular charge transfer that is boosted by the synergistic effect of their adsorption and protonation.

Deep Learning Based Multiomics Model for Risk Stratification of Postoperative Distant Metastasis in Colorectal Cancer.

Rationale And Objectives: To develop deep learning-based multiomics models for predicting postoperative distant metastasis (DM) and evaluating survival prognosis in colorectal cancer (CRC) patients.

Materials And Methods: This retrospective study included 521 CRC patients who underwent curative surgery at two centers. Preoperative CT and postoperative hematoxylin-eosin (HE) stained slides were collected.

Carboxymethyl chitosan-induced modification of the structure and regulation of the thermal aggregation of Pleurotus eryngii protein fractions to improve gel properties.

In recent years, interactions between polysaccharides and proteins have been widely considered for use to improve protein gel performances. We previously found carboxymethyl chitosan (CMCS) can increase Pleurotus eryngii protein (PEP) gel properties, but the contributions of different key PEP fractions to overall gel formation remain unclear. The aim of this study was to investigate how CMCS affects the gel properties of PEP via intermolecular interactions with PEP fractions, including PEP1-1, PEP2-2, and PEP5-1.

Light adaptive image enhancement for improving visual analysis in intercropping cultivation.

Intercropping maize and soybean with distinct plant heights is a typical practice in diversified cropping systems, where shadows cast by taller maize plants onto soybean rows pose significant challenges for image based recognition. This study conducted experiments throughout the entire soybean-maize intercropping period to address illumination variation. Based on the height difference between crops, solar elevation angle, and light intensity at the top of the soybean canopy, an illumination compensation regression model was developed.

Exploring the Nexus Between Ankle-Brachial Index and Atherosclerosis: A Bibliometric Analysis From 1989 to 2024.

Purpose: Cardiovascular and cerebrovascular diseases related to atherosclerosis represent a leading global health burden, contributing substantially to morbidity, disability, and premature mortality. The Ankle-Brachial Index (ABI) has emerged as a valuable non-invasive tool for screening peripheral artery disease and assessing the burden of systemic atherosclerosis. This bibliometric analysis aims to evaluate the research landscape, key contributors, and evolving trends in ABI and atherosclerosis studies.

Global, Regional, and National Burden of Lower Respiratory Infections in Children: A Systematic Analysis for the Global Burden of Disease Study, 2021.

Background: Lower respiratory infections (LRI) are a leading cause of death among children aged 0 to 14 globally. LRI burden estimates remain incomplete, especially in resource-limited settings.

Objective: To assess the global, regional, and national burden of LRI in children, analyse trends in incidence, mortality, and disability-adjusted life-years (DALYs), and predict future burden projections from 2022 to 2035, exploring variations in major bacterial pathogens.

Engineering Dual Active Sites of Au Nanoparticles and Nitrogen Vacancies for Enhanced Photocatalytic Toluene Selective Oxidation.

The efficient and selective activation of C(sp)-H bonds in toluene plays a pivotal role in the synthesis of value-added chemicals, yet achieving this transformation under mild conditions remains a challenge. Herein, the Au nanoparticles supported on rich-nitrogen vacancies on CN (AuNPs/CN-N) are synthesized via Ar atmosphere calcination and photoinduced deposition. The electronic state and coordination environment of Au species, as well as nitrogen vacancies, are systematically elucidated using X-ray absorption fine structure (XAFS), X-ray photoelectron spectroscopy (XPS), electron spin resonance (ESR), and in situ Fourier-transform infrared (in situ FT-IR).

Drought modifies the impacts of soil nutrient heterogeneity on native and alien plant growth in the absence of competition.

Soil nutrient heterogeneity has generally been shown to benefit alien plants more than native ones. However, whether drought, an important aspect of climate change, alters these effects remains an open question. We used a greenhouse experiment with two alien and two native herbaceous plants.

Selectively Modulating the Donor and Acceptor Aggregation Behaviors Through Solid Additive Isomerization Engineering for Organic Solar Cells Exceeding 20% Efficiency.

Regulating the film morphology is essential for achieving high-performance organic solar cells (OSCs). Given the distinct features of donor and acceptor materials, designing solid additives to selectively control the aggregation behaviors of them represents a key strategy for further development of OSCs. Herein, a series of bithiophene isomers solid additives (2,2-TT, 2,3-TT, and 3,3-TT) are designed for film morphology regulation.

Therapeutic strategies in traditional Chinese medicine for premature ovarian failure: Modulation of oxidative stress and autophagy-apoptosis via the AMPK/mTOR pathway.

Premature ovarian failure (POF), also referred to as premature ovarian insufficiency (POI), is a multifactorial reproductive endocrine disorder characterized by amenorrhea, infertility, hypoestrogenism, and elevated gonadotropin levels before the age of 40. Emerging evidence links its pathogenesis to oxidative stress and dysregulation of the autophagy-apoptosis balance in ovarian cells. Excessive accumulation of reactive oxygen species (ROS) impairs mitochondrial function in oocytes, while aberrant autophagy and granulosa cell apoptosis accelerate the depletion of primordial follicles.

Rapid-Onset Venous Thrombosis After Tibia Fracture: A Case Report.

BACKGROUND Conventional clinical understanding holds that venous thrombus formation typically occurs days after traumatic injury. However, our findings demonstrate that acute thrombosis can begin within 7.5 hours after fracture in knee trauma cases, challenging existing paradigms.

Unmasking MRSA's Armor: Molecular Mechanisms of Resistance and Pioneering Therapeutic Countermeasures.

