The large yellow croaker (Larimichthys crocea) is a key aquaculture species, yet gaps in high-quality genomes hinder studies of centromeric and adaptive evolution. This study presents two telomere-to-telomere (T2T), gapless genomes from the Min-Yuedong (MYD) and Daiqu (DQ) populations, which diverged 4.18 million years ago.
View Article and Find Full Text PDFUnderstanding how the ocean provides the memory for maintaining decadal to multidecadal variability is key to climate prediction. An important question is what process could provide the observed significant time lag between the Pacific Decadal Oscillation (PDO) and the Atlantic Multidecadal Oscillation (AMO). Here, we show that the Pacific Ocean could store climate anomalies within the subtropical recirculation gyre for a decadal duration, providing a 'seeding' link between the AMO and the PDO.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Sphingosine kinases (SPHKs) are essential enzymes that catalyze the phosphorylation of sphingosine to produce sphingosine-1-phosphate (S1P), which plays pivotal roles in inflammation and immune regulation. In this study, genome-wide association analysis (GWAS) identified the gene as closely associated with the resistance of yellow drum () to . Structural prediction showed that YDSPHK1 contains a typical diacylglycerol kinase catalytic (DAGKc) domain (154-291 aa).
View Article and Find Full Text PDFFish Shellfish Immunol
October 2023
Vibrio harveyi is the primary pathogenic bacteria affecting Nibea albiflora aquaculture. In a previous phase, our laboratory intentionally exposed N. albiflora to V.
View Article and Find Full Text PDFFish Shellfish Immunol
November 2023
Galectins are a family of evolutionarily conserved lectins that contain carbohydrate recognition domains (CRDs) specifically recognizing β-galactoside. Galectin-9 plays a crucial role in various biological processes during pathogenic infections. In a previous study, galectin-9 was identified as a candidate gene for resistance to Vibrio harveyi disease in yellow drum using a genome-wide association study (GWAS) analysis.
View Article and Find Full Text PDFGalectins are proteins that play a crucial role in the innate immune response against pathogenic microorganisms. Previous studies have suggested that Galectin-3 could be a candidate gene for antibacterial immunity in the large yellow croaker . In this study, we cloned the Galectin-3 gene in the large yellow croaker, and named it LcGal-3.
View Article and Find Full Text PDFInt J Mol Sci
February 2023
Galectins are proteins that are involved in the innate immune response against pathogenic microorganisms. In the present study, the gene expression pattern of (named as ) and its function in mediating the defense response to bacterial attack were investigated. The tertiary structure of Gal-1 protein consists of homodimers and each subunit has one carbohydrate recognition domain.
View Article and Find Full Text PDFInt J Mol Sci
June 2022
Phosphoribosyl pyrophosphate synthetases (EC 2.7.6.
View Article and Find Full Text PDFInt J Biol Macromol
September 2021
Galectins are protein that participates in a variety of immune responses in the process of pathogenic infections. In the present study, a chimera galectin gene was screened from the transcriptome database of Nibea albiflora, which was named as YdGal-3. The results of qRT-PCR showed that the mRNA transcripts of YdGal-3 were ubiquitously distributed in all the detected tissues.
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