NgBeB : Binding of Noble Gas Through Both Cationic Beryllium and Anionic Boron Centers.

Quantum chemical calculations have been performed to investigate the structure, stability, and bonding in noble gas (Ng) bound BeB complexes. The present results show that BeB , a charge-separated [Be][B][Be] cluster, can employ both its cationic Be center and anionic B center to bind Ng atoms. It can bind a total of seven Ng atoms, resulting in the formation of a highly symmetric (Ng)Be(Ng)B complex, having D point group.

Adsorbed oxygen dynamics at forced convection interface in the oxygen evolution reaction.

The oxygen evolution reaction is a prevalent anodic reaction in electrocatalytic processes. Modulation of adsorbed oxygen (*O) at the electrochemical interface is an effective means to reduce the overpotential of the oxygen evolution reaction. However, the contribution of various *O conversions to the overpotential remains unclear.

Defect-mediated high loading metal single-atom catalysts direct oxygen reduction reaction selectivity to HO production.

Transition metal single-atom catalysts (TM-SACs) have emerged as promising electrocatalysts for the two-electron oxygen reduction reaction (2eORR) due to their exceptional atomic utilization efficiency and tunable electronic structures. Nevertheless, the practical application of TM-SACs is constrained by their relatively low metal loading, which adversely affects their catalytic performance. Herein, we developed a universal defect-mediated strategy to fabricate TM-SACs with high metal loading.

A Resource for Exploring Regional Diversity in the Male Rat Brain Synaptic Proteome.

The functional complexity of the mammalian brain is rooted in the diverse protein composition of synapses across distinct regions. To address the need for a detailed molecular understanding of this regional diversity, we generated the first comprehensive proteomic map of synaptosomes from six key rat brain regions: anterior cortex, posterior cortex, hippocampus, striatum, olfactory bulb, and cerebellum. Using high-resolution quantitative proteome and the Percoll density gradient ultracentrifugation, we identified 3,440 proteins and yielded high synaptic enrichment (60.

Single LED visible light positioning scheme based on intelligent reflecting surfaces.

Visible light positioning (VLP) systems have gained attention for their ability to operate without additional infrastructure. However, most positioning schemes rely on multiple LEDs, which presents a considerable challenge in scenarios where only a single-light-source is available. To address this issue, this work proposes using intelligent reflective surfaces (IRS) as virtual light sources for VLP.

Robust A-site Cation Engineering for Stable 2D High-n Tin Perovskite Homologs with Bridged Lasing Emission Gaps.

Two-dimensional high-n halide perovskites (e.g., n  = 3) offer a unique platform for stable, efficient optoelectronics by synergizing improved stability with bulk-like carrier transport.

Clinicopathological analysis of hyalinizing clear cell carcinoma in the head and neck.

Objective: To study clinicopathological features and differential diagnosis of hyalinizing clear cell carcinoma in the head and neck.

Methods: A retrospective analysis was performed patients with hyalinizing clear cell carcinoma in the head and neck, who underwent surgical resection in Beijing Tongren Hospital affiliated to Capital Medical University from January 2014 to May 2024. The clinical features of HCCC were analyzed by computed tomography and magnetic resonance imaging.

Common bias-digital subcarrier multiplexing scheme for integrated sensing and communication in short-reach optical transmission systems.

The integration of sensing and communication (ISAC) based on optical fibers has been a key enabling technique to achieve high-speed communication while ubiquitous sensing. In this paper, to ensure the coexistence of communication signal and sensing signal in low-cost optical access networks i.e.

Resilience of Pediatric Healthcare Services in an Urban Hospital in China During the COVID-19 Pandemic in Late 2022.

The abrupt relaxation of COVID-19 control measures in China in December 2022 created acute pressures on paediatric healthcare services. We retrospectively evaluated patient visits, healthcare staffing and hospitalisation costs at Wuxi Children's Hospital, a tertiary paediatric centre. Despite over 40% staff absenteeism due to COVID-19, essential paediatric services remained operational through flexible staffing and workflow adaptations.

Regulating the donor number of solvents for long-cycle anode-free lithium metal batteries.

