Bombyx mori UFBP1 regulates apoptosis and promotes BmNPV proliferation by affecting the expression of ER chaperone BmBIP.

Ubiquitin-fold modifier 1 (UFM1) is attached to protein substrates through the sequential activity of an E1 (UBA5) - E2 (UFC1) - E3 (UFL1) cascade. UFBP1 is a conserved UFL1-interacting protein in mammals. However, to date, no study has been conducted on UFBP1 in silkworm.

A rapid dual-mode SERS/FL cytosensor assisted via DNA Walker-based plasmonic nanostructures.

Various surface-enhanced Raman scattering (SERS) biosensors offer powerful tools for the ultrasensitive detection of circulating tumor cells (CTCs) and tumor diagnosis. Despite their efficacy, the swift and precise preparation of SERS plasmonic nanostructures poses an ongoing challenge. In this study, we introduce DNA-assisted plasmonic nanostructures capable of producing dual signals and facilitating DNA Walker signal amplification, resulting in the development of a SERS/Fluorescent (FL) dual-mode cytosensor for CTCs detection.

Optimizing chlorine dioxide treatment for enhanced post-harvest storage quality of .

This study investigated the impact of chlorine dioxide (ClO) treatment on the storage quality of after harvesting. samples treated with different concentrations (0.2, 0.

Quantitative physics-physiology relationship modeling of human emotional response to Shu music.

Music perception is one of the most complex human neurophysiological phenomena invoked by sensory stimuli, which infers an internal representation of the structured events present in a piece of music and then forms long-term echoic memory for the music. An intrinsic relationship between the basic acoustic property (physics) of music and human emotional response (physiology) to the music is suggested, which can be statistically modeled and explained by using a novel notion termed as quantitative physics-physiology relationship (QPPR). Here, we systematically analyzed the complex response profile of people to traditional/ancient music in the Shu area, a geographical concept located in the Southwest China and one of three major origins of the Chinese nation.

Covalent inhibitors meet epigenetics: New opportunities.

Epigenetic intervention has become an important therapeutic strategy for a variety of diseases, such as cancer. Although a small number of epigenetic drugs have been marketed, most of these inhibitors are limited by their poor efficacy, dose-dependent toxicity, poor selectivity, and drug resistance. The development of covalent inhibitors has progressed from questioning to resurgence.

Methamphetamine abuse impairs sequential working memory.

The ability to maintain and manipulate sequential information in working memory, referred to as sequential working memory, plays a vital role in our daily life. While research has shown that methamphetamine abuse affects the neural substrates and the overall functioning of working memory, its specific impact on sequential working memory remains unclear. In this study, we asked 62 abstinent methamphetamine-dependent participants and 59 control participants to complete a digit ordering task in which they saw four digits one-by-one over time and subsequently rearranged them in ascending order.

Deficient salience and default mode functional integration in high worry-proneness subject: a connectome-wide association study.

Worry has been conceptualized as a relatively uncontrollable chain of thought that increases the risk of mental problems, such as anxiety disorders. Here, we examined the link between individual variation in the functional connectome and worry proneness, which remains unclear. A total of 32 high worry-proneness (HWP) subjects and 25 low worry-proneness (LWP) subjects were recruited.

Exploring the role and mechanisms of environmental serious games in promoting pro-environmental decision-making: a focused literature review and future research agenda.

Environmental serious games aim to heighten players' awareness and comprehension of environmental issues, thus fostering pro-environmental decision-making. Research to date has affirmed these games' effectiveness in enhancing environmental knowledge and abilities, elevating consciousness regarding environmental matters, and promoting pro-environmental behavioral intentions and actions. Nonetheless, a detailed exploration into the precise mechanisms facilitating these impacts remains scarce.

Defect Passivation of Mn-Doped CsPbX(X=Cl,Br) Perovskite Nanocrystals as Electrocatalyst for Overall Water Splitting.

Mn doping has been used to improve the physical chemistry of lead halide perovskite nanocrystals such as CsPbX, where X is a halogen ion. In this paper, a two-phase method for Mn-doped CsPbX nanosheets (where X=Br, Cl), namely water-hexane system, is reported. Compared to conventional catalyst arrays, the band gap of CsPbBr nanocrystalline is easily tuned, the carrier diffusion distance is remote, the band edge position of the band structure is favorable for a wide range of electrocatalytic redox reactions, and the catalytic active site is maximally exposed, providing a larger electrolyte contact area.

Insights into the Flavor Profile of Yak Jerky from Different Muscles Based on Electronic Nose, Electronic Tongue, Gas Chromatography-Mass Spectrometry and Gas Chromatography-Ion Mobility Spectrometry.

It is well known that different muscles of yak exhibit distinctive characteristics, such as muscle fibers and metabolomic profiles. We hypothesized that different muscles could alter the flavor profile of yak jerky. Therefore, the objective of this study was to investigate the differences in flavor profiles of yak jerky produced by (LT), (TB) and (BF) through electronic nose (E-nose), electronic tongue (E-tongue), gas chromatography-mass spectrometry (GC-MS) and gas chromatography-ion mobility spectrometry (GC-IMS).

Based on the improved fuzzy analytic hierarchy and the TSE-MLR model energy consumption prediction of university: A case study.

