Publications by authors named "Zhijie Qian"
Int J Rheum Dis
April 2024
Article Synopsis
- The study looked at hospitalized patients with systemic lupus erythematosus (SLE) to understand how often severe infections occur and what factors influence their initial and recurrent episodes.
- Out of 1051 patients, 15.6% had severe infections upon admission, and during a 4.1-year follow-up, 10.8% experienced severe infections again, with prior infections increasing the likelihood of reinfection.
- Key risk factors for recurrent severe infections included low immunoglobulin levels, positivity for anti-dsDNA antibodies, and the use of specific medications like cyclophosphamide.
- The study concluded that patients with a history of severe infection and low immunoglobulin levels are at higher risk for future infections.
