Factors influencing HPV vaccination willingness among male college students in Jinan according to the health belief model.

Human papillomavirus (HPV) infection is a significant global public health threat. HPV vaccination in males is crucial for reducing the risk of related cancers and partner infection. On the basis of the health belief model (HBM), this study delves into the factors influencing the willingness to receive HPV vaccination among male college students in Jinan.

The Fabrication of Porous AlO Ceramics with Ultra-High Mechanical Strength and Oil Conductivity via Reaction Bonding and the Addition of Pore-Forming Agents.

Reaction bonding (RB) using Al powder is an effective method for preparing porous ceramics with low shrinkage, high porosity, and high strength. However, it remains challenging to optimize mechanical strength and oil conductivity simultaneously for atomizer applications. Herein, aiming at addressing this issue, porous AlO ceramics with ultra-high mechanical strength and oil conductivity were fabricated via the RB process using polymethyl methacrylate (PMMA) microspheres as the pore-forming agent.

Synergistic regulation of fluorescence thermometer sensitivity based on LSPR effect and energy transfer.

Fluorescence intensity ratio (FIR) thermometry is an ideal non-contact temperature measurement method with rapid response and high sensitivity. Improving sensitivity and stability is always the research hotspot in this field. Energy transfer between the emission centers plays a key role to improve temperature sensitivity.

A radiomics-clinical predictive model for difficult laparoscopic cholecystectomy based on preoperative CT imaging: a retrospective single center study.

Background: Accurately identifying difficult laparoscopic cholecystectomy (DLC) preoperatively remains a clinical challenge. Previous studies utilizing clinical variables or morphological imaging markers have demonstrated suboptimal predictive performance. This study aims to develop an optimal radiomics-clinical model by integrating preoperative CT-based radiomics features with clinical characteristics.

Effectiveness and safety of sirolimus in the treatment of venous malformations: A meta-analysis of prospective studies.

Background: Venous malformations are prevalent vascular anomalies. Recent clinical studies have explored the use of sirolimus for these conditions, particularly in patients who are not candidates for, or have shown limited response to, traditional treatments such as sclerotherapy and surgery. This meta-analysis systematically evaluates the efficacy and safety of sirolimus in treating venous malformations.

Structural characterisation of hawthorn polysaccharide and its mechanisms of action against non-alcoholic fatty liver disease.

Non-alcoholic fatty liver disease (NAFLD) represents a significant health risk to humans; however, effective pharmacological treatments are currently unavailable. Hawthorn polysaccharide (HP) possesses a range of beneficial properties that enhance cardiovascular health, diabetes management, antiviral activity, and antioxidant function. However, further investigations are required to clarify the anti-NAFLD effects of HP and elucidate the underlying mechanisms.

Recent Developments and Applications of Surface-Enhanced Raman Scattering Spectroscopy in Pesticides Detection: From Single Pesticides to Mixed Pesticides.

Pesticides directly pollute the environment and food, eventually being absorbed into the human body. Their residues are highly toxic and pose serious health risks. Chromatography and gas liquid chromatography tandem mass spectrometry are widely employed for pesticide residue detection.

Dual Stream Feature Fusion 3D Network for supraspinatus tendon tear classification.

The classification of medical images is of significant importance for computer-aided diagnosis. Supraspinatus tendon tear is a common clinical condition. Classifying the severity of supraspinatus tendon tears accurately aids in the selection of surgical techniques and postoperative rehabilitation.

From Frequency to Temporal: Three Simple Steps Achieve Lightweight High-Performance Motor Imagery Decoding.

Objective: To address the challenges of high data noise and substantial model computational complexity in Electroencephalography (EEG)-based motor imagery decoding, this study aims to develop a decoding method with both high accuracy and low computational cost.

Methods: First, frequency domain analysis was performed to reveal the frequency modeling patterns of deep learning models. Utilizing prior knowledge from brain science regarding the key frequency bands for motor imagery, we adjusted the convolution kernels and pooling sizes of EEGNet to focus on effective frequency bands.

