Breakfast consumption behavior was positively associated with cognitive function in Chinese adults aged 55 years and above.

Objectives: This study aims to investigate the relationship between breakfast consumption behavior and cognitive function in Chinese adults aged 55 years and above, and the mediating effect of diet quality.

Methods: Data were drawn from the China Health and Nutrition Survey (CHNS) 1997, 2000, 2004, 2006, 2015, and 2018. Participants aged 55 years and above who had at least two waves of completed data on dietary measures and cognitive assessments were eligible.

Association between Life's Essential 8 and hyperuricemia in the Chinese elderly.

Background And Objectives: Life's Essential 8 (LE8) is a comprehensive indicator that evaluates cardiovascular health (CVH). There have been limited studies on the relationship between LE8 and hyperuricemia (HUA). This study explored the association and dose-response relationship between LE8 and HUA among elderly people in China.

[Mechanism of elaidic acid-induced lipid accumulation in vascular smooth muscle cells].

Objective: To investigate the molecular mechanisms underlying EA(elaidic acid)-induced lipid accumulation in VSMCs(vascular smooth muscle cells).

Methods: CCK-8 assay determined the effects of EA(0-2.8 mmol/L) on MOVAS(murine aortic vascular smooth muscle cells)to select experimental concentrations.

Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome.

Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder in women of reproductive age, marked by hyperandrogenism, ovulatory dysfunction, and insulin resistance, accompanied by significant metabolic disturbances, including glycolytic dysfunction, mitochondrial impairment, and increased oxidative stress. In granulosa cells (GCs), disrupted glycolysis impairs follicular development and compromises oocyte quality, exacerbating reproductive and metabolic abnormalities. At the molecular level, dysregulated energy-sensing pathways, such as AMPK and mTOR, reduce glucose uptake, lower ATP generation, and enhance oxidative stress, fueling disease progression.

Healthy sleep without insomnia may go beyond sleep duration for achieving successful aging in Chinese older adults: a cross-sectional study.

Objective: Successful aging (SA) is a major challenge of population aging. Exploring modifiable factors becomes the focus of promoting SA. We aimed to understand SA status and determine association between sleep and SA in China.

From Pathophysiology to Treatment: The Role of Ferroptosis in PCOS.

Polycystic ovary syndrome (PCOS) is a prevalent gynecological endocrine and metabolic disorder in women, with an incidence rate of 10-13%. The etiology of PCOS is multifaceted, involving genetic predisposition, environmental influences, lifestyle factors, and endocrine metabolic dysregulation. Iron, a critical mineral, not only plays a role in regulating female physiological functions and the progression of PCOS but also requires careful management to avoid deficiency.

Dietary Vitamin Intake Among Chinese Adults - 10 PLADs, China, 2022-2023.

What Is Already Known About This Topic?: Previous surveillance data from 2015-2017 showed that Chinese adults aged 18 to 59 years had mean daily vitamin intakes of 406.8 μg retinol equivalent (RE) for vitamin A, 36.7 mg for vitamin E, 0.

Macroelements Intake in Chinese Adults - 10 PLADs, China, 2022-2023.

What Is Already Known About This Topic?: The Chinese Nutrition and Health Surveillance in 2015-2017 reported that among adults aged 18-59 years, the average daily intake was 328.3 mg of calcium, 251.8 mg of magnesium, 5,681.

Physical Activity and Sedentary Behavior Among Chinese Adults - 10 PLADs, China, 2022-2023.

What Is Already Known About This Topic?: The prevalence of insufficient physical activity (PA) among Chinese adults has shown an upward trend, reaching 22.3% in 2018. Leisure time PA (LTPA) constitutes a minimal proportion of total physical activity patterns.

[Dietary iron, zinc, selenium, and copper intake and food sources among adult residents in 10 provinces(autonomous regions) of China in 2022-2023].

Objective: To understand the dietary iron, zinc, selenium, and copper intake and food sources of residents aged 18 years and above in 10 provinces(autonomous regions) of China.

