Identification and characterization of the first G8P[1] sheep rotavirus strain in China: Genetic similarity to human rotavirus and zoonotic potential.

Rotavirus (RV) is a major cause of gastroenteritis in both humans and many mammals, including livestock. However, information regarding RV in sheep remains limited, particularly in China. This study reports the first isolation and characterization of the G8-P[1]-I2-R2-C2-M2-A11-N2-T6-E2-H3 type sheep RV strain (GS13) in China.

Memory-induced long-range order in dynamical systems.

Time nonlocality, or memory, is a nonequilibrium property shared by all physical systems. Here, we show that memory is sufficient to induce a phase of spatial long-range order (LRO) even if the system's primary dynamical variables are coupled locally. This occurs when the memory degrees of freedom have slower dynamics than the primary degrees of freedom.

Pharmaceuticals in drinking water in suburban communities in Chengdu, China: potential risks on the human health.

Water supplies have come under serious environmental stress in suburban communities in China due to developmental activities. A comprehensive study was carried out to investigate the occurrence of pharmaceutical compounds in county-level drinking water sources within Chengdu City. The solid-phase extraction combined with ultra-high performance liquid chromatography/tandem mass spectrometry was employed to analyze the residues of pharmaceuticals in the water sources for water supply in Chengdu.

Pyroptosis, a double-edged sword during pathogen infection: a review.

Pyroptosis, a distinctive form of programmed cell death (PCD) characterized by its inflammatory nature, is triggered by the activation of pore-forming proteins known as gasdermins (GSDMs). This process is marked by progressive expansion of a pore within the cell, ultimately leading to cellular membrane disruption and the substantial release of intracellular contents. Pyroptosis plays a pivotal role in the eradication of intracellular pathogen replication niches and in the modulation of the immune system through the release of danger signals.

Emission Characteristics of Evaporative Intermediate-Volatility Organic Compounds from In-Use Gasoline Vehicles.

The evaporation of intermediate-volatility organic compounds (IVOCs) from vehicle emissions substantially contributes to secondary organic aerosol (SOA) and ozone (O) formation. However, the limited characterization of evaporative IVOCs from in-use vehicles leads to uncertainties in assessing their atmospheric impact. Herein, aided by two-dimensional gas chromatography-mass spectrometry and flame ionization detectors (2D-GC-MS/FID), the highly resolved composition of IVOCs from in-use light-duty gasoline vehicles (LDGVs) are comprehensively characterized, revealing that the proportion of unresolved complex mixtures (UCMs) significantly decreased to 2.

Reproducing Strong Urban Oxidation Capacity in Beijing Using an Empirical Parametrization.

Atmospheric oxidation processes drive the conversion of primarily emitted compounds to secondary pollutants, with the hydroxyl radical (OH) as the predominant oxidant. In urban areas, the OH concentration is extremely useful to determine the formation rate of secondary pollutants (i.e.

An Efficient Algorithmic Way to Construct Boltzmann Machine Representations for Arbitrary Stabilizer Code.

Restricted Boltzmann machines (RBMs) have demonstrated considerable success as variational quantum states; however, their representational power remains incompletely understood. In this work, we present an analytical proof that RBMs can exactly and efficiently represent stabilizer code states-a class of highly entangled quantum states that are central to quantum error correction. Given a set of stabilizer generators, we develop an efficient algorithm to determine both the RBM architecture and the exact values of its parameters.

Increased Urban Ozone in Heat Waves due to Temperature-Induced Emissions of Anthropogenic Volatile Organic Compounds.

Urban ozone (O) pollution correlates with temperature, and higher O often occurs during heat waves, threatening public health. However, limited data on how anthropogenic volatile organic compound (AVOC) precursor emissions vary with temperature hinders understanding their impact on O. Here, we show that the increase in non-combustion AVOC emissions (e.

Effects of Water Content on the Combustion Characteristics of Hydrous Ethanol/RP-3 Mixed Fuel.

Constant volume chamber (CVC) was adopted to measure the laminar burning velocity (LBV) and Markstein length of hydrous ethanol/RP-3 mixed fuel at initial temperature = 450 K, initial pressure = 0.1 MPa, and equivalence ratio ϕ = 0.8-1.

Targeted discovery of diterpene compounds ostamycins with anti-influenza a viral activity from a deepsea-derived Streptomyces strain.

Heterologous expression of a nonconventional terpene biosynthetic gene cluster from the deepsea-derived Streptomyces amphotericinicus DS22-01 led to the production of a novel cyclic diterpene, ostamycin A (1). Anti-influenza A virus activity evaluation revealed that compound 1 showed significant activity with an IC value of 4.72 μM, which was much stronger than that of the positive control ribavirin (IC = 20.

BVOCs' role in dynamic shifts of summer ozone formation regimes across China and policy implications.

