Developing a predictive nomogram model for incidence of adverse outcomes in oral and maxillofacial tumor patients undergoing free flap reconstruction.

Background: Surgical treatment of oral and maxillofacial tumors is complex, and the factors contributing to adverse outcomes remain incompletely understood. This study aimed to identify independent risk factors and develop an efficient nomogram for predicting such outcomes.

Methods: Potential risk factors were identified using univariate logistic regression, followed by multivariate logistic regression to determine independent predictors.

T2T Genomes Unveil Centromere Architecture and Adaptive Divergence in Large Yellow Croaker (Larimichthys crocea).

The large yellow croaker (Larimichthys crocea) is a key aquaculture species, yet gaps in high-quality genomes hinder studies of centromeric and adaptive evolution. This study presents two telomere-to-telomere (T2T), gapless genomes from the Min-Yuedong (MYD) and Daiqu (DQ) populations, which diverged 4.18 million years ago.

The effects of landscape on visual preference and fatigue recovery among university students: Differences in gender, grade level and major.

Exposure to natural landscapes has been shown to affect both physiological and psychological well-being, with the extent of these effects varying across different landscape types. However, the underlying mechanisms remain poorly understood. The association among stress reduction, environments characteristics and individual differences requires further investigation, particularly considering the complexity of landscape attributes and the variability of personal responses.

Three-Dimensional Ordered Porous SnO Nanostructures Derived from Polystyrene Sphere Templates for Ethyl Methyl Carbonate Detection in Battery Safety Applications.

As lithium-ion batteries (LIBs) gain widespread use, detecting electrolyte-vapor emissions during early thermal runaway (TR) remains critical to ensuring battery safety; yet, it remains understudied. Gas sensors integrating oxide nanostructures offer a promising solution as they possess high sensitivity and fast response, enabling rapid detection of various gas-phase indicators of battery failure. Utilizing this approach, 3D ordered tin oxide (SnO) nanostructures were synthesized using polystyrene sphere (PS) templates of varied diameters (200-1500 nm) and precursor concentrations (0.

Fast simulation method of lithography latent image on non-planar wafer for large area mask.

The wafer topography can cause undesirable light scattering during lithographic imaging, affecting the quality of the photoresist profile. Lithography rigorous simulation can predict latent images on non-planar wafers for large area masks, but it is time-consuming. This paper presents a one-to-many deep learning network designed to learn the 3D distribution of latent images distribution from masks and topography patterns.

Securing and optimizing optical transmission in quantum wells using OAM and advanced modulation techniques.

Orbital Angular Momentum (OAM) has gained significant attention in wireless communication, particularly for high-speed, large-capacity optical wireless communication (OWC) systems. However, current optical transmission methods encounter challenges in efficiently transmitting data due to limited OAM mode generation, reduced transmission privacy, and high atmospheric turbulence. The paper proposes an optimized and secure optical transmission in quantum wells to overcome these limitations using OAM and advanced modulation approaches.

Silk fibroin coating on biometals: processing, anti-corrosion and biofunctionality.

As a natural protein, silk fibroin (SF) has been widely used in the biomedical field due to its excellent biocompatibility. Recent research has explored its potential as a multifunctional coating for biometals. This paper comprehensively reviews the processing approaches, anti-corrosion capability, and biofunctionalization of SF coatings.

Expert consensus on digital restoration of complete dentures.

Digital technologies have become an integral part of complete denture restoration. With advancement in computer-aided design and computer-aided manufacturing (CAD/CAM), tools such as intraoral scanning, facial scanning, 3D printing, and numerical control machining are reshaping the workflow of complete denture restoration. Unlike conventional methods that rely heavily on clinical experience and manual techniques, digital technologies offer greater precision, predictability, and efficacy.

A foodborne outbreak of Paratyphi C in a Chinese middle school: Genomic tracing and epidemiological characterization.

