Imageological/Structural Study regarding the Improved Pharmacokinetics by Ga-Labeled PEGylated PSMA Multimer in Prostate Cancer.

PMSA (prostate-specific membrane antigen) is currently the most significant target for diagnosing and treating PCa (prostate cancer). Herein, we reported a series Ga/Lu-labeled multimer PSMA tracer conjugating with PEG chain, including [Ga]Ga-DOTA-(1P-PEG), [Ga]Ga-DOTA-(2P-PEG), [Ga]Ga-DOTA-(2P-PEG), and [Ga]Ga/[Lu]Lu-DOTA-(2P-PEG), which showed an advantage of a multivalent effect and PEGylation to achieve higher tumor accumulation and faster kidney clearance. To figure out how structural optimizations based on a PSMA multimer and PEGylation influence the probe's tumor-targeting ability, biodistribution, and metabolism, we examined PSMA molecular probes' affinities to PC-3 PIP (PSMA-highly-expressed PC-3 cell line), and conducted pharmacokinetics analysis, biodistribution detection, small animal PET/CT, and SPECT/CT imaging.

A Physical Model to Describe the Motion Behavior of BNNSs under Nanosecond Pulses.

This paper presents a physical model that provides a comprehensive understanding of the motion behavior of boron nitride nanosheets (BNNSs) immersed in ultrapure deionized water and subjected to a series of nanosecond pulses. In a study conducted by Y. Mi et al.

Universal Renaissance Strategy of Metal Fluoride in Secondary Ion Batteries Enabled by Liquid Metal Gallium.

All-solid-state alkali ion batteries represent a future trend in battery technology, as well as provide an opportunity for low-cost metal fluoride electrode materials, if certain intrinsic problems can be resolved. In this work, a liquid metal activation strategy is proposed in which liquid Ga elements are generated in situ and doped into the LiF crystal structure by introducing a small amount of GaF . Benefiting from these two Ga states of existence, in which the liquid metal Ga can continuously maintain conformable ion/electron-transport networks, while doped Ga in the LiF crystal structure catalyzes LiF splitting, the lithium-ion storage capacity of MnF significantly increases by 87%.

Deforming lanthanum trihydride for superionic conduction.

With strong reducibility and high redox potential, the hydride ion (H) is a reactive hydrogen species and an energy carrier. Materials that conduct pure H at ambient conditions will be enablers of advanced clean energy storage and electrochemical conversion technologies. However, rare earth trihydrides, known for fast H migration, also exhibit detrimental electronic conductivity.

Structural Engineering Enabled Bimetallic (Ti Nb ) AlC Solid Solution Structure for Efficient Electromagnetic Wave Absorption in Gigahertz.

Microstructures play a critical role to influence the polarization behavior of dielectric materials, which determines the electromagnetic response ability in gigahertz. However, the relationship between them, especially in the solid-solution structures is still absent. Herein, a series of (Ti Nb ) AlC MAX phase solid solutions with nano-laminated structures have been employed to illuminate the aforementioned problem.

Monomer Symmetry-Regulated Defect Engineering: In Situ Preparation of Functionalized Covalent Organic Frameworks for Highly Efficient Capture and Separation of Carbon Dioxide.

Developing crystalline porous materials with highly efficient CO selective adsorption capacity is one of the key challenges to carbon capture and storage (CCS). In current studies, much more attention has been paid to the crystalline and porous properties of crystalline porous materials for CCS, while the defects, which are unavoidable and ubiquitous, are relatively neglected. Herein, for the first time, we propose a monomer-symmetry regulation strategy for directional defect release to achieve in situ functionalization of COFs while exposing uniformly distributed defect-aldehyde groups as functionalization sites for selective CO capture.

Dual Charge-Transfer Channels Harmonize Carrier Separation for Efficient U(VI) Photoreduction.

The low efficient transfer of photogenerated electrons to an active catalytic site is a pivotal problem for the photoreduction of highly soluble hexavalent uranium [U(VI)] to low soluble tetravalent uranium [U(IV)]. Herein, we successfully synthesized a TiO/1T-MoS/reduced graphene oxide heterojunction (TTMR) with dual charge-transfer channels by exploiting the difference in Fermi levels between the heterojunction interfaces, which induced multilevel separation of photogenerated carriers. Theoretical and experimental results demonstrate that the presence of the electron buffer layer promoted the efficient migration of photogenerated electrons between the dual charge-transfer channels, which achieved effective separation of photogenerated carriers in physical/spatial dimensions and significantly extended the lifetime of photogenerated electrons.

