Trophic transfer of CeO nanoparticles from clamworm to juvenile turbot and related changes in fish flesh quality.

Engineered nanoparticles (ENPs) accumulate in marine sediments and exhibit adverse effects on benthic organisms. However, the effect of ENPs on marine benthic food chains is largely unknown. Herein, we investigated the trophic transfer and transformation of CeO ENPs within a simulated marine benthic food chain from clamworm () to turbot (), as well as their effects on fish flesh quality.

Adaptive or maladaptive music-listening coping strategy: How does neuroticism use music after experiencing a romantic relationship breakup?

Romantic relationship breakups are common experiences among young people and are associated with negative emotions that can jeopardize psychological well-being. Additionally, those with higher neuroticism may have greater emotional sensitivity towards the impact of music, as they tend to exhibit more negative and unstable emotional traits. As a result, they may be more inclined to control emotions by using music as a coping strategy.

Soyasaponin and vertical microbial transmission: Maternal effect on the intestinal development and health of early chicks.

Multiple factors, including genetics, nutrition, and health, influence the vertical transmission of microbiota from mothers to their offspring. Recent studies have shown that avian microbiota can be passed to the next generation via the eggshell and egg albumen. However, it remains unclear whether these microbial communities are regulated by nutrition and how they are associated with the host genotype.

Schisandra chinensis mixture attenuates diabetic kidney disease via VDAC1/Grp75/IPR-mediated MAMs stabilization and apoptosis-autophagy regulation.

Background: Diabetic kidney disease (DKD) is a major cause of end-stage renal disease, with mitochondrial dysfunction-mediated tubular injury implicated in its pathogenesis. Mitochondria-associated membranes (MAMs) coordinate apoptosis and autophagy in diabetic tubular injury. While Schisandra chinensis Mixture (SM) shows renoprotective effects, its mechanism in counteracting hyperglycemia-induced tubular cell death and fibrosis via MAMs integrity remains unclear.

Correction: Association between genetically proxied glucosamine and risk of cancer and non-neoplastic disease: a mendelian randomization study.

[This corrects the article DOI: 10.3389/fgene.2024.

Antibody-free quantification of serum infliximab using LC-MS/MS.

Infliximab (IFX) is the first biologic to be approved to treat inflammatory bowel disease (IBD). Serum IFX concentrations can be correlated with the clinical prognosis of IBD. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is an alternative to clinical immunoassays owing to its higher selectivity and sensitivity.

Polyinfection secondary to exogenous lipoid pneumonia caused by aspiration of paraffin oil: a Case Report.

Background: Exogenous lipoid pneumonia is a rare condition caused by the aspiration of lipid-containing substances. Its diagnosis can be challenging due to non-specific respiratory symptoms and imaging findings. Complications, such as secondary infections, may exacerbate the clinical course, particularly in immunocompromised or elderly patients.

Design and development of an aptamer targeting C-type lectin-like molecule-1 as a biomarker for acute myeloid leukemia: a SELEX approach.

Acute myeloid leukemia (AML), a hematologic malignancy, is an important public health issue. It is a result of the abnormal proliferation of immature myeloid cells. Despite advancements in diagnostic procedures, the early identification of AML remains a significant clinical challenge, marking a distinctive niche for newer theranostic approaches to ameliorate diagnosis and treatment.

Nitrogen-Centered Organic Salts Enable Stable Lithium-Ion Supply for High-Energy-Density Batteries.

Compensating lithium (Li) ions for high-energy-density batteries is essential, as the anodes such as silicon-based materials present up to 20% Li-ion loss in the initial cycle. Current Li-ion supply molecules present side reactions with battery components and lead to undesirable gas generation due to the intrinsic electrochemical mechanism. To address this, we report the design of a nitrogen (N)-centered organic salt, lithium-benzimidazol-2-one (LiNCHO), capable of supplying Li-ions without damaging the battery chemical environment and effectively protecting the Ni-rich cathode surface.

Augmented recruitment of host Grb2 by Helicobacter pylori tyrosine phosphorylated CagA EPIYA-D motif promotes cellular oncogenic transformation.

CagA, one of the key virulence factors of Helicobacter pylori, plays a significant role in H. pylori-associated gastric cancer by actively participating in neoplastic transformation. Among CagA variants, East Asian type CagA (CagA) bearing the EPIYA-D motif exhibits a higher risk than the Western-type (CagA) with EPIYA-C motifs.

Serum lipidomics analysis reveals yolk sac absorption differences in newly hatched chicks.

The yolk sac provides nutrients to a newly hatched chick with maternal nutrient substances including large amounts of lipids. Higher resorption of the yolk sac is generally considered positive for chick development. However, it is hard to determine yolk sac absorption differences among living chicks with similar body weight for assessing chick quality.

3D-printed model combined with the Ilizarov technique in the treatment of genu varum in children with hypophosphatemic rickets.

Introduction: Genu varum in children with hypophosphatemic rickets are complex and always occur on multiple planes, which are difficult to correct. This present study is aimed to retrospectively explore the feasibility and efficacy of 3D-printed model combined with the Ilizarov technique in the treatment of genu varum in children with hypophosphatemic rickets.

Methods: From March 2010 to July 2020, 7 hypophosphatemic rickets patients with genu varum were retrospectively analyzed in our hospital.

Formic acid impairs α-synuclein seeding activity in human and mouse brains.

