Development and validation of the time perspective scale of perceived benefits and harms of internet gaming among adolescents in China.

Background And Aims: Gaming-specific maladaptive cognitions were critical determinants of internet gaming disorder (IGD). This study was novel to develop and validate the Time Perspective Scale of Perceived Benefits and Harms of Internet Gaming (TPS-PBHIG) by integrating the concepts of present- and future-oriented time perspectives, perceived benefits, and perceived harms of internet gaming.

Methods: Item generation was conducted by using both inductive (focus group interviews among adolescents) and deductive (comprehensive literature review) approaches.

Effects of steaming practices on the cadmium distribution in edible tissues of the swimming crabs () and its health risk assessment.

This study investigated the redistribution of cadmium (Cd) in edible tissues of swimming crabs () during steaming and evaluated associated human health risks. Experimental results demonstrated that Cd was significantly transferred from brown meat to leg muscles, resulting in a nearly tenfold increase in Cd concentration in steamed leg muscles compared to raw tissues. Human health risk assessment results indicate that the target cancer risk (TCR) values for brown meat and cooking liquor range from 1.

Protective effect of scutellarin on myocardial cells treated with high glucose.

Diabetic cardiomyopathy (DCM) is an important cause of death in patients with diabetes. DCM can be simulated by cardiomyocyte injury induced by high glucose (HG) . Scutellarin (Scu) is a flavonoid extracted from .

Corydalis yanhusuo Polysaccharides regulates HPA-axis mediated microglia activation and inhibits astrocyte A1 transformation to improve depression-like behavior.

Depression is a common emotional disorder characterized by persistent low mood and decreased interest. Corydalis yanhusuo polysaccharides (CYP) are extracts from Corydalis yanhusuo, which have the effects of promoting blood circulation, relieving pain, anti-inflammation, and neuroprotection. This study investigates the effects and its underlying mechanisms of CYP in a chronic unpredictable mild stress (CUMS)-induced depression model using C57BL/6J mice.

Wenqing Yin Attenuates the Allergic Contact Dermatitis Response by Inhibiting the JAK2/STAT1 and MAPK Signaling Pathways.

Objective: Allergic contact dermatitis (ACD) is a delayed-type inflammatory skin illness, and its incidence rate is 10-20%. Wenqing Yin (WQY) is a classic prescription commonly used to treat ACD in China and Japan, and this study aims to explore the pharmacological effect and therapeutic mechanism of WQY to treat ACD.

Methods: The pharmacological effect of WQY were investigated using a mouse model caused by 2,4-dinitrofluorobenzene, and the Th1 and Th2 cells numbers in spleen were measured.

Proteomic analysis of egg white proteins under different crude protein levels in laying hens' diets.

Background: Dietary crude protein levels (DCPLs) have been shown to influence the quality of egg albumen, but the molecular implications of different DCPLs on the protein profile of albumen remain unclear. This study aimed to investigate the proteomic changes in the albumen of eggs from laying hens fed a corn-soybean meal-based diet with two different DCPLs (14.5% or 17.

The association between a stress-is-enhancing mindset and internet gaming disorder was mediated by behavioral disengagement among medical undergraduate students: a multi-center survey in China.

Background: The stress-is-enhancing mindset has beneficial effects on physical, psychological, and emotional well-being. However, its association with internet gaming disorder (IGD) had not been investigated. By integrating stress mindset into the cognitive evaluation process of commonly used stress coping theories, this study examined the association between stress mindset and IGD and explored relevant mediation mechanisms via behavioral disengagement.

Optimizing low crude protein diet: Evaluating Glycine as a conditionally essential Amino Acid.

Global interest has emerged in implementing low crude protein (LCP) diets for poultry. The necessity of their development stems from low-cost formulation, maintaining egg quality, and environmental impacts, including health and welfare concerns for current egg production in the world. Researchers have conducted several studies to provide biochemical insights into the effect of LCP on laying hen diets, but practical limitations of LCP diets still exist.

Comprehensive Insights of Biochemical and Sensory Characterization in by Environmental Modulation.

