[Ultrasound-guided closed reduction and internal fixation using Kirschner wire for the treatment of olecranon fractures of the ulna in children].

Objective: To investigate the clinical efficacy and safety of ultrasound-guided closed reduction and internal fixation using Kirschner wire for the treatment of olecranon fractures of the ulna in children.

Methods: Between January 2019 and January 2021, 13 children with olecranon fracture were treated with ultrasound-guided closed reduction and percutaneous Kirschner wire internal fixation, including 10 males and 3 females. The age ranged from 3 to 14 years old.

Survival prediction modelling in patients with acute ST-segment elevation myocardial infarction with LASSO regression and explainable machine learning.

Background: Acute ST-segment elevation myocardial infarction (STEMI) is a cardiovascular emergency that is associated with a high risk of death. In this study, we developed explainable machine learning models to predict the overall survival (OS) of STEMI patients to help improve prognosis and increase survival.

Methods: After applying the inclusion and exclusion criteria, we selected 893 patients who underwent emergency coronary angiography and percutaneous coronary intervention (PCI) for STEMI at the First Affiliated Hospital of Kunming Medical University.

Investigation of early-stage cardiovascular-kidney-metabolic syndrome on retinal structure and function evaluated by optical coherence tomography angiography.

Background: The retina serves as a non-invasive window to visualize systemic health, with optical coherence tomography angiography (OCTA) enabling simultaneous assessment of retinal structural thickness and vascular density. Suboptimal cardiovascular-kidney-metabolic (CKM) health status, defined by the early stage of CKM syndrome, may impact retinal neurovascular integrity, yet comprehensive OCTA-based evaluations remain limited and controversial. This study aimed to investigate retinal structural and vascular alterations in the early-stage CKM using OCTA and explore its potential as a biomarker tool.

Polymer/Graphene Composite with Multiple Active Sites Enables Membrane-Free Decoupled Hydrogen Production in Acidic Electrolyte.

Decoupled water electrolysis using solid-state redox mediators (SRMs) enables spatial and temporal separation of hydrogen and oxygen production without relying on membranes. Here, a nitrogen-containing heterocyclic quinone polymer (PYTQ) was integrated with reduced graphene oxide (RGO) via vacuum-assisted filtration to synthesize the composite material (PYTQ-RGO). Benefiting from the multiple active sites for PYTQ and the strong π-π interactions between PYTQ and RGO, the composite exhibits high specific capacity and excellent stability.

is involved in yield-related traits and cell proliferation of maize.

Heterotrimeric G-proteins are multifunctional modulators that participate in a wide range of growth and developmental processes in eukaryotic species, including yeast, plants, and animals. In this study, we characterized a maize mutant, , that showed a compact architecture and reproductive-organ-related phenotypic variation. Heredity analysis indicated that the mutant phenotypes resulted from monogenic inheritance.

PHRF-RTDETR: a lightweight weed detection method for upland rice based on RT-DETR.

Introduction: Weed poses a greater threat to rice yield and quality in upland environments compared to paddy fields. Effective weed detection is a critical prerequisite for intelligent weed control technologies. However, the current weed detection methods for upland rice often struggle to achieve a balance between accuracy and lightweight design, significantly hindering the practical application and widespread adoption of intelligent weeding technologies in real-world agricultural scenarios.

Built-in Electric Field Boosted Tandem Catalysis for Rapid Electrochemical Nitrate Reduction to Nitrogen.

Nitrate pollution in water bodies urgently necessitates sustainable electrocatalytic nitrate reduction (NORR) technologies, yet achieving high-efficiency catalysis for NORR with optimized interfacial charge distribution on electrocatalyst remains challenging. Herein, we report a built-in electric field (BIEF) construction strategy using mesoporous carbon-supported Co/CoO heterojunction catalyst (Co/CoO-meso-C), which delivered exceptional NORR performance with 90.77% nitrate removal, 99% N selectivity (-1.

Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study.

Objective: The objective is to examine the epidemiology and clinical features of human cases infected with H5N6 avian influenza in Sichuan Province from 2014 to 2024, and to offer guidance for the prevention and management of human infections with H5N6 avian influenza.

Methods: Epidemiological survey reports of H5N6 avian influenza cases in Sichuan Province from 2014 to 2024 were compiled, and the epidemiological context and characteristics of 16 human cases infected with H5N6 avian influenza in the province were summarized and analyzed using descriptive epidemiological methods.

Results: From 2014, when the initial human case ofH5N6 infection was documented in Sichuan Province, to 2024, there have been 16 human cases of H5N6 avian influenza in the region, resulting in 12 fatalities and a case fatality rate of 75%.

