MOF Fibrous Membranes with Efficient Gas Transfer Channel for Carbon Dioxide Capture.

Metal-organic frameworks (MOFs), known for their high surface area, adjustable pore structure, and ease of functional modification, have attracted considerable interest for carbon dioxide (CO) capture. Nevertheless, their practical use is hindered by their powdered form, which results in limited mechanical strength and a reduced gas transport performance. In this study, an effective approach is presented for developing three-dimensional UiO-66-NH/polyacrylonitrile (PAN) interconnected networks to serve as efficient gas transport pathways, thereby enhancing CO adsorption capabilities.

Robotic retrohepatic inferior vena cava thrombectomy using the caudate lobectomy technique: indications and initial outcomes.

Background: Liver mobilization is essential for exposing the retrohepatic inferior vena cava (IVC) during level II-III robot-assisted IVC thrombectomy (RA-IVCT), but complex cases present significant challenges with a high risk of severe complications. This study aimed to evaluate the safety and feasibility of caudate lobectomy in facilitating retrohepatic IVC exposure in these complex cases.

Methods: Sixteen patients with complex level II-III IVC tumor thrombus (IVC-TT) underwent RA-IVCT with caudate lobectomy in our institution from January 2021 to November 2023.

The role of ASS1 in mouse embryonic stem cell differentiation into mesendoderm lineages.

Background: Argininosuccinate synthase (ASS1) is a pivotal enzyme involved in the urea cycle, playing a crucial role in aspartate catabolism, arginine and nitric oxide biosynthesis. These biological processes are crucial for the growth and development of mammals. However, the functions of urea cycle-related genes in mouse embryonic stem cells (mESCs) remain largely unclear.

A novel blocker displacement qMSP assay for DNA methylation analysis at single-base resolution.

Accurate quantification of DNA methylation at single-CpG resolution remains a challenge for conventional qMSP, which typically lacks the specificity to discriminate solitary methylated sites. Here, we present a novel blocker displacement qMSP (BD-qMSP) assay that integrates a rationally designed blocker oligonucleotide to suppress unmethylated sequences while enabling robust amplification of single methylated CpGs. Through systematic optimization of blocker design, primer/probe modification, and annealing conditions, BD-qMSP achieved high discrimination efficiency with a detection limit as low as 0.

Single-Center Experience of Robot-Assisted Nephrectomy and Venous Tumor Thrombectomy: Indications, Surgical Strategies, and Long-Term Outcomes.

To introduce the indications and surgical strategies of robot-assisted nephrectomy and venous tumor thrombectomy (RA-N-VTT) and to assess the long-term outcomes in a high-volume, single-center setting. We retrospectively enrolled 309 patients with renal tumors and venous tumor thrombus who underwent a robotic procedure in our center between June 2013 and December 2023. To better define the indications and surgical strategies for RA-N-VTT, we proposed the Chinese People's Liberation Army General Hospital (PLAGH) classification system, incorporating three modifications to the Mayo Clinic classification system.

Role of the PomiR171n-PoUGT89B2 module in regulating the petal senescence of tree peony.

Tree peony is a traditional and popular ornamental flower. However, its short and concentrated flowering period restricts the development of the tree peony industry. In this study, the function of the PomiR171n-PoUGT89B2 combination related to senescence regulation was analyzed, using Paeonia ostii 'Fengdan' (P.

Research on the Influence Law and Mechanism of Regenerated Ceramic Tile Form and Replacement Rate on the Mechanical Properties of Ultra-High-Performance Concrete.

Ultra-high-performance concrete (UHPC) has gained widespread application across various domains owing to its superior properties. Nevertheless, the high cement content and associated costs present challenges, including significant shrinkage of the cement matrix and economic considerations. Using industrial by-products or waste to replace some raw materials is one of the effective solutions.

Effect of supplementation with -Citrulline on rumen microbiota structure, plasma metabolites, reproductive hormones, and antioxidant capacity of Hu ewes.

Citrulline (Cit), a non-essential amino acid, is characterized by its unique extrahepatic metabolism, which significantly enhances the bioavailability of arginine metabolism in tissues. This study investigated the impact of -Cit supplementation on ruminal microbiota composition, plasma metabolites, reproductive hormones, and antioxidant capacity in Hu ewes. Sixty non-pregnant Hu ewes, similar in age and parity, with an average body weight of 47 ± 5.