This study systematically deciphers a comprehensive analysis of biochemical and sensory variations in , evaluating the seasonal dynamics, salinity gradients (0 and 3‱), and nutritional regimes on quality determinants in aquaculture. To the best of our knowledge, the mechanistic links between cultivation factors and organoleptic quality were first established through integrative biochemical profiling, including proximate composition, free amino acids, taste-active nucleotides, and mineral ions, coupled with quantitative sensory evaluation. The results revealed that spring samples exhibit 44.

Exploration of Traditional Chinese Medicine Comprehensive Treatment of Triple Negative Breast Cancer Based on Molecular Pathological Mechanism.

Triple-negative breast cancer (TNBC) is recognized as the most aggressive subtype of breast cancer and is associated with poor prognosis. Clinically, TNBC is associated with significant invasiveness, high propensity for metastasis, frequent recurrence, and unfavorable outcomes. The absence of estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 (HER2) in TNBC renders it unresponsive to endocrine therapies and treatments that target HER2.

A Randomized, Double-Blind, Placebo-Controlled Trial Protocol Using the Fuzhengxiaoliu Patch for the Management of Primary Liver Cancer Pain.

Objective: Chronic pain strongly affects the quality of life of patients with liver cancer pain. Safe and effective management of cancer-related pain is a worldwide challenge. Traditional Chinese medicine (TCM) has rich clinical experience in the treatment of cancer pain.

Ontogeny and function of the intestinal epithelial and innate immune cells during early development of chicks: to explore in ovo immunomodulatory nutrition.

Intestinal epithelial cells (IECs) and innate immune cells in the gastrointestinal tract (GIT) of chickens play crucial roles in pathogens defense and maintaining gut health. However, their effectiveness influenced with their developmental and functional stages during pre and post hatch periods of chick. During embryonic development, differentiation and migration of these innate immune systems are tightly regulated by diverse cellular and molecular factors.

Development and validation of rapid screening of 192 veterinary drug residues in aquatic products using HPLC-HRMS coupled with QuEChERS.

The presence of veterinary drug residues in aquatic products represents a significant challenge to food safety. The current detection methods, limited in both scope and sensitivity, underscore the urgent need for more advanced techniques. This research introduces a swift and potent screening technique using high-performance liquid chromatography-high-resolution mass spectrometry (HPLC-HRMS) and a refined QuEChERS protocol, allowing simultaneous qualitative and semi-quantitative analysis of 192 residues.

Research status and challenges of Mycoplasma pneumoniae pneumonia in children: A bibliometric and visualization analysis from 2011 to 2023.

Background: Mycoplasma pneumoniae (MP) infections occur in regional outbreaks every 3 to 7 years, lasting up to 2 years. Since this fall, there has been a significant rise in MP infections among children in China, indicating a regional epidemiological trend that imposes an increased national public health burden. To date, bibliometric methods have not been applied to studies on MP infection in children.

School climate and school identification as determinants of smoking conventional cigarettes or vaping among adolescents in China: Stress-coping mediation mechanisms.

Introduction: Smoking conventional cigarettes or vaping (SV) poses significant health threats to adolescents. School climate and school identification are key elements of the school environment and potential factors of SV. Based on the Stress Coping Theory, the mediations between school climate/school identification and SV, via perceived stress/active coping, were examined.

Copper-containing POM-based hybrid P2Mo22V4Cu4 nanocluster as heterogeneous catalyst for the light-driven hydroxylation of benzene to phenol.

The current traditional phenol production process has many shortcomings, and the efficient and clean photocatalytic one-step oxidation to phenol is gradually attracting attention. Heteropolyacids (PMoV) with high-density Lewis acid active sites and excellent photoelectron transfer ability are ideal choices for catalytic reactions. In this study, a copper-modified isolated dimeric hybrid nanocluster, [Cu(pyim)][Cu(pyim)(PMoVI20MoV2VIV4O)]·(HO) (pyim = [2-(pyridin-2-yl)imidazole]), was synthesized by a convenient hydrothermal method.

An iron-containing POM-based hybrid compound as a heterogeneous catalyst for one-step hydroxylation of benzene to phenol.

