Facet-Engineered Highly Active and Stable Ag/TiO Photocatalysts for Selective Oxidative Coupling of Methane.

The oxidation of methane into valuable chemicals, like C molecules, has long been pursued, yet the trade-off between a high yield and high selectivity remains unresolved. Here, we demonstrate efficient methane upgrading via photocatalytic oxidative coupling of methane (POCM) using Ag-decorated facet-engineered TiO. {001}-dominated TiO exhibits exceptional performance, delivering a C production rate of 2.

Iron-anthraquinone cooperative catalysis enables mild C-C bond cleavage of cyclohexanones oxygen-centered radicals.

This study introduces an Fe/anthraquinone dual catalytic system for oxidative cleavage of non-strained cyclohexanones to mono-carboxylic acids under mild visible-light conditions (0 °C). Efficient activation of inert C-C bonds oxygen-centered radical-mediated cleavage is achieved, providing a sustainable approach to valorize bulk chemicals and synthesize pharmaceutical intermediates.

Palladium-catalyzed tandem cyclization reaction: access to isoxazoline-benzofuran bis-heterocycles.

A novel palladium-catalyzed carboetherification reaction of β,γ-unsaturated ketoxime with -dihaloolefin has been developed. This process offers an efficient route for the assembly of isoxazoline-linked benzofuran/indole bis-heterocycles in moderate to good yields. The scalability of the reaction and subsequent transformations of the products highlight the synthetic potential of this developed method.

Clinical effects of modified Halo-pelvic traction in patients with severe spinal deformities and respiratory disorders.

Objective: Effects of first-stage Halo-pelvic traction (HPT) combined with second-stage surgery in patients with severe scoliosis and pulmonary insufficiency.

Methods: A retrospective analysis was conducted on the clinical data of 100 patients with scoliosis and pulmonary insufficiency admitted to the Beijing Da Wang Road Emergency Rescue Hospital from January 2021 to October 2024. All patients underwent primary HPT traction treatment and secondary scoliosis correction surgery.

The safety and efficacy of transarterial embolization with detachable coils for complex visceral artery aneurysm.

Detachable coils grant controlled deployment, retrieval, and repositioning until desired placement is achieved for complex visceral artery aneurysms (VAAs), but a detailed investigation is needed for its clinical application. Between June 2018 and September 2020, 28 patients with 31 complex VAAs successfully treated with detachable coils in two hospitals were retrospectively analyzed. The technical success rate reached 100%.

Generated Ti over Ag/TiO Enables Highly Efficient Photocatalytic Oxidative Coupling of Methane in Flow Reactors.

Photocatalytic oxidative coupling of methane (OCM) is a promising sustainable technology for chemical and fuel synthesis, but current photocatalysts suffer from limited activity and selectivity. Here, we report a highly active Ag/TiO catalyst for OCM in a flow reactor, achieving a C hydrocarbon production rate of 1.9 mmol g h and selectivity of up to 92% with enhanced stability exceeding 150 h.

Photocatalytic direct dehydrogenative coupling of alcohols using α-cyclodextrin decorated sulfur quantum dots.

Sulfur quantum dots, a new type of non-metallic quantum dots, have gained widespread attention as a promising alternative material. In this work, we synthesized aqueous sulfur quantum dots modified with α-cyclodextrin (CD-S dots) by hydrothermal method. Under visible light irradiation, CD-S dots could promote the dehydrogenative cross-coupling reaction of alcohols and amines to produce imine products.

Spectroscopic Kinetic Insights into the Critical Role of Metal-Oxide Interfaces in Enhancing the Concentration of Surface-Reaching Photoexcited Charges.

Surface modification of semiconductors with noble metals has been shown to effectively tune their photocatalytic activity. However, the photoinduced charge transfer processes at the metal/semiconductor interface and their impact on the concentration of surface-reaching photoexcited charges remain subjects of ongoing debate. In this study, we used time-resolved spectroscopy and kinetic analysis to investigate the behavior of surface-reaching photoholes in metal-loaded TiO nanoparticles.

