Visible-light photoredox catalysis for vinyl sulfone construction sulfoxonium ylide alkynylation.

Herein, a visible-light-driven synthesis of 1,4-dicarbonyl vinyl sulfones sulfoxonium ylide homocoupling forming CC bonds, followed by sulfonyl hydrazide alkenylation is disclosed. Mechanistic studies support a sequential single-electron transfer (SET) and radical addition pathway. The method offers a sustainable alternative to conventional alkyne functionalization strategies.

Hierarchical Assembly of Proteinosomes and Coacervates Communities into 3D Protocellular Networks.

Drawing inspiration from the living cells, various life-inspired assemblies have been developed to mimic their remarkable properties and functionalities, and offer valuable insights into the origin of life and the understanding of life behaviors. Advancing the design and construction of multi-compartmentalized hierarchical systems with more advanced structures and functions has always increasingly attracted attention in this field. Here, a type of 3D protocellular networks are designed and constructed, which is formed by the hybrid of two types of protocells communities based on phenylboronic acid-grafted proteinosomes and polysaccharide-based coacervate microdroplets.

Hierarchical VO@Wood Aerogel Electrodes with Tunable Valence States for Enhanced Energy Storage.

Vanadium-based electrode materials are limited in practical applications, due to their low energy density, cycling instability, and poor electrochemical stability. To address these limitations, a wood-derived vanadium oxide (VO) electrode was developed through sol-gel assembly followed by thermal annealing, in which VO aerogel formed within the vertically aligned wood channels, resulting in a continuous porous network to mitigate particle aggregation and enhance ion diffusion. After thermal annealing at 800 °C, V partially converts to V, forming a mixed-valence heterostructure that significantly increases the density of redox-active sites and facilitates efficient charge transfer.

Causal association of antibody-mediated immune responses to infectious disease agents with lung cancer: a Mendelian randomization study.

Background: There is a causal relationship between many non-communicable diseases and other infectious diseases. However, the exact relationship between lung cancer and the immune response to antibodies associated with viral diseases is unclear. Compared with other traditional methods, Mendelian randomization (MR) studies reduce the influence of confounding factors, thus improving the accuracy of the results.

Water-Catalytic Deconstructive and Proton Transfer Cyclopropanation of Sulfoxonium Ylide with Olefin.

Cyclopropane rings, with their distinct structure and reactivity, have long been a focus in organic chemistry and are significant pharmacophores in medicinal chemistry. Conventional direct cyclopropanation methods for olefins do not modify the functional groups on the α- or β-carbon of olefins. Herein, a novel deconstructive cyclopropanation reaction is designed for olefins using a close-open-close ring strategy.

In-situ polymerized tourmaline/polypyrrole/lignocellulose aerogel for flame-resistant and intelligent fire alarm sensor.

Fires in buildings made of woody materials pose threats to human lives and property. Therefore, an intelligent, efficient sensors made of lignocellulosic materials for early fire warnings that can detect fires quickly and exhibit satisfactory flame retardancy is urgently needed. In this study, a flame-retardant lignocellulose aerogel (TPLA) with a thermosensitive alarm sensor response is prepared by the vacuum impregnation of tourmaline particles (TPs) and in-situ polymerization of pyrrole in lignocellulose aerogel specimens.

Z-drugs are associated with cardiovascular outcomes among patients with heart failure: a population-based cohort study in Hong Kong.

Aims: Patients with heart failure (HF) often suffered from concomitant insomnia. Non-benzodiazepine GABA receptor agonists (Z-drugs) are hypnotics commonly used for treating insomnia. The effect of Z-drugs on the outcomes of patients with HF is nonetheless sparse.

Economic burden due to hearing loss among individuals in Hebei, China.

Background: Hearing loss is a common sensory disorder that imposes a significant economic burden on both society and families. However, there is a paucity of research analyzing the economic burden of hearing loss, particularly in-depth regional analyses.

Methods: This study employed a convenience sampling method and a custom-designed questionnaire.

Synergistic Effect of Boron Doping and Porous Structures on Titanium Dioxide for Efficient Photocatalytic Nitrate Reduction to Nitrogen in Pure Water.

