Assembling Octahedral PtAg Clusters for High-Efficiency Circularly Polarized Luminescence.

Establishing atom-precise and controllable self-assembly of metal clusters to achieve high-efficiency circularly polarized luminescence (CPL) is especially fascinating, yet it creates considerable challenges. Here, two enantiomeric pairs of dimer clusters R/S-PtAg-green and R/S-PtAg-orange composed of two octahedral PtAg monomers through Pt-Pt bonds are constructed, which show a 28-fold increase in photoluminescence quantum yield (PLQY) compared with the reported monomer in solution. The solid-state chiral dimer R/S-PtAg-orange shows a PLQY of 87% without an aggregation-caused quenching effect.

Optimization Study of Nitrogen Injection Fire Prevention and Extinguishing Technology for Coal Spontaneous Combustion in Goaf.

The spontaneous combustion of residual coal in goafs poses a serious threat to mine safety. To examine this problem, taking a coal mine in Henan Province as an example, this study analyzes the air leakage laws and areas prone to coal spontaneous combustion (CSC) in the goaf through field observations and numerical simulations, employing the nitrogen injection to inert goaf method to prevent and control CSC. The results indicate that as the nitrogen injection location advances deeper into the goaf, the width of the oxidation zone initially decreases and then increases.

Effect of Benzoic Acid on Biogenic Gas Production with Different Rank Coals and the Fluorescence Spectra Characteristic of Produced Organic Products.

Biogas production was conducted using samples from different coal beds and laboratory-domesticated microbes to investigate the effect of the addition of benzoic acid on biogas production. Furthermore, the response properties of produced organic substances at different gas production stages were analyzed with ultraviolet-visible (UV-Vis) spectroscopy and three-dimensional fluorescence spectroscopy. The results showed that adding benzoic acid significantly enhanced the microbial gas production with different rank coals.

AdptDilatedGCN: Protein-ligand binding affinity prediction based on multi-scale interaction fusion mechanism and dilated GCN.

Predicting protein-ligand binding affinity is crucial for drug discovery. However, existing prediction methods often make insufficient use of the features of proteins and ligands, lack interactions between different information, and have difficulty in capturing and integrating both fine- and coarse-grained information of proteins and ligands at the same time. Therefore, we propose a deep learning method called AdptDilatedGCN, which fully interacts with protein and ligand features through multi-scale interaction and fusion mechanism, mining potential fine-grained and coarsely grained information and fusing it, combining skip connections and multi-scale fusion strategy to improve feature utilization and enhance features.

Ultrasonic guided wave nondestructive testing of anchorage quality of rebar resin bolt based on EMD-PCA.

Currently, the ultrasonic guided wave inspection of the anchoring quality of rebar resin bolts in coal mine tunnels faces issues such as rapid signal energy attenuation, waveform superposition of reflected waves, and waveform complexity, making it difficult to effectively identify anchoring quality. Therefore, a method combining Empirical Mode Decomposition (EMD) with Principal Component Analysis (PCA) is proposed for processing and analyzing ultrasonic guided wave detection signals. This study employs numerical simulation combined with laboratory testing, selecting low-frequency guided waves at 50 kHz with lower attenuation as excitation signals to simulate the propagation process of ultrasonic guided waves through rebar resin bolt and surrounding anchorage media.

Colossal permittivity in high-entropy CaTiO ceramics by chemical bonding engineering.

Dielectrics with high permittivity, low dielectric loss, and good temperature stability are crucial for electronic components to meet the ever-increasing application demands. However, challenges remain in further optimizing dielectric properties due to the correlation between these parameters. Here, we propose a chemical bonding engineering strategy in high-entropy CaTiO ceramics and realize colossal permittivity with low loss and excellent stability.

Using sulfur and oxygen isotope values to partition riverine sulfate sources and illustrate their responses to hydrological processes.

Orogenesis contributes to the elevation of highly eroded rock strata, whose interactions with the atmosphere, water, and biota result in the release of dissolved substances. The fluvial transport of dissolved sulfate (SO) from mountains to oceans is a critical component of the global sulfur cycle. However, anthropogenic activities have significantly increased the concentrations of sulfate and altered isotope compositions.

Highly Crystalline and Robust Donor-Acceptor Type Covalent Organic Frameworks for Long-life Sodium-Ion Battery Cathodes.

Covalent organic frameworks (COFs) hold great potential in sodium-ion battery cathodes. However, most reported COF-based electrodes show unsatisfying capacity and rate performance due to their limited redox site density, low crystallinity, and poor conductivity. Herein, a highly crystalline and robust donor-acceptor type COF with abundant redox active sites is developed by the polymerization of donor unit benzo[1,2-b:3,4-b″:5,6-b″']trithiophene-2,5,8-tricarbaldehyde) (BTT) and acceptor unit s-indacene-1,3,5,7(2H,6H)-tetrone (ICTO) (denoted as BTT-ICTO) for cathodic Na storage.

