Protective Effects of Pectin From Honey-Processed Hawthorn on Acute Myocardial Ischemia.

Previous studies have shown that both hawthorn and honey-processed hawthorn (HH) can prevent heart injury in acute myocardial ischemia (AMI). Hawthorn pectin (HP) and stir-fried hawthorn pectin (FHP) have been identified as protective agents against AMI, with the effects closely related to their structural characteristics. This study aims to investigate the effects of pectin of HH (HHP) in preventing AMI.

Absolute Quantitative Detection of Hypervirulent Using a Novel Silicon-Doped Carbon Quantum Dot-Probe-Graphene Oxide.

() is a common opportunistic pathogen, with hypervirulent strains (hv) posing significant risks even to healthy individuals. Traditional clinical diagnostics often use real-time quantitative polymerase chain reaction (PCR) with TaqMan probes, which are costly and unstable due to their reliance on fluorophore and quencher molecules. This study introduces a novel probe using silicon-doped carbon quantum dots (Si-QDs) and single-layer graphene oxides (GOs), forming the Si-QD-probe-GO.

Spin-Polarization-Activated - Orbital Coupling Enables Optimal Oxygen Reduction Reaction of Cobalt.

The spin configuration of electrons is inherently linked to catalytic activity, particularly in the oxygen reduction reaction (ORR). Since the regulation of electron distribution in the orbital of a metal center affects the spin state greatly, the adsorption behavior of active sites is influenced by intermediates. Herein, a straightforward adsorption-pyrolysis strategy was employed to co-anchor Co and S atoms onto amorphous carbon (CoNS, = 1, 2, 3).

Elucidation of the potential mechanism of Euphorbiae Pekinensis Radix and Glycyrrhizae Radix for the remission of ascites in hepatocellular carcinoma using a comprehensive strategy based on chinmedomics, pharmacology, and biopharmaceutics.

As recorded in Traditional Chinese medicine (TCM) theory, Euphorbiae Pekinensis Radix (EPR) and Glycyrrhizae Radix (GR) compose one herbal pair of the so-called "Eighteen Incompatible Medicaments". The EPR-GR combination has displayed potential in the treatment of malignant ascites. However, the validity of this theory has been challenged due to insufficient evidence.

L. f.: a review on the botany, phytochemistry, ethnopharmacology, pharmacology, toxicology and comprehensive utilization.

L.f. (), a perennial herb of the genus Aster in the Asteraceae (Compositae) family.

Fabrication of whey protein isolate fibrils-gallic acid complex high internal-phase Pickering emulsions: Dual functionality as a fat substitute and antioxidant.

This study develops high internal-phase Pickering emulsions using whey protein isolate fibrils complexed with gallic acid to replace fat and enhance antioxidant properties in food. Hydrophobic interactions and hydrogen bonding stabilized complexes, with zeta potential increasing from 26.56 ± 0.

Hydrogen Sulfide Alleviates Schizophrenia-Like Behavior Through Regulating Apoptosis by S-Sulfhydrylation Modification.

Background: We initiated an exploration of the relationship between hydrogen sulfide (HS) and Schizophrenia (SZ) as well as its mechanism at the three levels of population study, cellular investigation, and animal model.

Materials And Methods: Clinical data and peripheral blood samples from 78 patients with SZ and 83 healthy controls (HC) were collected for the detection of HS levels (ChiCTR (Chinese Clinical Trial Registry) 900026776). MK801 (Dizocilpine) was used to establish SZ models in cells and rats, with sodium hydrosulfide (NaHS) serving as an exogenous HS donor.

Reinventing the High-rate Energy Storage of Hard Carbon: the Order-degree Governs the Trade-off of Desolvation-Solid Electrolyte Interphase at Interfaces.

In alkali metal-ion battery systems, the electrolyte enables being decomposed on the electrode surface to form a solid electrolyte interphase (SEI) film. In principle, a thin, uniform SEI film facilitates the enhancement of the performance of the cell. Herein, we successfully distinguish the effects of desolvation behavior and SEI process on the kinetic behavior of hard carbon (HC) electrodes by adopting the strategy of switching the electrolyte interface model to modulate the properties of SEI film.

Discovery of natural few-layer graphene on the Moon.

Natural few-layer graphene is unambiguously identified from the Chang'e-5 lunar soil samples, which serves as a new platform for investigating extraterrestrial bodies.

The neurodevelopmental regulatory role and clinical value of hsa-circ-CORO1C-hsa-miR-708-3p-JARID2 + LNPEP axis in early-onset schizophrenia.

Genes discovered by previous epigenetic studies of schizophrenia have focused solely on diagnostics or pathology, potentially leading to a disconnection between them. Using these molecules to identify the disease is considered insufficient. MicroRNAs (miRNAs) binding to messenger RNAs (mRNAs) can lead to mRNA degradation, while circular RNAs (circRNAs), by binding to miRNAs as sponge, can reduce the inhibitory effect of miRNAs on mRNAs.

Dynamic changes in chemical components, volatile profile and antioxidant properties of Xanthoceras sorbifolium leaf tea during manufacturing process.

In order to elucidate the dynamic changes of quality characteristics in Xanthoceras sorbifolium leaf tea (XLT), this work investigated the chemical components, volatile profile, and antioxidant properties at key stages of fixation, shaping, and drying. The process of fixation and drying emerged as critical stages that affected the chemical components and taste of XLT. Total polyphenols, reducing sugars and chlorophyll were the differential compounds, which decreased by 29.

