Mechanisms of clay mineral-induced targeted deposition and synergistic CO2 sequestration potential in the CCUS-EOR process.

Background: Strongly water-sensitive reservoirs with high clay content face challenges in conventional development due to clay swelling and impeded seepage. CO2 injection shows potential for enhanced oil recovery (EOR) and carbon sequestration; however, the role of clay minerals in regulating CO2-induced asphaltene deposition and sequestration remains unclear.

Methodology: We conducted experiments on clay-oil interactions, nuclear magnetic resonance (NMR), measurements of crude oil properties, and long core water flooding tests to evaluate deposition, reservoir damage, and CO2 sequestration.

Research progress of dosiomics in precision radiotherapy.

Radiotherapy is a conventional method that plays an important role in the comprehensive treatment of tumors. However, it has inevitable side effects that may affect prognosis. Therefore, increasing attention has been paid to radiotherapy-related side effects and prognosis after radiotherapy.

Ta-doped NiFe layered double hydroxide for efficient alkaline water oxidation at ampere-level current with 2000 h durability.

Electrochemical water splitting offers a sustainable strategy for hydrogen production, yet the kinetic sluggishness of the oxygen evolution reaction (OER) due to high activation barriers remains a critical challenge. NiFe layered double hydroxide (NiFe LDH) is a promising OER catalyst in alkaline media, but its performance suffers from limited active site exposure and insufficient durability. Herein, the rational design of a Ta-doped NiFe LDH (NiFeTa LDH) were achieved a facile hydrothermal method.

Ultralong-Lived Excitons in Metallo-Quinoline-Incorporated Covalent Organic Frameworks Promote Photoreductive Cross-Coupling.

Designing long-lived excitons in photocatalysts is crucial for efficient charge separation. However, most of the current organic photocatalysts are characterized by a relatively short exciton lifetime within the range of picoseconds due to localized excitons with large binding energies. Herein, we report the design of ultralong-lived excitons with a lifetime exceeding 8000 ps by constructing metallo-quinoline-incorporated covalent organic frameworks (COFs).

Development of a validated and sensitive ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method to simultaneous determination of crizotinib, alectinib and lorlatinib in human plasma.

Crizotinib, alectinib, and lorlatinib are tyrosine kinase inhibitors used sequentially in non-small cell lung cancer (NSCLC) therapy. Therapeutic drug monitoring (TDM) is valuable during sequential treatment, enabling simultaneous quantification. Consequently, an analytical method capable of multiplexing these three compounds into a single assay is highly applicable for routine TDM.

Visualizing energy transfer between redox-active colloids.

Redox-active colloids (RACs) represent a novel class of energy carriers that exchange electrical energy upon contact. Understanding contact-mediated electron transfer dynamics in RACs offers insights into physical contact events in colloidal suspensions and enables quantification of electrical energy transport in nonconjugated polymers. Redox-based electron transport was directly observed in monolayers of micron-sized RACs containing ethyl-viologen side groups via fluorescence microscopy through an unexpected nonlinear electrofluorochromism that is quantitatively coupled to the redox state of the colloid.

The comparison of the prognostic value of different inflammation-related indicators in patients with oral squamous cell carcinoma.

Background: This study aimed to determine the prognostic significance of inflammation markers for patients with oral squamous cell carcinoma (OSCC) and sought to analyze the reasons behind it and its value for clinical guidance.

Methods: This study enrolled 624 patients with OSCC who were surgically treated in our hospital. Clinical baseline data and peripheral blood routine/biochemical parameters were collected within 1 week before surgery.

Efficacy and Safety Analysis of Transarterial Chemoembolization Combined with Sintilimab Plus Bevacizumab Biosimilar in the Treatment of Unresectable Hepatocellular Carcinoma.

Background: Transarterial chemoembolization (TACE) remains a cornerstone for unresectable hepatocellular carcinoma (uHCC) but is limited by tumor progression. Combining TACE with systemic therapies may enhance efficacy. Notably, sintilimab combined with bevacizumab biosimilar has shown synergistic effects in tumor control and has been incorporated into the first-line treatment regimen in China.

(Polygonaceae: Persicarieae), a Distinct New Species From Xizang, Southwestern China.

, a distinctive new species discovered in Medog County, southeastern Xizang, China, is here described and illustrated. The generic placement of this species was validated through integrated morphological and palynological observations, as well as molecular phylogenetic analyses using three cpDNA markers (, , and ). Within , is most closely related to but differs significantly in growth habit, leaf shape, inflorescence structure, and achene micromorphology.

A near-infrared responsive photocaged amplified DNA nanodevice for precise and sensitive microRNA imaging.