Methods: Using the data of China Development and Nutrition Health Impact Cohort Survey from 2022 to 2023, 9981 residents aged 18 and above with complete three consecutive days with 24 h dietary recalls were selected as the research subjects. The intake status and food sources of dietary iron, zinc, selenium, and copper were analyzed and compared with the estimated average requirement(EAR) of iron, zinc, selenium and copper for Chinese residents.

[Intake of nutrient supplements among adult residents in 10 provinces(autonomous regions) of China in 2022-2023].

Objective: To understand the intake status of nutrient supplements in 10 provinces(autonomous regions), so as to provide scientific evidence for guiding the rational use of nutrient supplements.

Methods: In this study, nutrient supplement is defined as raw materials including the categories in the "Health Food Raw Materials Catalog, Nutrient Supplements(2023 Edition)", and the product forms include health foods, OTC micronutrient supplements, and others. The scope of nutrient supplements in this study was defined.

[Distribution and epidemic trends of chronic multimorbidity among adult residents in 10 provinces (autonomous regions)of China in 2009-2023].

Objective: To describe the prevalence and epidemic trends of several chronic multimorbidy among adult residents in 10 provinces(autonomous regions)of China over the past 14 years, and to analyze their multimorbidity patterns.

Methods: According to the fasting blood physiological and biochemical tests, physical measurements and questionnaires of 17 000 adult residents aged 18 years and above who were surveyed in 4 rounds of follow-up surveys in 2009, 2015, 2018 and 2023, the relevant indicators and disease history information of obesity, hypertension, diabetes mellitus, dyslipidemia, hyperuricemia, and various chronic diseases were obtained. Descriptive analysis was carried out to identify and compare several common combinations of multimorbidity in the population with 2 or more chronic disease conditions and the changing trends of 4 rounds of surveys.

[Status and epidemic trends of major chronic metabolic diseases among adult residents in 10 provinces (autonomous regions) of China in 2009-2023].

Objective: To analyze the status and epidemic trends of major chronic metabolic diseases among adults.

Methods: Using the "China Health and Nutrition Survey"(2009-2018)/"China Development and Nutrition Health Impact Cohort Survey"(2022-2023), adults aged 18 years old and above from 10 provincial regions were selected as the study subjects. Those with missing demographic information and disease diagnosis were removed, and a total of 34 982 people were finally included from 2009, 2015, 2018 and 2023 waves.

[Prevalence and trends of overweight, obesity, and central obesity among adult residents in 10 provinces (autonomous regions) of China in 2000-2023].

Objective: To describe the prevalence of overweight, obesity, and central obesity among adult residents aged 18 years and above in 10 provinces(autonomous regions) of China in 2023, and to analyze the trends in 2000-2023.

Methods: Adults aged 18 and over with complete height, weight and waist circumference measurements who participated in the 2000-2018 China Health and Nutrition Survey and the 2022-2023 China Development and Nutrition Health Impact Cohort Survey from the same 10 provinces(autonomous regions) were selected as the study subjects. Overweight, obesity, pre-central obesity, and central obesity were defined according to the Chinese Adult Weight criteria(WS/T 428-2013).

[Food intake among adult residents in 10 provinces (autonomous regions) of China in 2022-2023].

Objective: To describe the food intake among adult residents in 10 provinces(autonomous regions) of China.

Methods: Data was collected from the financial project China Development and Nutrition Health Impact Cohort Survey in 2022-2023. The method of three consecutive 24-h dietary recalls and weighing were used to collect foods and condiments intake data.

[Macronutrient intake status and food sources in adult residents from 10 provinces (autonomous regions) of China in 2022-2023].

Objective: To analyze dietary energy and macronutrient intake and food sources of adult residents in 10 provinces(autonomous regions) in China.

