Mindfulness-based interventions in oncology: A scoping review of outcomes and applications.

Cancer significantly impacts patients' physical and mental health, leading to a wide range of effects from physical pain to psychological issues such as anxiety and depression, severely diminishing their quality of life. As an emerging psychosomatic intervention, mindfulness interventions have gained increasing attention. This scoping review systematically searches and filters relevant literature, covering databases from their inception to January 2025, aiming to comprehensively outline the application, research characteristics, and main outcomes of mindfulness interventions in cancer recovery.

AAGP integrates physicochemical and compositional features for machine learning-based prediction of anti-aging peptides.

Aging is a natural phenomenon characterized by the loss of normal morphology and physiological functioning of the body, causing wrinkles on the skin, loss of hair, and compromised immune systems. Peptide therapies have emerged as a promising approach in aging studies because of their excellent tolerability, low immunogenicity, and high specificity. Computational methods can significantly expedite wet lab-based anti-aging peptide discovery by predicting potential candidates with high specificity and efficacy.

Familial coaggregation and shared genetic influence between major depressive disorder and gynecological diseases.

The mechanism underlying the co-occurrence of major depressive disorder (MDD) and gynecological diseases remains unclear. This study aimed to investigate the familial co-aggregation and shared genetic loading between MDD and gynecological diseases, namely dysmenorrhea, endometriosis, uterine leiomyomas (UL), and polycystic ovary syndrome (PCOS). Overall, 2,121,632 females born 1970-1999 with parental information were enrolled from the Taiwan National Health Insurance Research Database (NHIRD); 25,142 same-sex twins and 951,779 persons with full-sibling(s) were selected.

A population-based study of familial coaggregation and shared genetic etiology of psychiatric and gastrointestinal disorders.

Background: It has been proposed that having a psychiatric disorder could increase the risk of developing a gastrointestinal disorder, and vice versa. The role of familial coaggregation and shared genetic loading between psychiatric and gastrointestinal disorders remains unclear.

Methods: This study used the Taiwan National Health Insurance Research Database; 4,504,612 individuals born 1970-1999 with parental information, 51,664 same-sex twins, and 3,322,959 persons with full-sibling(s) were enrolled.

Associations of polygenic risks, depression, and obesity-related traits in Taiwan Biobank.

Background: The comorbidity of obesity and major depressive disorder (MDD) may be attributable to a bidirectional relationship and shared genetic influence. We aimed to examine the polygenic associations between obesity and MDD and to characterize their corresponding impacts on the obesity mechanism.

Methods: Genome-wide genotyping was available in 106,604 unrelated individuals from Taiwan Biobank.

Boron-Substituted Coronene: Intriguing Geometric and Electronic Properties, and Large Nonlinear Optical Response.

By substituting boron atoms for selected carbon atoms of a graphene quantum dot (GQD) model, namely a coronene molecule, the substituent effect on its geometric and electronic structure, as well as nonlinear optical response has been systemically investigated in theory. Our computations reveal that the boron substitution leads to a similar noncentrosymmetric apophysis structure for the boron-substituted coronene in singlet and triplet states. Noticeably, due to the small energy difference of 2.

Outpatient Hypertension Control and Prescribing Habits for Hypertension in Taiwan.

Background: Hypertension control is of the utmost importance for reducing cardiovascular risk. In Taiwan, the hypertension control rate of the general population is low (25%). We investigated the factors affecting outpatient hypertension control to determine whether the low control rate stems from clinician unawareness or inadequate public education.

Effects of Tai Chi rehabilitation on heart rate responses in patients with coronary artery disease.

The objective of the present study was to evaluate the effect of a six-month Tai Chi (TC) exercise cardiac rehabilitation program on two prognostic factors of cardiac events, rate-pressure product and rate-pressure product reserve, in patients with coronary artery disease (CAD). Patients (N = 54) with CAD were recruited from the clinics of cardiology and cardiovascular surgery at a regional hospital in Taiwan. Twenty-two of them enrolled in the TC rehabilitation program which consisted of weekly 90-min sessions of Yang's style TC for six months in addition to receiving usual care.

Takotsubo cardiomyopathy as an underlying mediator of myocardial infarction with normal coronary arteries.

Objective: The purpose of the present study was to describe our experience with myocardial infarction with normal coronary arteries (MINCA) with regards to the prevalence, clinical characteristics, possible underlying etiologies (including Takotsubo cardiomyopathy, TCM) and the short- and long-term outcomes associated with this condition.

Methods: We retrospectively analyzed the records of 596 consecutive patients presenting with acute myocardial infarction over a 4-year period and identified 24 patients (14 female, 10 male) with angiographically normal coronary arteries. Demographic and clinical variables and outcomes were reviewed.

A multicenter study of the association of serum uric acid, serum creatinine, and diuretic use in hypertensive patients.

Background: Individuals with hypertension and hyperuricemia have an increased risk of coronary artery disease and cerebral vascular disease as compared to patients with normal uric acid levels. Our aim is to determine the prevalence of hyperuricemia in hypertensive patients in Taiwan, and whether serum uric acid (SUA) is associated with changes in renal function in patients with hypertension.

Methods: We studied 2145 hypertensive patients receiving medical treatment, assessed the prevalence of hyperuricemia, and determined the independent risk factors for SUA.

The effect of t'ai chi exercise on autonomic nervous function of patients with coronary artery disease.

Objective: The objective of this study was to evaluate the effect of t'ai chi (TC) on heart rate variability (HRV) from baseline to 9 months in patients with coronary artery disease (CAD).

Design: A comparative trial was undertaken comparing the acute and long-term effect of TC on HRV in patients with CAD.

Participants: Sixty-one (61) subjects with CAD undergoing percutaneous intervention or coronary bypass grafting for a period of more than 1 month were recruited from the clinics of cardiology and cardiovascular surgery at Chia-Yi Christian Hospital, Taiwan.