Sleep duration and mental health in middle-aged and older adults: a study on gender differences.

Background: As the global population ages, mental health issues among middle-aged and older adults have become an important public health concern. Although the impact of sleep disorders on mental health is widely recognised, the specific mechanisms underlying the gender differences in mental health among middle-aged and older adults due to differences in sleep duration remain unclear. This study aims to explore the impact of sleep duration on mental health differences between middle-aged and older adults of different genders, providing key mechanistic evidence for understanding gender inequality in mental health among middle-aged and older adults.

Effect of short-term exposure to fine particulate matter components on respiratory mortality - evidence from a study of inland cities in China.

There is a lack of research on the association between fine particulate matter (PM) fractions and respiratory disease mortality. Therefore, this study aims to investigate how short-term exposure to fine particulate matter components affects the mortality risk of patients with respiratory diseases.We collected data on the number of respiratory deaths and fine particulate matter components, including sulfate (SO), nitrate (NO), ammonium (NH), organic matters (OM), and black carbon (BC), in Hefei, Anhui Province, between 2017 and 2020.

Epidemiological trends of laboratory-confirmed influenza cases driven by meteorological factors in Anhui Province, China: a multi-city time-series analysis.

Background: Influenza poses a significant threat to public health, potentially influenced by environmental factors. However, the role of meteorological factors (MFs) on influenza risks in China remains underexplored. This study explored the effect of MFs on laboratory-confirmed influenza (LCI) cases in Anhui, China.

The effect of mumps vaccine on the incidence of mumps in Hefei: An interrupted time-series analysis.

To quantitatively assess the incremental protective effect of two-dose mumps vaccination in Hefei. Monthly mumps incidence during 2011-2023 were collected. The Interrupted Time Series and Segmented Regression Analyses (ITSA) were employed to evaluate the variations in monthly mumps incidence following the introduction of one-dose mumps-containing vaccine (MuCV) and two-dose measles-mumps-rubella combined attenuated live vaccine (MMR) into the Expanded Program on Immunization (EPI).

Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis.

Antibiotic tolerance, by which susceptible bacteria survive at high bactericide doses, is known to cause treatment failure in clinical practice. However, the impact of antifungal tolerance on clinical outcomes remains poorly understood. Here, we observed that candidemia cases caused by echinocandin-tolerant Candida tropicalis exhibited higher mortality rates during caspofungin treatment by conducting a comprehensive seven-year retrospective analysis.

Epidemiological and etiological investigation of a rare family cluster caused by severe fever with thrombocytopenia syndrome in Anhui Province in 2023.

Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease discovered in the 21st century. Human-to-human transmission of the disease has been documented, but the mechanisms of transmission require further investigation.

Methods: Epidemiological investigations and genetic analyses of the patients were conducted, and a retrospective cohort study was performed to analyze potential risk factors for person-to-person transmission.

Heatstroke characteristics and meteorological conditions in Hefei, China: thresholds and driving factors.

Background: Due to climate change and rapid urbanization, the frequency of heatwave events in East China has increased considerably since the 21st century, which has a considerable influence on human health, such as heatstroke. However, few studies have been conducted in this region on the relationship between heatstroke and meteorological conditions. To address this point, this study aimed to analyze the characteristics of heatstroke and their relationship with meteorological conditions in Hefei, China.

Association of Di(2-ethylhexyl) Phthalate Exposure with Reproductive Hormones in the General Population and the Susceptible Population: A Systematic Review and Meta-Analysis.

Di(2-ethylhexyl) phthalate (DEHP), an environmental endocrine disruptor, has hormone-like activity and endocrine-disrupting effects. However, the types of reproductive hormones associated with DEHP vary across the studies. Thus, we conducted a systematic review and meta-analysis to pool existing epidemiological evidence.

The impact of short-term exposure to meteorological factors on the risk of death from hypertension and its major complications: a time series analysis based on Hefei, China.

Objectives: This study aimed to reveal the short-term impact of meteorological factors on the mortality risk in hypertensive patients, providing a scientific foundation for formulating pertinent prevention and control policies.

Methods: In this research, meteorological factor data and daily death data of hypertensive patients in Hefei City from 2015 to 2018 were integrated. Time series analysis was performed using distributed lag nonlinear model (DLNM) and generalized additive model (GAM).

Fine particulate matter (PM) induces the stem cell-like properties of hepatocellular carcinoma by activating ROS/Nrf2/Keap1-mediated autophagy.

Exposure to fine particulate matter (PM) has been linked to an increased incidence and mortality of hepatocellular carcinoma (HCC). However, the impact of PM exposure on HCC progression and the underlying mechanisms remain largely unknown. This study aimed to investigate the effects of PM exposure on the stem cell-like properties of HCC cells.

Bone metastasis is a late-onset and unfavorable event in survivors of gastric cancer after radical gastrectomy: Results from a clinical observational cohort.

