A simple and efficient synaptic device based on MoTeO/MoTeheterojunction treated with oxygen plasma.

Two-dimensional (2D) materials are widely used in designing and fabricating artificial optoelectronic synapses due to their atomic-level thickness, ultra-high carrier mobility, strong light-matter coupling, and extreme sensitivity to electrostatic modulation. In this work, we present an artificial synapse based on a MoTeO/MoTeheterojunction. Oxygen vacancy defects are introduced on the MoTesurface via oxygen plasma treatment, enabling charge transfer and storage in the channel through defect utilization.

Near-Infrared Electroluminescence from Ambipolar Transistors Built on sp-Functionalized Carbon-Nanotube Networks.

We demonstrate room-temperature, near-infrared electroluminescence (EL) from networks of sp-functionalized (6,5) single-walled carbon nanotubes (SWCNTs) using ambipolar transistors with sub-10 μm channels. EL efficiency dependences on drain current and channel length are investigated, giving insights into the carrier recombination in SWCNT networks. EL from free and localized excitons are strongly limited by trap-assisted Shockley-Read-Hall (SRH) recombination; high emission efficiency can be achieved in short channels down to 2 μm with the alleviation of SRH recombination.

Brachyury-Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment.

Extracellular matrix (ECM) metabolic disorders and the establishment of inflammatory microenvironment are the primary pathological alterations associated with intervertebral disc degeneration (IVDD). The inflammatory microenvironment promotes ECM degradation, further exacerbating the vicious cycle of nucleus pulposus (NP) degeneration. This study introduces the mRNA encoding a novel therapeutic transcription factor, Brachyury (Bry), into nucleus pulposus cells (NPCs) using an injectable microsphere system composed of biomimetic GelMA/Fucoidan (FU) dual-component hydrogel (GF) and surface chemically grafted lipid nanoparticles (LNP) (BLNP@GF).

Gradient Desolvation-Diffusion Kinetic Layer Promoters for Low-Temperature Dendrite-Free Zn Metal Batteries.

Aqueous zinc metal batteries have emerged as strong candidates for large-scale energy applications, but they are inhibited by significant dendrite growth resulting from corresponding depressive desolvation-diffusion kinetics. Herein, the strategy of gradient desolvation-diffusion kinetics is proposed by constructing an organic-inorganic layer on the zinc anode for increasing robust mechanical properties and strengthening ion/atom transport. The electron-insulative polymer layer effectively prevents interfacial electron contact from side reactions, and the phase-transformed Sn and ZnF layer also promotes Zn transport with lower barrier, as demonstrated by electrochemical and theoretical simulations.

Reversible formation and control of linear conjugation in polymers.

The emergence of organic semiconductors has laid the foundation for the field of plastic electronics. Controlling π-conjugation by designing proper conjugated moieties is one of the commonest strategies for achieving desired semiconducting properties in conjugated materials. Despite significant advancements in the field, the reversible formation of extended conjugation to in situ switch the nature of macromolecules between semiconductors and insulators remains elusive.

Enhanced CuZn Coating on Carbon Fibers Through C─O─Cu Bridging Bond for Homogeneous Zinc Deposition in Zinc-Iron Flow Batteries.

Zinc-based flow batteries (ZFBs) are promising for grid-scale energy storage due to their high energy density, low cost, and safety. However, uneven zinc plating, dendrite formation, and limited areal capacity in Zn anodes remain significant challenges. To address these issues, carbon felt (CF) electrodes are functionalized with oxygen-containing groups to form stable C─O─Cu bridging bonds, which enhance the adhesion of CuZn to CF.

Multifunctional Sr/Zn Co-Doped Mesoporous Silica Nanoparticles in Injectable Hydrogel for Ameliorating Osteoporotic Osseointegration.

Developing advanced biomaterials with controllable nanostructures and biological multifunctionality is highly promising in biomedical fields. In this study, novel Sr/Zn co-doped mesoporous silica nanoparticles (MSNs) are fabricated using a designated substitution and etching method. The obtained SrZn-MSNs possess unique hollow mesoporous structures, round spherical morphology, high specific surface areas, and suitable pore sizes.

Ligand-functionalized metal-organic framework-based evaporator for synchronous freshwater production and agricultural wastewater remediation.

Solar-driven interfacial evaporation has been regarded as a promising method to alleviate water shortage. However, the organic contaminants are commonly accumulated on the evaporator during the evaporation process, which not only reduces the service life of the evaporator but also causes more serious pollution. Herein, a desalination-catalysis-irrigation integrated wood-based evaporator was presented by introducing cyano groups (-CN) in a metal-organic framework (MOF) system (M-NH-CN/wood).