Anode-free lithium-metal batteries (AFLMBs) are one of the up-and-coming high-energy-density battery systems because they eliminate the need for conventional graphite electrodes or excess lithium metal anodes (LMAs). However, AFLMBs have serious problems of low coulombic efficiencies (CEs) and poor cycle stability. Herein, this study proposes a local high-concentration electrolyte (LHCE) based on donor number (DN) modulation, which achieves stable dissolution of LiNO and an anion-enhanced solvation structure through the synergistic action of a high DN solvent (tetraglyme, G4) and an ultra-low DN diluent (1,1,2,2-tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether, TTE).

Development and validation of a predictive model for in-hospital mortality in patients with coronary heart disease and renal insufficiency.

Background: Coronary Heart Disease (CHD) with renal insufficiency is a significant global health issue. This study aimed to develop and validate a predictive model for in-hospital mortality to enable early risk identification in these patients.

Methods: We analyzed data from 11,830 CHD patients with renal insufficiency treated at Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China (1994-2023).

Prediction of gastrointestinal hemorrhage in cardiology inpatients using an interpretable XGBoost model.

Gastrointestinal bleeding (GIB) occurs more frequently in cardiovascular patients than in the general population, significantly affecting morbidity and mortality. However, existing predictive models often lack sufficient accuracy and interpretability. We developed an interpretable and practical machine learning model to predict the risk of GIB in cardiology inpatients.

Association of ambient air pollutants with maternal thyroid hormones during the entire pregnancy.

This study aims to investigate associations between PM, PM, and NO and maternal thyroid hormones. We investigated 443 pregnant women in Zhejiang, China with repeated examinations of serum thyroid hormones at 10, 17, and 32 weeks. Individual exposures to ambient air pollution were retrospectively calculated by inverse distance weighting interpolation.

Development of a prediction model for hemorrhagic transformation after intravenous thrombolysis in patients with acute ischemic stroke: a retrospective analysis.

Background: Hemorrhagic transformation (HT) is a serious and common complication following intravenous thrombolysis in acute ischemic stroke (AIS), often leading to worsened outcomes. Identifying risk factors for HT and developing accurate predictive models are essential for improving patient management and prognosis.

Methods: A retrospective analysis was performed on 159 patients with acute ischemic stroke who received intravenous thrombolytic therapy at Hubei Third People's Hospital Affiliated to Jianghan University School of Medicine from March 2019 to July 2022.

Genome-Wide Identification of Wheat Gene Resources Conferring Resistance to Stripe Rust.

Stripe rust, caused by f. sp. (), threatens global wheat production.

Near-Infrared Electroluminescence from Ambipolar Transistors Built on sp-Functionalized Carbon-Nanotube Networks.

We demonstrate room-temperature, near-infrared electroluminescence (EL) from networks of sp-functionalized (6,5) single-walled carbon nanotubes (SWCNTs) using ambipolar transistors with sub-10 μm channels. EL efficiency dependences on drain current and channel length are investigated, giving insights into the carrier recombination in SWCNT networks. EL from free and localized excitons are strongly limited by trap-assisted Shockley-Read-Hall (SRH) recombination; high emission efficiency can be achieved in short channels down to 2 μm with the alleviation of SRH recombination.

Gram-Scale Ammonia Synthesis via Electrochemical Nitrate Reduction Using Enzyme-Inspired Dual-Atomic Cu Catalyst.

The potential application prospects of green electricity-driven electrocatalytic nitrate reduction (NO₃RR) technology for the production of valuable ammonia have garnered widespread attention. However, designing electrocatalysts with remarkable activity and stability for the NO₃RR to realize gram-level ammonia production remains a significant hurdle in terms of practical application. In nature, the synergistic effect of the dual-site copper of nitrite reductase promotes the substrate adsorption and protonation, achieving efficient conversion of nitrite.

Lymphatic Metastasis of Esophageal Squamous Cell Carcinoma: The Role of NRF2 and Therapeutic Strategies.

The lethality of esophageal squamous cell carcinoma (ESCC), and other epithelial cancers, is primarily due to its aggressive nature and frequent lymphatic metastasis, both of which impact prognosis. In this review, we explore the underlying molecular mechanisms of ESCC lymphatic metastasis, specifically, the functional role of NRF2 and therapeutic strategies. Current data suggest that NRF2 hyperactivation (NRF2) may promote lymphatic metastasis of ESCC by affecting the extracellular matrix (ECM), epithelial-mesenchymal transition (EMT), lymphangiogenesis, immune evasion, metabolic programming, and Hippo signaling.