The accurate prediction of building energy consumption on university campuses is a significant research area. Current studies often focus on predicting the energy consumption of specific building areas or individual equipment, and typically consider only one factor, limiting the accuracy and applicability of the predictions. This study introduces the Time Segmented Energy-Multiple Linear Regression (TSE-MLR) prediction model, which integrates the improved fuzzy analytic hierarchy and the multiple linear regression algorithm.

Triple Electron Attachments with a New Intermediate-Hamiltonian Fock-Space Coupled-Cluster Method.

The implementation of a new intermediate-Hamiltonian Fock-space coupled-cluster (IHFSCC) scheme for the (3,0) sector of the Fock space is reported. In this IHFSCC approach, the three-body contributions in the cluster operator corresponding to the (3,0) sector of the Fock space are considered, while and at the (1,0) and (2,0) level only include one- and two-body operators. By introducing a suitable partition of the wave operator, the intermediate Hamiltonian, which only depends on the two-body operator of S, is obtained.

The impact of environmental protection tax on the health of middle-aged and older adults: evidence from CHARLS data in China.

Introduction: With the aging population, the relationship between human health and the ecological environment has gained increasing attention. In China, it is imperative to evaluate the policy effects of the Environmental Protection Tax (EPT) on improving the ecological environment and enhancing the health of middle-aged and older adult people.

Methods: This study, based on data from the China Health and Retirement Longitudinal Study (CHARLS), employs a Difference-in-Differences (DID) model to assess the health effects of the EPT policy.

Gas-Sensing Performance of Metal Oxide Heterojunction Materials for SF Decomposition Gases: A DFT Study.

The online monitoring of GIS equipment can be realized through detecting SF decomposition gasses. Metal oxide heterojunctions are widely used as gas-sensing materials. In this study, the structural and electrical properties of InO-ZnO and TiO-ZnO heterojunctions were analyzed based on density functional theory calculations.

In Vitro and In Vivo Evaluation of Toxicity of Structurally Different Diamond-Like Carbon Wear Debris in Joint Replacements.

Diamond-like carbon (DLC) wear debris, which is often composed of different types of structures, is generated from DLC-modified artificial joints in the human body, and its biocompatibility evaluation is especially important to prevent wear-debris-induced implant failure. Here, RAW 264.7 macrophages (inflammatory-reaction assay) and primary mouse osteoblasts (osteoblastogenesis assay) were employed to investigate the toxicity of DLC wear particles (DWPs) by evaluation of cell viability and morphology, enzyme-linked immunosorbent assays, and quantitative reverse-transcription polymerase chain reaction (PCR).

A Congruent-Melt Infrared Nonlinear Optical Crystal NaSrAsS.

A quaternary metal thioarsenate infrared (IR) nonlinear optical (NLO) compound NaSrAsS was successfully prepared by a high-temperature reaction method from stoichiometric agents. It crystallizes in the tetragonal 42 with the unit cell parameters = 10.0393(3) Å, = 6.

Potassium and zinc improves physiological performance, nutrient use efficiency, and productivity of wheat.

Despite the critical role of balanced nutrition in crop productivity, the use of potash (K) and zinc (Zn) is not much practiced by Pakistani farmers. The reduced nutrient uptake and crop productivity together increase the costs associated with fertilization and revisit farmers' confidence in the efficacy and profitability of fertilizers. To address this problem, a field study was conducted in the research area of the MNS-University of Agriculture, Multan, in collaboration with Engro Fertilizers Limited.

Recent Progress in Free Radical Transformations of Allenamides.

Allenamides are special allenes, and the unique reactivity, selectivity (both stereoselective and regionally selective) and stability of allenamides have been widely studied. In this review, the development of the free radical transformation of allenamides over the last few years will be summarized. This review discusses in detail in three parts: intermolecular radical addition to C- X (X = N, S, O, Se) bonds, metal salt mediated cyclization of allenamides, and photocatalytic cyclization of allenamides.

How do income inequality, poverty and industry 4.0 affect environmental pollution in South Asia: New insights from quantile regression.

While many factors have been studied as potential causes of environmental degradation, the impact of poverty and inequality has been largely overlooked in the research. The Sustainable Development Goals are aligned with the intersection of poverty, inequality, and the environment. In addition, most previous research has used carbon dioxide (CO) emissions as a surrogate for pollution.

Gender bias in child custody judgments: Evidence from Chinese family court.

Based on a quantitative analysis of a novel dataset comprising 10,093 publicly available judgments of adjudicated child custody disputes from the China Judgments Online website, this article identifies potential gender bias in Chinese family courts under certain conditions. Key findings include: 1. Mothers are generally more proactive in seeking custody and are awarded custody in the majority of cases compared to fathers.

Adaptable Hybrid Beamforming with Subset Optimization Algorithm for Multi-User Massive MIMO Systems.

The exploiting of hybrid beamforming (HBF) in massive multiple-input multiple-output (MIMO) systems can enhance the system's sum rate while reducing power consumption and hardware costs. However, designing an effective hybrid beamformer is challenging, and interference between multiple users can negatively impact system performance. In this paper, we develop a scheme called Subset Optimization Algorithm-Hybrid Beamforming (SOA-HBF) that is based on the subset optimization algorithm (SOA), which effectively reduces inter-user interference by dividing the users set into subsets while optimizing the hybrid beamformer to maximize system capacity.