Challenging gender essentialism with animal examples: Reducing children's prejudice toward voice-based gender nonconformity.

Grounded in developmental intergroup theory, which highlights the role of essentialist thinking in the emergence of prejudice, this study examined whether reducing children's gender essentialism could decrease prejudice against speakers with gender-nonconforming (GN) voices. A total of 162 children aged 8-12 years participated in the study. The intervention group (N = 81) received three lessons illustrating diversity in sex-related traits and behaviors in the animal kingdom to challenge essentialist beliefs about gender roles, expression, and biological sex, whereas the control group received comparable lessons without gender-related content.

Results of Provincial Health Institutions Participating in Individual Monitoring Intercomparisons-China, 2022 to 2024.

To improve monitoring capabilities, China CDC organized individual monitoring intercomparisons, which provincial health institutions participated in from 2022 to 2024. The irradiation schemes and evaluation criteria were designed in accordance with GBZ 207-2016, "Testing criteria of personnel dosimetry performance for external exposure." The Type II (photon) test specified in the standard was selected as the intercomparison type, with Hp(10) as the target quantity.

Triatomines outside the Americas: a comprehensive dataset for the global surveillance of Chagas disease vectors.

Chagas disease is caused by , which is transmitted to mammals, including humans, mainly by insects of the subfamily Triatominae (Hemiptera: Reduviidae). Also known as "kissing bugs", the subfamily includes 159 species in 18 genera and five tribes. Although most species are in the Americas, here we present the first compilation of non-American triatomine occurrences.

Epidemiological characteristics and transmission dynamics of epidemic Japanese encephalitis in China: A modeling study.

Objectives: In recent decades, China has experienced successive epidemics of seasonal Japanese encephalitis (JE), with the Japanese encephalitis virus (JEV) particularly spreading continuously in rural and suburban areas.

Methods: Nationwide data on 9061 JE cases, mosquito abundance from 89 surveillance sites, and population movement between 337 cities during 2013-19 were obtained. Seasonal multivariate linear regression models including time trends and reconciliation terms representing annual and semiannual cycles were fitted to the weekly time series of JE cases, and the amplitude and peak time of the cycles were estimated.

The relationship between PAEs components profile of real-world household airborne dust and total DNA demethylation potential in vitro.

Phthalate esters (PAEs) existed in household environment globally, and household airborne dust PAEs (HD-PAEs) have garnered significant attention due to their endocrine-like toxicity. In on-site study investigating PAE contamination from 60 households across three Chinese cities, we analyzed 43 dust samples for specific PAE components and conducted comprehensive total DNA demethylation potential (TDP) toxicity assays. Ten congeners were detected across all cities (130.

BFD2 mediates inflammation, apoptosis, and pre-anxiety-like behaviors induced by acute Toxoplasma gondii infection.

Toxoplasma gondii infection induces anxiety in hosts during the chronic stage; however, its role in pre-anxiety-like behaviors during the acute stage remains poorly understood. This study investigates the role of Bradyzoite Formation Deficient 2 (BFD2), a transcription factor essential for tachyzoite-to-bradyzoite differentiation, in inflammation, apoptosis, and behavioral changes during acute T. gondii infection.

[Fast determination of maduramicin ammonium in serum by high performance liquid chromatography-tandem mass spectrometry].

To establish a high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method for the fast determination of maduramicin ammonium (MAD) in rat serum. In February 2024, rat serum samples were selected and directly injected after extraction and purification with methanol: acetonitrile (1: 1), separated on a C18 chromatographic column, and gradient-eluted using 0.1% formic acid aqueous solution -0.

[Visual analysis for published literature in the Chinese Journal of Industrial Hygiene and Occupational Diseases from 1983 to 2023].

To conduct a visual analysis of the papers published in the Chinese Journal of Industrial Hygiene and Occupational Diseases since its inception, and to understand the current situation and development trends in the field of occupational health and occupational diseases. A total of 9894 papers published in the Chinese Journal of Industrial Hygiene and Occupational Diseases from January 1, 1983 to December 31, 2023 were retrieved from China National Knowledge Infrastructure (CNKI) in February 2024. Non-academic literature was screened and excluded.