MicroRNAs (miRNAs) play a critical role in early cancer detection, but traditional DNA probes are limited by the low abundance of miRNAs and their "always effective" property. Herein, we construct a photocaged amplified DNA nanodevice (PAD) by attaching DNA probes to upconversion nanoparticles (UCs). Upon remote near-infrared (NIR) light stimulation, the photocleavable DNA probes are activated by emitted UV light, and subsequently triggered by target miRNA.

Quasi-Homogeneous Photocatalytic C─H Functionalization Enabled by Donor-Acceptor Microporous Polymer Aerogels Featuring Ultralong-Lived and Long-Range Excitons.

Simultaneous promotion of charge and mass transportation between catalytic centers and reactants is crucial for photocatalysis but remains a substantial challenge on account of the widespread use of homogeneous or heterogeneous photocatalysts that suffer from sluggish reactant-diffusion kinetics or interfacial electron-transport resistance, respectively. Herein, we demonstrate the construction of conjugated microporous polymer aerogels as available quasi-homogeneous photocatalysts by integrating structural designability, which allows for the incorporation of electron-acceptor building blocks featuring ultralong-lived excitons as high-concentration local catalytic centers, and hierarchically porous gel networks that wrap solvent and reactants to provide a "single" reaction phase without interfacial resistance. A total of 18 samples of C─H functionalization reactions underpinned by four different mechanisms were screened to showcase the general applicability of the obtained aerogel photocatalysts, which achieved remarkable conversion efficiencies, gram-scale productivities, and recyclability.

Development of a novel rabbit model of angular kyphosis and characterization of its neuropathological features.

Background: Angular kyphosis, often resulting from congenital anomalies, trauma, infections, or tumors, can cause severe spinal cord compression, ischemia, and neurological dysfunction. Due to its sharp curvature and complexity, angular kyphosis remains challenging to treat surgically. This study aimed to establish a rabbit model to mimic the progression of angular kyphosis and its neurological consequences.

Local abaloparatide administration promotes in situ alveolar bone augmentation via FAK-mediated periosteal osteogenesis.

Insufficient alveolar bone thickness increases the risk of periodontal dehiscence and fenestration, especially in orthodontic tooth movement. Abaloparatide (ABL), a synthetic analog of human PTHrP (1-34) and a clinical medication for treating osteoporosis, has recently demonstrated its potential in enhancing craniofacial bone formation. Herein, we show that intraoral submucosal injection of ABL, when combined with mechanical force, promotes in situ alveolar bone thickening.

Acute cutaneous adverse drug reactions in hepatocellular carcinoma patients undergoing combined targeted and immunotherapy: unraveling the impact of dosage and interval.

Background: Combination of targeted therapy and immune checkpoint inhibitors (ICIs) is a leading approach in the treatment of advanced hepatocellular carcinoma (HCC). However, an increased incidence of skin rashes poses a clinical challenge. Understanding the acute cutaneous adverse drug reactions (CADRs) during the early stage of the combination treatment is crucial.

Carbon-Degrading Gene Resistance Contributes to Microbial Thermal Adaptation of Soil Carbon Decomposition.

The thermal adaptation of the microbial community can potentially mitigate the positive feedback between soil carbon loss and climate change. However, the mechanistic basis of this process remains unclear, particularly the link between functional genes and microbial metabolic physiology in regulating the thermal response of soil carbon decomposition. While most experimental warming studies have examined elevated mean temperatures, the magnitude of temperature fluctuations is also increasing under climate change and may impose distinct ecological effects on microbial processes.

How electronic health literacy influences physical activity behaviour among university students: A moderated mediation model.

Purpose: This study examines how eHealth literacy influences exercise behaviour among university students through a moderated mediation model. Specifically, peer relationships are positioned as mediators, while sleep quality moderates the effect of eHealth literacy on exercise behaviour among university students. The study explores the intricate interactions involved and elucidates how eHealth literacy affects exercise behaviour through multiple dimensions.

Study on deformation law of coal pore mechanism characteristics under peak cluster landform.

In order to reveal the change rule of coal pore structure under the peak cluster landform, coal samples were taken from nine different mountain heights based on the vertical variability of the landform, and the pore structure of the coal samples was tested using a combination of high-pressure mercuric pressure method and low-temperature nitrogen adsorption experiments. The results show that compared with the traditional coal reservoir, the pore structure of coal under the peak cluster landform, such as pore content, specific surface area and pore volume, changes with the change of vertical principal stress in a multi-peak state. The variations in the maximum and minimum values of vertical principal stress at each peak level are 1.