Global burden of maternal hypertensive disorders (1990-2045): trends, regional disparities, and causal links to occupational exposures.

Background: Maternal Hypertensive Disorders (MHD), encompassing gestational hypertension, chronic hypertension, preeclampsia, and eclampsia, which was a significant contributor to maternal morbidity and mortality, particularly in regions with lower socioeconomic status.

Methods: Using data from the 2021 Global Burden of Disease (GBD) study, we analyzed the burden of MHD globally. We used the slope index and concentration index to measure cross-country inequality in MHD burden, and employed a Bayesian age-period-cohort (BAPC) model to project the burden from 2022 to 2045.

Elucidation of the anti-arthritic mechanism of Guizhi-Shaoyao-Zhimu decoction by reshaping circadian rhythm.

Rheumatoid Arthritis (RA) exhibits pronounced circadian oscillations, with variations in joint stiffness, pain, and swelling following rhythmic patterns. Our preliminary research suggests that inflammatory cytokines in RA serum display rhythmicity closely associated with circadian rhythms. Additionally, circadian clock genes show a tendency towards disordered expression in RA, suggesting potential new therapeutic avenues from a circadian perspective.

One-Stage Procedure Using Free Internal Oblique Muscle of the Abdomen Flap for Longstanding Facial Paralysis: Experience With 13 Patients.

Background: The transplantation of a free muscle flap represents a trusted method for restoring function and movement in paralyzed facial muscles. However, the choice of donor site is still controversial and can lead to many problems. Discovering appropriate muscle flap sources can effectively mitigate these problems, offering a wider array of options and novel approaches for treating facial paralysis.

Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.

The present study aimed to explore the underlying antitumor effects of bavachin on laryngopharyngeal cancer and . Tu212 and FaDu cells were cultured in the incubator. Cells were treated with 0.

The Effect of Gliding Arc Discharge Low-Temperature Plasma Pretreatment on Blueberry Drying.

This study evaluates the effects of gliding arc discharge low-temperature plasma (GAD-LTP) pretreatment on the drying performance and quality attributes of blueberries. Fresh blueberries were pretreated under varying conditions-treatment durations of 6 s, 12 s, and 18 s and power levels of 300 W, 600 W, and 900 W-prior to convective hot air drying at 65 °C. Results demonstrate that plasma pretreatment significantly reduced drying time, with an 18 s treatment at 900 W reducing drying time by 31.

Optimizing treatment selection in venous malformations through imaging-assisted sequential therapy: A case series analysis.

Objective: Venous malformations (VMs) are the most prevalent slow-flow congenital vascular anomalies. Effective management of VMs often necessitates individualized approaches, particularly for lesions with significant interstitial components. This study aims to evaluate a sequential treatment strategy combining sclerotherapy and open surgery, with guidance from ultrasound (US) and magnetic resonance imaging (MRI).

Metabolomics Analysis of the Mechanism of Yuquan Capsules in the Treatment of T2DM Rats Using UPLC/MS.

Purpose: Yuquan capsule (YQC) is a well-known proprietary Chinese medicine used for the treatment of type 2 diabetes mellitus. The aim of this study was to investigate the potential mechanism and efficacy of YQC in the treatment of T2DM by means of metabolomics.

Methods: Thirty-two male SD rats were randomly divided into four groups of control, type 2 diabetic mellitus (T2DM), metformin (Met), and YQC.

A sinomenine derivative alleviates bone destruction in collagen-induced arthritis mice by suppressing mitochondrial dysfunction and oxidative stress via the NRF2/HO-1/NQO1 signaling pathway.

Bone destruction in rheumatoid arthritis (RA) leads to significant disability, yet effective treatments are limited. Sinomenine (Sino) demonstrates anti-arthritic and bone-protective effects but requires high doses. In this study, we developed a Sino derivative, SINX, and evaluated its efficacy in RA.

