[Synergistic Effect of Agricultural Pollution and Carbon Reduction and Their Driving Factors in Henan Province].

In the context of the "dual-carbon" goal and shaping of new advantages in green agricultural development, empirical references and policy recommendations are provided for agricultural agglomeration regions, mainly in grain-producing areas such as Henan Province, to explore the green, low-carbon transformation and high-quality sustainable development of agriculture. Based on the coupled coordination model, the GTWR model was used to explore the influence mechanism and spatiotemporal heterogeneity of the two synergies and their drivers, with a view to promoting the green, low-carbon and sustainable development of agriculture in Henan Province by taking pollution reduction and carbon reduction as a common goal. The results showed that： Between 2010 and 2022, agricultural carbon emissions and agricultural surface pollution emissions in Henan Province showed a slow increase, followed by a slow decline and a gradual stabilization trend, with obvious spatial and temporal heterogeneity.

Resolving the structure and assembly of the honeybee silk heterotetrameric coiled coil.

Coiled coil structures, first proposed by Crick in the 1950s, are protein structural motifs found across diverse biological systems. Honeybee silk was among the earliest identified coiled coils, with X-ray diffraction studies in the 1960s revealing its characteristic helical packing. Decades of research have provided insights into silk composition and formation, yet the molecular details of its coiled coil assembly and final structure remained unresolved.

Online risk scores for pre- and postoperative prediction of early recurrence in hepatocellular carcinoma patients undergoing conversion liver resection after tyrosine kinase inhibitors and immune checkpoint inhibitors therapy.

Background: Conversion therapy with tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) offers the potential for curative resection in unresectable hepatocellular carcinoma (HCC). However, early recurrence (≤2 years) after conversion liver resection remains a major concern. This study aimed to develop and validate online preoperative and postoperative risk scores to predict early recurrence in patients undergoing conversion liver resection.

Unique Bioinspired Nanowire Structures for Dual-Modal Optoelectronic Electronic Skin.

As initial basic applications expand into more complex and diverse fields, including prosthesis, the metaverse, and information encryption, the diversification, multifunctionality, and customization of electronic skin (e-skin) have increasingly become prominent research trends. However, most e-skins focus on achieving higher performance and a broader response range, lacking functionality and mode customization options. Here, a mode designable bioinspired e-skin is reported, utilizing a mechanical strategy combined with interface assembly technology, and achieving the integration of optical and electrical sensing capabilities in single functional material.

Multilevel Inter-modal and Intra-modal Transformer network with domain adversarial learning for multimodal sleep staging.

Sleep staging identification is a fundamental task for the diagnosis of sleep disorders. With the development of biosensing technology and deep learning technology, it is possible to automatically decode sleep process through electroencephalogram signals. However, most sleep staging methods do not consider multimodal sleep signals such as electroencephalogram and electrooculograms signals simultaneously for sleep staging due to the limitation of performance improvement.

Actuator Structure Design for Flexible Photothermal-Electric Device and Multifunctional Self-Powered Sensor.

Flexible photothermal-electric devices hold great promise for applications such as solar energy conversion and wearable electronics, thanks to their ability to generate green energy, sense temperature, and enhance wearing comfort. However, creating sufficient temperature gradients for optimal power generation along with high-performance multifunctional sensing capabilities remains a significant challenge. In this study, we demonstrate a flexible photothermal-electric device with an exceptional temperature gradient created by a thermal actuator through light-induced thermal deformation.

Revealing the Oxidative Stress-Related Molecular Characteristics and Potential Therapeutic Targets of Schizophrenia through Integrated Gene Expression Data Analysis.

Schizophrenia is a severe mental disorder characterized by oxidative stress imbalances. The underlying mechanisms of oxidative stress-related gene expression in schizophrenia require further investigation. Additionally, the diagnosis of schizophrenia lacks sensitive and specific biomarkers as well as predictive models for assessing susceptibility.

A Powerful Regulator to Enhance Electrocatalytic Reaction Kinetics and Thermodynamics: The Ordered Hetero-Nanowire.

Optimizing the thermodynamics of electrode reactions is a valid strategy for achieving superior electrocatalysts for direct methanol fuel cells (DMFCs). However, as the catalyst downsizes to the nanoscale, the influence of mass transfer kinetics is pronounced in improving electrocatalytic activity. Herein, an ordered hetero-nanowire (NW) regulator that couples the virtues of kinetics and thermodynamics is reported.

