Kinetic and Mechanistic Discrepancies of Single/Dual-Atom Nanozymes Drive a Triple-Channel Sensing Array for Machine Learning-Assisted Antioxidant Discrimination.

Current colorimetric sensing arrays for antioxidant detection often struggle with discrimination due to cross-reactive signals from individual nanozymes. These signals are typically modulated by external factors such as pH or chromogenic substrates, offering limited kinetic and mechanistic diversity. To overcome this, we present a novel triple-channel colorimetric sensing array utilizing two distinct single-atom nanozymes (Cu SA and Fe SA) and one dual-atom nanozyme (CuFe DA).

Heart disease risk prediction based on deep learning multi-scale convolutional enhanced Swin Transformer model.

Heart disease is a leading global cause of death, making early prediction critical. This study proposes a multi-scale convolution-enhanced Swin Transformer (MSCST) model for heart disease risk assessment. The model employs a multi-branch convolutional network with channel attention to extract and optimize multi-scale features.

Heterointerface-Enhanced Active Hydrogen Generation in Ru/RuOx/CNTs for Nitrate Reduction to Ammonia at Low Overpotentials.

Ru/RuOx/CNTs heterostructured materials are synthesized using an in situ method. The Ru─RuOx heterostructure facilitates active hydrogen dissociation, leading to excellent catalytic performance in nitrate reduction, with ammonia as the primary product at low overpotentials. The process achieves Faradaic efficiencies of ammonia exceeding 90% and a production rate of 1.

Unusual Nonlinearity and Nonexponentiality in Glass-Forming Polymers Governed by Ionic Interactions.

The glass transition is dynamically heterogeneous with non-Arrhenius, nonexponential, and nonlinear features, and those parameters are mutually correlated in most cases. This study systematically investigates these interrelated features through thermodynamic analysis of polyvinylpyrrolidone (PVP)/salt complexes, employing enthalpy relaxation parameters, specifically the heat capacity jump (Δ) at and enthalpy hysteresis (Δ). Notably, the introduction of ionic interactions induces simultaneous reductions in dynamic fragility (), nonexponential parameter (β), and nonlinear parameter (), thereby disrupting their previously established empirical correlations.

Host-Guest Metal Interaction in Cu-In Single Atom Alloy Switching Electrocatalytic CO Reduction Pathway.

The catalytic behavior of alloy electrocatalyst is strongly influenced by host-guest metal interaction, which governs adsorption energy and product selectivity. However, in conventional bimetallic alloy systems, the catalyst composition and the geometric configuration often obscure the identification of critical active sites. Here, we investigate the host-guest metal interaction in Cu-In single atom alloy (SAA) catalysts, demonstrating a remarkable switching of electrochemical CO reduction reaction (CORR) pathway.

A survey of Simon, 1882 (Araneae, Oonopidae) from Xishuangbanna, China, with descriptions of eight new species.

Eight new species and one known species of the oonopid spider genus Simon, 1882 are described or recorded based on material collected from forest canopy of Xishuangbanna, Yunnan Province, southwestern China: (♂♀), Tong & Li, 2011 (♂♀), Tong & Li, (♂♀), Tong & Li, (♂♀), Tong & Li, (♂♀), Tong & Li, (♂♀), Tong & Li, (♂♀), Tong & Li, (♂♀) and Tong & Li, (♂♀). An identification key to these nine species is provided.

Controlled chain-walking ethylene oligomerization in the gas-phase for hyperbranched ethylene oligomers.

Gas-phase polymerization is typically employed for the synthesis of high-molecular-weight crystalline polyolefin materials, yet the production of low-molecular-weight hyperbranched ethylene oligomers this method is seldom reported. In this study, we utilized flexible bulky iminopyridyl Pd(II) catalysts to catalyze the gas-phase oligomerization of ethylene, resulting in the preparation of hyperbranched ethylene oligomers. These catalysts demonstrated higher activity and stability comparable to those observed in solution polymerization, yielding hyperbranched ethylene oligomers with lower branching density and higher molecular weights.

Chloroplast genome comparison and taxonomic reassessment of Polygonatum sensu Lato (Asparagaceae): implications for molecular marker development in traditional medicinal plants.

The Polygonati Rhizoma have generated significant market attention for their medicinal and culinary applications. However, morphological similarities and ambiguous species boundaries complicate the identification of genera and species, thereby impeding product development and utilization within Polygonatum sensu lato. Despite the widespread application of the chloroplast genome for taxonomic boundary revisions for Polygonatum s.