Association of Ambient Particulate Matter and Nitrogen Dioxide with Hospital Admissions for Parkinson's Disease: A Nationwide Case-Crossover Study in China.

Ambient particulate matter (PM) and nitrogen dioxide (NO) are both major air pollutants with potential neurotoxic effects. Beyond fine PM (PM), large population-based evidence on the associations of coarse PM (PM) and NO, especially co-exposure to high-concentration PM and NO, with hospital admissions for Parkinson's disease (PD) is crucial for PD risk management. In this time-stratified case-crossover study, patients with a principal discharge diagnosis coded of PD (G20) were identified.

A Single Amino Acid in PBP1a Drives High-Level Penicillin and Amoxicillin Resistance in Streptococcus suis.

Streptococcus suis is an important zoonotic pathogen that causes severe diseases in both humans and pigs, with β-lactam antibiotics serving as the primary treatment. However, resistance to penicillin and amoxicillin has been steadily increasing, and the mechanisms underlying their resistance remain poorly understood. In this study, we analyzed 534 S.

HLA-B*15:01-positive severe COVID-19 patients lack CD8 T cell pools with highly expanded public clonotypes.

Understanding host factors driving asymptomatic versus severe disease outcomes is of key importance if we are to control emerging and re-emerging viral infections. HLA-B*15:01 has been associated with asymptomatic SARS-CoV-2 infection in nonhospitalized individuals of European ancestry, with protective immunity attributed to preexisting cross-reactive CD8 T-cells directed against HLA-B*15:01-restricted Spike-derived S peptide (B15/SCD8 T-cells). However, fundamental questions remained on the abundance and clonotypic nature of CD8 T-cell responses in HLA-B*15:01-positive patients who succumbed to life-threatening COVID-19.

Combined detection of foodborne pathogens in irrigation water in Jiangsu, China.

Numerous foodborne disease outbreaks have been attributed to the consumption of fresh produce contaminated with foodborne pathogens. Contaminated irrigation water is a well-established source of bacterial and viral contamination during primary production and is frequently responsible for the contamination of fresh produce. However, efficient methods for the simultaneous detection of bacterial and viral pathogens present in irrigation water are still scarce.

Preliminary assessment of the therapeutic potential of staphylococcal enterotoxin-like W via biological activity and TCR binding sites analysis.

Staphylococcal enterotoxin-like W (SElW) is a novel, widely prevalent enterotoxin-like protein that functions as a classical staphylococcal superantigen (SAg) and has been shown to exacerbate infections caused by the epidemic clone CC398. However, the genetic distribution and amino acid polymorphisms, biological and antitumor activity, and T cell receptor (TCR) binding sites of SElW in strains prevalent in China have not been investigated. The carrier rate and distribution of were determined by PCR, the stability and antitumor activity of recombinant SElW (rSElW) protein were evaluated.

Breakfast consumption behavior was positively associated with cognitive function in Chinese adults aged 55 years and above.

Objectives: This study aims to investigate the relationship between breakfast consumption behavior and cognitive function in Chinese adults aged 55 years and above, and the mediating effect of diet quality.

Methods: Data were drawn from the China Health and Nutrition Survey (CHNS) 1997, 2000, 2004, 2006, 2015, and 2018. Participants aged 55 years and above who had at least two waves of completed data on dietary measures and cognitive assessments were eligible.

Rational design of respiratory syncytial virus dimeric F-subunit vaccines in protein and mRNA forms.

Background: Respiratory syncytial virus (RSV) poses a significant public health threat, particularly to children and the elderly. Two protein-based vaccines and one mRNA vaccine have been approved, all targeting the prefusion conformation of the fusion (F) trimer. However, it has been reported that the epitope activity of the F protein gradually declines during storage, resulting in a reduction of the vaccines' immunogenicity.

EAAT2 dysfunction mediates acrylamide-induced excitotoxicity and neuronal damage in a SH-SY5Y/U251 co-culture model.

