Multiparametric MRI-Based Intratumoral and Peritumoral Radiomics for Distinguishing Solitary Intrahepatic Mass-Forming Cholangiocarcinoma From Colorectal Liver Metastases.

Objective: To establish a model based on intratumoral and peritumoral radiomics for preoperatively differentiating solitary intrahepatic mass-forming cholangiocarcinoma (IMCC) lesions from colorectal cancer liver metastases (CRLM).

Methods: Preoperative MRI scans from IMCC patients were retrospectively obtained from three academic medical centers. Radiomics features were extracted from the intratumoral and multiple peritumoral regions.

How parental mediation affects adolescents' problematic smartphone use: the chain mediating role of basic psychological needs and positive outcome expectations.

Purpose: Problematic smartphone use can significantly jeopardize adolescents' academic development as well as their physical and mental health. Although previous studies have explored the role of parental mediation strategies in adolescents' problematic smartphone use, the underlying mechanisms remain unclear. This study aims to investigate the relationship between parental mediation and adolescents' problematic smartphone use, with a specific focus on the chain mediation effects of basic psychological needs and positive outcome expectations.

Identification of syrup adulteration in wolfberry honey using CNN-CBAM-SVM combined with H NMR.

To identify syrup adulteration in honey, a deep learning model based on the CNN-CBAM-SVM architecture combined with H NMR spectra was developed. The traditional CNN model was enhanced by incorporating the CBAM module and replacing the fully connected layer with an SVM classifier, making it well-suited for small sample sizes. The H NMR spectra of 20 genuine and 20 adulterated samples with two distinct syrups were divided into a training set (32 samples) and a validation set (8 samples).

Brightening self-trapped exciton emission in 2D metal-organic chalcogenolates via argentophilicity-mediated anisotropic compression.

An emerging class of two-dimensional semiconductor materials, metal-organic chalcogenolates (MOCs), have garnered significant attention due to the strong excitonic effects arising from their intrinsic soft, hybrid multiquantum-well structures. However, modifying excitonic transitions that strongly couple to the argentophilic networks and constructing their structure-property relationships in MOCs remain daunting challenges. Here, we use silver phenylselenolate (AgSePh) as a model system to manipulate excitonic behavior and uncover the fundamental photophysical mechanisms through pressure engineering.

Laser-modulated MnBiTe terahertz biosensor for high-sensitivity marine bacterial detection.

The prompt and precise identification of marine bacteria is essential for assessing ecosystem health and mitigating microbial contamination in aquatic environments. In this study, we introduce a terahertz (THz) biosensor that utilizes magneto-topological MnBiTe thin films, capitalizing on their quantum anomalous Hall effect and surface-dominated optoelectronic characteristics for label-free bacterial detection. Through the application of surface engineering and laser modulation techniques, the sensor achieves a detection limit of 9.

High-pressure-induced phase transition in 2-amino-6-nitrobenzothiazole.

In situ high-pressure synchrotron angular dispersive x-ray diffraction (ADXRD) experiments reveal a pressure-induced structural phase transition in the molecular crystal of 2-amino-6-nitrobenzothiazole (C7H5N3O2S, 2A6NBT) at ∼2.0 GPa. Furthermore, in situ high-pressure Fourier transform-infrared absorption and Raman spectroscopy experiments confirm the occurrence of this phase transition and clarify the structural evolution.

Research progress on microbial pesticides.

With the growing restrictions on chemical pesticides, microbial pesticides have emerged as the predominant biopesticides due to their notable advantages, such as high efficacy, broad-spectrum activity, safety, and environmental compatibility, highlighting their substantial potential for application. This paper systematically describes the properties of microbial pesticides of bacterial, fungal, viral and genetically engineered microbial origin and provides insights into the mechanism of action of these pesticides and their application in agricultural production. Furthermore, we summarize recent advancements in microbial pesticide research and anticipate future developments, serving as a reference for further investigation and application.

Potential candidate genes influencing meat production phenotypic traits in sheep: a review.

This review examines the genetic basis of meat production phenotypic traits in sheep, addressing the challenge of enhancing carcass and meat quality to meet global demand. The article identifies key potential genes associated with vertebral traits, body size, muscle development, and fat deposition across diverse sheep breeds worldwide. Through comprehensive analysis of recent literature (2018-2025), the study synthesizes findings from genome-wide association studies, candidate gene approaches, and transcriptomic analyses.

Piezoelectrically Enhanced Charge Carriers Transfer in a Highly Conjugated Nickel(II)-Acetylide Framework for Photocatalytic CO Reduction.