Shield construction safety risks and their interrelations analysis of subway tunnel undercrossing a river based on Grey-DEMATEL-ISM.

A large number of subway projects were designed and constructed by China's city government and more subway tunnels can hardly avoid undercrossing a river. Shield construction of subway tunnel undercrossing a river (STUR) is often in a complicated geological environment, which cause the construction process more prone to safety accidents. Hence, it is necessary to investigate the shield construction safety risks (SCSRs) of STUR in advance.

Ultrasensitive and ultra-selective room-temperature HS gas sensor based on CuO-loaded InO 2D porous nanosheets.

Developing a cost-effective sensing material capable of detecting HS with ultra-sensitivity, ultra-selectivity, and low detection limits at room temperature remains highly anticipated. In this paper, two-dimensional (2D) porous InO nanosheets were prepared by a simple solvothermal method, and then CuO was modified on the InO surface by impregnation. The CuO/InO two-dimensional porous structure allows the fabricated sensor to be highly sensitive to HS at room temperature.

MDM2 inhibitor induces apoptosis in colon cancer cells through activation of the CHOP-DR5 pathway, independent of p53 phenotype.

Introduction: Murine double minute 2 (MDM2), a key negative regulator of p53, forms a feedback loop with p53 to drive tumor progression, including colorectal cancer. Nutlin-3a, an MDM2 inhibitor, induces apoptosis in wild-type p53 tumors, but its effects on p53-mutated cancers and potential p53-independent apoptotic mechanisms remain unclear.

Methods: We investigated Nutlin-3a's effects on colon cancer cells with varying p53 phenotypes.

Effects of perceived control on thermal response and cooling carbon emissions across different operation modes.

Human psychological adaptation to indoor thermal conditions, particularly through perceived control, is increasingly recognized for its potential to influence building energy consumption. Despite this, its quantifiable impact remains unexplored. Here, we conducted a field survey (n = 922) using air conditioning (AC) access as a variable to examine how perceived control mediates occupants' thermal adaptation during summer.

Precursor-Directed Biosynthesis of Phenylpyrrole Analogues in .

Supplementation of -aminobenzoic acid and its derivatives into the culture medium of HPU-ZMN, a fungus isolated from the Yellow River wetland, resulted in the production of 21 novel phenylpyrrole derivatives designated as myropherroles A-U (-). Structural elucidation of these compounds was achieved through a comprehensive analysis of NMR and HRESIMS data. Notably, the myropherroles exhibit more diverse structures of the pyrrole compared to naturally occurring phenylpyrrole derivatives.

Clay mineral content modulates biogenic gas production in coal: divergent microbial responses in low- and medium-rank coals revealed by multi-omics.

The influence of clay mineral content on biogenic gas production in coal seams remains insufficiently understood. This study systematically investigated the mechanisms by which clay minerals affect biogas production in low- and medium-rank coals by integrating simulated biogas production experiments with multidimensional analytical techniques, including infrared spectroscopy, X-ray diffraction, scanning electron microscopy, gas chromatography-mass spectrometry, fluorescence spectroscopy, and metagenomic analysis. The results demonstrated that in low-rank coal, increasing the clay content from 2.

Neoadjuvant sintilimab and chemotherapy for resectable esophageal squamous cell carcinoma: a phase II clinical trial.

Background: Combination of anti-PD-1 monoclonal antibody with chemotherapy has been widely used as a first-line treatment for metastatic esophageal squamous cell carcinoma (ESCC). However, the efficacy of this therapeutic combination as a neoadjuvant intervention for resectable ESCC remains inadequately explored. This study aims to evaluate the efficacy and safety of sintilimab in combination with chemotherapy as a neoadjuvant therapy for ESCC.

Wetting Behaviors and Mechanisms of Coal Modified by Different Types of Surfactants under Intervention Using KCl.

The fracturing fluid with an added surfactant is conducive to backflow, and it is gaining more and more popularity in coal seam hydraulic fracturing projects. At the same time, the types and concentrations of mineral ions in the solution have an important impact on the backflow of the fracturing fluid. With K and Cl as representative ions of the mineralization degree of water solutions, understanding the mechanism of K and Cl on the wettability of surfactant-modified coal can provide a scientific theoretical basis for the backflow of the fracturing fluid.

Ligand Regulated the Coordination Environment of Cobalt-Group-MOF for Efficient Electrocatalytic Oxygen Reduction/Evolution Catalysis.