Omni-Explorer: A Rapid Autonomous Exploration Framework With FOV Expansion Mechanism.

Autonomous exploration is a fundamental challenge for numerous applications of mobile robots. Traditional methods often lead to impractical and discontinuous trajectories, which may substantially deteriorate the exploration time. In this work, we propose a rapid autonomous exploration framework with a field-of-view (FOV) expansion mechanism.

Evaluating Postoperative Hidden Blood Loss in Proximal Femoral Nail Anti-Rotation Fixation: The Role of Greater Trochanter Fracture Comminution.

BACKGROUND Intertrochanteric fractures can be managed using insertion of a proximal femoral nail anti-rotation (PFNA) intramedullary nail inserted into the femur. The helical blade used with the PFNA technique has the advantage of less bone removal and good biomechanical properties, but significant hidden blood loss (HBL) can occur. This study compared postoperative HBL in 219 elderly patients with intertrochanteric fractures using PFNA fixation, stratified by greater trochanter comminution status (comminuted vs non-comminuted).

Case Report: Systemic contact dermatitis caused by benzalkonium chloride in a family (a child and parents).

Background: Systemic contact dermatitis (SCD) occurs due to re-exposure to sensitizing agents via systemic routes, often triggered by drugs, metals, and food additives. Benzalkonium chloride, a cationic surfactant in different household products, can also induce allergic reactions.

Case Presentation: An 11-year-old girl and her parents presented to our outpatient clinic with erythematous, pruritic plaques and scaling.

Unraveling R-loops: The hidden drivers of inflammation and immune dysregulation.

An R-loop is a complex nucleic acid structure consisting of an RNA-DNA hybrid and an associated single-stranded DNA. This structure plays an important role in many biological processes, including gene regulation, DNA replication, and maintenance of genome stability. Under physiological conditions, the R-loop is in a dynamic balance of generation and decomposition, which is a complex process involving multiple mechanisms of its formation, clearance, and regulation.

The multifaceted biomimetic titanium implant promotes bone integration with sequential antibacterial and immune modulation properties.

Titanium (Ti) and its alloy implants often face issues such as insufficient tissue adhesion and vulnerability of the bio inert surface. Given that the long-term stability of implants depends on their perfect integration with the surrounding tissues to withstand various environmental stresses, current research mainly focuses on mimicking the structure of the extracellular matrix. The aim is to promote bone tissue formation through regulation of the immune response by metal ions, thereby enhancing the effectiveness of tissue integration.

Specific distinguishing between miRNA and pre-miRNA by blocker displacement SMOS-qPCR.

MicroRNAs (miRNAs) play crucial roles in various biological processes, and their dysregulation is associated with numerous diseases. Accurate quantification of mature miRNAs is essential for their use as biomarkers. However, distinguishing between mature miRNAs and pre-miRNAs remains challenging.

Joint technique "parallel peptide synthesis & de novo sequencing" development for the structure verification and high-throughput activity screening of biological peptides from sea cucumber (Stichopus japonicus) intestinal hydrolysate.

This study introduces a novel joint technique combining "parallel peptide synthesis" and "de novo sequencing", which facilitates the high-throughput screening and structure validation of biological peptides derived from food and traditional Chinese medicine (TCM). Sea cucumber (Stichopus japonicus) was used as a model organism, undergoing simulated gastrointestinal digestion followed by de novo sequencing to predict potential peptides. Subsequently, cost-effective filter pipette tips were innovatively employed as parallel reaction vessels, enabling efficient peptide synthesis through the microfluidic flow of amino acid solutions over the loaded resin.

Non-Target Metabolomics Reveals Changes in Metabolite Profiles in Distant Hybrid Incompatibility Between sect. and .

Peonies are globally renowned ornamental plants, and distant hybridization is a key method for breeding new varieties, though it often faces cross-incompatibility challenges. The metabolic mechanisms underlying the crossing barrier between tree peony ( sect) and herbaceous peony () remain unclear. To identify key metabolites involved in cross-incompatibility, we performed a cross between 'Fengdanbai' (female parent) and 'Red Sara' (male parent) and analyzed metabolites in the stigma 12 h after pollination using UPLC-MS.

Regulation of synaptic function and lipid metabolism.

