Localized Surface Plasmon Resonance Effect for Superior Fenton-Like Catalysis.

Nanomaterial-mediated Fenton-like reactions, central tools to address the increasing prevalence of micropollutants, predominantly use chemically stable hydrogen peroxide (HO) as the oxidant despite its high activation energy that leads to rather low catalytic activity. Here, we report that the efficiency of Fenton-like reaction can be substantially increased through the localized surface plasmon resonance (LSPR) effect, initiated by a plasmonic catalyst comprising a ruthenium nanocluster anchored on titanium dioxide nanobelt (TNB-Ru). Experimental results and simulation studies unravel the formation of LSPR on the catalyst surface upon visible light irradiation, which promises the conversion of photon energy into localized heat, contributing to remarkable catalytic performance and high utilization rate of HO (40%) in Fenton-like reaction.

Organic acid accumulation pattern and its key genes in Chinese cherry fruits.

Background: Chinese cherry [Cerasus pseudocerasus (Lindl.) G.Don], an economically important fruit species native to southwestern China, plays a key role in regional agriculture.

Mechanisms of SNP and melatonin effects on antioxidant and chlorophyll metabolism in postharvest okra.

Okra fruit rapidly undergoes chemical deterioration after harvest, necessitating effective preservation strategies. This study represents the first comprehensive investigation combining transcriptomic analysis with biochemical assessment to elucidate how SNPs and MT affect antioxidant capacity and chlorophyll metabolism in okra. MT + SNP treatment most effectively preserved fruit quality by reducing weight loss, maintaining color parameters, decreasing oxidative stress markers (HO, MDA), and enhancing antioxidant enzyme activities (SOD, CAT, POD, APX).

Targeted Metabolomics and Widely Targeted Quantitative Lipidomics Reveal Synergistic Metabolic Interference in Adipose Tissue After the Combined Chronic Exposure to Bisphenol A Substitutes, Bisphenol S and Bisphenol F, and Fructose in Male Rats.

The combined effect of environmental exposure and dietary behavior plays a vital role in the occurrence of diseases. Bisphenol S (BPS) and bisphenol F (BPF) are the most commonly used substitutes for bisphenol A (BPA). Previous studies have shown that the combined exposure to BPA and fructose caused significant disturbances in glycolipid metabolism in adipose tissue, however, the interference caused by the combined exposure to BPS and fructose or BPF and fructose on adipose tissue is still unclear.

Effects of traditional Chinese medicine collapse stains therapy combined with burn ointment on wound healing, inflammation, and pain mediator levels in patients with second degree burns.

Objective: To investigate the effects of traditional Chinese medicine(TCM) collapse stains therapy combined with burn ointment on wound healing, inflammation, and pain mediator levels in patients with second-degree burns.

Methods: This was a retrospective study. A total of 84 patients with second degree burns treated at Xingtai Third Hospital from January 2022 to December 2023 were selected as the study subjects.

An Efficient Electrochemiluminescence Biosensor Based on Ru(bpy)@AuNPs@SWCNTs for miRNAs Detection Using a Dual Engine-Triggered DNA Walker.

The diagnosis and treatment of acute pancreatitis remain challenging due to the limitations of diagnostic methods, which often result in delayed treatment and suboptimal outcomes. This underscores the need for innovative diagnostic strategies to enable early detection and improve therapeutic interventions. Electrochemiluminescence (ECL)-based biosensors have emerged as a promising solution, offering advantages such as cost-effectiveness, ease of use, and high sensitivity.

UPLC-QqQMS based targeted metabolomics reveal combination impact on metabolism caused by bisphenol AF and fructose combined exposure in male mice.

Bisphenol AF (BPAF), a fluorinated alternative to the plasticizer bisphenol A (BPA), is found in both the environment and the human body. Fructose is one of the sweeteners that has been widely used in recent years. Prior research has verified that the combined exposure to fructose and BPA considerably worsened the impact on glycolipid metabolism.

Identifying palliative home care needs of patients with advanced cancer: a cross-sectional study.

Background: Home-based palliative care is an ideal model for providing continuous, effective, and timely care at the patient's home. However, the timely recognition of palliative home care needs remains a clinical challenge, and few studies have described the characteristics of palliative care needs and quality of life at home.