Trans-scale hierarchical metasurfaces for multispectral compatible regulation of lasers, infrared light, and microwaves.

Electromagnetic scattering control of optical windows has significant challenges in improving optical transmission and compatibility, especially for multispectral and large-angle incidences, due to material and structure mismatches. This paper presents trans-scale hierarchical metasurfaces (THM) to achieve wide-angle optical transmission enhancement and electromagnetic scattering-compatible regulation in dual-band lasers, and infrared and microwave ranges. THM comprises an ultrafine hollow metal array (UHMA) and a transmission-enhanced micro-nanocone array (TMCA).

Two New Species of Sect. From Sichuan, China.

In groups undergoing rapid radiations, species delimitation among phylogenetically close sister lineages has long been a challenge. During plant surveys in northwestern Sichuan, we unexpectedly discovered two putative new species of that are morphologically similar yet distinct from each other. These species resemble , which has been assigned to sect.

Genome-based phylogenetics and species delimitation for the narrowly distributed Pachyhynobius salamander (Caudata: Hynobiidae) reveal cryptic biodiversity.

Species delimitation is a challenging issue in taxonomy, especially in the absence of clear diagnostic morphological characters, a particular problem for cryptic species. In recent years, the rapid development of high-throughput sequencing technologies, when combined with genomic species delimitation methods such as the multispecies coalescent, has significantly improved the ability to resolve cryptic species. However, traditional methods like Bayesian phylogenetics and phylogeography often result in over-splitting due to their failure to fully consider factors such as gene flow.

A Highly Expressed and Conserved Odorant Receptor for Identifying the Alarm Pheromone ()-2-Decenal in .

()-2-decenal is the alarm pheromone of and other Pentatomidae bugs as well. This chemical can trigger avoidance behavior from dangerous sources or defensive behavior against predators, thereby playing a crucial role in the survival and flourishing of the population. Revealing the molecular mechanism underlying this stink bugs's perception of alarm pheromone will facilitate the development of environmentally friendly biological control agents.

The effects of an integrated sports and arts intervention on response joint attention (RJA) eye-movement characteristics in children with mild autism.

This study examines whether integrating sports and arts interventions enhances response joint attention (RJA) in children with mild autism and provides insights for diversifying intervention strategies for autism. 2024.6-2024.

Ligand-Engineered All-In-One Cu(I) Iodide Complex Enables Near-Unity Photoluminescence and Advanced 3D X-ray Image Reconstruction.

High-performance X-ray detectors are essential for 3D X-ray imaging in computed tomography (CT), but conventional systems require high radiation doses to achieve fine resolution. All-In-One (AIO) Cu(I) halide complexes, capable of forming both ionic and coordinate bonds within a single structure, offer efficient scintillation at lower doses, yet their performance remains limited by nonradiative energy losses during indirect X-ray-to-light conversion. Here, we develop rigid-cation-assisted AIO Cu(I) halide complexes by introducing π-π interactions to suppress the nonradiative pathways, achieving near-unity photoluminescence quantum yield (PLQY).

Biochar-Immobilized Enhances Copper Remediation and Growth of Chinese Milk Vetch ().

Heavy metal-contaminated soil poses a severe threat to environmental quality and human health, calling for eco-friendly and efficient remediation strategies. This study explored the use of biochar-immobilized copper-resistant to remediate copper-contaminated soil and promote growth of Chinese milk vetch ( L.).

Genome-Wide Identification and Expression Analysis of the Gene Families in .

The gene family is a widely distributed and highly conserved transcription factor (TF) family in plants, with its members playing key roles in plant growth and development, stress response, and metabolism. Although TFs have been extensively studied in many plant species, research on the gene family in Thunb. remains limited.

Identification of Two Critical Contact Residues in a Pathogenic Epitope from Tetranectin for Monoclonal Antibody Binding and Preparation of Single-Chain Variable Fragments.

Sepsis is a fetal disease that requires a clear diagnostic biomarker for timely antibiotic treatment. Recent research has identified a pyroptosis-inducing epitope known as P5-5 in tetranectin (TN), a plasma protein produced by monocytes. Previously, we produced a 12F1 monoclonal antibody against the P5-5 and discovered that it could not only diagnose the presence but also monitor the progress of sepsis in the clinic.