Effects of nitrogen fertilizer basal-to-top-dressing ratios on maize straw decomposition, soil carbon and nitrogen, and bacterial community structure in different soil textures on the north china plain.

Straw return is a recognized agricultural practice that improves soil quality, reduces reliance on chemical fertilizers, and supports sustainable agriculture. Its effectiveness is influenced by microbial changes under varying soil properties and fertilization practices. In a wheat-maize rotation system, field experiments were conducted over 2 years in loam and clay loam soils with five fertilizer (N) application treatments (i.

Cxcl9 modulates aging associated microvascular metabolic and angiogenic dysfunctions in subcutaneous adipose tissue.

Microvascular aging, predominantly driven by endothelial cells (ECs) dysfunction, is a critical early event in cardiovascular diseases. However, the specific effects of aging on ECs across the microvascular network segments and the associated mechanisms are not fully understood. In this study, we detected a microvascular rarefaction and a decreased proportion of venular ECs in the subcutaneous adipose tissue of aged mice using light-sheet immunofluorescence microscopy and single-cell RNA sequencing.

Deep learning radiomics model based on contrast-enhanced MRI for distinguishing between tuberculous spondylitis and pyogenic spondylitis.

Purpose: This study aimed to develop and validate a deep learning radiomics nomogram (DLRN) to differentiate between tuberculous spondylitis (TS) and pyogenic spondylitis (PS) using contrast-enhanced MRI (CE-MRI).

Methods: A retrospective approach was employed, enrolling patients diagnosed with TS or PS based on pathological examination at two centers. Clinical features were evaluated to establish a clinical model.

Systems Biology Approach to Unraveling Transcriptomic Mechanisms of Ganfule Capsules in Ameliorating Nonalcoholic Fatty Liver Disease.

Aims: The primary objective of this study is to explore the impact of Ganfule (GFL), a traditional Chinese medicine, on differentially expressed genes (DEGs) linked to nonalcoholic fatty liver disease (NAFLD). By identifying potential biomarkers, we seek to enhance GFL's clinical efficacy through targeted pharmaceutical design.

Background: NAFLD a prevalent liver disorder, is often associated with obesity and metabolic syndrome.

Traditional Chinese medicine Chaiqinchengqi decoction for patients with acute pancreatitis: A randomized clinical trial.

Background: Chaiqinchengqi decoction, a traditional Chinese medicine, has shown promising effects in in vitro, animal and preliminary small human studies for acute pancreatitis, but evidence of clinical practice is limited.

Purpose: To investigate whether Chaiqinchengqi decoction could improve clinical outcomes in patients with acute pancreatitis.

Study Design: Prospective, pragmatic, randomized controlled trial.

"Raman plus X" dual-modal spectroscopy technology for food analysis: A review.

Raman spectroscopy, a nondestructive optical technique that provides detailed chemical information, has attracted growing interest in the food industry. Complementary spectroscopic methods, such as near-infrared (NIR) spectroscopy, nuclear magnetic resonance (NMR), terahertz (THz) spectroscopy, laser-induced breakdown spectroscopy (LIBS), and fluorescence spectroscopy (Flu), enhance Raman spectroscopy's capabilities in various applications. The integration of Raman with these techniques, termed "Raman plus X," has shown significant potential in agri-food analysis.

CTSG restraines the proliferation and metastasis of head and neck squamous cell carcinoma by blocking the JAK2/STAT3 pathway.

Background: Head and neck squamous cell carcinoma (HNSC) is recognized as the sixth most prevalent cancer globally, with around 900,000 new cases diagnosed each year. The management of HNSC poses significant challenges due to its rising incidence and suboptimal treatment outcomes in many patients. Thus, understanding the underlying molecular mechanisms that drive the onset and advancement of HNSC is crucial in order to steer the creation of novel treatment strategies.