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Background: Musculoskeletal ultrasound (MSUS) is a non-invasive and non-intrusive method for examining muscles and bones. Therefore, MSUS image analysis plays a crucial role in the assessment and early detection of musculoskeletal disorders However, due to the complexity of noise in MSUS images, analyzing and interpreting these images is a tedious and time-consuming process. Currently, ultrasound devices still rely on manual methods to analyze structural parameters such as muscle thickness, penniform angle, and fascicle length. While recent advancements in deep learning have shown promise in automating image segmentation tasks, existing methods often require extensive computational resources and may not be suitable for real-time applications. There remains a need for lightweight and efficient models that can achieve high accuracy while reducing computational load. This study aims to address this gap by proposing a context-based lightweight deep-learning framework for the automatic segmentation of MSUS images.
Methods: We propose a context-based lightweight deep learning framework for the automatic segmentation of MSUS images, aiming to make the segmented images as close as possible to those manually annotated by professional doctors. This method is based on the U-Net architecture, with multi-layer perception modules added to the encoder and decoder to reduce the number of parameters and improve computational efficiency. Additionally, a dense atrous convolution module is used to extract contextual features from the images, improving segmentation accuracy, and a restructured convolution module for spatial and channel dimensions is employed to reduce the extraction of redundant features during the segmentation task. We applied our method to a publicly available leg muscle dataset to extract and analyze the morphological features of the penniform muscle and conducted ablation experiments.
Results: The results showed that the accuracy of our algorithm was 98.7%, the same as the U-Net architecture, but with only one-tenth of the parameters. The average intersection over union (IoU) also reached 0.7227. Our network can capture more details of the muscle aponeurosis and effectively focuses on the junctions between the aponeurosis and muscle fibers, showing minimal differences from the ground truth and achieving very high accuracy.
Conclusions: This method can automatically, quickly, and accurately extract the morphological features of penniform muscles, providing a basis for improving the accuracy of muscle pathology assessment, the precision of interventional therapy, and the scientific rigor of rehabilitation treatment.
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http://dx.doi.org/10.21037/qims-2024-2523 | DOI Listing |
Eur Radiol Exp
September 2025
Department of Orthopaedics and Trauma Surgery, Orthopaedic Oncology, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Munich, Germany.
Computed tomography (CT) and magnetic resonance imaging (MRI) are commonly used to assess femoral and tibial torsion. While CT offers high spatial resolution, it involves ionizing radiation. MRI avoids radiation but requires multiple sequences and extended acquisition time.
View Article and Find Full Text PDFJMIR Med Inform
September 2025
Department of Radiology, Air Force Medical Center, Air Force Medical University, Fucheng Road 30, Haidian District, Beijing, CN.
Background: Lateral malleolar avulsion fracture (LMAF) and subfibular ossicle (SFO) are distinct entities that both present as small bone fragments near the lateral malleolus on imaging, yet require different treatment strategies. Clinical and radiological differentiation is challenging, which can impede timely and precise management. On imaging, magnetic resonance imaging (MRI) is the diagnostic gold standard for differentiating LMAF from SFO, whereas radiological differentiation on computed tomography (CT) alone is challenging in routine practice.
View Article and Find Full Text PDFInt J Nanomedicine
September 2025
Department of Orthopedics, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.
Peptide-based fluorescent probes have found widespread applications in biomedical research, including bio-imaging, disease diagnosis, drug discovery, and image-guided surgery. Their favorable properties-such as small molecular size, low toxicity, minimal immunogenicity, and high targeting specificity-have contributed to their growing utility in both basic research and translational medicine. This review provides a comprehensive overview of recent advances in peptide-based fluorescent probes, emphasizing design strategies, biological targets, and diverse functional applications.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Orthopaedic Surgery, Kobe Red Cross Hospital, Hyogo, Japan.
This study aims to clarify the dynamic changes in the cervical lordotic angle (CLA) during normal swallowing using an automated motion analysis method. Physiological cervical lordosis is crucial for spinal alignment and musculoskeletal function. While previous studies have noted the relevance of cervical curvature in clinical contexts, its dynamic modulation during swallowing has not been well studied.
View Article and Find Full Text PDFRMD Open
September 2025
Department of Rheumatology and Department of Internal Medicine, Ghent University Hospital, Unit for Molecular Immunology and Inflammation, Flemish Institute for Biotechnology, Inflammation Research Center, University of Ghent, Ghent, Belgium.
Objectives: To evaluate whether patients with systemic lupus erythematosus (SLE) have different nailfold videocapillaroscopy (NVC) findings compared with healthy controls (HCs) and whether there is an association between NVC abnormalities and disease activity, clinical and/or laboratory features in SLE.
Methods: This is an observational, multicentre, international, matched case-control study. 381 subjects (203 patients with SLE and 178 HCs) were enrolled from 16 centres in 10 countries.