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http://dx.doi.org/10.1073/pnas.2423915122 | DOI Listing |
Chem Sci
August 2025
Department of Chemistry, Dartmouth College Hanover New Hampshire 03755 USA
Azo-BF complexes are visible and near-infrared (NIR) light-activated photoswitches showcasing versatility in applications ranging from energy storage to three-dimensional displays. While highly appealing as molecular switches, factors that affect their photophysical properties and solution-state reactivity still need to be teased out. In this paper, we present the synthesis and characterization of two azo-BF analogues (1 and 2), each modified with structurally distinct dimethylamine-substituted naphthalene moieties.
View Article and Find Full Text PDFJ Am Chem Soc
August 2025
Vagelos Laboratory for Energy Science and Technology, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Facilitating different chemistries between the rare earth (RE = La-Lu, Sc, Y) ions is of significant interest for their separations. While the bulk of attention has been on maximizing the small differences in their ground state chemistry, interest is beginning to shift toward the differences in their electronic excited states. In this work, we demonstrate modulation of the photostationary state of an azobenzene derivative, Na, via chelation to a series of REDO3A (DO3A = 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid) complexes.
View Article and Find Full Text PDFJ Am Chem Soc
July 2025
Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 3, Groningen 9747 AG, The Netherlands.
Powering light-driven molecular motors with visible or near-infrared (NIR) light is essential in the design of molecular machines, bringing dynamic functions to the next generation of responsive materials particularly for biological applications. However, current strategies suffer from heavy molecular substitution and low photoefficiency of excitation, limiting their practical use in bulk materials and biomolecular systems. Here, we report a general and highly efficient strategy to power NIR light-driven molecular motors via a radiative energy transfer mechanism.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Chemistry Department, Marburg University, Hans-Meerwein-Straße 4, 35043, Marburg, Germany.
Oxygen levels and its distribution are tightly regulated due to their critical impact on health. Hypoxia-inducible factors (HIFs) are traditionally recognized as key regulators of the transcriptional response to low oxygen (hypoxia). Recent research expanded their functions, highlighting their potential as therapeutic targets.
View Article and Find Full Text PDFChem Commun (Camb)
July 2025
Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, USA.
We explored alkyne-functionalized hydrazone photoswitches and enhanced their performance, achieving improved UV resolution, higher photostationary states, and tunable alkyne shifts (up to 34 cm), establishing hydrazones as promising high-resolution Raman spectroscopy imaging probes.
View Article and Find Full Text PDF