Biogenic volatile organic compounds (BVOCs) are crucial players in atmospheric chemistry, significantly impacting the formation of tropospheric ozone (O₃). While China has made substantial strides in reducing anthropogenic VOC (AVOCs) emissions, O₃ levels persist, highlighting the complex interplay between biogenic and anthropogenic sources. A critical knowledge gap exists in understanding how BVOC emissions influence ozone formation regimes (OFRs) and how this knowledge can inform effective air quality policies.

High-Performing Nanofiber Memristor via Field-Induced Ion Migration Concentration at Highly-Curved Interwoven Interface.

Memristors with high computing capabilities hold significant potential as processing devices in the era of information explosion, but their applications are largely hindered by the trade-off between memristive performance and operation uniformity. Extensive efforts are devoted to designing or regulating memristive layers of memristors to improve device performance, while few studies focused on the interface structure at cross points of memristors. Herein, inspired by the tip effect, a nanofiber memristor with highly-curved interwoven interface is designed by assembling nanofiber electrodes using dielectrophoretic method.

Genomic Differences and Mutations in Epidemic Orf Virus and Vaccine Strains: Implications for Improving Orf Virus Vaccines.

Orf (ORF) is an acute disease caused by the Orf virus (ORFV), and poses a certain threat to animal and human health. Live attenuated vaccines play an important role in the prevention and control of ORF. The effectiveness of the live attenuated Orf virus vaccine is influenced by several factors, including the genomic match between the vaccine strain and circulating epidemic strains.

Deciphering decadal urban ozone trends from historical records since 1980.

Ozone pollution is a major environmental threat to human health. Timely assessment of ozone trends is crucial for informing environmental policy. Here we show that for the most recent decade (2013-2022) in the northern hemisphere, warm-season (April-September) mean daily 8-h average maximum ozone increases much faster in urban regions with top ozone levels (mainly in the North China Plain, 1.

Investigation of the Cyclohexene Oxidation Mechanism Through the Direct Measurement of Organic Peroxy Radicals.

Monoterpenes, the second most abundant biogenic volatile organic compounds globally, are crucial in forming secondary organic aerosols, making their oxidation mechanisms vital for addressing climate change and air pollution. This study utilized cyclohexene as a surrogate to explore first-generation products from its ozonolysis through laboratory experiments and mechanistic modeling. We employed proton transfer reaction mass spectrometry with NH ion sources (NH-CIMS) and a custom-built OH calibration source to quantify organic peroxy radicals (RO) and closed-shell species.

The Mediating Role of School Adaptation in the Impact of Adolescent Victimization from Bullying on Mental Health: A Gender Differences Perspective.

Purpose: The primary aim of this study is to investigate the mediating role of school adaptation in the impact of adolescent bullying victimization on mental health, as well as the gender differences therein. These findings offer a novel perspective for parents and educators, aiding bullied adolescents in managing and addressing mental health concerns.

Methods: The primary data source for this study was the 2020/2021 Adolescent Health Theme Database from the China Population Health Data Center (PHDA).

Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD.

Lung parenchyma destruction represents a severe condition commonly found in chronic obstructive pulmonary disease (COPD), a leading cause of morbidity and mortality worldwide. Promoting lung regeneration is crucial for achieving clinical improvement. However, no therapeutic drugs are approved to improve the regeneration capacity due to incomplete understanding of the underlying pathogenic mechanisms.

An improved identity-based public audit protocol for cloud storage.

With the rapid development of informatization, a vast amount of data is continuously generated and accumulated, leading to the emergence of cloud storage services. However, data stored in the cloud is beyond the control of users, posing various security risks. Cloud data auditing technology enables the inspection of data integrity in the cloud without the necessity of data downloading.

Severe community‑acquired pneumonia caused by in combination with influenza A subtype (H1N1) virus in an immunocompetent patient detected by metagenomic next‑generation sequencing: A case report.

Legionella pneumonia is an atypical form of pneumonia caused by that can also lead to multiple organ diseases, including acute respiratory distress syndrome and multiple organ dysfunction syndrome. requires a long incubation period for culture in clinical practice using BCYE medium. The specificity of serum for serological detection is low, resulting in a relatively high rate of missed diagnoses.

Two novel compounds inhibit Flavivirus infection and by targeting lipid metabolism.

Unlabelled: Flavivirus infection capitalizes on cellular lipid metabolism to remodel the cellular intima, creating a specialized lipid environment conducive to viral replication, assembly, and release. The Japanese encephalitis virus (JEV), a member of the genus, is responsible for significant morbidity and mortality in both humans and animals. Currently, there are no effective antiviral drugs available to combat JEV infection.

Collective dynamics and long-range order in thermal neuristor networks.

In the pursuit of scalable and energy-efficient neuromorphic devices, recent research has unveiled a novel category of spiking oscillators, termed "thermal neuristors." These devices function via thermal interactions among neighboring vanadium dioxide resistive memories, emulating biological neuronal behavior. Here, we show that the collective dynamical behavior of networks of these neurons showcases a rich phase structure, tunable by adjusting the thermal coupling and input voltage.