Sleep quality mediates the association between tea consumption and duration of COVID-19-related symptoms in middle-aged and elderly adults (aged 50 and above).

Objectives: The association between tea consumption and the duration of COVID-19-related symptoms remains inconclusive. This cross-sectional study investigates the potential mediating role of sleep quality in this association. The association between tea consumption and the duration of COVID-19-related symptoms remains inconclusive.

Synchronous Phase Transformation for Efficient Wide-Bandgap Perovskite Photovoltaics.

Mixed-halogen wide-bandgap (WBG) perovskite materials are employed in tandem solar cells (TSCs) due to their continuous tunability of bandgap. However, inhomogeneous halogen phases are often observed in bromine-rich perovskite films, which restricts the performance of WBG perovskite solar cells (PSCs) and TSCs. Here, homogeneous halogen-phase perovskite is proposed to form film by a synchronous halogen-phase transformation strategy.

Three-Dimensional-Printed Ordered Bredigite Scaffolds with Dual Bioactivities Promote Osteochondral Regeneration.

Osteochondral tissues have limited self-healing abilities, making it challenging to achieve complete healing following injury. Osteochondral defects present significant clinical challenges. Bredigite (BRT, CaMgSiO) bioceramic scaffolds exhibit excellent physicochemical properties, biocompatibility, osteoinductivity, and osteoconductivity, making them promising candidates for osteochondral repair and regeneration.

A novel technique for submucosal tumors in the esophagus: mucosal zipper endoscopic resection.

The mucosal zipper endoscopic resection (MZER) technique was developed as a novel approach for treating esophageal submucosal tumors (SMTs). This study aims to introduce the MZER technique and evaluate its feasibility.This retrospective study included 24 patients who underwent MZER between January 2022 and January 2024.

Promoting Phase Transition in Quasi-2D Perovskites For High-Performance Pure-Red LEDs.

Layered quasi-two-dimensional (quasi-2D) halide perovskites have emerged as a promising platform for high-efficiency electroluminescence. Narrowing the multi-quantum well distribution and eliminating wide-bandgap 2D phases are crucial for achieving a flat energy landscape, minimizing energy loss, and ensuring high-color-purity emission. Here, it is demonstrated that solution-processed quasi-2D perovskite films with broad component distributions arise from an incomplete kinetic transition from low-n (n, quantum well thickness) to high-n phases.

Exogenous TSG-6 treatment alleviates DSS-induced colitis in mice by modulating Pou2f3 and promoting tuft cells differentiation.

Background: Whereas intestinal epithelial barrier dysfunction is implicated in inflammatory bowel disease (IBD), the underlying mechanisms remain elusive. Tumor necrosis factor α stimulated gene 6 (TSG-6) is a secretory protein with anti-inflammatory properties. Our previous research demonstrated TSG-6 can relieve intestinal inflammation and mucosal damage.

Photoreceptor metabolic window unveils eye-body interactions.

Photoreceptors are specialized neurons at the core of the retina's functionality, with optical accessibility and exceptional sensitivity to systemic metabolic stresses. Here we show the ability of risk-free, in vivo photoreceptor assessment as a window into systemic health and identify shared metabolic underpinnings of photoreceptor degeneration and multisystem health outcomes. A thinner photoreceptor layer thickness is significantly associated with an increased risk of future mortality and 13 multisystem diseases, while systematic analyses of circulating metabolomics enable the identification of 109 photoreceptor-related metabolites, which in turn elevate or reduce the risk of these health outcomes.

Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults.

Purpose: To investigate the 10-year changes in visual function and incidence of visual impairment (VI) in highly myopic eyes.

Methods: This longitudinal study enrolled highly myopic individuals who were followed up for 10 years. All participants underwent detailed ophthalmic examinations at baseline and follow-up visits.

Safety of repeated low-level red-light therapy for myopia: A systematic review.

Purpose: Establishing the safety profile of repeated low-level red-light (RLRL) therapy is necessary prior to its widespread clinical implementation.

Methods: We conducted a systematic review (International Prospective Register of Systematic Reviews, CRD42024516676) of articles across seven databases from inception through February 10, 2024, with keywords related to myopia and RLRL therapy. Pooled safety outcomes and risk-to-benefit ratios were reported, and incidence of side effects was compared with other antimyopia interventions.

A new generative method for multi-focus image fusion of underwater micro bubbles.

The optical detection methodology stands as a predominant approach for detecting underwater bubbles. Nonetheless, owing to poor underwater imaging conditions, the acquired image depth of field proves inadequate, posing significant challenges for the study and identification of underwater micro bubbles. In this investigation, we present a multi-focus image fusion model tailored for underwater micro bubbles, grounded in the Denoising Diffusion Probabilistic Model.

Metabolomic signature of retinal ageing, polygenetic susceptibility, and major health outcomes.

Background/aims: To identify the metabolic underpinnings of retinal aging and examine how it is related to mortality and morbidity of common diseases.

Methods: The retinal age gap has been established as essential aging indicator for mortality and systemic health. We applied neural network to train the retinal age gap among the participants in UK Biobank and used nuclear magnetic resonance (NMR) to profile plasma metabolites.

Efficient wide-bandgap perovskite photovoltaics with homogeneous halogen-phase distribution.

Wide-bandgap (WBG) perovskite solar cells (PSCs) are employed as top cells of tandem cells to break through the theoretical limits of single-junction photovoltaic devices. However, WBG PSCs exhibit severe open-circuit voltage (V) loss with increasing bromine content. Herein, inhomogeneous halogen-phase distribution is pointed out to be the reason, which hinders efficient extraction of carriers.

