Impact of Reactive Chlorine on Atmospheric Oxidative Capacity in a Snowy Polluted Environment.

Reactive chlorine species can significantly influence the formation of secondary air pollutants. Due to limited observational data, their contribution to haze formation in cold environments remains poorly constrained. In this study, we conducted field measurements of reactive chlorine species in snowy Northeast China, a region frequently affected by wintertime haze events.

Mindfulness-based interventions in oncology: A scoping review of outcomes and applications.

Cancer significantly impacts patients' physical and mental health, leading to a wide range of effects from physical pain to psychological issues such as anxiety and depression, severely diminishing their quality of life. As an emerging psychosomatic intervention, mindfulness interventions have gained increasing attention. This scoping review systematically searches and filters relevant literature, covering databases from their inception to January 2025, aiming to comprehensively outline the application, research characteristics, and main outcomes of mindfulness interventions in cancer recovery.

Highly Stable Electrosynthesis of Hydrogen Peroxide Adapted to Fluctuating Renewable Energy.

The integration of renewable energy with electrocatalytic technology affords an effective pathway to reduce carbon emissions and enhance energy efficiency, thereby promoting the green electrification of the chemical industry. However, the inherent contradiction between the fluctuating nature of renewable energy and the need for stable operation in electrochemical processes significantly hinders their development and implementation. To mitigate this, we propose a robust two-electron oxygen reduction reaction system using O-coordinated Co single-atom catalysts for the electrosynthesis of environmentally friendly hydrogen peroxide.

A Smart Textile-Based Tactile Sensing System for Multi-Channel Sign Language Recognition.

Sign language recognition plays a crucial role in enabling communication for deaf individuals, yet current methods face limitations such as sensitivity to lighting conditions, occlusions, and lack of adaptability in diverse environments. This study presents a wearable multi-channel tactile sensing system based on smart textiles, designed to capture subtle wrist and finger motions for static sign language recognition. The system leverages triboelectric yarns sewn into gloves and sleeves to construct a skin-conformal tactile sensor array, capable of detecting biomechanical interactions through contact and deformation.

AlCoCrFeNi High-Entropy Alloys Enable Simultaneous Electrical and Mechanical Robustness at Thermoelectric Interfaces.

The interface between high-performance thermoelectric materials and electrodes critically governs the conversion efficiency and long-term reliability of thermoelectric generators under high-temperature operation. Here, we propose AlCoCrFeNi high-entropy alloys (HEA) as barrier layers to bond Cu-W electrodes with p-type skutterudite (p-SKD) thermoelectric materials. The HEA/p-SKD interface exhibited excellent chemical bonding with a stable and controllable reaction layer, forming a dense, defect-free (Fe,Ni,Co,Cr)Sb phase (thickness of ~2.

Composition Analysis and In Vitro Investigation on Antioxidant, α-Amylase, and Pancreatic Lipase Inhibitory Activities of Major Mushrooms in Qinling Mountains.

Edible mushrooms exhibit a range of pharmacological activities, including anticancer, antimicrobial, antioxidant, anti-obesity, and hepatoprotective effects, thereby holding significant potential for applications in the development of functional foods. This study aimed to evaluate the bioactivities of methanolic extracts from various edible mushrooms (MEMs) found in the Qinling Mountains, China, with the following species used as materials: Suillus granulatus (L.) Roussel (S.

The association between triglyceride-glucose index, atherogenic index of plasma, systemic immune-inflammation index, and mortality in patients with acute coronary syndrome: the direct effects of glucose-lipid metabolism and U-shaped immune modulation in mortality risk.

Background: Cardiovascular disease (CVD) remains the leading global cause of death, with inflammation and glycolipid dysregulation as key drivers of atherosclerosis progression. While triglyceride-glucose index (TyG) and Atherogenic Index of Plasma (AIP) are linked to cardiovascular risk, their prognostic value in Acute Coronary Syndrome (ACS) patients, particularly Acute Myocardial Infarction (AMI) patients, and mediating role of systemic inflammation remain unclear. This study investigates the relationship between glycolipid metabolism, systemic inflammation, and mortality in ACS patients.

Combination of culture and glycyrrhizic acid alleviates the toxic effects of multi-mycotoxins on broiler production performance and nutrient metabolism.

Introduction: Mycotoxins in animal diets cause a lot of economic loss in animal husbandry annually. The objective of this experiment was to evaluate the effect of combination of culture and glycyrrhizic acid (CANCGA) on alleviating multi-mycotoxin toxicity for broiler production performance and nutrient metabolism.