The PSO-IFAH optimization algorithm for transient electromagnetic inversion.

As a non-contact method, the transient electromagnetic (TEM) method has the characteristics of high efficiency, small impact of device, no limitation of site range, and high resolution, and is a hot topic in current research. However, the research on the refined data processing method of TEM is lag, which seriously restricts the application in superficial engineering investigation and is a key problem that needs to be solved urgently. The particle swarm optimization (PSO) algorithm and firefly algorithm (FA) were successful swarm intelligence algorithms inspired by nature.

Accelerated interfacial hole transfer over Au/TiO photocatalysts for highly efficient oxidative coupling of methane.

Accelerated interfacial hole transfer over Au/TiO photocatalysts facilitates a highly efficient oxidative coupling of methane, achieving a C hydrocarbon production rate of 3.3 mmol g h and selectivity of up to 97%.

Visible-Light-Induced Divergent Oxygenation of Methylbenzene Utilizing Aryl Halides.

The selective oxidation of methylbenzene to value-added products is of indisputable importance in organic synthesis. Although photocatalytic oxidation reactions of toluene have achieved great success for the preparation of its oxidative products, such as carboxylic acids, benzaldehyde, and benzoate, there remains a lack of a unified photocatalytic system for the selective preparation of these oxidation products. Herein, we report a metal- and additive-free photocatalytic protocol enabled by aryl halides using O as a green oxidant for the selective synthesis of the above-mentioned three oxidation products by adjusting the reaction solvent.

Atomic-Level Asymmetric Tuning of the Co-NP Catalyst for Highly Efficient -Alkylation of Amines with Alcohols.

Despite the extensive development of non-noble metals for the -alkylation of amines with alcohols, the exploitation of catalysts with high selectivity, activity, and stability still faces challenges. The controllable modification of single-atom sites through asymmetric coordination with a second heteroatom offers new opportunities for enhancing the intrinsic activity of transition metal single-atom catalysts. Here, we prepared the asymmetric N/P hybrid coordination of single-atom Co-NP by absorbing the Co-P complex on ZIF-8 using a concise impregnation-pyrolysis process.

Linking the Doping-Induced Trap States to the Concentration of Surface-Reaching Photoexcited Holes in Transition-Metal-Doped TiO Nanoparticles.

Transition-metal doping has been demonstrated to be effective for tuning the photocatalytic activity of semiconductors. Nonetheless, the impact of doping-induced trap states on the concentration of surface-reaching photoexcited charges remains a topic of debate. In this study, through time-resolved spectroscopies and kinetic analysis, we found that the concentration of surface-reaching photoholes () in doped TiO nanoparticles sensitively relies on the type of dopants and their associated trap states.

Gene Amplification of Mediator Subunit 30 Redirects the MYC Transcriptional Program and Oncogenesis.

Understanding the molecular mechanisms underlying tumorigenesis is crucial for developing effective cancer therapies. Here, we investigate the co-amplification of MED30 and MYC across diverse cancer types and its impact on oncogenic transcriptional programs. Transcriptional profiling of MYC and MED30 single or both overexpression/amplification revealed the over amount of MED30 lead MYC to a new transcriptional program that associate with poor prognosis.

Synergistic effect between InO and ZrO in the reverse water gas shift reaction.

Efficient activation of CO at low temperature was achieved through the interface effect between InO and ZrO by their geometric and electronic effects. The results show that 75InO-25ZrO (InO : ZrO molar ratio of 3 : 1), as a catalyst for the reverse water gas shift reaction, can achieve 28% CO conversion with 96% CO selectivity at 400 °C, 0.1 MPa, a H : CO molar ratio of 3 : 1 and a gas hourly space velocity of 10 000 mL g h.

Recent Advances in Palladium-Catalyzed Asymmetric Heck/Tsuji-Trost Reactions of 1,n-Dienes.

Transition-metal catalyzed tandem asymmetric reactions were powerful tools to access various chiral compounds. Many strategies have been developed for the coupling of 1,n-dienes with aryl halides via a tandem Heck/Tsuji-Trost process. However, the control of regio- and stereo-chemistry remains a challenging task.