Hydroxysafflor yellow A promotes the proliferation and differentiation of endogenous neural stem cells with neural regenerative effects in ischemic stroke.

Background: Ischemic stroke induced irreversible damage or loss of neurons, severely causing high death rates. Natural medicine has rapidly risen for stroke therapy. Given the activation of neural cells, it is crucial to reveal the neuroregulation and molecular mechanisms of natural medicine for developing effective therapeutical approaches for stroke.

Fibre Computer Enables More Accurate Recognition of Human Activity.

The advancement of fibre electronics is crucial for developing wearable smart textiles. However, traditional single-function fibres are typically limited to basic sensing and data collection capabilities, lacking effective computational and multimodal signal processing abilities, thus significantly restricting their potential in human activity recognition. Recently, Gupta et al.

Bio-inspired mid-infrared neuromorphic transistors for dynamic trajectory perception using PdSe/pentacene heterostructure.

Mid-infrared (MIR) intelligent sensing technology is essential for precise identification and tracking for dynamic target detection in challenging and low-visibility environments. However, existing MIR vision systems based on traditional von Neumann architecture face significant delays and inefficiencies due to the separation of sensing, memory, and processing units. Neuromorphic motion devices offer better tracking capabilities, but most studies are limited to the near-infrared spectrum.

An Engineered Multivalent TMV Nanodisk Platform for Modulating Integrin Clustering and Cell Signaling.

Clustering of cell-surface receptors is essential for initiating signaling cascades and regulating cellular functions. Multivalent ligands with high receptor affinity offer powerful tools for manipulating these processes and advancing therapeutic strategies. However, designing easily modifiable, stable, and uniformly structured multivalent ligands remains a significant challenge.

3D-printed molecule-recognized photoelectrochemical sensing platform by expansion-flow-induced vertical alignment of graphene nanosheets for urea assay.

Channel-aligned modulation of a molecule-recognized photoelectrode to generate superior light-absorbing yet high-level analyte-adsorbing is pivotal but challenging for implementing highly sensitive and selective photoelectrochemical sensing. Herein, we demonstrated an innovative expansion-flow-modulated direct ink writing (DIW) 3D printing coupled with molecular imprinting technology for controllably building a microlattice-shaped photoelectrochemical sensor, with multiscale well-interconnected aligned channels created by vertically aligned arrangement of molecule-recognized photoactive graphene (G) nanosheets within printed filaments and regularly orthogonal layer-by-layer assembly of filaments. The unique architectural merit enabled rapid analyte diffusion and ready light spreading to photoactive and specific recognition sites located at all channel walls, thus endowing the sensor with a combined feature of prominent light absorption and analyte trapping.

Inhibition of tumor-intrinsic NAT10 enhances antitumor immunity by triggering type I interferon response via MYC/CDK2/DNMT1 pathway.

Posttranscriptional modifications are involved in cancer progression. However, the function and regulatory mechanism of mRNA acetylation modification remains largely unknown. Here, we discover an unexpected role of N4-acetylcytidine (ac4C) RNA acetyltransferase NAT10 in reshaping the tumor immune microenvironment.

The hotspots and publication trends in glioblastoma and CAR-T immunotherapy: A bibliometric analysis.

In recent years, chimeric antigen receptor T cell (CAR-T) immunotherapy has made considerable progress in the treatment of glioblastoma. The aim of this study was to comprehensively explore the prospects and future trends of CAR-T immunotherapy for glioblastoma through systematic bibliometric analysis. Publications pertaining to glioblastoma and CAR-T immunotherapy from 2008 to 2024 were extracted from the Web of Science Core Collection.

Bioresorbable Composite Polymeric Stents: Alleviating Deployment Damage and Maintaining Significant Mechanical Properties.

The latest-generation Poly(L-lactic acid) (PLLA) based fully bioresorbable stents (BRS) are facing a grave challenge due to their higher clinical risk of post-implantation. There is consensus that the strut thickness of BRS far exceeds that of metal stents; this is the main reason for the poor clinical outcomes. Therefore, overcoming the gap in mechanical properties between PLLA and metal, and effectively reducing the strut thickness of BRS without sacrificing mechanical properties, is a research priority.

Programming the Valence and Orientation of Anisotropic Nanoparticles via Three-Dimensional DNA Ligand Encoding.

The geometric nature of anisotropic nanoparticles (NPs) gives rise to directional variations in their physicochemical properties, making the characteristics of their assemblies highly tunable by manipulating their three-dimensional (3D) spatial configurations. Surface modification with DNA ligands, which creates molecular recognition between NPs, offers a practical approach for self-assembling NPs into customized nanostructures with emergent collective properties. However, the regioselective modification of DNA ligands on the complex 3D surface of anisotropic NPs to create specific and directional bonds remains challenging.