Objectives: To identify the palliative home care needs of patients with advanced cancer and explore the influencing factors in addressing these needs.

Two colorimetric LAMP systems for nucleic acid-based diagnostics.

Background: This study introduces an advanced 8-well loop-mediated isothermal amplification (LAMP) system specifically designed for the automated colorimetric detection of SARS-CoV-2. Incorporating two distinct configurations having either three light-emitting diodes (LEDs) with varying emission wavelengths per well, paired with a photodiode detector, or utilizing white LED illumination with a red, green, and blue (RGB) sensor. The colorimetric LAMP aims to provide a more accessible and rapid diagnostic tool than traditional fluorescence methods due to the system's simplicity.

High-Entropy Metal Interstitials Activate TiO for Robust Catalytic Oxidation.

Substitution metal doping strategies are crucial for developing catalysts capable of activating O, but the leaching of metal dopants has greatly hindered their potential for extensive oxidation reactions under mild conditions. Here, the study develops an entropy-increase strategy to synthesize high-entropy metal (Mg, Ca, Mn, Fe, and Co) interstitial functionalized anatase TiO (HE-TiO) nanosheets, demonstrating remarkable degradation efficiency across a wide pH range and exceptional stability in a flow-by electro-catalytic reactor. Relative to that of pristine TiO, the intense lattice distortion on the (001) plane, an average lattice expansion of 2% on the (100) plane, and decrease of second shell peak of X-ray absorption spectra serve as compelling evidence for the formation of metal interstitials in HE-TiO.

Microfluidics chips fabrication techniques comparison.

This study investigates various microfluidic chip fabrication techniques, highlighting their applicability and limitations in the context of urgent diagnostic needs showcased by the COVID-19 pandemic. Through a detailed examination of methods such as computer numerical control milling of a polymethyl methacrylate, soft lithography for polydimethylsiloxane-based devices, xurography for glass-glass chips, and micromachining-based silicon-glass chips, we analyze each technique's strengths and trade-offs. Hence, we discuss the fabrication complexity and chip thermal properties, such as heating and cooling rates, which are essential features of chip utilization for a polymerase chain reaction.

Phosphate-Induced Acidic Microenvironment for Improved Contaminant Removal during FeS Oxygenation.

The coexistence of mackinawite (FeS) and phosphate is widely observed in natural systems. However, the underlying mechanism regarding how phosphate influences the environmental behavior of FeS, especially during the FeS oxygenation in aquatic systems, remains in its fancy. This study for the first time reported that the presence of phosphate, even at a low concentration of 0.

Risk Factors of Postoperative Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery in the Recent 10 Years: Clinical Analysis of 6229 Patients.

Background: Postoperative atrial fibrillation (POAF) is a common complication after coronary artery bypass grafting (CABG) that prolongs hospitalization and increases expenses.

Hypothesis: Perioperative risk factors may predict POAF.

Methods: From March 2015 to January 2023, 6229 patients who underwent isolated CABG and were in sinus rhythm before CABG were included in this retrospective study.

Physicochemical Properties and Biological Activities of Polysaccharides from Panax Notoginseng Separated by Fractional Precipitation.

The dried root of Panax notoginseng is a medicinal and food ingredient. P. notoginseng polysaccharides (PNPs) have physicochemical properties, which have not been fully elucidated.

Amorphous-Crystalline Interface Induced Internal Electric Fields for Electrochromic Smart Window.

Balancing optical modulation and response time is crucial for achieving high coloration efficiency in electrochromic materials. Here, internal electric fields are introduced to titanium dioxide nanosheets by constructing abundant amorphous-crystalline interfaces, ensuring large optical modulation while reducing response time and therefore improving coloration efficiency. Aberration-corrected high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) reveals the presence of numerous amorphous-crystalline phase boundaries in titanium dioxide nanosheets.

Effect of remimazolam on intra-operative hypotension: Systematic review and meta-analysis of randomised controlled trials.

Background: Hypotension is common during anaesthesia. Increasing number of studies have reported that remimazolam may be associated with lower incidence of intra-operative hypotension compared with other anaesthetics. However, the results remain controversial.

Ase1 selectively increases the lifetime of antiparallel microtubule overlaps.