In recent years, the TMN moieties have demonstrated significant catalytic activity for oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) in graphene, CxNy, and other carbon-based two-dimensional (2D) support materials. Modifying the coordination number and species of N atoms in the TMN moieties has proven to be an effective approach to regulate their catalytic activity. In this research, by incorporating different triphenylene ligands, we have successfully constructed TMAB (TM = Co, Rh, Ir; A/B = N, O, S, Se) moieties with varying coordination environments within 2D metal organic frameworks (MOFs), which are linked by TM and triphenylene.

Adsorption, Structure, and Dynamics of DNA in Montmorillonite and Montmorillonite-Humic Acid: A Molecular-Level Insight.

Extracellular DNA (eDNA) has become a focus in public health, with soil recognized as a key reservoir where eDNA's mobility and stability are primarily controlled by clay minerals and organic matter. Montmorillonite (MMT) often interacts with humic acids (HA), forming MMT-HA complexes, although the molecular mechanisms behind DNA adsorption in these complexes remain unclear. Here, molecular dynamics simulations were used to examine the adsorption, diffusion, interfacial structure, and dynamics of DNA on MMT and MMT-HA complexes, revealing critical molecular interactions.

Research on agricultural grey water footprint/efficiency and identification of influencing factors in Henan Province.

Agricultural water pollution control is the key to alleviating the water crisis and promoting regional sustainable development. Grey water footprint (GWF) is an effective method that uses water consumption to measure water quality issues. In this study, we calculated agricultural GWF and its efficiency in 18 prefecture-level cities in Henan Province from 2001 to 2021 and analyzed their temporal and spatial characteristics using ArcGIS and the standard deviational ellipse (SDE) method.

A novel experimental study on impact tendency of real time borehole coal samples under lateral constrained compression.

The impact tendency of coal is a necessary condition for the occurrence of pressure bumping and a measure of the degree of damage. Through the combination of self-made lateral restraint device and high-speed camera, the variation law and failure mode of burst tendency index of coal samples under real-time drilling and pressure relief of lateral restraint under different loads were studied. The results show that: (1) With the increase of real-time drilling load under lateral constraints, the burst tendency index of coal samples changes.

Study on the influence of thermal environment on miners ' physiological and cognitive ability in deep mining face.

Objective: In order to reduce the impact of heat damage and reduce the incidence of accidents, this study will conduct regression analysis and cognitive ability test to quantify the relationship between temperature level and miners' physiological state, and monitor the impact of temperature on miners ' cognitive ability and working state.

Methods: Controlling different temperature levels as variables, with the help of PhysioPlux physiological recorder, two physiological indexes of heart rate variability and skin electricity were selected to study the physiological changes of miners caused by different temperature levels, and the influence of temperature on cognitive ability was studied based on cognitive ability test.

Results: (1) With the increase of temperature, the HRV time domain indexes RMSSD and SDNN of the subjects increased at different rates.

Deformation, failure, and crack propagation characteristics of fissured red sandstone under uniaxial compression condition.

Fissures are the main controlling factor of rock strength and crack propagation. To study the deformation, failure characteristics, and crack evolution in fissured red sandstone, uniaxial compression experiments were carried out on pre-fissured samples with different dip angles. The acoustic emission (AE) characteristics and complete stress-strain curves were obtained during the experiment, from which several valuable conclusions were drawn.

Haplotype-resolved genomes of Trichophyton mentagrophytes and Trichophyton tonsurans.

Dermatophytes have posed a significant health concern due to their ability to parasitize human and animal skin, hair, and nails, causing a spectrum of dermatological conditions. However, the absence of high-quality genomes hinders our understanding of the dermatophytes. In this study, we utilized the circular consensus sequencing (CCS) technology to generate haplotype-resolved, nearly-complete genomes for two representative dermatophytes, Trichophyton mentagrophytes and Trichophyton tonsurans.

The short-term economic influence analysis of government regulation on railway freight transport in continuous time.

Regulatory impact analysis, a crucial aspect of the development of railway transportation in China, has faced increasing challenges due to the complex nature of the transportation system and various influencing factors. This study proposes an improved comparative static model (ICSM) that intelligently integrates recursive principles and the Laplace transform to estimate the impact of macroeconomic policy reforms on the economic variables of China Railway Corporation (CRC). The ICSM integrates recursive principles and Laplace transform to solve complex conditions of eigenvalues as multiple roots and a coefficient matrix unable to diagonalize in the ICSM.

Widely Targeted Metabolomics Reveals the Bioactive Metabolites and Antioxidant Activities of Chinese Yam (Dioscorea opposita Thunb.) Peel.

Chinese yam (Dioscorea opposita Thunb. cv. Tiegun) has been utilized in traditional medicine and as a food source for centuries.