A real-time feeding behavior monitoring system for individual yak based on facial recognition model.

Feeding behavior is known to affect the welfare and fattening efficiency of yaks in feedlots. With the advancement of machine vision and sensor technologies, the monitoring of animal behavior is progressively shifting from manual observation towards automated and stress-free methodologies. In this study, a real-time detection model for individual yak feeding and picking behavior was developed using YOLO series model and StrongSORT tracking model.

Experimental study on the piezoresistive effect of Mn-Cu alloy under high temperature and pressure and its application.

Large volume presses are used to simulate extreme environments within the Earth, enabling the investigation of the physical properties of subsurface materials. However, existing pressure calibration methods do not facilitate in situ observation of continuously varying chamber pressures. The Mn-Cu alloy, known for its piezoresistive properties, has not been extensively studied under ultra-high temperatures.

In Situ Surface Exsolution of Chang'e-5 Lunar Soil Architected by the Trinity Effect of Electron Beam.

It is known that the interaction between electron beam and material surface enables a variety of physical phenomena, which hold significant inspiration for functional application. Herein, the process of in situ surface exsolution was observed and documented for the basalt phase in the Chang'e-5 lunar samples via scanning electron microscopy. Energy dispersive x-ray spectroscopy analysis confirmed the main existence of metal oxides such as plagioclase and pyroxene.

Hawthorn pectin plays a protective role in myocardial ischaemia by regulating intestinal flora and short chain fatty acids.

Studies have shown that there is a close relationship between acute myocardial ischaemia (AMI) and intestinal flora imbalance. And pectin has a protective effect on AMI and regulates intestinal flora. Raw hawthorn pectin from hawthorn (RHP) is high methoxyl pectin, which is able to protect injury induced by AMI.

Comprehensive Investigation of Homology and Heterogeneity Between Aurantii Fructus and Aurantii Fructus Immaturus Using Chemometrics Combined with Network Pharmacology.

Aurantii Fructus (AF) and Aurantii Fructus Immaturus (AFI) are distinct herbs outlined by the Chinese Pharmacopoeia. They are sourced from the same plant but harvested at different times, resulting in differences in efficacy. It is important to avoid mixing them clinically and to distinguish between the two.

Botany, Traditional Use, Phytochemistry, Pharmacology and Quality Control of : Comprehensive Review.

, as a traditional Chinese medicine, is the name of the genus in the family. Documented in the Tang Herbal Medicine (Tang Dynasty, AD 657-659), its medicinal properties cover a wide range of applications such as acute mastitis, lung abscess, conjunctival congestion, sore throat, damp-heat jaundice, and vision improvement. In the Chinese Pharmacopoeia (Edition 2020), more than 40 kinds of China-patented drugs containing were recorded.

A key regulator of tumor-associated neutrophils: the CXCR2 chemokine receptor.

In recent years, with the advance of research, the role of tumor-associated neutrophils (TANs) in tumors has become a research hotspot. As important effector cells in the innate immune system, neutrophils play a key role in the immune and inflammatory responses of the body. As the first line of defense against bacterial and fungal infections, neutrophils have the ability to kill invading pathogens.

Development of a proton CT imaging system using scintillator-based range detection.

Background: The accuracy of proton therapy and preclinical proton irradiation experiments is susceptible to proton range uncertainties, which partly stem from the inaccurate conversion between CT numbers and relative stopping power (RSP). Proton computed tomography (PCT) can reduce these uncertainties by directly acquiring RSP maps.

Purpose: This study aims to develop a novel PCT imaging system based on scintillator-based proton range detection for accurate RSP reconstruction.

Cobalt substitution-induced π-donation in NiMoO for enhanced electrochemical charge storage.

NiMoO (NM) has garnered significant attention due to its rich d-orbital electronic structure and multivalent electroactive cations. However, the inherently low electrical conductivity of NM limits its reaction kinetics. Herein, cobalt-substituted NM (Co-NM) nanorods were prepared via a hydrothermal reaction followed by subsequent thermal treatment.

A review of the botany, phytochemistry, pharmacology, synthetic biology and comprehensive utilization of .

(L.) Gaertn, a herbaceous plant with a long history in traditional medicine for the treatment of hepatobiliary diseases, particularly in Europe, which has attracted attention for its remarkable therapeutic effect. This review systematically summarizes the research progress in the botany, phytochemistry, pharmacology, comprehensive utilization and synthetic biology of .

A multidimensional strategy for uncovering comprehensive quality markers of based on UPLC-Q-TOF-MS analysis, artificial neural network, network pharmacology analysis, and molecular simulation.

Introduction: (SR), derived from the root of Georgi, is a traditional Chinese medicine (TCM) for clearing heat and cooling blood. It has been used as a traditional herbal medicine and is popular as a functional food in Asian countries today.

Methods: In this study, UPLC-Q-TOF-MS was first employed to identify the chemical components in the ethanol extract of SR.

The Rhododendron Chrysanthum Pall.s' Acetylation Modification of Rubisco Enzymes Controls Carbon Cycling to Withstand UV-B Stress.

Lysine acetylation of proteins plays a critical regulatory function in plants. A few advances have been made in the study of plant acetylproteome. However, until now, there have been few data on Pall.