WRKY transcription factors participate in abiotic stress responses mediated by sugar metabolism.

Plant abiotic stress refers to the unfavorable effects on plants caused by any abiotic factors in a specific environment, such as drought, high temperature, low temperature, etc., which cause disruption of plant physiology and metabolism, and seriously affect the growth and yield of plants. Mounting evidence demonstrates that WRKY transcription factors modulate plant abiotic stress responses by regulating sugar metabolic pathways.

Treatment effectiveness of hydroxychloroquine in patients with primary Sjögren's syndrome: a real-world Study.

Objective: This study aimed to evaluate the effectiveness of hydroxychloroquine (HCQ) in reducing disease activity and explore its optimal dosing and combination therapies in patients with primary Sjögren's syndrome (pSS).

Methods: We conducted a retrospective study of 1089 hospitalized pSS patients. Multivariable logistic regression was used to estimate adjusted odds ratios (ORs) with 95% confidence intervals (CIs).

Lipid Oxidation of Stored Brown Rice Changes Ileum Digestive and Metabolic Characteristics of Broiler Chickens.

Long-term storage may induce lipid oxidation in brown rice and impact its utilization in animal diets. One-day-old male Ross 308 broiler chickens (with an initial body weight of 20 g) were randomly divided into three groups: corn-based diet (Corn), fresh brown rice-based diet (BR1) and stored brown rice-based diet (BR6), with 8 replicates of 10 birds per pen, in a 42-day feeding trial. The results showed that lipid oxidation indexes increased and fatty acid composition changed significantly in BR6 ( < 0.

Machine learning-based radiomics analysis in enhancing CT for predicting pathological subtypes and WHO staging of thymic epithelial tumors: a multicenter study.

This study is aimed to develop predictive models for classifying thymic epithelial tumor (TET) histological subtypes (A/AB/B1, B2/B3, C) and WHO stages (I-IV) using radiomics features derived from contrast-enhanced CT scans. These models were validated on multicenter external datasets to improve preoperative diagnosis and guide treatment decisions. A total of 257 patients diagnosed with TET between January 2013 and April 2024 were retrospectively analyzed, with 181 cases from the First Affiliated Hospital of Soochow University served as the training cohort and 76 cases from the Second Affiliated Hospital used as an external test set.

Comparative effects of arithmetic, speech, and motor dual-task walking on gait in stroke survivors: a cross-sectional study.

Background: The application of dual-task walking paradigms for gait assessment in stroke patients is critical, where varying concurrent tasks may elicit distinct gait patterns of dual-task interference. This study assessed the acute effects of different types of dual tasks on gait in stroke patients during task performance, informing occupational, and physical therapists about care recommendations to prevent patients from falling and improve their balance function in daily life.

Methods: A total of 19 stroke patients (52.

Polyvinyl chloride microplastic triggers bidirectional transmission of antibiotic resistance genes in soil-earthworm systems.

The diffusion and distribution of ubiquitous microplastics and antibiotic resistance genes (ARGs) in soil ecosystems are easily influenced by earthworm activity. However, minimal research exists on the bidirectional dissemination of ARGs in the soil-earthworm ecosystems under microplastic stress. Focusing on the typical microplastic polyvinyl chloride (PVC) microspheres in simulated soil-earthworm (Eisenia fetida) systems, we characterized the PVC-triggered interactive transmission of ARGs between earthworm guts and their dwelling soils using shotgun metagenomics and qPCR methodologies.

A wearable obstacle avoidance device for visually impaired individuals with cross-modal learning.

It is challenging for wearable obstacle avoidance devices to simultaneously meet practical demands of high reliability, rapid response, long-lasting duration, and usable design. Here we report a wearable obstacle avoidance device, comprising a set of self-developed glasses (weighing  ~400 grams, including an  ~80 grams battery) and a common smartphone. Specifically, the glasses collect the multi-modal data for comprehensive environmental perception, including video and depth modalities, and implement a depth-aided video compression module.

Jiajian Shuyu pills effectively ameliorate cognitive impairment via regulating the inflammation of microglia in an Alzheimer's disease mouse model.

Ethnopharmacological Relevance: Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by progressive cognitive decline and behavioral impairments in the elderly. Microglia, the resident immune cells of the central nervous system, play a crucial role in modulating the pathological processes associated with AD. Jiajian Shuyu Pills (JJSYP) are frequently employed in the treatment of AD, purportedly by enhancing the physiological functions of human tissues and organs to modulate the immune response.

Nonlinear Association Between the Liver Fat Content and the Risk of Hyperuricemia in Prediabetic Individuals: Evidence from Cross-Sectional Health Screening Data in China.

Purpose: The impact of hepatic lipid accumulation on hyperuricemia presents an intriguing research avenue, particularly in light of existing studies linking obesity with hyperuricemia. Nevertheless, there remains a scarcity of quantitative investigations into the correlation between liver fat content (LFC) and hyperuricemia among prediabetic cohorts, notably within the Chinese demographic.

Patients And Methods: This cross-sectional study was conducted at the Health Management Center of Henan Provincial People's Hospital between January 2019 and December 2023, involving 2,950 pre-diabetic participants.

Correction: Linolenic acid ameliorates sarcopenia in by promoting mitophagy and fighting oxidative stress.

