Risk prediction models for complications after flap repair surgery: a systematic review and meta-analysis.

Objective: To systematically evaluate the performance and applicability of risk prediction models for complications after flap repair and to provide guidance for building and refining models.

Methods: PubMed, Embase, Web of Science, the Cochrane Library, CNKI, SinoMed, VIP and Wanfang were searched for studies on risk prediction models for flap complications. The search period is from inception to December 28, 2024.

Near-infrared light-activated -to- isomerization of azobenzene triplet sensitization from PbS quantum dots.

Azobenzene (Azo) photoswitches have attracted significant attention for developing smart photoresponsive materials owing to their reversible light-induced isomerization between and configurations. However, it is challenging to design an Azo capable of quantitative and efficient → photoisomerization under low-energy photon irradiation, particularly near-infrared (NIR) light above 800 nm. Here, we demonstrate that → photoswitching of Azo can be achieved under 808 nm light irradiation when PbS quantum dots (QDs) are combined with carboxylated Azo (Azo1).

Clinical Reasoning Profiles in Nursing Students: Associations With Academic Performance, Encouragement for Questioning, and Access to Relevant Literature.

Background: Understanding the variability in students' clinical reasoning competence and the influencing factors is essential for developing personalized educational strategies.

Objectives: To identify distinct clinical reasoning profiles among undergraduate nursing students based on their clinical reasoning levels and determine the factors associated with membership in these identified clinical reasoning profiles.

Methods: A cross-sectional survey design was used.

Correction: Evaluation of a novel chemiluminescent immunoassay for autoantibody detection in pemphigus and bullous pemphigoid.

[This corrects the article DOI: 10.3389/fimmu.2025.

Lateral quadratus lumborum block versus transversus abdominis plane block for perioperative analgesia in patients undergoing laparoscopic colorectal cancer surgery: a randomized, controlled clinical trial.

Background: Lateral quadratus lumborum block (QLB) and transversus abdominis plane block (TAPB) have been widely used in abdominal surgeries. This study aimed to compare the intraoperative analgesic effect, hemodynamic changes and postoperative complications of the two blocks in patients undergoing laparoscopic colorectal cancer surgery.

Methods: This was a randomized controlled trial that enrolled 189 patients scheduled for laparoscopic colorectal cancer surgery.

Efficacy and safety of Kunxinning granules in patients with menopausal syndrome: a multicenter, randomized, double-blinded, and placebo-controlled trial.

Background: Menopausal syndrome is a general term for a series of physical and psychological symptoms that women experience during menopause and perimenopause, which can lead to the occurrence of a variety of diseases. Many ingredients in Kunxinning granules have been used clinically to treat menopausal syndrome. However, evidence for its effectiveness is lacking.

The chronological age at which small airway function starts to decline in a healthy Chinese population: a cross-sectional study.

Background: Small airway function naturally declines with aging. However, the precise age this decline begins in healthy Chinese individuals remains unclear. This study aimed to identify the chronological age at which small airway dysfunction (SAD) initiates and its predictors within a healthy Chinese population.

Evaluation of a novel chemiluminescent immunoassay for autoantibody detection in pemphigus and bullous pemphigoid.

Background: A novel fully automated chemiluminescent immunoassay (CLIA) has been developed to quantify autoantibodies specific for desmogleins (Dsg1, Dsg3), BP180, and BP230, key target antigens in pemphigus and bullous pemphigoid. This study aims to evaluate the diagnostic accuracy of the CLIA in diagnosing pemphigus and BP and its correlation with disease severity and clinical features.

Methods: Sera from 106 bullous pemphigoid and 54 pemphigus patients and control sera from 153 patients with other skin disease and 121 healthy volunteers were included.

Development of a Machine Learning Algorithm-Based Predictive Model for Physical Activity Levels in Lung Cancer Survivors: A Cross-Sectional Study.

Aims: To investigate the physical activity levels of lung cancer survivors, analyse the influencing factors, and construct a predictive model for the physical activity levels of lung cancer survivors based on machine learning algorithms.

Design: This was a cross-sectional study.

Methods: Convenience sampling was used to survey lung cancer survivors across 14 hospitals in eastern, central, and western China.

Impact of mHealth on Postoperative Quality of Life, Self-Management, and Dysfunction in Patients With Oral and Maxillofacial Tumors: Nonrandomized Controlled Trial.