Methicillin-resistant (MRSA), characterized by high-level β-lactam resistance and increasing multi-drug resistance, poses a severe and growing global threat to human health and public safety. This review examines MRSA's complex resistance mechanisms, including /-mediated expression of low-affinity PBP2a, regulatory roles of auxiliary genes like and , enzymatic inactivation by β-lactamases and modifying enzymes, efflux pump activity, and biofilm formation. We also systematically review novel therapeutic strategies, such as combination therapies, phage-derived biofilm disruptors, membrane-targeting silver nanoparticles, cell-penetrating antimicrobial peptides, colonization-competitive probiotics, and antibiotic-synergizing phytochemicals.

Preparation of rare earth metal hybridized magnetic chitosan nanoparticles for efficient DNA capture.

The advancement of biomedicine and molecular diagnostics depends on effective nucleic acid separation methods. Nevertheless, creating high-performing and environmentally friendly nucleic acid adsorbent materials is still challenging. In order to achieve high-quality DNA capture, this work creatively created a rare earth metal hybridized magnetic chitosan nanoparticle (FeO₄@CS@La(OH)₃) by combining the biocompatibility of chitosan with the effective coordination ability of La.

Regioselective C7 sulfinylation of 4-aminoindoles with sulfinates.

The regioselective C7-H sulfinylation of 4-aminoindoles was achieved by exploiting the -directing ability of the amino group. This transformation utilizes readily available sulfinates as versatile sulfinyl sources, allowing facile installation of structurally diverse sulfoxide motifs at the C7 position. In addition to aryl/alkyl sulfinates, trifluoromethyl sulfinate is also viable.

Tetrabutylammonium decatungstate-catalyzed hydroalkylation/alkoxylation of 3-methyleneisoindolin-1-ones with alcohols/ethers through hydrogen atom transfer process.

A highly efficient tetrabutylammonium decatungstate (TBADT)-catalyzed synthesis of isoindolinones using activated alkenes and alcohols/ethers hydrogen atom transfer process was developed. A variety of functionalized isoindolinones were obtained in good yields with high selectivity and broad functional group tolerance.

C-reactive protein-triglyceride glucose index and stroke risk in early cardiovascular-kidney-metabolic syndrome: a National cohort study.

Background: The C-reactive protein-triglyceride glucose index (CTI) has been associated with stroke risk in prior studies. However, its relevance among individuals with cardiovascular-kidney-metabolic (CKM) syndrome remains uncertain.

Methods: This study included 5767 participants with CKM syndrome stages 0-3 from the China Health and Retirement Longitudinal Study.

Saturated Alcohols Electrocatalytic Oxidations on Ni-Co Bimetal Oxide Featuring Balanced B- and L-Acidic Active Sites.

Investigating structural and hydroxyl group effects in electrooxidation of alcohols to value-added products by solid-acid electrocatalysts is essential for upgrading biomass alcohols. Herein, we report efficient electrocatalytic oxidations of saturated alcohols (C-C) to selectively form formate using NiCo hydroxide (NiCo-OH) derived NiCoO solid-acid electrocatalysts with balanced Lewis acid (LASs) and Brønsted acid sites (BASs). Thermal treatment transforms BASs-rich (89.

A novel MRI-based habitat analysis and deep learning for predicting perineural invasion in prostate cancer: a two-center study.

Background: To explore the efficacy of a deep learning (DL) model in predicting perineural invasion (PNI) in prostate cancer (PCa) by conducting multiparametric MRI (mpMRI)-based tumor heterogeneity analysis.

Methods: This retrospective study included 397 patients with PCa from two medical centers. The patients were divided into training, internal validation (in-vad), and independent external validation (ex-vad) cohorts (n = 173, 74, and 150, respectively).

Oxygenative Amidation of Metal Carbynoids via Pd-Catalyzed Three-Component Reaction of Alcohols, Imines, and α-Bromo Diazoacetates.

A palladium-catalyzed oxygenative amidation of metal carbynoids via three-component reaction of α-bromo diazoacetates, alcohols, and imines is reported. This strategy enables the simultaneous formation of C═O and C-N bonds at the carbynoid center, affording a broad range of oxindole-derived oxalamides in good to high yields under mild conditions. Mechanistic studies confirm that the carbonyl oxygen originates from the alcohol.

Preparation of Metal Core Piezoelectric Fiber Based on a Mold-Assisted Wet Process.

Metal core piezoelectric fiber (MPF) is gaining attention for their potential applications in smart wearables and fault detection due to their excellent dynamic responsiveness. Traditional manufacturing methods, however, are hindered by inefficiencies, environmental concerns, and inconsistent quality, limiting the large-scale production and application. This research presents a novel continuous fabrication method for MPF using enamel-coated wire molds.

Discovery of Phosphorylated Peptidomimetics Targeting Cbl-b SH2 Domain as Orthosteric Cbl-b Inhibitors by an Optimized Fluorescence Polarization Competition Assay.

Casitas B-lineage lymphoma-b (Cbl-b), a pivotal negative regulator of TCR signaling, is highly expressed in immune cells. Its inhibition potentiates immune-mediated antitumor effects. Herein, we constructed a potent fluorescent tracer, , based on the Cbl-b peptide inhibitor Utilizing this tracer, we established a fluorescence polarization (FP) assay with enhanced sensitivity, discriminative capacity, and precision for the activity evaluation and high-throughput screening of orthosteric Cbl-b Src homology 2 (SH2) domain inhibitors.

Carnosol attenuates Ang II-induced renal injury by p62-KEAP1-NRF2 signaling pathway.

Hypertension engenders numerous complications, including hypertensive renal disease (HRD). Recent studies have underscored the significance of redox homeostasis in hypertension-associated kidney disorders. Carnosol (Car) has been identified as a potent antioxidant in other diseases.