Photocatalytic reduction of nitrate to N holds great significance for environmental governance. However, the selectivity of nitrate reduction to N is influenced by sacrificial agents and the kinds of cocatalysts (such as Pt and Ag). The presence of unconsumed sacrificial agents can aggravate environmental pollution, while noble metal-based cocatalysts increase application costs.

Anisotropic cellulose-based phase change aerogels for acoustic-thermal energy conversion and management.

Porous materials are usually used as sound-absorbing materials to alleviate noise pollution problems. However, the heat energy conversed from the acoustic energy is wasteful. Herein, anisotropic cellulose-based phase change aerogels (MXene/CNF-C/PEG aerogels) are fabricated by facile directional freeze casting method with anisotropic porous structure, efficient sound wave absorption, acoustic-thermal conversion and thermal management capability.

Muscle-Inspired Formable Wood-Based Phase Change Materials.

Phase change materials (PCMs) are crucial for sustainable thermal management in energy-efficient construction and cold chain logistics, as they can store and release renewable thermal energy. However, traditional PCMs suffer from leakage and a loss of formability above their phase change temperatures, limiting their shape stability and versatility. Inspired by the muscle structure, formable PCMs with a hierarchical structure and solvent-responsive supramolecular networks based on polyvinyl alcohol (PVA)/wood composites are developed.

Self-Assembled MXene Supported on Carbonization-Free Wood for a Symmetrical All-Wood Eco-Supercapacitor.

As an emerging two-dimensional (2D) material, MXene has garnered significant interest in advanced energy storage systems, yet the stackable structure, poor mechanical stability, and lack of moldability limit its large-scale applications. To address this challenge, herein, the self-assembly of MXene on carbonization-free wood was obtained to serve as high-performance electrodes for symmetrical all-wood eco-supercapacitors by a steam-driven self-assembly method. This method can be implemented in a low-temperature environment, significantly simplifying traditional high-temperature annealing processes and generating minimal impact on the environment, human health, and resource consumption.

Antibacterial and Biofilm Removal Strategies Based on Micro/Nanomotors in the Biomedical Field.

Bacterial infection, which can trigger varieties of diseases and tens of thousands of deaths each year, poses serious threats to human health. Particularly, the new dilemma caused by biofilms is gradually becoming a severe and tough problem in the biomedical field. Thus, the strategies to address these problems are considered an urgent task at present.

The association between triglyceride glucose-body mass index and all-cause and cardiovascular mortality in diabetes patients: a retrospective study from NHANES database.

The triglyceride glucose body mass index (TyG-BMI) is a potential indicator for insulin resistance, but its association with mortality in diabetic patients is unclear. This study investigates the relationship between TyG-BMI and all-cause and cardiovascular mortality in diabetics. The study included 3109 diabetic patients from the National Health and Nutrition Examination Survey (2001-2018).

A colorimetric and fluorescent probe of lignocellulose nanofiber composite modified with Rhodamine 6G derivative for reversible, selective and sensitive detection of metal ions in wastewater.

Heavy metal ions have extremely high toxicity. As the top of food chain, human beings certainly will accumulate them by ingesting food and participating other activities, which eventually result in the damage to our health. Therefore, it is very meaningful and necessary to design a simple, portable, stable and efficient material for heavy metal ions detection.

Sustainable lignocellulose aerogel for air purifier with thermal insulation, flame retardancy, mechanical strength, and its life cycle assessment.

High-performance biomass materials with good thermal insulation, flame retardrancy, and mechanical properties are urgently required for thermal management. Herein, a novel lignocellulose aerogel treated using a recyclable deep eutectic solvent (DES) was physically mixed with tourmaline particles (TPs) to enhance its structural stability, flame retardancy, and mechanical properties. The optimized TPs-modified lignocellulose aerogel (TLA-4) had good comprehensive performances due to the synergistic effect of ammonium sulfate and TPs.

Intermittent Exothermic and Self-Healing Hydrated Salt Gels for Advanced Thermal Management of Underfloor Radiant Heating System.