The impact of rhizosphere soil microorganisms on the medicinal active ingredients of from different regions.

Aims: Analyzing the rhizosphere microbial community structure of from different regions and its correlation with the accumulation of main medicinal active ingredients, this study aims to explore the impact of rhizosphere soil microorganisms on the effective components of , providing a scientific basis for the high-quality and high-yield cultivation of .

Methods And Results: The rhizosphere soil of three-year-old was used as the research object. High-throughput sequencing technology was employed to analyze the rhizosphere bacterial and fungal community structures.

The association between aldosterone and lipid profiles in patients with primary aldosteronism.

Previous studies have yielded inconsistent findings regarding the comparison of lipid profiles in patients with primary aldosteronism (PA) and essential hypertension (EH), and there is a limited understanding of the association between plasma aldosterone concentration (PAC) and lipid profiles across various populations. 270 patients with PA and 598 patients with EH diagnosed at the Second Affiliated Hospital of Nanchang University from January 2020 to June 2021 were consecutively included. After 1:1 propensity score matching by sex, age, and body mass index (BMI), 267 PA and 267 EH patients were ultimately enrolled in the study.

Efficient Methanol Oxidation Kinetics Enabled by an Ordered Heterocatalyst with Dual Electric Fields.

Induced by a sharp-tip-enhanced electric field, periodical nanoassemblies can regulate the reactant flux on the electrode surface, efficiently optimizing the mass transfer kinetics in electrocatalysis. However, when the nanoscale building blocks in homoassemblies are arranged densely, it results in the overlap and reduction of the local electric field. Herein, we present a comprehensive kinetic heteromodel that simultaneously couples the sharp-tip-enhanced electric field and charge transfer electric field between different building blocks with any arrangement densities.

Bridging bioengineering and nanotechnology: Bone marrow derived mesenchymal stem cell-exosome solutions for peripheral nerve injury.

Peripheral nerve injury (PNI) is a common disease that is difficult to nerve regeneration with current therapies. Fortunately, Zou demonstrated the role and mechanism of bone marrow derived mesenchymal stem cells (BMSCs) in promoting nerve regeneration, revealing broad prospects for BMSCs transplantation in alleviating PNI. We confirmed the fact that BMSCs significantly alleviate PNI, but there are shortcomings such as low cell survival rate and immune rejection, which limit the wide application of BMSCs.

Mechanically Stable and Damage Resistant Freestanding Ultrathin Silver Nanowire Films with Closely Packed Crossed-Lamellar Structure.

One-dimensional (1D) functional nanowires are widely used as nanoscale building blocks for assembling advanced nanodevices due to their unique functionalities. However, previous research has mainly focused on nanowire functionality, while neglecting the structural stability and damage resistance of nanowire assemblies, which are critical for the long-term operation of nanodevices. Biomaterials achieve excellent mechanical stability and damage resistance through sophisticated structural design.

Saliva Proteome, Metabolome and Microbiome Signatures for Detection of Alzheimer's Disease.

As the burden of Alzheimer's disease (AD) escalates with an ageing population, the demand for early and accessible diagnostic methods becomes increasingly urgent. Saliva, with its non-invasive and cost-effective nature, presents a promising alternative to cerebrospinal fluid and plasma for biomarker discovery. : In this study, we conducted a comprehensive multi-omics analysis of saliva samples ( = 20 mild cognitive impairment (MCI), = 20 Alzheimer's disease and age- and = 40 gender-matched cognitively normal individuals), from the South Australian Neurodegenerative Disease (SAND) cohort, integrating proteomics, metabolomics, and microbiome data with plasma measurements, including pTau181.

Structural insights into the enzymatic breakdown of azomycin-derived antibiotics by 2-nitroimdazole hydrolase (NnhA).

The antibiotic 2-nitroimidazole (2NI) or azomycin, used for treating drug-resistant tuberculosis and imaging tumor hypoxia, requires activation by bacterial nitroreductases for its antibiotic and cytotoxic effect. Mycobacterium sp. JS330 produces 2-nitroimidazole nitrohydrolase (NnhA) that circumvents 2NI activation, conferring 2NI resistance by hydrolysing it to nitrite and imidazol-2-one (IM2O) instead.

Seminal fluid proteins in the Queensland fruit fly: Tissue origins, effects of mating and comparative genomics.