Initial Retinal Nerve Fiber Layer Loss and Risk of Diabetic Retinopathy Over a Four-Year Period.

Purpose: The purpose of this study was to investigate whether the rapid rate of peripapillary retinal nerve fiber layer (pRNFL) thinning in short-term is associated with the future risk of developing diabetic retinopathy (DR).

Methods: This prospective cohort study utilized 4-year follow-up data from the Guangzhou Diabetic Eye Study. The pRNFL thickness was measured by optical coherence tomography (OCT).

Chemical Synergic Stabilization of High Br-Content Mixed-Halide Wide-Bandgap Perovskites for Durable Multi-Terminal Tandem Solar Cells with Minimized Pb Leakage.

High Br-content lead mixed-halide perovskites with wide-bandgap (WBG) of 1.6-2.0 eV have showcased vast potential to be used in tandem solar cells.

Trajectories of choriocapillaris perfusion in healthy individuals and patients with diabetes mellitus: a prospective cohort study.

Purpose: To evaluate the longitudinal rate of choriocapillaris flow deficits (CFD) in healthy participants and patients with diabetes mellitus.

Methods: This prospective cohort study included healthy individuals and diabetic patients without diabetic retinopathy (non-DR) or with mild-to-moderate non-proliferative DR (NPDR). The swept-source optical coherence tomography angiography (OCTA) was adopted for quantifying CFD annually, and linear mixed models were used to analyse the CFD change and its 95% CI overtime.

Long-Term Prediction and Risk Factors for Incident Visual Field Defect in Nonpathologic High Myopia.

Purpose: To investigate the long-term patterns and risk factors of visual field defect (VFD) development in nonpathologic high myopia (HM) over an 8-year follow-up.

Methods: This was an observational cohort study. The VFD classification adhered to the Glaucoma Suspects with High Myopia Study Group.

Evaluation of the prognosis in patients with small-cell lung cancer treated by chemotherapy using tumor shrinkage rate-based radiomics.

Background: Small-cell lung cancer (SCLC) is a leading cause of cancer-related death. However, the prognostic value of the tumor shrinkage rate (TSR) after chemotherapy for SCLC is still unknown.

Methods: We performed a retrospective analysis of 235 patients with SCLC.

Blade-Coating (100)-Oriented α-FAPbI Perovskite Films via Crystal Surface Energy Regulation for Efficient and Stable Inverted Perovskite Photovoltaics.

Photoactive black-phase formamidinium lead triiodide (α-FAPbI) perovskite has dominated the prevailing high-performance perovskite solar cells (PSCs), normally for those spin-coated, conventional n-i-p structured devices. Unfortunately, α-FAPbI has not been made full use of its advantages in inverted p-i-n structured PSCs fabricated via blade-coating techniques owing to uncontrollable crystallization kinetics and complicated phase evolution of FAPbI perovskites during film formation. Herein, a customized crystal surface energy regulation strategy has been innovatively developed by incorporating 0.

Plasma Metabolomics Identifies Key Metabolites and Improves Prediction of Diabetic Retinopathy: Development and Validation across Multinational Cohorts.

Purpose: To identify longitudinal metabolomic fingerprints of diabetic retinopathy (DR) and to evaluate their usefulness in predicting DR development and progression.

Design: Multicenter, multiethnic cohort study.

Participants: This study included 17 675 participants from the UK Biobank (UKB) who had baseline prediabetes or diabetes, identified in accordance with the 2021 American Diabetes Association guidelines, and were free of baseline DR and an additional 638 participants with type 2 diabetes mellitus from the Guangzhou Diabetic Eye Study (GDES) for external validation.

Handgrip strength and risks of diabetic vascular complications: Evidence from Guangzhou Diabetic Eye Study and UK cohorts.

Purpose: The purpose is to investigate the association between handgrip strength (HGS) and the risk of future diabetic complications in multicountry cohorts.

Methods: The association between HGS and diabetic complications was evaluated using cox models among 84 453 patients with pre-diabetes and diabetes from the UK Biobank with a 12-year follow-up. The association between HGS and longitudinal microcirculatory damage rates was assessed among 819 patients with diabetes from the Guangzhou Diabetic Eye Study (GDES) with a 3-year follow-up.

Improvement of Photovoltaic Performance of Perovskite Solar Cells by Synergistic Modulation of SnO and Perovskite via Interfacial Modification.

In the past decade, perovskite solar cell (PSC) photoelectric conversion efficiency has advanced significantly, and tin dioxide (SnO) has been extensively used as the electron transport layer (ETL). Due to its high electron mobility, strong chemical stability, energy level matching with perovskite, and easy low-temperature fabrication, SnO is one of the most effective ETL materials. However, the SnO material as an ETL has its limitations.

Laser forward and backward scattering characteristics and experimental study of bubbles in ship wake.

The detection and tracking of ships can be realized by using the laser forward and backward scattering characteristics of ship wake bubbles. In this paper, the detection ability of two kinds of scattering to wake bubbles is studied. Based on the distribution characteristics of ship wake and bubble targets, typical bubble targets are selected to study from both micro and macro aspects.

Strain Regulation of Mixed-Halide Perovskites Enables High-Performance Wide-Bandgap Photovoltaics.

Wide-bandgap mixed-halogen perovskite materials are widely used as top cells in tandem solar cells. However, serious open-circuit voltage (V) loss restricts the power conversion efficiency (PCE) of wide-bandgap perovskite solar cells (PSCs). Herein, it is shown that the resulting methylammonium vacancies induce lattice distortion in methylammonium chloride-assisted perovskite film, resulting in an inhomogeneous halogen distribution and low V.