Background: Paratyphi C is an infrequent etiological agent of enteric fever, with sporadic cases primarily reported in Asia and Africa. Documented outbreaks remain exceedingly rare, and epidemiological data on such events are notably scarce.

Methods: This study investigated a paratyphoid fever outbreak caused by Paratyphi C at a secondary school in China in 2023.

An Integrated Microfluidic Platform for Label-Free Sorting and Functional Assessment of Neutrophils in Sepsis.

Neutrophil motility dysfunction, including impaired deformation and chemotaxis, contributes to reduced bacterial clearance and uncontrolled infections in sepsis. Dynamic, quantitative assessment of these parameters holds promise for early diagnosis and prognosis, yet no integrated, label-free platform currently enables neutrophil sorting and functional analysis. We developed a microfluidic cell sorting chip (CS chip) capable of isolating white blood cells (WBCs) from ≤50 μL of whole blood with >80% purity and >90% viability.

[Effect of moxibustion on small intestinal mucosal immune barrier in rats with diarrhea-predominant irritable bowel syndrome].

Objective: To observe the effect of moxibustion on small intestinal mucosal immune barrier in rats with diarrhea-predominant irritable bowel syndrome (IBS-D) and explore its underlying mechanisms.

Methods: Of 38 newborn rats from 4 healthy SPF pregnant rats, 12 neonatal rats were randomly selected in a normal group. IBS-D model was prepared by the combined measures for the rest rats, including neonatal maternal separation, acetic acid enema and chronic restraint stress.

FGA, a new target of histone acetylation, inhibits apoptosis of granulosa cells in follicles.

Granulosa cells (GCs) are the main supporting cells for follicles, and histone acetylation has been reported to regulate follicular development. However, the mechanism of histone acetylation regulating follicular development is still unclear in GCs. In this study, we found that FGA, fibrinogen alpha chain, mediated the survival and fate of GCs.

Effects of Acute Abdomen III on Sepsis-Induced Intestinal Damage in a Rat Model.

The disruptions to intestinal integrity contribute to sepsis-related complications. Acute abdomen III is a traditional Chinese medicine formula. The objective of this research is to investigate the impact of acute abdomen III upon sepsis-induced intestinal damage.

Amplified emission and lasing enabled by high-Q quasi-bound states in asymmetric dielectric metasurfaces via eigenfield perturbation.

Symmetry-protected bound states in the continuum represent a distinct class of nonradiative modes in continuous media. By introducing asymmetric parameters into a symmetric metasurface, the inherent symmetry can be broken, transforming BICs-originally decoupled from external radiation channels-into high-Q quasi-BICs with controlled radiation capabilities. However, manufacturing constraints pose a significant challenge in fabricating nanostructures with ultra-small asymmetric parameters, thereby limiting the achievable Q-factor.

Management of Meloidogyne incognita with the endophytic fungus Beauveria bassiana.

Background: Meloidogyne incognita root-knot nematodes (RKNs) pose a significant threat to crops, ranking among the most dangerous plant pathogens globally. Entomopathogenic fungi (EPF) have been reported to reduce populations of plant-pathogenic nematodes, including M. incognita.

Short-term efficacy of ultrasound-guided capsule-preserving hydrodilatation for primary frozen shoulder using 5% dextrose water vs. corticosteroid: a randomized controlled trial.

Background: To compare the short-term efficacy of capsule-preserving hydrodilatation with 5% dextrose water (D5W) vs. glucocorticoids (GCs) for the treatment of primary frozen shoulder (PFS).

Methods: A prospective randomized, controlled, noninferiority trial.

Nonlinear Metasurfaces for Completed Control of Amplitude, Phase, and Polarization in Broadband Terahertz Generation.

Terahertz (THz) generation is a crucial initial step in THz applications. However, the current THz sources face challenges in fully controlling the propagation properties of generated THz waves without the use of external devices. This limitation leads to bulky systems with unavoidable insertion losses and bandwidth constraints.