Trust the Machine or Trust Yourself: How AI Usage Reshapes Employee Self-Efficacy and Willingness to Take Risks.

As artificial intelligence (AI) technology becomes increasingly widespread in organizations, its impact on individual employees' psychology and behavior has garnered growing attention. Existing research primarily focuses on AI's effects on organizational performance and job design, with limited exploration of its mechanisms influencing individual employees, particularly in the critical area of risk-taking behavior, which is essential to organizational innovation. This research develops a moderated mediation model grounded in social cognitive theory (SCT) to explore how AI usage affects the willingness to take risks.

A calcium-decoding module translates volatile DMNT into jasmonic acid-mediated herbivore resistance in Camellia sinensis.

Plants employ sophisticated volatile-mediated signaling mechanisms to defend against herbivore attacks; however, the molecular pathways underlying these processes remain poorly understood. Herein, we unveil the molecular mechanism by which the herbivore-induced volatile (E)-4,8-dimethyl-1,3,7-nonatriene (DMNT) activates jasmonic acid (JA) biosynthesis in tea plants (Camellia sinensis). We demonstrate that DMNT triggers early signaling events in tea plants, characterized by a rapid influx of Ca2+ in mesophyll cells, which subsequently initiates a signaling cascade involving the CsCAMTA3 (calmodulin-binding transcription activator, CAMTA).

Minimizing Photovoltage Loss for Efficient p-i-n Perovskite Solar Cells via a Dual-Site Anchoring Bridge.

Perovskite solar cells (PSCs) suffer from severe nonradiative recombination-induced photovoltage loss, limiting the device overall performance. To address this key issue, an efficient strategy via a dual-site anchoring bridge is developed to engineer the heterointerface between perovskite and PCBM electron transport layer. The resulting reinforced and homogeneous passivation by forming strong dual-site P─O─Pb covalent bonds, effectively decreases perovskite surface defect density.

Robust p-type ohmic contact in ZrI/Dirac semi-metal van der Waals heterostructures.

For high-performance nanoelectronic devices, choosing the appropriate and reliable electrode contact material is of vital importance. Through first-principles calculations, we have systematically investigated the geometric structural stability and electronic contact properties between monolayer 2H-phase ZrI and two-dimensional Dirac semi-metals. The results indicate that ZrI/semi-metal heterostructures are highly stable.

A Multifunctional Molecular Probe for Multimodal Imaging-Guided Potent Photothermal/Photodynamic Therapy of Endometriosis.

Multifunctional small-molecule theranostic agents hold significant clinical potential for non-invasive endometriosis (EMS) management. Current EMS treatment faces challenges due to imprecise lesion localization and therapy-associated side effects. Herein, an integrated theranostic probe, cRGDyK-ICG-Lys-DTPA@Gd (cRGD-ILD), designed for concurrent precise lesion localization and targeted phototherapy in EMS, is developed.

Eight previously undescribed flavonoids and four previously undescribed bibenzyls from Macaranga kurzii and their potential antiviral activities.

Eight previously undescribed flavonoids, named makurziis A-H (1-8), four previously undescribed bibenzyls, named mayankurziis A-D (9-12), as well as nine known compounds were isolated from the ethyl acetate extract of dried stems and leaves of Macaranga kurzii. Their structures were thoroughly elucidated through detailed spectroscopic analysis and comparison with existing literature data. Additionally, the structures of compounds 3 and 7 were further confirmed by single-crystal X-ray diffraction analysis.

Visible light-driven activation of peroxymonosulfate by tubular O, S co-doped g-CN for efficient aflatoxin B degradation in edible oils.

Aflatoxin B (AFB) contamination in edible oils poses severe food safety threats, with traditional photocatalysis hindered by insufficient reactive oxygen species (ROS) precursors in lipid matrices. This study integrates tubular O, S co-doped g-CN (OSTCN) photocatalysis into edible oil water-washing, in the simulated dual-phase systems, OSTCN activates peroxymonosulfate (PMS) under visible light to generate ROS, achieving complete degradation of oil-phase migrated parent AFB within 120 min while maintaining oil quality within acceptable thresholds. Combined evidence reveals that the tubular structure enhances light harvesting, while O, S co-doping creates electron donor-acceptor sites that strengthen PMS adsorption and electron transfer, reducing activation barriers and conferring 6.

Bidirectional Beta-Tuned Diffusion Model.

Diffusion models have gained significant attention in the field of generative modeling due to their capability to produce high-quality samples. However, recent studies show that applying a uniform treatment to all distributions during the training of diffusion models is sub-optimal. In this paper, we present a comprehensive theoretical analysis of the forward process in diffusion models.