Phase change materials (PCMs) have great prospects in thermal management applications because they can store and release latent heat. However, they are not suitable for on-demand heating as they can only release heat once. Herein, this work reports the intermittent exothermic of PCMs based on a supersaturated salt solution, exhibiting fully controlled long-term storage of energy, releasing and suspending heat on demand.

Progress in photocatalytic CO reduction based on single-atom catalysts.

Reduced CO emissions, conversion, and reuse are critical steps toward carbon peaking and carbon neutrality. Converting CO into high-value carbon-containing compounds or fuels may effectively address the energy shortage and environmental issues, which is consistent with the notion of sustainable development. Photocatalytic CO reduction processes have become one of the research focuses, where single-atom catalysts have demonstrated significant benefits owing to their excellent percentage of atom utilization.

Strain-Driven Auto-Detachable Patterning of Flexible Electrodes.

Flexible electrodes that are multilayer, multimaterial, and conformal are pivotal for multifunctional wearable electronics. Traditional electronic circuits manufacturing requires substrate-supported transfer printing, which limits their multilayer integrity and device conformability on arbitrary surfaces. Herein, a "shrinkage-assisted patterning by evaporation" (SHAPE) method is reported, by employing evaporation-induced interfacial strain mismatch, to fabricate auto-detachable, freestanding, and patternable electrodes.

Synchronous removal of emulsions and organic dye over palladium nanoparticles anchored cellulose-based membrane.

Membrane is a considerable precursor for emulsions separation and organic dyes degradation used in water purification and oil reclamation. However, the tedious preparation method, the surface smears easily, and low degradation efficiency, these characteristics usually significantly hinder its applicability toward wastewater governance. Herein, a green, facile, and efficient fabrication strategy to prepare a bi-functional palladium nanoparticles (PdNPs)-loaded bacterial cellulose membrane (BCMPd) is proposed.

Effect of proanthocyanidins on blood pressure: A systematic review and meta-analysis of randomized controlled trials.

Background: Hypertension is a common chronic disease that can lead to serious health problems. Previous studies have not drawn a consistent conclusion about the effect of proanthocyanidins (PCs) on blood pressure (BP). This systematic review and meta-analysis aims to evaluate the effect of PCs supplementation on blood pressure (BP).

Luminescent Transparent Wood Based on Lignin-Derived Carbon Dots as a Building Material for Dual-Channel, Real-Time, and Visual Detection of Formaldehyde Gas.

Formaldehyde (FA) is a widespread indoor air pollutant, and its efficient detection is a major industrial challenge. The development of a building material with real-time and visual self-detection of FA gas is highly desirable for meeting both construction and human health demands. Herein, a luminescent transparent wood (LTW) as the building material was developed for dual-channel, real-time, and visual detection of FA gas.

A Simple, Green Method to Fabricate Composite Membranes for Effective Oil-in-Water Emulsion Separation.

Most factories discharge untreated wastewater to reduce costs, causing serious environmental problems. Low-cost, biological, environmentally friendly and highly effective materials for the separation of emulsified oil/water mixtures are thus in great demand. In this study, a simple, green method was developed for separating oil-in-water emulsions.

Preparation and comparison of tacrolimus-loaded solid dispersion and self-microemulsifying drug delivery system by in vitro/in vivo evaluation.

This study aimed to compare the dissolution and the intestinal absorption of tacrolimus in self-microemulsifying drug delivery system (SMEDDS) and solid dispersion (SD). Poloxamer 188 SD was prepared by the combination of the solvent evaporation method and the freeze drying method. Hydroxypropyl methylcellulose (HPMC) SD was prepared by the solvent evaporation method combined with the vacuum drying method.

Morinda officinalis How. - A comprehensive review of traditional uses, phytochemistry and pharmacology.

Ethnopharmacological Relevance: The medicinal plant Morinda officinalisHow. (MO) and its root have long been used in traditional medicines in China and northeast Asia as tonics for nourishing the kidney, strengthening the bone and enhancing immunofunction in the treatment of impotence, osteoporosis, depression and inflammatory diseases such as rheumatoid arthritis and dermatitis.

Aim Of The Review: This review aims to sum up updated and comprehensive information about traditional usage, phytochemistry, pharmacology and toxicology of MO and provide insights into potential opportunities for future research and development of this plant.