Background: With a focus on postoperative dysfunctions that may occur after maxillofacial tumor resection and the difficulties faced during home rehabilitation, we developed a mobile health app based on nurse-patient cooperation. The app extends rehabilitation care from hospital to home with the help of artificial intelligence, Internet of Things, and other technologies, thus helping patients to better carry out their home functional rehabilitation and meet their health needs.

Objective: The primary objective of this quasi-experimental study is to evaluate the impact of the Intelligent Home Rehabilitation Care Platform on the quality of life, self-management, and functional impairment in patients with oral and maxillofacial head and neck tumors.

[The impact of oral occlusal exercises on occlusal performance of oral cancer patients following segmental mandibulectomy without simultaneous reconstruction].

Purpose: To investigate the effects of oral occlusion exercises on occlusal performance of oral cancer patients who underwent segmental mandibular resection without simultaneous reconstruction.

Methods: From October 2022 to May 2023, a total of 63 oral cancer patients who underwent segmental mandibular resection without reconstruction at the Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine were selected. They were randomly divided into control group (30 patients) and experimental group (33 patients).

Barriers to Oral Hygiene Self-Management Among Patients with Oral Cancer Treated with Radiotherapy: A Qualitative Study Using the COM-B Model.

Purpose: This study aimed to assess the factors that hinder self-oral hygiene management behaviour in patients with oral cancer undergoing radiotherapy to inform intervention programme development.

Materials And Methods: Based on the capability, motivation, and opportunity-behaviour (COM-B) model, a qualitative study was conducted involving 18 patients with oral cancer receiving radiotherapy at a tertiary hospital from March to June 2024. Semi-structured face-to-face interviews were performed to investigate the oral hygiene self-management experience of patients.

Emotions and experiences of head and neck cancer survivors returning to work: A meta-synthesis of qualitative studies.

Purpose: Head and neck cancer (HNC) survivors may face several challenges when returning to work. Although there are some qualitative studies on the return-to-work experiences of HNC survivors, a comprehensive review of these studies is lacking. This study aimed to systematically evaluate the emotions, experiences, and needs of HNC survivors returning to work.

Preventive effect of Lianhua Qingwen capsule on close contacts of seasonal influenza in residential environments: protocol for a multicenter, randomized, double-blind, placebo-controlled study.

Background: Seasonal influenza poses a high risk of death worldwide. Lianhua Qingwen (LHQW) is effective in shortening the time to symptom alleviation in patients with influenza, but there is a lack of convincing clinical trials targeting influenza prevention. This study aims to evaluate both efficacy and safety of LHQW in the preventing spread of seasonal influenza among close contacts under a cluster setting.

Combining Quantum Dots and Photochromic Molecular Switches: Next-Generation Light-Responsive Materials.

Quantum dots (QDs), with the unique merits of narrow and tunable photoluminescence (PL) wavelength, high PL quantum yield, have gained significant interest in fields such as display, solar energy conversion, bioimaging, and encrypted quantum communication. On the other hand, photochromic molecular switches (PMS) can undergo reversible interconversion between (at least) two distinct states at the molecular scale upon light irradiation. When combining QDs and PMS, the resulting hybrid systems exhibit synergistic functionalities and light responsiveness, enabling precise and reversible modulation over PL intensity/color, energy/electron transfer, and motion with high temporal and spatial resolution in a non-invasive manner.

Ear-canal lavage for curing noninvasive otomycosis: A randomized controlled trial.

Objective: Fungal infection of the external auditory canal, otomycosis, is generally a superficial, but sometimes stubborn mycotic infection that rarely involves the middle ear. We designed a randomized, controlled cohort study to analyse the treatment effect of ear canal lavage on otomycosis.

Methods: The clinical patients were divided into two groups: an irrigation group and an irrigation + local drug treatment control group.

Effects of modified starches on the dough rheological properties of wheat flour and frozen storage stability of frozen raw noodles.

Cryopreservation is typically used for the long-term storage of frozen noodles. However, the long-term cryopreservation of these high-moisture products may cause ice crystal growth on the substrate and crispy product surfaces. The aim of this study was to explore how hydroxypropyl starch (HPS), hydroxypropyl distarch phosphate, and oxidised starch improve the quality and storage stability of frozen raw noodles (FRN).

Association between the geriatric nutritional risk index and adverse post-extubation outcomes for critically ill older adults: a retrospective study.