Methods: The data were derived from the 2022-2023 China Development and Nutrition Health Impact Cohort Survey and the China Health and Nutrition Survey, and adults(≥18 years) with completed demographic characteristics and dietary data were selected. Energy, macronutrient intakes, and their contribution to total energy, and protein food sources by characteristics of subjects were analyzed, which were further compared with the acceptable macronutrient distribution range(AMDR) and the estimated average requirement of protein.

Age and Gender Disparities in the Association of Long-Term Dietary Choline and Choline Compound Intakes with Incident Cognitive Decline in Middle-Aged and Older Chinese Adults: A Prospective Cohort Study.

: The neuroprotective role of dietary choline during adulthood has not yet been conclusively proven. This study aims to investigate the influence of long-term choline and its constituent intakes on cognitive decline in the Chinese population. : A total of 4502 subjects (≥55 years) with at least two waves of completed data and without cognitive decline at baseline were selected from the China Health and Nutrition Survey 1997-2018.

Vertical Association Between Dietary Total Choline and L-alpha-glycerylphosphorylcholine and the Cognitive Function in Chinese Adults Aged over 55, Result from China Health and Nutrition Survey 1997-2018.

Background: With the aging process in China showing an accelerated trend, cognitive decline and impairment have become a major issue in older people. Dietary choline supplement may be a changeable lifestyle to improve this situation.

Method: We analyzed 7659 adults aged over 55 in the China Health and Nutrition Survey (CHNS), evaluated cognitive function by the global cognition score, and found the association between cognitive function and dietary intake of total choline or L-alpha-glycerylphosphorylcholine (GPC).

Dietary Choline Intake Is Beneficial for Cognitive Function and Delays Cognitive Decline: A 22-Year Large-Scale Prospective Cohort Study from China Health and Nutrition Survey.

Pre-clinical studies have discovered the neuroprotective function and the benefit for cognitive function of choline. However, it remains unclear whether these benefits observed in animal studies also work in humans. The aims of this study are to examine the effects of dietary choline intake on cognitive function and cognitive decline during ageing in middle-aged and elderly Chinese.

Combined impact of elevated C-reactive protein levels and dyslipidemia on stroke: a CHNS prospective cohort study.

Background: The objective of this study was to examine whether the combination of elevated levels of C-reactive protein (CRP) and dyslipidemia increased the risk of stroke among middle-aged and older adult individuals in China.

Methods: This study utilized longitudinal data from the China Health and Nutrition Survey (CHNS) collected in 2009, 2015, and 2018. A total of 8,023 participants aged ≥40 years (3,595 males and 4,428 females) were included.

The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer.

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with a high degree of malignancy and poor prognosis. Tumor-associated macrophages (TAMs) have been identified as significant contributors to the growth and metastasis of TNBC through the secretion of various growth factors and chemokines. Salvianolic acid A (SAA) has been shown to have anti-cancer activities.

Diet Mediate the Impact of Host Habitat on Gut Microbiome and Influence Clinical Indexes by Modulating Gut Microbes and Serum Metabolites.

The impact of external factors on the human gut microbiota and how gut microbes contribute to human health is an intriguing question. Here, the gut microbiome of 3,224 individuals (496 with serum metabolome) with 109 variables is studied. Multiple analyses reveal that geographic factors explain the greatest variance of the gut microbiome and the similarity of individuals' gut microbiome is negatively correlated with their geographic distance.

[Changes in mild cognitive impairment and sociodemographic disparity among adults aged 55 years and above in 4 provinces of China].

Objective: To investigate the changes in mild cognitive impairment(MCI) and sociodemographic disparity among adults aged 55 years and above in 4 provinces of China.

Methods: A total of 4687 adults aged 55 years and above from Community-based Cohort Study on Nervous System Disease who did not have Alzheimer's disease, participated in both rounds of the survey, and had complete baseline sociodemographic data and two rounds of data on cognitive function were selected. Generalized estimation equations were used to analyse the effect of sociodemographic factors on MCI.