Gram-Scale Ammonia Synthesis via Electrochemical Nitrate Reduction Using Enzyme-Inspired Dual-Atomic Cu Catalyst.

The potential application prospects of green electricity-driven electrocatalytic nitrate reduction (NO₃RR) technology for the production of valuable ammonia have garnered widespread attention. However, designing electrocatalysts with remarkable activity and stability for the NO₃RR to realize gram-level ammonia production remains a significant hurdle in terms of practical application. In nature, the synergistic effect of the dual-site copper of nitrite reductase promotes the substrate adsorption and protonation, achieving efficient conversion of nitrite.

Allergic Skin Inflammation Drives IL-4-Dependent Differentiation of Dermal CD11b-low Dendritic Cells.

IL-13 produced by type 2 innate lymphoid cells is crucial for the steady-state differentiation of dermal CD11b-low type 2 dendritic cells (DC2s), a murine KLF4-dependent DC2 population that is found only in the skin and drives enhanced T helper 2 differentiation. In this study, we examined how CD11b-low DC2s respond to skin inflammation, particularly in the absence of IL-13. We employed a model of MC903-induced atopic dermatitis in which CD11b-low DC2s migrate from skin to the draining lymph node in a TSLP receptor-dependent manner, temporarily depleting the skin CD11b-low population.

[Retracted] Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3‑kinase/protein kinase B signaling pathway in mice during cardiac surgery.

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that the flow cytometric assay data shown in Fig. 16 on p. 6053 had already appeared in an article written by different authors at a different research institute that was published previously in the journal .

Unraveling the Molecular Pathways of Protein Fibrillation under Thermal Acid Hydrolysis.

Artificial amyloid fibrils formed by globular proteins under thermal acid hydrolysis have drawn extensive attention due to their exceptional mechanical properties and ability to form functional materials. However, the mechanisms underlying their formation, particularly the initiation of fibrillation under heat-induced acid hydrolysis, are not yet fully understood. By developing a general approach that integrates experiment and theory, the molecular pathways by which β-lactoglobulin (β-lg) monomers convert into artificial fibrils under heat-induced aggregation and acid hydrolysis at concentrations of 0.

Improvement of antioxidant capacity and gut microbiota balance in adult zebrafish (Danio rerio) by addition of fermented distillers' dried grains with solubles (DDGS).

The continuous high price of fishmeal has prompted the aquaculture industry to seek alternative protein sources. Distillers' dried grains with solubles (DDGS) possess significant utilization value as a plant-based protein, yet its substitution ratio is limited due to the anti-nutritional factors. This study aimed to assess the potential of compound bacteria-fermented DDGS as a protein source for aquatic feed.

Recent progress on biosensors for detection of circulating miRNA biomarkers.

Circulating miRNAs are a class of non-coding endogenous RNAs found in body fluids which typically consist of 19-24 nucleotides in length. The abnormal expression of miRNAs has been demonstrated to be associated with severe human diseases. Aiming to provide valuable insights for the further development of reliable miRNA detectors for disease early diagnosis and treatment, this work systematically summarizes the latest advancements in signal amplification strategies for miRNA analysis, based on nanomaterials, nucleic acids, enzymes, and CRISPR/Cas system.

Targeted inhibition of JMJD2C/MALAT1 axis compensates for the deficiency of metformin in reversing ovarian cancer platinum resistance.

Aims: We explored JMJD2C's role in platinum resistance in ovarian cancer and its modulation by metformin to propose strategies for overcoming treatment limitations.

Materials And Methods: JMJD2C and MALAT1 expression was assessed via RT-qPCR, western blotting, and immunohistochemical assays using OC cell lines, tissue from OC patients, and xenograft treatment with or without metformin. CCK-8 assays, flow cytometry, inductively coupled plasma mass spectrometry, luciferase reporter assays, and ChIP assays were employed to evaluate the impact of JMJD2C/MALAT1 on PR and the effects of metformin on JMJD2C.

Enhancing the Photovoltaic Performance of Directional-Growing Two-Dimensional Perovskites by Out-of-Plane Polarization.

Two-dimensional (2D) perovskites have great application potential in the photovoltaic field, but the carriers can only be transmitted in-plane due to the limitation of the quantum well structure. It is usually necessary to induce a vertical orientation in photovoltaic devices to overcome this limitation. Here we find that the carrier limitation of 2D perovskites can be overcome by out-of-plane polarization.

Integrated transcriptome and metabolome analysis reveals the impacts of prolonged light exposure on starch and protein content in maize kernels.