Schottky MSM-Structured Tribovoltaic Nanogenerator Enabling Over 25,000 nC Charge Transfer via Single Droplet Impact.

Using water droplets to generate electricity is an attractive approach for addressing the energy crisis. However, achieving high charge transfer and power output in such systems remains a major challenge. Here, a tribovoltaic nanogenerator (TVNG) is developed based on a specially designed Schottky metal-semiconductor-metal (MSM) structure.

Ultra-low Cu(I) loading achieving ultra-high fouling-resistance and decontamination performance in a self-cleaning CuO/TiCT@PVDF catalytic membrane integrated system.

Engineering a catalytic and hydrophilic membrane integrated system holds significant environmental implications for fouling-resistant and efficient water purification. The heterojunction CuO/TiCT was successfully synthesized by leveraging the specific interactions between the terminal active groups of MXene and CuO, effectively addressing the limitations of the catalytic membrane's performance due to low-dose doping, and enhancing its catalytic activity and hydrophilicity. Here we report a ultra-low Cu(I) loading that achieves ultra-high fouling-resistance and decontamination performance in a self-cleaning CuO/TiCT@PVDF catalytic membrane integrated system.

Preventive and controlling effects of -acetylneuraminic acid in regulating glucose and lipid metabolism disorders the gut-liver axis in high-fat diet mice.

A high-fat diet may disrupt sialic acid homeostasis indirectly by altering the gut microbiota and metabolic pathways. Sialic acid interventions have immune-regulatory effects and can improve gut health, but their impact on glucose and lipid metabolism disorders, both before and after obesity induced by a high-fat diet, remains unclear. This study used two models: a preventive experiment (intervention during high-fat diet feeding) and a control experiment (intervention after obesity induction).

Evaluation of the Temporal Characteristics of Ultrafast Imaging Methods Using Continuous Chirped Pulse Illumination.

Ultrafast imaging based on chirped pulse illumination has opened new frontiers, offering a frame rate beyond 1 Tfps for the acquisition of multiple frames in a single-shot. However, the temporal resolving capability is implicitly influenced by parameters in stages of pulse illumination and data acquisition. This study delivers a mathematical model to produce a precise investigation, sorting the dominating factors, including the illumination pulse's bandwidth λFWHM, dispersive propagation length , and framing module's spectral resolution Δλ.

Inverse reinforcement learning for discrete-time linear systems based on inverse optimal control.

This paper mainly deals with inverse reinforcement learning (IRL) for discrete-time linear time-invariant systems. Based on input and state measurement data from expert agent, several algorithms are proposed to reconstruct cost function in optimal control problem. The algorithms mainly consist of three steps, namely updating control gain via algebraic Riccati equation (ARE), gradient descent to correct cost matrix, and updating weight matrix based on inverse optimal control (IOC).

Per- and polyfluoroalkyl substances mixture impairs intestinal barrier function through microbiota-derived 21-deoxycortisol and cortisol metabolism dysregulation.

Per- and polyfluoroalkyl substances (PFASs) are persistent environmental pollutants linked to various health risks, including intestinal disorders. However, the effect of real-world PFASs mixture on intestinal health remains unclear. Therefore, this study aimed to investigate the effects of a PFASs mixture by mimicking the exposure composition in a population on intestinal homeostasis in rats.

INHBA macrophages and Pro-inflammatory CAFs are associated with distinctive immunosuppressive tumor microenvironment in submucous Fibrosis-Derived oral squamous cell carcinoma.

Transcriptomic and metabolic profiles of tumor cells and stromal cells in oral squamous cell carcinoma (OSCC)-derived from oral submucosal fibrosis (OSF) (ODSCC) have been reported. However, the complex intercellular regulatory network within the tumor immunosuppressive microenvironment (TISME) in ODSCC remains poorly elucidated. Here, we utilized single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) data from GEO database and multiple immunofluorescence staining (mIF) to reveal distinctive TISME of ODSCC.