In many insect species, the ability of males to inhibit their mates from remating is an important component of fitness. This ability is also essential for the effective management of insect pests, including tephritid fruit flies, using the Sterile Insect Technique. Here we apply transcriptomics and proteomics to male reproductive tissues before and after mating to characterize components of semen that might mediate remating inhibition in Queensland fruit fly.

[Characteristics, Sources, and Health Risk Changes of Heavy Metal Pollution Carried by PM in Beijing and Evaluation of Policy Effectiveness].

To evaluate the effectiveness of air pollution prevention and control measures in Beijing, this study measured the content of 13 metal elements, including seven heavy metal elements [As, Cd, Co, Cr（Ⅵ）, Ni, Pb, and V], through daily PM sampling （ = 934） in the urban area of Beijing for four years. We analyzed the interannual changes in the concentration levels of various metals and the differences between heating and non-heating seasons, used a positive definite matrix factorization （PMF） model for quantitative source analysis, and used health risk assessment methods to evaluate the health risks of six metals. The results showed that, except for a few metal elements such as Cr（Ⅵ） and Ni, which showed an increase in concentration in individual years, the overall concentration of each element showed a downward trend.

Clinical Diagnostic Significance of Combined Measurement of Lipoprotein(a) and Neck Circumference in Patients with Coronary Heart Disease.

Objective: The study aimed to explore the clinical diagnostic significance of lipoprotein(a) [Lp(a)] and neck circumference (NC) in patients with coronary heart disease (CHD).

Methods: This cross-sectional study was conducted at Chengde Central Hospital from September 2021 to June 2023, enrolling 791 patients with suspected CHD who underwent selective coronary angiography (CAG). Patients were categorized into CHD and non-CHD groups based on the severity of arterial narrowing.

Amorphous-Crystalline Interface Induced Internal Electric Fields for Electrochromic Smart Window.

Balancing optical modulation and response time is crucial for achieving high coloration efficiency in electrochromic materials. Here, internal electric fields are introduced to titanium dioxide nanosheets by constructing abundant amorphous-crystalline interfaces, ensuring large optical modulation while reducing response time and therefore improving coloration efficiency. Aberration-corrected high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) reveals the presence of numerous amorphous-crystalline phase boundaries in titanium dioxide nanosheets.

Decay and Termite Resistance of Wood Modified by High-Temperature Vapour-Phase Acetylation (HTVPA), a Simultaneous Acetylation and Heat Treatment Modification Process.

High-temperature vapour-phase acetylation (HTVPA) is a simultaneous acetylation and heat treatment process for wood modification. This study was the first investigation into the impact of HTVPA treatment on the resistance of wood to biological degradation. In the termite resistance test, untreated wood exhibited a mass loss (ML) of 20.

The complete mitochondrial genome of enigmatic mycoparasitic fungus .

The complete mitochondrial genome of I. Saar, is unveiled in this research for the first time. It covers 76,643 base pairs (bp) and exhibits a guanine-cytosine (GC) content of 23%.

Clinical Value of the Diagonal Earlobe Crease in Patients with Chest Pain for Diagnosing Coronary Heart Disease.

Purpose: To investigate the clinical application value of diagonal earlobe crease (DELC) in patients with chest pain for the diagnosis of coronary heart disease (CHD) and to construct a risk model by multivariate logistic regression.

Patients And Methods: Our trial enrolled prospectively and consecutively 706 chest pain patients with suspected CHD between January 2021 to June 2023 from Chengde Central Hospital. According to coronary angiography results, they were categorized into the CHD (n=457) and non-CHD groups (n=249).

Stress-induced ordering evolution of 1D segmented heteronanostructures and their chemical post-transformations.

Investigations of one-dimensional segmented heteronanostructures (1D-SHs) have recently attracted much attention due to their potentials for applications resulting from their structure and synergistic effects between compositions and interfaces. Unfortunately, developing a simple, versatile and controlled synthetic method to fabricate 1D-SHs is still a challenge. Here we demonstrate a stress-induced axial ordering mechanism to describe the synthesis of 1D-SHs by a general under-stoichiometric reaction strategy.

Manipulating Hetero-Nanowire Films for Flexible and Multifunctional Thermoelectric Devices.

Flexible thermoelectric devices hold significant promise in wearable electronics owing to their capacity for green energy generation, temperature sensing, and comfortable wear. However, the simultaneous achievement of excellent multifunctional sensing and power generation poses a challenge in these devices. Here, ordered tellurium-based hetero-nanowire films are designed for flexible and multifunctional thermoelectric devices by optimizing the Seebeck coefficient and power factor.