Prospect of Cascade Catalysis in Magnesium-Sulfur Batteries from Desolvation to Conversion Reactions.

Magnesium-sulfur (Mg-S) batteries have the advantages of high volumetric energy density, intrinsic safety, and low cost of anode and cathode materials. However, current obstacles that preventing practical applications of Mg-S batteries are reflected in the sluggish reaction kinetics of insulative sulfur cathode, designs of compatible electrolytes, and surface optimization of Mg anode against passivation. Regarding the sulfur cathodes, the inherent low conductivity, high volumetric changes, and polysulfide shuttling always result in depressive capacity and utilization.

Electrostatic Field Modification Enhances the Electrocatalytic Oxygen Evolution Reaction Stability of CoFeO Catalysts.

Enhancing the stability of oxygen evolution reaction (OER) catalysts is a critical challenge for realizing efficient water splitting. In this work, we introduce an innovative approach by applying an electric field during the annealing of a CoFeO/C catalyst. By controlling the electric field strength (100 mV) and treatment duration (1 h), we achieved dual optimization of the catalyst's microstructure and electronic environment, resulting in a significant improvement in catalytic stability.

Rapid Synthesis of Fast-Charging TiNbO for Lithium-Ion Storage via Ultrafast Carbothermal Shock.

The development of fast-charging lithium-ion batteries urgently requires high-performance anode materials. In this paper, through an ultrafast carbothermal shock (CTS) strategy, titanium niobium oxide (TiNbO, TNO) with an optimized structure was successfully synthesized within 30 s. By regulating the synthesis temperature to 1200 °C, the TNO-1200 material was obtained.

Dual-Anion Reinforced Cathode-Electrolyte Interphase for Stable Conversion-Type Cathode.

Pyrite FeS, recognized as a promising conversion-type cathode material for high-energy-density batteries, encounters a rapid decline in capacity due to the polysulfide shuttle effect. To tackle these challenges, this study introduces a nonflammable locally concentrated ionic liquid electrolyte (LCILE) composed of lithium bis(fluorosulfonyl)imide (LiFSI), 1-vinylpropyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (AMImTFSI), and 1,1,2,2-tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether (TTE). This electrolyte manifests a tailored solvation structure with FSI-TFSI dual-anion-dominated aggregates (AGGs), which effectively mitigates the shuttle effect of polysulfides and fosters the formation of a robust dual-anion-derived cathode-electrolyte interphase (CEI) on the FeS cathode.

Electrically Pumped Valley Emitter in Transition Metal Dichalcogenides with Magnetic Manipulation.

Optical pumping has been extensively employed as a straightforward and efficient method for the investigation of excitonic effects in 2D transition metal dichalcogenides (TMDCs). However, the challenge of achieving well-matched resonant excitation makes it difficult to conduct a comprehensive and rigorous comparative study across different TMDCs systems. In this work, electrical pumping is utilized on quantum well structures of TMDCs, enabling equivalent carrier injection with similar kinetic energy while effectively mitigating the effects of non-resonant excitation.

Multifunctional interface engineering enables efficient and stable inverted organic photovoltaics.

Compared to conventional (p-i-n) organic photovoltaics (OPVs), inverted (n-i-p) OPVs hold promise for future commercial applications due to their advantages in printing process compatibility and environment robustness. The current bottleneck lies in the efficiency and light stability, which is closely related to the defects and the photocatalytic reactivity of metal oxides transport layer. This comment summarizes the recent progress on inverted OPV and outlines potential solutions to surmount the hurdles before the technology can be put into production.

Edge-Oriented Surface Plasmons and Out-of-Plane Phonon-Coupling-Manipulated Davydov Splitting in WS Flakes with Nonexciton Resonance Excitation under Ambient Conditions.

Two-dimensional (2D) materials with van der Waals (vdW) interactions have driven significant advancements in electronics, optics, and materials science. Controlling and understanding interlayer interactions are crucial to expanding their potential applications. Davydov splitting, which is associated with phonon-electron-exciton-coupling dynamics, offers a method to investigate and assess interlayer interactions in 2D vdW materials.

Dimensional reduction in CsAgBiBr enables long-term stable Perovskite-based gas sensing.

Halide perovskite gas sensors have a low gas detection limit at room temperature, surpassing the performance of traditional metal oxide chemiresistors. However, they are prone to structural decomposition and performance loss due to the lack of coordination unsaturated surface metal ions and sensitivity to environmental factors such as water, oxygen, heat, and light. To address this issue, we present a general strategy: replacing the cation Cs in inorganic perovskite CsAgBiBr with long-chain alkylamines.