Acrylamide (ACR) is a pervasive environmental and workplace contaminant with established neurotoxic effects but unclear pathogenic mechanisms. In this study, we screened for potential ACR binding targets associated with neurotoxicity and identified the astrocytic glutamate transporter EAAT2. Molecular docking and dynamics simulations revealed that ACR interacts stably with the glutamate-binding pocket of EAAT2, potentially impairing transport function.

The influence and lag-effect of temperature and precipitation on the incidence and mortality of tuberculosis, 2000-2021: an observational study.

Background: Tuberculosis (TB) remains a major global health concern, particularly in low-and middle-income countries. Climate change may influence TB burden through effects on human health, living conditions, and pathogen transmission, yet its long-term impact remains underexplored.

Methods: This observational study integrated data on temperature and precipitation obtained from NCEI/NOAA, TB burden from the Global Burden of Disease Study 2021, and socio-economic covariates from the World Bank open data platform.

Short-term association between hot nights and mortality: a multicountry analysis in 178 locations considering hourly ambient temperature.

Background: The rise in hot nights over recent decades and projections of further increases due to climate change underscores the critical need to understand their impact. This knowledge is essential for shaping public health strategies and guiding adaptation efforts. Despite their significance, research on the implications of hot nights remains limited.

Biological characteristics and epidemiological insights into the zoonotic potential of Colpodella spp.: a scoping review.

Background: Colpodella species are classified within the domain Eukaryota, specifically under the order Colpodellida, family Colpodellaceae, and genus Colpodella, which are close relative of the phylum Apicomplexa. These organisms are unicellular, predatory flagellates. In recent years, their frequent detection in animal tissues, vector insect samples, and particularly in human has garnered significant attention as an emerging zoonotic threat.

Awareness, Preference, and Acceptance of HPV Vaccine and Related Influencing Factors Among Guardians of Adolescent Girls in China: A Health Belief Model-Based Cross-Sectional Study.

Background: Cervical cancer poses a threat to the health of women globally. Adolescent girls are the primary target population for HPV vaccination, and guardians' attitude towards the HPV vaccine plays a significant role in determining the vaccination status among adolescent girls.

Objectives: This study aimed to explore the factors influencing guardians' HPV vaccine acceptance for their girls and provide clues for the development of health intervention strategies.

A Review of Avian Influenza Virus Exposure Patterns and Risks Among Occupational Populations.

Avian influenza viruses (AIVs) pose significant risks to occupational populations engaged in poultry farming, livestock handling, and live poultry market operations due to frequent exposure to infected animals and contaminated environments. This review synthesizes evidence on AIV exposure patterns and risk factors through a comprehensive analysis of viral characteristics, host dynamics, environmental influences, and human behaviors. The main routes of transmission include direct animal contact, respiratory contact during slaughter/milking, and environmental contamination (aerosols, raw milk, shared equipment).

Molecular Characterization of Tick-Borne Pathogens in Jiangxi Province: A High Prevalence of , and in in Cattle from Ganzhou City, China.

, , and species are emerging tick-borne pathogens that cause zoonotic diseases, including rickettsiosis, anaplasmosis, and ehrlichiosis in both human and animal populations. This study aimed to investigate the prevalence of these pathogens in cattle-associated ticks from Ganzhou City, Jiangxi Province, China. Through molecular characterization using multilocus sequence analysis (16S , , , and genes), we analyzed 392 ticks collected from March to September in 2022.

Synergistic Effects of MTHFR, MTRR, and MTR Gene Variants on Serum Folate Levels and Cognitive Function in Chinese Preschoolers: A Cross-Sectional Study.

: Subnormal folate levels have a detrimental impact on the growth and development of preschoolers. We aimed to investigate the association between independent/synergistic effects of the gene polymorphisms (methyltetrahydrofolate reductase (MTHFR) and polymorphisms, alongside methionine synthase reductase (MTRR) polymorphism and the methionine synthase (MTR) polymorphism) and serum folate levels as well as cognitive levels in Chinese preschoolers aged 5-7 years. : Data were sourced from 614 children, acquired through the "Long-term Health Effects Assessment Project of Infants and Toddlers Nutritional Pack (LHEAITNP)" program were used.