Low-Temperature Synthesis of Cyano-Rich Modified Surface-Alkalinized Heterojunctions with Directional Charge Transfer for Photocatalytic In Situ Generation and Consumption of Peroxides.

The synthesis of low-temperature poly(heptazine imide) (PHI) presents a significant challenge. In this context, we have developed a novel low-temperature synthesis strategy for PHI in this work. This strategy involves the introduction of Na ions, which etch and disrupt the conjugated structure of carbon nitride (CN) during assisted thermal condensation.

Recyclable -Heterocyclic Carbene Porous Coordination Polymers with Two Distinct Metal Sites for Transformation of CO to Cyclic Carbonates.

Single-component catalysts with integrated multiple reactive centers could work in concert to achieve enhanced activity tailored for specific catalytic reactions, but they remain underdeveloped. Herein, we report the construction of heterogeneous bimetallic porous coordination polymers (PCPs) containing both porphyrin and -heterocyclic carbene (NHC) metal sites via the coordinative assembly of the NHC functionalities. Three heterobimetallic PCPs (, and ) have been prepared to verify this facile synthetic strategy for the first time.

Endovascular Denervation for the Improvement of Limb Ischemia in Patients with Peripheral Artery Disease: A Randomized Clinical Trial.

Background: To evaluate the safety and efficacy of endovascular denervation (EDN) as an adjunct to percutaneous vascular intervention (PVI) for peripheral artery disease (PAD).

Methods: From August 2019 to April 2021, 38 eligible patients with PAD enrolled in this study were randomly and equally assigned into 2 groups: the PVI group and the PVI + EDN group treated with EDN at the iliac and femoral arteries before PVI. The primary endpoint was the improvement in the ankle brachial index at 6 months after the procedure.

EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma.

Growth factor receptors rank among the most important oncogenic pathways, but pharmacologic inhibitors often demonstrate limited benefit as monotherapy. Here, we show that epidermal growth factor receptor (EGFR) signaling repressed N-methyladenosine (mA) levels in glioblastoma stem cells (GSCs), whereas genetic or pharmacologic EGFR targeting elevated mA levels. Activated EGFR induced non-receptor tyrosine kinase SRC to phosphorylate the mA demethylase, AlkB homolog 5 (ALKBH5), thereby inhibiting chromosomal maintenance 1 (CRM1)-mediated nuclear export of ALKBH5 to permit sustained mRNA mA demethylation in the nucleus.

Influence of kyphosis in ankylosing spondylitis on cardiopulmonary functions.

This paper aims at analyzing the characteristics of cardiopulmonary functions in the patients with ankylosing spondylitis (AS), and exploring the influence of global kyphosis (GK) on cardiopulmonary functions. Clinical data of 46 patients with AS and kyphosis, who had been admitted in our hospital from October 2021 to October 2022, were analyzed retrospectively. According to the to global kyphosis (GK) angle, 23 subjects were divided into Severe Group (GK > 95°), and 23 subjects were divided into in the Moderate Group (80° ≤ GK ≤ 95°).

Disconnection of Network Hubs Underlying the Executive Function Deficit in Patients with Ischemic Leukoaraiosis.

Background: Cognitive impairment is the most common clinical manifestation of ischemic leukoaraiosis (ILA), but the underlying neurobiological pathways have not been well elucidated. Recently, it was thought that ILA is a "disconnection syndrome". Disorganized brain connectome were considered the key neuropathology underlying cognitive deficits in ILA patients.

Placement of Bare Self-Expanding Metal Stent for Isolated Superior Mesenteric Artery Dissection.

Background: To evaluate the safety and efficacy of placing bare self-expanding metal stent (SEMS) for treating isolated superior mesenteric artery dissection (ISMAD).

Method: Patients with ISMAD who received bare SEMS from January 2014 to December 2021 at the authors' center were included. Baseline characteristics, clinical manifestation, radiological findings, and treatment outcomes, including symptom relief and SMA remodeling, were analyzed.