Methods: A total of 500 one-day-old male broilers were randomly divided into 10 groups, 5 replications in each group and 10 broilers in each replication.

Application of Nanotechnology in TACE Treatment of Liver Cancer.

Liver cancer, particularly hepatocellular carcinoma (HCC), remains a global health challenge with limited therapeutic options for advanced stages. Transarterial chemoembolization (TACE), the first-line treatment for intermediate and advanced-stage HCC, faces limitations such as incomplete tumor embolization and systemic toxicity. This review synthesizes recent advancements in nanotechnology to address these challenges, focusing on nanoparticles (NPs) as embolic agents, drug carriers, and imaging contrast agents.

Revealing the different effects induced by antipsychotic drugs using an electrochemical microsensor to measure exocytosis in living cells.

Real-time monitoring of neurotransmitter release in living cells is crucial for understanding neural functions and the efficacy of drug actions. Here, we developed an electrochemical microsensor chip using a multidimensional nanosensitive material (MNG-1) that detects dopamine (DA) with high sensitivity, enabling real-time analysis of exocytosis in living cells. Our sensor-based technique does not require advanced equipment and can detect single exocytotic events using a standard electrochemical workstation and a small Faraday cage, allowing for rapid and statistically significant data collection.

Harnessing screw dislocations in shell-lattice metamaterials for efficient, stable electrocatalysts.

Developing highly active and robust catalysts remains a critical challenge for the industrial realization and implementation of nitrate reduction. Here, we proposed a screw dislocation-mediated three-dimensional (3D) printing strategy for scalable, integrated manufacturing of metamaterial catalysts. Specifically, screw dislocation was introduced into the 3D printing process to mediate the simultaneous synthesis of 3D architecture and chiral surface nanostructures, effectively eliminating conventional heterointerfaces.

Global, Regional, and National Burden of Atopic Dermatitis: Insights From the Global Burden of Disease Study 2021.

The 2017 Global Burden of Disease (GBD) report identified atopic dermatitis (AD) as the skin disease with the highest disease burden, assessed in terms of disability-adjusted life-years (DALYs), and a modest increase in the number of AD-associated DALYs was observed in 2019 compared to 2017. This study aims to provide updated insights from the GBD 2021 database. Data on the prevalence and DALYs of AD in 2021 were extracted from the GBD database.

Impact of Gaura parviflora invasion on urban wildness biodiversity: a campus green patch case study.

Urban wilderness has gradually emerged as a hot spot for urban ecological research due to its crucial role in maintaining urban ecosystem services and protecting biodiversity. Compared to natural areas, urban wildnesss are more susceptible to invasions by alien species, which pose a threat to the functionality of the urban ecosystem. Currently, our understanding of biodiversity within various types of urban wilderness is not comprehensive, and the laws governing biodiversity changes due to alien species invasions remain unclear.

Effects of modified corn straw supplementation on laying performance, egg quality, immune response, antioxidant capacity, lipid metabolism and intestinal microbiota of post-peak laying hens.

Corn straw is potential dietary fiber-rich resources, which can be used as functional feed after appropriate modification. This research investigated the impact of modified corn straw (MCS) on production performance, egg quality, immune responses, antioxidant capacity, lipid metabolism, intestinal morphology and microbiota of post-peak laying hens. 225 Hy-Line brown laying hens aged 50-wk were divided into three groups: basal diet, basal diet added with 0.

Xanthosine alleviates myocardial ischemia-reperfusion injury through attenuation of cardiomyocyte ferroptosis.

Background: Ischemic heart disease remains a leading cause of morbidity and mortality worldwide, with myocardial ischemia-reperfusion (I/R) injury significantly contributing to cardiomyocyte death and poor outcomes post-acute myocardial infarction (AMI). Emerging evidence highlights metabolic changes during myocardial injury, particularly in purine metabolism. This study investigates the protective role of xanthosine (XTS), a purine metabolism intermediate, in alleviating I/R injury.

Temporary Nanoencapsulation of Mammalian Cells With Silk Ionomers Using Electrostatic Layer-By-Layer Deposition Technique.

Nanoencapsulation of mammalian cells is a novel approach offering a protective microenvironment for cells, enabling their sustained viability and function in hostile or non-physiological conditions. This protection is particularly valuable in applications, such as cell therapy, tissue engineering, and immunotherapy, where maintaining cell functionality is critical for therapeutic success. The encapsulation process involves surrounding cells with a biomaterial barrier that acts as an artificial cell wall, shielding them from immune system attacks, toxic substances, and mechanical stress, while still allowing the exchange of essential nutrients, gases, and waste; thus, preserving cell viability and function during biochemical processing and applications.