Background And Purpose: Malnutrition commonly predicts adverse outcomes among older adults in the intensive care unit (ICU). The Geriatric Nutritional Risk Index (GNRI) is a simple and practical tool for assessing nutritional status in older adults. This study aims to explore the association between GNRI and adverse post-extubation outcomes in critically ill older adults.

Association between oral microbiome and sleep disorders in U.S. adults: analysis of NHANES database 2009-2012.

Background: The microbiome, especially the gut microbiome, contributes to the regulation, etiology, and pathogenesis of sleep disorder. However, limited evidence regarding the oral microbiome's role in sleep disorder. Therefore, this study aimed to investigate the association between sleep disorder and oral microbial diversity and whether oral microbiota is associated with all-cause mortality in people with sleep disorder.

Responsive Molecules for Organic Neuromorphic Devices: Harnessing Memory Diversification.

In the brain, both the recording and decaying of memory information following external stimulus spikes are fundamental learning rules that determine human behaviors. The former is essential to acquire new knowledge and update the database, while the latter filters noise and autorefresh cache data to reduce energy consumption. To execute these functions, the brain relies on different neuromorphic transmitters possessing various memory kinetics, which can be classified as nonvolatile and volatile memory.

Octanoic acid-rich diet alleviates breast cancer-induced bone pain via the acyl-ghrelin/NPY pathway.

Background: Breast cancer is a common malignant tumor that has a high tendency to metastasis to the bone, leading to cancer-induced bone pain (CIBP). Ghrelin can not only stimulate appetite and regulate energy balance, but also alleviate CIBP by inducing NPY expression. Octanoic acid (OA), a type of medium chain fatty acids, provides an energy substrate and promotes acylation of ghrelin.

Non-pharmacological interventions of traditional Chinese medicine in treating polycystic ovary syndrome: a group consensus.

Background: To make a group consensus about non-pharmacological interventions of traditional Chinese medicine in treating polycystic ovary syndrome based on the previous guidelines, literature, and expert viewpoints.

Methods: Organized by Chinese Integrative Medicine & Traditional Chinese Medicine Academy, Chinese Maternal and Child Health Association, China, 29 experts from 18 Chinese provinces and 2 international experts, who specialize in gynecology, obstetrics, pediatrics, endocrinology, cardiovascular, psychology, reproductive genetics, nursing, acupuncture and tuina, traditional Chinese medicine, integrative medicine, and other disciplines, discussed and revised the recommendations one by one through in-person or online communication. Each recommendation was approved by ≥90% of the experts before it could be established.

Single-cell pseudotime and intercellular communication analysis reveals heterogeneity and immune microenvironment in oral cancer.

Background: Oral cancer is one of the most prevalent malignant neoplasms globally, with its microenvironment being extremely complicated and heterogeneous with regard to distribution of different types of cells, which creates a barrier against treatment. We integrated single-cell RNA sequencing, pseudotime analysis, and intercellular communication to identify subtypes, state transitions, and interactions in the development of oral cancer and their roles in tumor progression and immune response.

Methods: Principal component analysis (PCA) followed by dimensionality reduction techniques (UMAP and t-SNE) revealed multiple populations in the single-cell data from oral cancer.

Nonlinear and nonlinear-linear hybrid interferometers using coherent and squeezed vacuum states.

Classical and quantum states working in concert play an essential role in high-precision interferometry. In this regard, coherent combined with squeezed vacuum states are the most promising candidate. Here we complement this subject by comparing nonlinear and nonlinear-linear hybrid interferometers with homodyne detection as a readout strategy.

Meta-analysis of the effect of non-pharmacological interventions on the development of dysgeusia in patients undergoing radiotherapy for head and neck squamous cell carcinoma.

This study was conducted by searching electronic databases from January 1, 2000 to August 8, 2023: Web of Science, PubMed, Cochrane Library, Embase, Scopus, Google Scholar, China Biomedical Literature Database (CBM), China National Knowledge Network (CNKI), China Science and Technology Journal Database (VIP) and Wan-fang Database were included in 14 studies with a total sample size of 1630 cases. This study conducted a meta-analysis of the literature published in recent years on the occurrence of dysgeusia in Head and neck squamous cell carcinoma (HNSCC) patients with non-pharmacological treatment, in order to provide the latest evidence-based evidence for medical staff and provide a basis for further intervention of dysgeusia in HNSCC patients. Compared with conventional care in the control group, In the experimental group, the non-pharmacological intervention reduced the score of dysgeusia [MD = - 0.