Synapses are key structures involved in transmitting information in the nervous system, and their functions rely on the regulation of various lipids. Lipids play important roles in synapse formation, neurotransmitter release, and signal transmission, and dysregulation of lipid metabolism is closely associated with various neurodegenerative diseases. The complex roles of lipids in synaptic function and neurological diseases have recently garnered increasing attention, but their specific mechanisms remain to be fully understood.

Bromide as Noninnocent Ligand to Iron Tames Fenton Chemistry for Chemoselective Nondegrading Oxidation.

It has long been the chemistry dogma that the nitrogen-based ligand of iron complexes determines the redox reactivity; tetra- and/or pentadentate nitrogen-based ligand (N-ligand: PDP, porphyrin, N4Py) enables chemo-selective oxidation through high-valent iron species (Fe═O), while bi- and/or tridentate N-ligand leads to the generation of highly reactive oxygen species (ROS) (i.e., hydroxyl radical) via a Fenton chemistry pathway.

Efficient Screening of α-Glucosidase Inhibitory Peptides From Seahorse Through the Innovative Joint Technique: De Novo Sequencing and Parallel SPOT Synthesis.

In this research, de novo sequencing was innovatively combined with parallel SPOT synthesis for the efficient screening of biological peptides from TCM or seafood: seahorse with synergistic antioxidant and α-glucosidase inhibitory activities, which is promising for postprandial hyperglycemia management. Gastrointestinal digestion mimic and de novo sequencing were sequentially carried out to predict new peptides from seahorse. After bioinformatic analysis using Peptide Ranker, 82 peptides were eventually synthesized by efficient parallel SPOT technique, and Ser-Val-Try-Leu-Gly-Gly-Ser-Leu-Leu (SVWLGGSLL) was screened out as the most efficient peptide with synergistic antioxidant (DPPH radical scavenging activity of 77%) and α-glucosidase inhibitory activity (IC = 0.

Interspecific Hybridization Barrier Between and .

is a threatened and valuable germplasm in the cultivated tree peony gene pool, with distinctive traits such as tall stature, pure yellow flowers, and scarlet foliage in autumn. However, the crossability barrier limits gene transfer from to cultivated tree peony. Therefore, our study investigated the reasons for the lack of crossability between and 'Fengdan'.

Uranium immobilization via sulfur-modified Fe nanoparticles: U(VI) trapping kinetics and long-term stability evaluation.

The modification of nanoscale zero-valent iron (nZVI) by loading or incorporating sulfur into the iron crystal lattice can augment their efficacy in the removal of hydrophobic contaminants from wastewater. Nevertheless, the reactivity of sulfur-embedded nZVI (SnZVI) in immobilizing hydrophilic uranyl ions and the long-term stability of the sequestered uranium has received little attention. This study employed NaSO to modify the nZVI with different S/Fe molar ratios (0.

Serum direct SMOS-qPCR: a fast approach for miRNAs detection.

This study presents a novel method for direct amplification of multiple microRNAs (miRNAs) from serum samples using Sensitive and Multiplexed One-Step RT-qPCR (SMOS-qPCR). The technique eliminates the need for separate miRNA extraction and purification steps, offering a streamlined approach for non-invasive early disease diagnosis. We optimized reaction conditions, including serum treatment methods and PCR system volumes, to enhance interference resistance and detection sensitivity.

Hierarchical Fibrous Metal-Organic Framework/Ionic Liquid Membranes for Efficient CO/N Separation.

The structural diversity and chemical functionality of metal-organic frameworks (MOFs) render them promising candidates for CO adsorption and separation. However, their applications are often restricted by their intrinsic fragility and decreased processability. Herein, a hierarchical fibrous MOF/ionic liquid (IL) membrane was constructed by assembling well-ordered ZIF-8 nanounits with an encapsulated IL along the polyimide (PI) fibers.

Effects of Novaluron Exposure on the Oviposition and Expression of Ovarian Development Related Genes in Silkworm, (Lepidoptera: Bombycidae).

(Lepidoptera: Bombycidae) is an important economic insect, which mainly feeds on mulberry leaves and is widely used in many research fields. The growth and development of silkworm larvae are easily affected by the use of chemical insecticides such as novaluron, a benzoylurea insecticide. However, the effect of novaluron exposure on the reproduction of silkworms has not yet been studied.