NIR-activatable aza-BODIPY nanoparticles for photoacoustic imaging and synergistic NO-photothermal cancer therapy.

Near-infrared (NIR) photothermal therapy (PTT) has emerged as a promising modality for cancer treatment due to its minimal invasiveness, precise spatiotemporal control, and potent therapeutic outcomes. However, the clinical application of photothermal agents (PTAs) remains limited by issues such as poor biodegradability, long-term toxicity, and insufficient photothermal conversion efficiency. Herein, we report the development of a novel amphiphilic aza-boron-dipyrromethene (aza-BODIPY)-based photothermal agent, C-NBDP-OEG, which self-assembles into monodisperse nanoparticles in aqueous solution.

Facet-Engineered Highly Active and Stable Ag/TiO Photocatalysts for Selective Oxidative Coupling of Methane.

The oxidation of methane into valuable chemicals, like C molecules, has long been pursued, yet the trade-off between a high yield and high selectivity remains unresolved. Here, we demonstrate efficient methane upgrading via photocatalytic oxidative coupling of methane (POCM) using Ag-decorated facet-engineered TiO. {001}-dominated TiO exhibits exceptional performance, delivering a C production rate of 2.

Chiral polymer dots for ratiometric enantioselective monitoring of D-cysteine in the brains of Alzheimer's disease mice.

It is imperative to develop reliable chiral discrimination methods to detect enantiomer D-cysteine (D-Cys) involved in brain chemistry to further understand its functions in pathological and physiological events in brains. We herein fabricated an integrated polymer dot (Pdot)-based nanoprobe, BFD@Ch-pdots, derived from a newly designed chiral polymer and Cys-responsive dye for ratiometric imaging of D-Cys in cells and brains. The Pdots exhibited high enantioselectivity, good biocompatibility, and efficient blood-brain barrier (BBB) penetration.

Construction of dibenzo[1,4]oxazocines palladium-catalysed arylalkylation of allenamides.

Efficient access to eight-membered N-heterocycles through a palladium-catalysed dicarbofunctionalization of allenamides has been developed. The allyl-palladium intermediate, which was generated an intramolecular allene insertion reaction, underwent allylic substitution with carbon-anion nucleophiles to form dibenzo[1,4]oxazocine derivatives with broad functional group tolerance under mild reaction conditions.

Effects of landscape fragmentation on floodplain fishes as revealed by species-habitat networks.

How species interact with habitat patches is influenced primarily by habitat configuration (e.g., connectivity) and species' functional traits.

Chiral Phosphoric Acid-Catalyzed Asymmetric Doyle Indolization: Enantiodivergent Access to Indolizinylindoles.

We present here a chiral phosphoric acid-catalyzed asymmetric Doyle indolization enabling efficient construction of axially chiral indolizinylindoles with stable C-N stereogenic axes. Importantly, this intriguing cascade cyclization realized the highly enantioselective synthesis of axially chiral quarteraryl skeletons containing two contiguous stereogenic axes in good to high yields and excellent stereoselectivities. Furthermore, an atropo-divergent synthesis was achieved via switching the 3,3'-substituents of the CPA catalyst.

Legal barriers and reflections on the use of assisted reproductive technology by single women in China.

This study analyzed the legal obstacles on the access to assisted reproductive technology (ART) by single women in mainland China, focusing on the period from 2001 to 2024, and reassessed the Chinese regulatory framework. The study employed legal text data sourced from the PKU Law database, and the case data from the China Judgments Online. Results revealed that the Chinese prevailing legislative framework prohibits single women to use ART and the courts oppose egg freezing for this group too, which creating regulatory obstacles to their reproductive rights.

-Loaded Bioglue with Antibacterial, Antioxidant, and Immunomodulatory Properties for Accelerated Wound Healing.

Biological glue (bioglue) can noninvasively seal and reattach wound tissue outside the hospital, which has been extensively studied recently. Nevertheless, the commercial bioglue lacks constant oxygen supply, antioxidation, and anti-inflammation, three other key factors for bacteria-infected wound healing in plateau areas. Herein, a multifunctional bioglue (LA-DESP/ε-PLL@) is simply fabricated by encapsulating into a matrix composed of α-lipoic acid (LA), α-lipoic acid sodium (LANa), and ε-polylysine (ε-PLL).