Background: The light environment significantly influences crop growth, development, quality, and yield, particularly in controlled-environment agriculture. Recent advances in artificial lighting technology have allowed growers to precisely control the light environment in terms of duration, spectrum, and intensity. Starch and protein are the most significant nutritional constituents of maize kernels.

Constructing Asymmetric SiO/C Janus Structures with Diverse Carbon Density Frameworks Enables Electrochemical Stability.

The main challenges limiting the practical application of silicon-based anode materials are volume fluctuations during cycling and poor intrinsic conductivity. One of the most effective strategies to address these limitations is the incorporation of carbon materials into silicon composites. However, few studies have investigated the impact of diverse carbon density frameworks on electrochemical performance, primarily due to the challenges associated with structural construction.

Uranium immobilization via sulfur-modified Fe nanoparticles: U(VI) trapping kinetics and long-term stability evaluation.

The modification of nanoscale zero-valent iron (nZVI) by loading or incorporating sulfur into the iron crystal lattice can augment their efficacy in the removal of hydrophobic contaminants from wastewater. Nevertheless, the reactivity of sulfur-embedded nZVI (SnZVI) in immobilizing hydrophilic uranyl ions and the long-term stability of the sequestered uranium has received little attention. This study employed NaSO to modify the nZVI with different S/Fe molar ratios (0.

Valorizing Nitrate in Electrochemical Nitrogen Cycling: Copper-Based Catalysts from Reduction to C-N Coupling.

Electrochemical nitrate reduction (NORR) offers a sustainable approach to mitigating nitrogen pollution while enabling the resourceful conversion of nitrate (NO ) into ammonia (NH), nitrogen gas (N), and value-added chemicals such as urea. Copper (Cu)-based catalysts, with their versatile catalytic properties and cost-effectiveness, have emerged as pivotal materials in advancing NORR. This review systematically summarizes recent progress in Cu-based catalysts for NORR, focusing on their catalytic mechanisms, tuning strategies, and applications across diverse product pathways.

[Corrigendum] Effects of nicorandil on p120 expression in the spinal cord and dorsal root ganglion of rats with chronic postsurgical pain.

Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that certain of the figures associated with four separate papers published by the same research group, and featuring some of the same authors, appeared to share immunofluorescence and graphical data. Upon analyzing the data independently in the Editorial Office, as far as the paper above was concerned, the diagram depicting the establishment of the skin/muscle incision and retraction (SMIR) model in rats, as featured in Fig. 1A on p.

Solid-state fermentation through synthetic microbiome: An effective strategy for converting Chinese distillers' grains into functional protein feed.

Chinese distillers' grains (CDGs), a byproduct of liquor production, have low protein, high fiber, and elevated alcohol/lactic acid levels, limiting their use as animal feed. This study utilised a synthetic microbiome composed of Candida utilis (protein enhancement), Trichoderma viride (fiber reduction), Bacillus subtilis (detoxification), and Lactobacillus casei (functional enhancement) for solid-state fermentation. The results showed that crude protein content increased to 23.

Machine Learning-Assisted Prediction and Exploration of the Homogeneous Oxidation of Mercury in Coal Combustion Flue Gas.

Mercury emission from coal combustion flue gas is a significant environmental concern due to its detrimental effects on ecosystems and human health. Elemental mercury (Hg) is the dominant species in flue gas and is hard to immobilize. Therefore, it is necessary to comprehend the reaction mechanisms of Hg oxidation, namely, Hg to oxidized mercury (Hg), for mercury immobilization.

Effect of tandem autologous stem cell transplantation on survival in pediatric patients with high-risk solid tumors in South China.

Background: Despite advances in treatment, the prognosis for patients with high-risk pediatric solid tumors remains dismal. Tandem autologous stem cell transplantation (ASCT) offers promise for improving outcomes in these patients. This study aimed to examine the efficacy and prognostic factors of tandem ASCT in pediatric patients with high-risk solid tumors.

Synthesis of Selenized Metal-Organic Framework Hollow Cage under Ambient Condition for Clean Energy Applications.

The synthesis of structured metal organic framework (MOF)-derived selenide composites is a vibrantly emerging research area serving clean energy purposes. However, there is no way to convert MOFs into structured selenide composites under ambient conditions for unknown reasons. This work gave mechanistic insights into how the redox properties and release rate of selenium precursors influenced the structural inheritance behavior of MOFs during the selenization process, explaining why maintaining the morphology of MOFs during a room-temperature aqueous selenization process is a tricky task.