Background: The timing and incidence of recurrent bone metastasis (BM) after radical gastrectomy in patients with gastric cancer (GC) as well as the survival of these patients were not fully understood. The aim of this study was to analyze the data of an observational GC cohort and identify patients who underwent curative gastrectomy and had recurrent BM to describe and clarify the pattern and profile of BM evolution after surgery.

Methods: Data were retrieved from a hospital-based GC cohort, and patients who underwent upfront radical gastrectomy were selected.

Tea consumption and risk of bone health: an updated systematic review and meta-analysis.

Introduction: Current research evaluating the association between tea consumption and bone health still has inconsistent findings.

Materials And Methods: The electronic databases of Embase, PubMed, Scopus, and Web of Science were systematically searched from inception until December 2022 to identify eligible studies. The calculation of summary relative risks (RRs) and 95% confidence intervals (CIs) was carried out using random-effects models.

Analysis of spatial-temporal distribution characteristics and natural infection status of SFTS cases in Hefei from 2015 to 2021.

Background: To analyze the prevalence and spatial-temporal characteristics of severe fever with thrombocytopenia syndrome (SFTS), clustering mode of transmission, and the serological dynamic detection results in multiple areas in Hefei from 2015 to 2021, and to provide the basis for SFTS prevention and control.

Method: Case data were obtained from the Chinese Disease Control and Prevention Information System. Information on the clustering outbreak was obtained from the outbreak investigation and disposal report.

Association between ambient air pollution and thyroid hormones levels: A systematic review and meta-analysis.

Background: Growing studies have focused on the effects of ambient air pollution on thyroid hormones (THs), but the results were controversial. Therefore, a systematic review and meta-analysis was conducted by pooling current evidence on this association.

Methods: Four databases were searched for studies examining the associations of particulate matter [diameter ≤10 μm (PM) or ≤2.

Role of ROS-mediated PERK/ATF4 signaling activation in extracorporeal tube formation injury of human umbilical vein endothelial cells induced by cooking oil fume PM exposure.

Cooking oil fume-derived PM (COF-PM) is a major source of indoor air contamination in China, which has been demonstrated to be a hazard factor of cardiovascular and cerebrovascular diseases. This study aimed to investigate the role of ROS-mediated PERK/ATF4 signaling activation in COF-PM-inhibited extracorporeal tube formation in human umbilical vein endothelial cells (HUVECs). HUVECs were treated with 100 μg/mL COF-PM at different times, with or without 100 nM PERK activity inhibitor GSK2606414 (GSK) or 200 μM antioxidant N-acetylcysteine (NAC) pretreatment.

An Autoregressive Integrated Moving Average Model for Predicting Varicella Outbreaks - China, 2019.

Introduction: Varicella, a prevalent respiratory infection among children, has become an escalating public health issue in China. The potential to considerably mitigate and control these outbreaks lies in surveillance-based early warning systems. This research employed an autoregressive integrated moving average (ARIMA) model with the objective of predicting future varicella outbreaks in the country.

Highly Prevalent SARS-CoV-2 Antigenemia in COVID-19 Patients.

Background: Many issues, such as severity assessment and antibody responses, remain to be answered eagerly for evaluation and understanding of COVID-19. Immune lesion is one of key pathogenesis of the disease. It would be helpful to understand the disease if an investigation on antigenemia and association was conducted in the patients with SARS-CoV-2 infection.

Epidemiological characteristics and transmissibility of HPV infection: A long-term retrospective study in Hokkien Golden Triangle, China, 2013-2021.

Objective: Multiple human papillomavirus (HPV)-associated diseases have put a significant disease burden on the world. Therefore, we conducted a study to explore the epidemiological characteristics of HPV and the transmissibility of its genotypes.

Methods: HPV testing data was collected from Hospital.

Characteristics, sources and health risk assessment of trace metals and polycyclic aromatic hydrocarbons in PM from Hefei, China.

Trace metals (TRs) and polycyclic aromatic hydrocarbons (PAHs) are major toxic components of fine particulate matter (PM) and related to various health adverse outcomes. The study aims to get a better understanding of the contents, sources and risks of PM-bounded TRs and PAHs in Hefei, China, during the period of 2019-2021. We collected 504 samples and measured twelve TRs and sixteen priority PAHs by inductively coupled plasma mass spectrometry and high-performance liquid chromatography.

Trends and seasonal variation of antibiotic consumption by community residents in Hefei, China, 2012-2016.

Objectives: The aim of this study was to evaluate the trends and seasonal variations of antibiotic consumption by community residents in Hefei, China, over a 5-year period.

Study Design: This was an ecological study.

Methods: Data on antibiotic consumption by community residents in Hefei between 2012 and 2016 were collected from the Hefei Center for Disease Control and Prevention.

Coffee, Green Tea Intake, and the Risk of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis of Observational Studies.

Several studies suggest an inverse relationship between coffee intake and risk of hepatocellular carcinoma (HCC), but the association between green tea intake and the risk of HCC is still inconclusive. We performed a meta-analysis of observational studies to clarify the association. We identified eligible studies published from January 1, 1992, to February 28, 2022, by searching PubMed, Web of Science, and EMBASE.