High Quantum Efficiency Rare-Earth-Doped GdOS:Tb, F Scintillators for Cold Neutron Imaging.

High-resolution neutron radiography provides novel and stirring opportunities to investigate the structures of light elements encased by heavy elements. For this study, a series of GdOS:Tb, F particles were prepared using a high-temperature solid phase method and then used as a scintillation screen. Upon reaching 293 nm excitation, a bright green emission originated from the Tb luminescence center.

Complexation of a Nitrilotriacetate-Derived Triamide Ligand with Trivalent Lanthanides: A Thermodynamic and Crystallographic Study.

Non-heterocyclic N-donor nitrilotriacetate-derived triamide ligands are one of the most promising extractants for the selective extraction separation of trivalent actinides over lanthanides, but the thermodynamics and mechanism of the complexation of this kind of ligand with actinides and lanthanides are still not clear. In this work, the complexation behaviors of ,,',',″,″-hexaethylnitrilotriacetamide (NTAamide(Et)) with four representative trivalent lanthanides (La, Nd, Eu, and Lu) were systematically investigated by using H nuclear magnetic resonance (H NMR), ultraviolet-visible (UV-vis) and fluorescence spectrophotometry, microcalorimetry, and single-crystal X-ray diffractometry. H NMR spectroscopic titration of La and Lu indicates that two species of 1:2 and 1:1 metal-ligand complexes were formed in NO and ClO media.

Nano-Voids in Ultrafine Explosive Particles: Characterization and Effects on Thermal Stability.

Ultrafine explosives show high safety and reliable initiation and have been widely used in aerospace, military, and industrial systems. The outstanding performance of ultrafine explosives is largely given by the unique void defects according to the simulation results. However, the structures and effects of internal nano-voids in ultrafine explosive particles have been rarely investigated experimentally.

Linear Fitting of Time-Varying Signals in Static Noble Gas Mass Spectrometry Should Be Avoided.

This Perspective highlights a malpractice during data processing in static noble gas mass spectrometry, viz. retrodicting the noble gas signals at "time zero" based on the linear fitting results of the time-varying analytical responses. Linear fitting is the most commonly used by noble gas analysts mainly on the consideration of high coefficient of determination (R), while it poses risks of inaccurate estimation of required information.

Microstructure and Mechanical Properties of the 6 wt% Mn-Doped Martensitic Steel Strengthened by Cu/NiAl Nanoparticles.

The microstructure and mechanical properties of 6 wt.% Mn-doped martensitic steel have been investigated through a combination of electron backscatter diffraction (EBSD), transmission electron microscopy (TEM), and small-angle neutron scattering (SANS). The 6 wt.

Research on the relationship between the scattering contribution and physical factors of the reference radiation regulated by ISO 4037-1.

In the latest version of ISO 4037-1:2019 standard, the minimum dimension of a gamma radiation reference field was not clearly specified, which makes the construction of a minitype gamma reference radiation field lack of scientific basis. This paper carried out the research on the relationship between the scattering contribution and physical factors of the reference radiation regulated by ISO 4037-1. LS-SVM was applied to construct the relational model between physical factors and scattering contribution based on the data simulated by Monte Carlo method.

Boosting the lithium-ion storage performance of perovskite SrVO via Sr cation and O anion deficient engineering.

Perovskite SrVO has been investigated as a promising lithium storage anode where the V cation plays the role of the redox center, combining excellent cycle stability and safe operating potential versus Li metal plating, with limited capacity. Here, we demonstrate the possibility to boost the lithium storage properties, by reducing the non-redox active Sr cation content and fine-tuning the O anion vacancies while maintaining a non-stoichiometric SrVO perovskite structure. Theoretical investigations suggest that Sr vacancy can work as favorable Li storage sites and preferential transport channels for guest Li ions, contributing to the increased specific capacity and rate performance.

A chiral BINOL-based supramolecular gel enabling sensitive enantioselective and chemoselective collapse toward histidine.

A chiral small molecule gelator ()-HL based on 1,1'-bi-2,2'-naphthol (BINOL)-phosphoric acid was designed and prepared, which spontaneously forms a stable water-induced gel. The gelation mechanism was revealed by single crystal X-ray diffraction analysis and a number of spectroscopic methods. Addition of Cu improved the gelation ability, and the resultant metal organic gel realized visual enantioselective and chemoselective recognition toward L-histidine from enantiomers of 19 amino acids gel collapse.