Unlabelled: α-Synuclein (α-syn) is an abundant monomeric protein that can aggregate into fibrils and form neuropathological inclusions in the brains of patients with synucleinopathies. New evidence suggests that the mouse-human transmission barrier of α-syn is lower than previously reported, emphasizing the need for improved biosafety procedures when working with α-syn aggregates. Histopathology of α-syn-infected brain represents a significant potential source of occupational exposure, and current methods for tissue fixation do not inactivate the ability of pathologic α-syn to seed the conversion of endogenous, monomeric α-syn into fibrils.

CMSCNet: a context based lightweight musculoskeletal ultrasound image segmentation method.

Background: Musculoskeletal ultrasound (MSUS) is a non-invasive and non-intrusive method for examining muscles and bones. Therefore, MSUS image analysis plays a crucial role in the assessment and early detection of musculoskeletal disorders However, due to the complexity of noise in MSUS images, analyzing and interpreting these images is a tedious and time-consuming process. Currently, ultrasound devices still rely on manual methods to analyze structural parameters such as muscle thickness, penniform angle, and fascicle length.

Functional analysis of CBL-interacting protein kinases 15 (StCIPK15) in response to salt and heat stress in potato (Solanum tuberosum L.).

Potato (Solanum tuberosum L.), a staple crop, is highly susceptible to environmental stressors such as high salinity and elevated temperatures. Calcineurin B-like (CBL) proteins and CBL-interacting protein kinases (CIPKs) form sensor-response complexes that regulate plant growth, development, differentiation, and stress responses.

Laccase immobilized on amino acid ionic liquid-modified magnetic lignin nanoparticles and its degradation of 2,4-dichlorophenol.

Immobilized laccase demonstrates significant potential for 2,4-dichlorophenol (2,4-DCP) degradation in environmental remediation applications. However, challenges persist in optimizing carrier materials for enzyme immobilization. In this study, a magnetic lignin-based nanocomposite (FeO-SL) was synthesized and further functionalized with amino acid-derived ionic liquids (AAILs).

Enrichment of anthropogenic organic matter and acetoclastic pathway dominates ebullition CH production in urban river.

Methane (CH) ebullition emission is recognized as an important contributor to CH fluxes in urban rivers, and understanding ebullition CH production and emission is important to accurately identify the global river carbon budget. However, the current generation pathways of ebullition CH in different types of rivers are still not fully understood. In this study, the isotope technique was used to investigate the production pathways of ebullition CH in different types of rivers through a combination of field investigation and incubation experiment in Shanghai rivers networks to explore the regulating factors of ebullition CH emission.

SIRT5 is associated with asthenozoospermia and regulates GC‑2 spd cell proliferation and apoptosis.

Infertility is a multifactorial condition that affects ~7% of the male population. The mechanism of male infertility primarily involves intrinsic and environmental factors, of which genetic defects are key for its occurrence. Sirtuin 5 (SIRT5) is primarily localized in mitochondria and associated with male reproduction.

Trauma, complex PTSD, and somatoform dissociation among disadvantaged parents in a community center: Prevalence and relationships with parenting and children's behavioral problems.

Background: Although the health effects of trauma have been increasingly recognized, much less is known about the intergenerational effects of trauma and its outcomes.

Aims: This study examined trauma and trauma-related mental health problems among socio-economically disadvantaged parents.

Methods: We recruited parents in disadvantaged housing and living conditions from a community development center in Hong Kong (response rate = 74.

Neural signaling contributes to heart formation and growth in the invertebrate chordate, .

Neurons contribute to the complex interplay of signals that mediate heart development and homeostasis. Although a limited set of studies suggest that neuronal peptides impact vertebrate heart growth, the specific contributions of these peptides to cardiomyocyte progenitor differentiation or proliferation have not been elucidated. Here we show that the neuropeptide tachykinin along with canonical Wnt signaling regulate cardiomyocyte progenitor proliferation in the chordate model .

Parents' experience in pediatric Tuina treatment program for congenital muscular torticollis in infants and children: qualitative findings from individual interviews.

Background: Pediatric tuina treatment program is an intervention of traditional Chinese medicine that involves specific manual techniques applied to the bodies of infants and children to promote health and treat conditions such as congenital muscular torticollis (CMT). This study was conducted to understand facilitators, barriers, and influencing factors in the implementation of pediatric tuina treatment program based on parents' experiences.

Methods: Semi-structured individual interviews were conducted with parents' experience in Shandong province, China.

Routine psychological problems screening in hospitalized inflammatory bowel diseases and its effect for progression-free survival from disease worsening.

Background: To examine the progression-free survival from disease worsening after the implementation of routine screening for psychological problems in hospitalized patients with inflammatory bowel diseases (IBDs) during a long-term follow-up.

Methods: The retrospective cohort study enrolled 1265 patients with active IBDs. Their records were stratified into screening cohort (n = 827), receiving screening for psychological problems within 48 h after admission, and a 2:1 propensity score matching was utilized to match cases without screening as controls (n = 438).

Deciphering the role of signal regulatory protein α in immunotherapy for solid tumors.

Therapies targeting immune checkpoints like programmed death receptor-1 and programmed death ligand-1 have demonstrated remarkable effectiveness in combating cancer. However, a subset of patients fails to respond to these therapies, underscoring the complexity of tumor immune evasion mechanisms. Exploring innovative immune regulatory targets represents a crucial research priority in this field.

Robust imaging flow cytometer based on in-silico optofluidic time-stretch imaging with assistance of optical phase.

Imaging flow cytometry is a widely used technique for high-throughput, label-free single-cell analysis. However, its effectiveness is often compromised by experimental perturbations, such as random defocusing and off-axis light coupling, which degrade image quality and hinder reliable analysis. In this study, we present a robust imaging flow cytometer based on in-silico optofluidic time-stretch imaging with the assistance of optical phase.