The piezoelectric field within two-dimensional (2D) piezo-photocatalysts offers a promising strategy for enhancing charge carrier kinetics to convert CO into valuable chemicals. However, the diversity of available 2D piezo-photocatalysts remains limited. Here, we present a highly conjugated Ni-acetylide framework (HETP-Ni-GY) featuring triangular atomic pores arranged in a hexagonal symmetry, constructed by incorporating Ni-complex into the graphdiyne (GDY) framework Ni-bis(acetylide) linkages (-C≡C-Ni(PEt)-C≡C-).

Theoretical Analysis and Research on Support Reconstruction Control of Magnetic Bearing with Redundant Structure.

At present, the redundant structures are one of the most effective methods for solving magnetic levitation bearing coil failure. Coil failure causes residual effective magnetic poles to form different support structures and even asymmetrical structures. For the magnetic bearing with redundant structures, how to construct the electromagnetic force (EMF) that occurs under different support structures to achieve support reconstruction is the key to realizing fault tolerance control.

Discovery of 4,5,6,7-Tetrahydrothieno [3,2-b] Pyridine as Novel Fungicide Lead Scaffold.

To identify fungicide lead compounds with novel scaffold and high efficacy, a library of 4,5-dihydrotetrazolo [1,5-a]thieno [2,3-e]pyridine derivatives, consisting of 10 newly synthesized compounds and 12 previously reported compounds, was evaluated for their potential as fungicide agents. In vitro bioassay results indicated that some target compounds exhibited certain antifungal activity against the tested fungi at a concentration of 50 μg/mL. Especially, compounds , , , and demonstrated promising antifungal activity against , , and , with EC values ranging from 4.

An Ultra-Precision Smoothing Polishing Model for Optical Surface Fabrication with Morphology Gradient Awareness.

To improve the surface morphology quality of ultra-precision optical components, particularly in the suppression of mid-spatial frequency (MSF) errors, this paper proposes a morphology gradient-aware spatiotemporal coupled smoothing model based on convolutional material removal. By introducing the Laplacian curvature into the surface evolution framework, a curvature-sensitive "peak-priority" mechanism is established to dynamically guide the local dwell time. A nonlinear spatiotemporal coupling equation is constructed, in which the dwell time is adaptively modulated by surface gradient magnitude, local curvature, and periodic fluctuation terms.

Berberis aristata fruit extract, nanocellulose, and biopolymers-infused bionanocomposite film: a green and sustainable alternative to plastics for food preservation and monitoring.

A chitosan/polyvinyl alcohol/starch (CS/PVA/S) bionanocomposite film was fabricated through solution casting for smart food packaging by incorporating Berberis aristata (Chutro; CH) fruit extract and corncob-derived nanocellulose (NC) fibrils. The CS/PVA/S/CH/NC film exhibited pH-responsive intelligent behavior and strong UV barrier properties (up to 400 nm) compared to the negligible UV barrier and intelligent properties of CS/PVA/S film. The hydrophobicity (WCA for CS/PVA/S was 60.

Characterization of Physicochemical Quality and Volatiles in Donkey Meat Hotpot Under Different Boiling Periods.

Hotpot dishes are widely favored by consumers for their flavor profiles developed during the cooking process. This study investigated the quality characteristics and volatile compounds (VOCs) of donkey meat slices across varying boiling durations (0-42 s) using gas chromatography-ion mobility spectrometry (GC-IMS). The results demonstrated that donkey meat boiled for 12-18 s exhibited optimal characteristics in terms of meat retention, color parameters, shear force values, and pH measurements.

Do College Freshmen Who Engage More in Online Social Comparison Tend to Be More Confused About Themselves? The Roles of Rumination and Self-Compassion.

Online social comparisons play a vital role in adolescents and young adults' self-development. This study extended research on the influence of online social comparisons on self-concept clarity among college freshmen. This study investigated the mediating role of rumination in the relationship between online social comparisons and self-concept clarity among college freshmen and further examined the moderating effect of self-compassion on this mediational pathway.

The Role of TGF-β Signaling Pathway in Determining Small Ruminant Litter Size.

The transforming growth factor-beta (TGF-β) superfamily plays a crucial role in regulating female reproductive traits, particularly litter size, in small ruminants, such as sheep and goats. This review comprehensively examines the molecular mechanisms through which TGF-β superfamily members-including bone morphogenetic proteins (), growth differentiation factor 9 (), inhibin ( and ), and associated signaling genes-influence ovarian follicular development, ovulation rate, and ultimately, litter size. We synthesize recent findings on polymorphisms in key genes, such as , , and family genes, across diverse sheep and goat breeds worldwide.