Correction for 'Linolenic acid ameliorates sarcopenia in by promoting mitophagy and fighting oxidative stress' by Lu Zhang , , 2023, , 1498-1509, https://doi.org/10.1039/D2FO02974J.

Characterization of dynamic features in the walking videos of patients with adolescent idiopathic scoliosis based on moving entropy.

Adolescent idiopathic scoliosis (AIS), which typically occurs in patients between the ages of 10 and 18, can be caused by a variety of reasons, and no definitive cause has been found. Early diagnosis of AIS or timely recognition of progression is crucial for the prevention of spinal deformity and the reduction of the risk of surgery or postponement. However, it remains a significant challenge.

Enhanced Reaction Kinetics in Stationary Two-Phase Flow through Porous Media.

Understanding the interaction between multiphase flow and reactive transport in porous media is critical for many environmental and industrial applications. When a nonwetting immiscible phase is present within the pore space, it can remain immobile, which we call unsaturated flow, or move, resulting in multiphase flow. Previous studies under unsaturated flow conditions have shown that, for a given flow rate, the product of a mixing-driven reaction increases as wetting phase saturation decreases.

The dietary inflammatory index is positively associated with low muscle mass in adults: an analysis of NHANES.

Introduction: Using the data taken from the National Health and Nutrition Examination Survey (NHANES) database, we explored the relationship between the dietary inflammatory index (DII) and low muscle mass (LMM) in adults.

Methods: We examined 20,424 adults ≥ 20 years old from the 1999-2006 and 2011-2018 NHANES. We hypothesized that the DII is positively associated with the risk of LMM in adults.

Effect of tacrolimus with mycophenolate mofetil or cyclophosphamide on the renal response in systemic lupus erythematosus patients.

Objective: This study aimed to determine the therapeutic efficacy of tacrolimus (TAC) with mycophenolate mofetil (MMF) or cyclophosphamide (CYC) on the renal response in systemic lupus erythematosus (SLE) patients.

Methods: A retrospective cohort study based on medical data was conducted among SLE patients who took at least one of the following medicines in 2010-2021: TAC, MMF and CYC. The odds ratio (OR) and 95% confidence interval (CI) were calculated, and the synergistic interaction was estimated using logistic regression models.

Abnormal developmental of hippocampal subfields and amygdalar subnuclei volumes in young adults with heavy cannabis use: A three-year longitudinal study.

Background: Differences in the volumes of the hippocampus and amygdala have consistently been observed between young adults with heavy cannabis use relative to their non-using counterparts. However, it remains unclear whether the subfields of these functionally and structurally heterogenous regions exhibit similar patterns of change in young adults with long-term heavy cannabis use disorder (CUD).

Objectives: This study aims to investigate the effects of long-term heavy cannabis use in young adults on the subregional structures of the hippocampus and amygdala, as well as their longitudinal alterations.

Recent Advances of Metal-Organic Framework for Heavy Metal Ions Adsorption.

Heavy metal ion wastewater is a pressing and inescapable issue that is closely related to human health and ecological security due to its toxicity, carcinogenicity, and the unmanageable property of this type of wastewater. Metal-Organic Frameworks (MOFs) are a class of crystalline nanoporous materials with flexible designability and controllability, showing great potential in the field of adsorption and purification of heavy metals in wastewater. In this Perspective, we first discuss the harm of different heavy metal ions and briefly expound virtues of MOFs for pollutant adsorption.

Exploring the poverty-reduction benefits of agricultural machinery socialization services in China: Implications for the sustainable development of farmers.

Sustainable development is crucial for alleviating poverty among farmers. In this study, we examined the impact, and the mechanism underlying this impact, of the adoption of agricultural machinery services by farmers on their relative poverty from a multidimensional poverty perspective by employing the logit and ordered logit models and the Karlson-Holm-Breen (KHB) method. These results indicate that adopting agricultural machinery services can significantly reduce the probability of relative poverty among farmers, thereby expediting the sustainability of rural development.

Association of metabolic syndrome and its components with Parkinson's disease: a cross-sectional study.

Background: The interrelation between metabolic syndrome (MetS) and Parkinson's disease (PD) likely arises from shared pathological mechanisms. This study thus aims to examine the impact of MetS and its components on PD.

Methods: This study utilized data extracted from the National Health and Nutrition Examination Survey database spanning 1999 to 2020.

Interactions between nitrate reductase 2 and catalase 1 fine-tune disease resistance in cassava.

Cassava (Manihot esculenta) is one of the most important tuber crops, used for food, starch, and bio-energy. However, it is susceptible to a number of diseases, especially cassava bacterial blight. Nitric oxide (NO) and hydrogen peroxide (H2O2) regulate plant growth and development, as well as stress responses.

Causal association between helicobacter pylori and atherosclerosis: a two-sample Mendelian randomization.

Background: Helicobacter pylori (H. pylori), according to a number of recent observational studies, is connected to atherosclerosis (AS). However, the link between H.

Factors associated with 25-hydroxyvitamin D level in Chinese hospitalized patients with systemic lupus erythematosus: a retrospective cohort study.

We aimed to investigate the factors associated with vitamin D deficiency and changes in 25 (OH)D levels, as well as the impact of those changes on disease activity and renal function among SLE patients. This retrospective cohort study was based on the medical records of SLE patients hospitalized between 2010 and 2021. We collected relevant information from this patient population.