It is a major challenge to perform one-pot hydroxylation of benzene to phenol under mild conditions, which replaces the environmentally harmful cumene method. Thus, finding highly efficient heterogeneous catalysts that can be recycled is extremely significant. Herein, a (POM)-based hybrid compound {[Fe(pyim)(CHO)][Fe(pyim)(HO)][PMoV2MoVI9VIV3O]}·HO (pyim = 2-(2-pyridyl)benzimidazole) (Fe2-PMo11V3) was successfully prepared by hydrothermal synthesis using typical Keggin POMs, iron ions and pyim ligands.

Characteristics of arsenic speciation in mainly cultured shellfish from Sanmen Bay, Zhejiang Province, China.

Sanmen Bay plays a crucial role in economic shellfish aquaculture in China, yet few studies exist on the arsenic speciation of shellfish from this area. In this study, arsenic speciation of 11 cultured shellfish species from Sanmen Bay were analyzed by HPLC/ICP-MS. The results showed that organic arsenic particularly AsB, was the dominant arsenic species, constituting 21 %-71 % of the total arsenic.

Development, validation, and implementation of an ultratrace analysis method for the determination of moenomycin A, in aquatic animal products.

Moenomycin A, an antimicrobial growth promoter widely used as an additive in aquaculture feedstuffs, has been restricted for use in the European Union and China due to its potential risk of promoting resistant strains of pathogenic bacteria and causing residues in aquatic animal products. Although methods for analyzing moenomycin A in feedstuffs have been developed, no established method exists for aquatic matrices. In this study, we present, for the first time, a sensitive and validated high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method for the determination of moenomycin A in aquatic animal products.

MoO-templated LnNi heterometallic clusters with large low-field magnetic entropy.

The anionic template method is an effective strategy for synthesizing high-nuclearity transition-lanthanide (3d-4f) heterometallic clusters. Herein, two lanthanide clusters with formulas [GdNi(μ-OH)(CO)(IDA)(CHNO)(CO)(MoO)(μ-OH)(HO)]Cl·79HO (1) and [TbNi(μ-OH)(CO)(IDA)(CHNO)(CO)(MoO)(μ-OH)(HO)]Cl·32HO (2) were synthesized by introducing MoO anions as templates. Structural analysis indicates that compounds 1 and 2 are isomorphic, featuring a fascinating triangular-shaped metal framework.

Two bimetal-doped (Fe/Co, Mn) polyoxometalate-based hybrid compounds for visible-light-driven CO reduction.

Two polyoxometalate (POM)-based hybrid compounds have been successfully designed and constructed by the hydrothermal method with molecular formulas [K(HO)FeII0.33Co(HO)(DAPSC)]{[FeII0.33Co(HO)(DAPSC)][FeII0.

Research advances in endometriosis-related signaling pathways: A review.

Endometriosis (EM) is characterized by the existence of endometrial mucosa outside the uterine cavity, which causesinfertility, persistent aches, and a decline in women's quality of life. Both hormone therapies and nonhormone therapies, such as NSAIDs, are ineffective, generic categories of EM drugs. Endometriosis is a benign gynecological condition, yet it shares a number of features with cancer cells, including immune evasion, survival, adhesion, invasion, and angiogenesis.

Highly Sensitive Determination of Antibiotic Residues in Aquatic Products by High-Performance Liquid Chromatography-Tandem Mass Spectrometry.

Antibiotic drug residues are crucial to ensure food safety and minimize risk to human health. Herein, a sensitive high-performance liquid chromatography−tandem mass spectrometry (HPLC−MS/MS) method was developed and validated for the determination of antibiotic residues (mainly amphenicols) consisting of chloramphenicol (CAP), thiamphenicol (TAP), florfenicol (FF), and florfenicol amine (FFA) in aquatic products. Amphenicols were well separated on a Kinetex F5 (100 mm × 3.

Scutellarin Improves Type 2 Diabetic Cardiomyopathy by Regulating Cardiomyocyte Autophagy and Apoptosis.

Diabetes cardiomyopathy has metabolic disorder and abnormality of cardiomyocytes, which is closely related to autophagy or apoptosis of cardiomyocytes. Scutellarin (SCU) is an important monomer extracted from (vant.) Hand.