Non-Bovine Milk as Functional Foods with Focus on Their Antioxidant and Anti-Inflammatory Bioactivities.

The growing interest in functional foods has directed scientific attention toward alternative milk sources, particularly camel and donkey milk, which have been traditionally consumed for their purported health benefits across diverse cultures. These milk sources possess unique nutritional profiles and bioactive compositions that differ substantially from conventional bovine milk. This review examines the current scientific understanding of the anti-inflammatory and antioxidant bioactivities of camel and donkey milk, exploring their bioactive constituents and therapeutic potential.

Exploring the effects of the anti-diarrheal formula on intestinal oxidative stress based on network pharmacology, molecular docking, and microbiomics.

The anti-diarrheal formula, a traditional Chinese remedy made from Punica granatum peel, Agrimonia eupatoria, and Gynostemma Blume, contains compounds that reduce oxidative stress. In our previous study, it was shown that the Anti-diarrheal Formula has a therapeutic effect on dysentery in livestock, so follow-up experiments are needed to test the mechanism of action.This study examines the formula's pharmacological mechanisms in treating dysentery through microbiome analysis and network pharmacology to clarify its effects on oxidative stress.

GSAformer: Group sparse attention transformer for functional brain network analysis.

Functional brain network (FBN) analysis based on fMRI has proven effective for neurological/mental disorder classification. Traditional methods usually separate the FBN construction from the subsequent classification tasks, resulting in a suboptimal solution. Recently, transformers, known for their attention mechanisms, have shown strong performance in various tasks, including brain disorder classification.

Synergistic regulation of fluorescence thermometer sensitivity based on LSPR effect and energy transfer.

Fluorescence intensity ratio (FIR) thermometry is an ideal non-contact temperature measurement method with rapid response and high sensitivity. Improving sensitivity and stability is always the research hotspot in this field. Energy transfer between the emission centers plays a key role to improve temperature sensitivity.

Enhanced stability and anticancer activity of (-)-epicatechin gallate and procyanidin B2: Synergistic effects of natural deep eutectic solvent-based ovalbumin glycation and non-covalent complexation.

In this study, glycated ovalbumin (GOVA) with a high degree of grafting (90.2 %) was prepared via response surface methodology (RSM) in natural deep eutectic solvents (NADES). The interactions between GOVA and (-)-epicatechin gallate (ECG) or procyanidin B2 (PB2) were compared using fluorescence spectroscopy and molecular docking.

A novel AuPt@CeVO bifunctional nanozyme with strong cascade SOD/POD-like catalytic activity enhances microfluidic photoelectrochemical signal amplification for ultrasensitive neuron-specific enolase detection.

A newly designed and highly effective cascade difunctional nanozyme, AuPt@CeVO, has been developed to function as a microfluidic photoelectrochemical (PEC) signal label, enabling the highly sensitive identification of bioproteins. This study utilized Z-scheme CuI/BiOI photoactive nanocomposites by applying CuI onto the BiOI nanoarray's surface, which serves as a sensor matrix to obtain an improved and stable photocurrent. The nanoarray arrangement in BiOI greatly improves the consistency and durability of the sensing platform.

A multi-source data-driven framework for probabilistic flood risk assessment using cascade machine learning models: case study in the Sichuan Basin.

Along with global climate change, more frequent extreme climate phenomena have led to an increasing number of and increasingly severe flood disasters. Extreme rainfall events are capable of generating substantial amounts of surface runoff. Concurrently, the progression of urbanization has given rise to the expansion of impervious surfaces, thereby augmenting the likelihood of flood disasters.

Pressure-modulated intermolecular charge transfer in a cocrystal to achieve tunable luminescence.

Cocrystal engineering offers the opportunity to achieve noncovalent synthesis of functional molecules with tunable luminescent features. In this study, Pe-4F2CN co-crystal was fabricated by using perylene (Pe) and tetrafluoroterephthalonitrile (4F2CN) through charge-transfer (CT)-induced assembly. The co-crystal exhibits two distinct emission bands and pronounced piezochromic properties, achieving the tunable luminescence from yellow to red upon compression.

Surface-Passivation-Enabled Electronic and Optical Property Engineering in Two-Dimensional GaSb.

Gallium antimonide (GaSb) is promising for next-generation electronics and optoelectronics due to its high carrier mobility and narrow bandgap (∼0.725 eV). However, in two-dimensional (2D) form, surface dangling bonds cause instability and Fermi-level pinning, degrading performance.