Enhanced Electron-Hole Separation in Phosphorus-Coordinated Co Atom on g-CN toward Photocatalytic Overall Water Splitting.

Revealing the decoration mode of g-CN and understanding the physical mechanism of overall water splitting is important for the further improvement of the photocatalytic activity of g-CN-based materials. With core level shift and molecular dynamics simulations based on first-principles calculations, Co(PH) anchored on the triazine of g-CN is determined as a stable single-atom catalyst with high efficiency for photocatalytic overall water splitting. The separated spin-polarized charge density distribution of valence-band maximum and conduction-band minimum states is beneficial for the long lifetime of photoexcited electrons and holes.

Retraction: A carboxymethyl cellulose modified magnetic bentonite composite for efficient enrichment of radionuclides.

[This retracts the article DOI: 10.1039/C6RA10990J.].

Amorphous Ni-Co binary hydroxide with super-long cycle life and ultrahigh rate capability as asymmetric supercapacitors.

Ni-Co binary hydroxide (NiCo(OH)) with nanostructure is prepared by one-step electrochemical deposition process with de-ionized water as electrolyte. The molar ratio of Ni/Co for NiCo(OH)can be accurately controlled via changing the composition of the alloy target. A series of typical hydroxides are synthesized with Ni/Co molar ratios of 1:2, 1:3, 1:4, 1:6, 6:1, 4:1, 3:1, 2:1 and 1:1.

Revealing the Defect-Dominated Electron Scattering in MgSb-Based Thermoelectric Materials.

The thermoelectric parameters are essentially governed by electron and phonon transport. Since the carrier scattering mechanism plays a decisive role in electron transport, it is of great significance for the electrical properties of thermoelectric materials. As a typical example, the defect-dominated carrier scattering mechanism can significantly impact the room-temperature electron mobility of n-type MgSb-based materials.

Dense dislocations enable high-performance PbSe thermoelectric at low-medium temperatures.

PbSe-based thermoelectric materials exhibit promising ZT values at medium temperature, but its near-room-temperature thermoelectric properties are overlooked, thus restricting its average ZT (ZT) value at low-medium temperatures. Here, a high ZT of 0.90 at low temperature (300-573 K) is reported in n-type PbSe-based thermoelectric material (PbSeTeS-0.

Insights into the spontaneous multi-scale supramolecular assembly in an ionic liquid-based extraction system.

Herein, we report a four-step mechanism for the spontaneous multi-scale supramolecular assembly (MSSA) process in a two-phase system concerning an ionic liquid (IL). The complex ions, elementary building blocks (EBBs), [EBB] clusters and macroscopic assembly (MA) sphere are formed step by step. The porous large-sized [EBB] clusters in the glassy state can hardly stay in the IL phase and they transfer to the IL-water interface due to both electroneutrality and amphiphilicity.

Effect of Ta Interlayers on Texture and Magnetic Properties of FeSi Films with Micrometer Thickness.

Magnetized soft ferromagnetic films with micrometer thickness were studied. A FeSi film, with a total thickness of 2000 nm, separated by 10 nm-thick Ta interlayers, was fabricated using the direct-current magnetron sputtering technique. The thickness of each FeSi layer between adjacent Ta layers was 100 nm.

Near-Infrared Photothermally Enhanced Photo-Oxygenation for Inhibition of Amyloid-β Aggregation Based on RVG-Conjugated Porphyrinic Metal-Organic Framework and Indocyanine Green Nanoplatform.

Amyloid aggregation is associated with many neurodegenerative diseases such as Alzheimer's disease (AD). The current technologies using phototherapy for amyloid inhibition are usually photodynamic approaches based on evidence that reactive oxygen species can inhibit Aβ aggregation. Herein, we report a novel combinational photothermally assisted photo-oxygenation treatment based on a nano-platform of the brain-targeting peptide RVG conjugated with the 2D porphyrinic PCN-222 metal-organic framework and indocyanine green (PCN-222@ICG@RVG) with enhanced photo-inhibition in Alzheimer's Aβ aggregation.

Equation of state of Iridium: from insight of ensemble theory.

The equations of state (EOS) of Iridium are, for the first time, obtained by solving the high-dimension integral of partition function based on a recently developed approach of ultrahigh efficiency and precision without any artificial parameter, and the deviation of 0.25% and 1.52% from the experiments was achieved respectively for the isobaric EOS in a temperature range of 300 K-2500 K and the isothermal EOS at 300 K up to 300 GPa.