METTL3 Inhibition Restores PD-L1 Expression and CD8+ T-cell Cytotoxic Function in Immunotherapy-Treated Gastric Cancer.

The efficacy of immunotherapy targeting PD-1/PD-L1 in gastric cancer depends on PD-L1 expression levels and the infiltration of immune cells within the tumor microenvironment (TME). Although methyltransferase-like 3 (METTL3) plays a role in the development and progression of gastric cancer, its mechanism of regulating the TME in gastric cancer remains unclear. In this study, we demonstrated that the expression of PD-L1 is regulated by METTL3.

Opioid-Free versus Opioid-Sparing Anesthesia for Postoperative Pain and Early Recovery After Laparoscopic Cholecystectomy: A Randomized Controlled Trial.

Purpose: Enhanced recovery after surgery emphasizes effective analgesia while minimal opioid use. Opioid-free anesthesia (OFA) and opioid-sparing anesthesia (OSA) have been shown to enhance recovery by reducing opioid-induced side effects. This study compared the efficacy of OFA and OSA in managing postoperative pain and recovery after laparoscopic cholecystectomy (LC).

Comparative study of wear properties of CAD/CAM PEEK materials, resin ceramics and dental enamel under simulated chewing conditions.

Objectives: To compare the impact-sliding wear properties of CAD/CAM polyetheretherketone (PEEK) materials and resin ceramics with dental enamel, and to investigate the corresponding wear mechanisms.

Methods: Six CAD/CAM polymer materials were assessed in comparison with human tooth enamel. Hardness, modulus and roughness values of each group were measured, prior to wear testing in a chewing simulator (ball-on-disc design, 49 N).

DNA Methylation Mediates the Transcription of to Regulate During Follicular Development.

Maturation of follicles is the primary condition for the initiation of puberty, and excessive apoptosis of granulosa cells (GCs) will hinder the normal development of follicles in pigs. Signal Transducer and Activator of Transcription 4 () plays an important role in cell proliferation and apoptosis. However, the mechanism of DNA methylation regulating transcription and affecting follicle development in pigs remains unclear.

METTL1 aggravates sepsis-acute kidney injury by promoting m7G methylation of NLRP3-mediated pyroptosis.

Sepsis is a major cause of acute kidney injury (AKI). Dysregulation of N7-methyladenosine (m7G) methylation is a pathogenic mechanism of sepsis. However, the role of m7G methylation in renal damage remains poorly understood.

Physics-based forward model for near-real-time quantitative imaging of spent nuclear fuel assemblies.

The Passive Gamma Emission Tomography (PGET) instrument, authorized by the International Atomic Energy Agency (IAEA) for verification of spent nuclear fuel, aims to reconstruct 2D cross-sectional images of spent fuel assemblies (SFAs), identify missing or present fuel pins, and quantify fuel pin activities. Although the first two objectives are reliably achieved, accurate determination of fuel pin activities remains a challenge due to intense self-shielding and scattering effects. We have developed a linear inverse approach that addresses these effects and demonstrated superior image quality and identification accuracy in simulation studies.

The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project.

Genetic mutation and drift, coupled with natural and human-mediated selection and migration, have produced a wide variety of genotypes and phenotypes in farmed animals. We here introduce the Farm Animal Genotype-Tissue Expression (FarmGTEx) Project, which aims to elucidate the genetic determinants of gene expression across 16 terrestrial and aquatic domestic species under diverse biological and environmental contexts. For each species, we aim to collect multiomics data, particularly genomics and transcriptomics, from 50 tissues of 1,000 healthy adults and 200 additional animals representing a specific context.

Carbon price prediction research based on CEEMDAN-VMD secondary decomposition and BiLSTM.

The carbon market is an institutional innovation that utilizes market mechanisms to address climate change. In recent years, carbon markets have been established worldwide to achieve lower cost carbon reduction through market mechanisms. Accurate carbon price prediction is of great significance for the construction, development, and improvement of emerging carbon markets, as well as guiding carbon investment behavior.