Tandem reaction-adsorption separation of perfluorinated cyclopropane/propane mixtures.

Separating perfluorinated cyclopropane/propane mixtures is critical yet challenging for sustainably producing high-purity perfluropropane in the advanced electronics industry. Conventional one-step adsorption separation methods lack proper selectivity due to similar molecular sizes and properties. We introduce a tandem reaction-adsorption approach with ultrahigh selectivity and low-pressure uptake.

Biosafety considerations triggered by genome-editing technologies.

Since the discovery of the double helix structure of deoxyribonucleic acid (DNA), significant progress has been made in engineering technologies such as gene analysis and editing, greatly promoting the development of biomedical research and clinical applications. In recent years, the rapid development of genome-editing technologies, especially the clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR-Cas9) system, have brought unprecedented opportunities for biomedical research and clinical applications. However, with the widespread application of genome-editing technologies, biosafety issues have gradually attracted the attention of the scientific community and the public.

Innate immune role of IL-6 in influenza a virus pathogenesis.

Interleukin-6 (IL-6), a pleiotropic cytokine, is induced by infection of influenza A virus (IAV), where it plays a pivotal role in immune defense and the regulation of inflammation. IAV induces IL-6 transcription upon recognition by pattern recognition receptors, which activate downstream signaling cascades, leading to the activation of transcription factors. Activated transcription factors subsequently regulate the expression of IL-6 in innate immune cells, such as macrophages, dendritic cells, and epithelial cells.

Qidong Huoxue decoction protects against acute lung injury by promoting SIRT1-mediated p300 deacetylation.

Background: Qidong Huoxue Decoction (QD), a traditional Chinese medicine, has been used clinically to treat acute lung injury (ALI); however, its anti-inflammatory mechanisms remain poorly understood.

Purpose: This study aimed to elucidate the mechanism by which QD mitigates ALI, focusing on its anti-inflammatory effects.

Methods: A combination of serum pharmacochemistry, acetyl-proteomic sequencing, and experimental validation was used to investigate the therapeutic effects of QD on ALI.

SlXTH1, a xyloglucan endotransglucosylase/hydrolase in halophyte Suaeda liaotungensis, negatively regulates Arabidopsis seed germination under salt stress.

Seed germination is accompanied by cell wall remodeling. Cell wall remodeling proteins, xyloglucan endotransglucosylase/hydrolase (XTHs), play a crucial role in embryo cell growth and endosperm weakening during seed germination. Nonetheless, the function of XTHs in seed germination under salt stress has not been reported.

Gipc3 Mutation Might Cause Sensorineural Hearing Loss by Inhibiting Mitophagy in Inner Ear Hair Cells.

Sensorineural hearing loss (SNHL) has a high degree of genetic heterogeneity, with numerous mutated genes that contribute to deafness. GIPC3 gene is one of the mutated genes that can cause congenital hearing loss, which has been identified in recent years; however, the exact mechanism behind this condition remains unclear. Mitophagy is the process of selectively encapsulating and lysing damaged or dysfunctional mitochondria in order to prevent the accumulation of damaged mitochondria from damaging the cells and is of great importance in the maintenance of homeostasis in the inner ear.

The Effect of Non-Thermal Processing on the Fate of Pathogenic Bacteria and Hidden Hazardous Risks.

Non-thermal processing encompasses a range of emerging food technologies, including high-pressure processing (HPP), pulsed electric field (PEF), cold atmospheric plasma (CAP), high-pressure carbon dioxide (HPCD), and ultrasound (US). Unlike traditional thermal processing or chemical preservatives, these methods offer advantages such as lower energy consumption, enhanced environmental sustainability, and effective microbial inactivation, thereby extending food shelf life. Moreover, they can better preserve the nutritional integrity, color, flavor, and texture of food products.

Mutations of two AhTT8 genes reduce the accumulation of anthocyanins and confer the white testa of peanut (Arachis hypogaea L.).

Anthocyanins and proanthocyanidins (PAs), which determine the color of peanut seed coats, not only offer protection to plants under biotic and abiotic stress but also contribute to human health. The white testa peanut contains lower levels of anthocyanins and PAs, yet the mechanisms underlying the white testa phenotype in peanuts remain largely unknown. In the current study, two homologous peanut AhTT8 genes, namely AhTT8_AA and AhTT8_BB, were identified as the key genes controlling the seed coat color of peanuts through BSA-seq analysis and fine mapping.