Microtubules (MTs) are dynamically unstable polar biopolymers switching between periods of polymerization and depolymerization, with the switch from the polymerization to the depolymerization phase termed catastrophe and the reverse transition termed rescue. In presence of MT-crosslinking proteins, MTs form parallel or anti-parallel overlaps and self-assemble reversibly into complex networks, such as the mitotic spindle. Differential regulation of MT dynamics in parallel and anti-parallel overlaps is critical for the self-assembly of these networks.

Discovery of delayed gas production after implantation of a continuous-flow left ventricular assist device and a preliminary exploration of the mechanisms of its occurrence.

Objective: To characterize the gas production phenomenon in the animal model of left ventricular assist device (LVAD), and study its mechanism.

Methods: An bubble precipitation experiment was conducted, and the blood samples of Parma spp. animals were divided into ordinary group and oxygen-enriched group according to whether they were oxygenated or not at the time of blood collection, and a static control group was set up respectively.

Diagnostic value of multimodal cardiovascular imaging technology coupled with biomarker detection in elderly patients with coronary heart disease.

Coronary heart disease is a common disease in the elderly and has a complex pathogenesis, which complicates the clinical diagnostic process. Thus, enhancing the diagnostic efficiency for coronary heart disease is imperative to improve the life expectancy of the elderly. This study aimed to explore the diagnostic value of multimodal cardiovascular imaging technology coupled with biomarker detection in elderly patients with coronary heart disease.

An integrated microfluidic platform for nucleic acid testing.

This study presents a rapid and versatile low-cost sample-to-answer system for SARS-CoV-2 diagnostics. The system integrates the extraction and purification of nucleic acids, followed by amplification via either reverse transcription-quantitative polymerase chain reaction (RT-qPCR) or reverse transcription loop-mediated isothermal amplification (RT-LAMP). By meeting diverse diagnostic and reagent needs, the platform yields testing results that closely align with those of commercial RT-LAMP and RT‒qPCR systems.

Patterned Micro Flexible Supercapacitors based on the Rapid Transfer-Printing Method.

Developing a simple and rapidly preparative method for patterned flexible supercapacitors is essential and indispensable for the swift advancement of portable devices integrated with micro devices. In this study, we employed a cost-effective and rapid fabrication method based on transfer-printing technology to produce patterned micro flexible supercapacitors with various substrates. The resulting flexible micro supercapacitors not only allow for customized patterns with strong flexibility and resistance to bending, while maintaining a certain level of performance, but also facilitate the creation of diverse circuits to tailor voltage and current to specific requirements.

SPEED: an integrated, smartphone-operated, handheld digital PCR Device for point-of-care testing.

This study elaborates on the design, fabrication, and data analysis details of SPEED, a recently proposed smartphone-based digital polymerase chain reaction (dPCR) device. The dPCR chips incorporate partition diameters ranging from 50 μm to 5 μm, and these partitions are organized into six distinct blocks to facilitate image processing. Due to the superior thermal conductivity of Si and its potential for mass production, the dPCR chips were fabricated on a Si substrate.

Directional Formation of Reactive Oxygen Species Via a Non-Redox Catalysis Strategy That Bypasses Electron Transfer Process.

A broad range of chemical transformations driven by catalytic processes necessitates the electron transfer between catalyst and substrate. The redox cycle limitation arising from the inequivalent electron donation and acceptance of the involved catalysts, however, generally leads to their deactivation, causing substantial economic losses and environmental risks. Here, a "non-redox catalysis" strategy is provided, wherein the catalytic units are constructed by atomic Fe and B as dual active sites to create tensile force and electric field, which allows directional self-decomposition of peroxymonosulfate (PMS) molecules through internal electron transfer to form singlet oxygen, bypassing the need of electron transfer between catalyst and PMS.

Regulating Surface Dipole Moments of TiO for the pH-Universal Cathodic Fenton-Like Process.

Although electro-Fenton (EF) processes can avoid the safety risks raised by concentrated hydrogen peroxide (HO), the Fe(III) reduction has always been either unstable or inefficient at high pH, resulting in catalyst deactivation and low selectivity of HO activation for producing hydroxyl radicals (OH). Herein, we provided a strategy to regulate the surface dipole moment of TiO by Fe anchoring (TiO-Fe), which, in turn, substantially increased the HO activation for OH production. The TiO-Fe catalyst could work at pH 4-10 and maintained considerable degradation efficiency for 10 cycles.