General event-triggered dynamic output feedback control for complex networks subject to cyber attacks.

This article concentrates on the issue of event-triggered dynamic output feedback control for Markovian jump complex dynamical networks (MJCNDs) subject to multiple cyberattacks. To alleviate the communication pressure, a new adaptive event-triggered mechanism (AETM) is proposed. This AETM incorporates a dynamically adjustable parameter and mode-dependent properties to enhance flexibility.

The impact of maternal dietary supplementation with lysozyme oligomer on farrowing performance and placental inflammation in sows.

This study evaluated the effects of maternal lysozyme oligomer (LYZ) supplementation on sow reproductive performance and piglet growth performance. Multiparous sows were randomly allocated to two groups: control and 0.1 % dietary LYZ.

Research on Material Basis and Quality Control of Folium, a Traditional Medicinal and Edible Material.

Folium (AAF) is a traditional medicinal and edible material. However, the pharmacologically active compounds and quality control of AAF have not been fully investigated. To solve these problems, we developed a novel method based on HPLC-Q-Exactive Orbitrap-HRMS for rapid identification of chemical compounds in AAF.

MYC and p53 Alterations Cooperate through VEGF Signaling to Repress Cytotoxic T Cell and Immunotherapy Responses in Prostate Cancer.

Patients with castration-resistant prostate cancer (CRPC) are generally unresponsive to tumor targeted treatments and immunotherapies. Genetic alterations acquired during the evolution of CRPC may impact anti-tumor immunity and immunotherapy responses, which could inform personalized therapeutic strategies. Using our innovative electroporation-based mouse models, we generated distinct genetic subtypes of CRPC found in patients and uncovered unique immune microenvironments.

Controllable Synthesis of an Upconversion Metal-Organic Framework Core-Shell Hybrid for Highly Sensitive Fluorescence Detection of Dufulin in Crops and Fruits.

Developing a sensitive analysis of dufulin with high anti-interference performance remains challenging. Herein, a metal-organic framework (MOF)-encapsulated upconversion nanoparticle (UC) core-shell hybrid sensor (UC@CuMOF) was designed for the sensitive detection of dufulin. With the encapsulation of the CuMOF shell, the luminescence of UC under a 980 nm laser was strongly quenched by the shell through the photoinduced electron transfer effect.

Iron-doped carbon dots with multi-enzyme activities for rapid determination of phenolic compounds.

Multi-enzymic nanozymes have attracted growing attention due to their distinct advantages over single enzyme-like nanozymes, particularly their synergistic effects and cascaded reactions. Herein, iron-doped carbon dots (FeCDs) were prepared by a one-step calcination method using hemin chloride, histidine, and potassium citrate as precursors. The resultant FeCDs exhibit a monodispersed spherical structure with an average particle size of 1.

0618A Volatiles Inhibit and Enhance Soil Health in the Biocontrol of Peanut Southern Blight.

Peanut southern blight, caused by , is a severe soil-borne disease. Given the adverse effects associated with chemical fungicides, this study investigated the biocontrol potential of volatile organic compounds (VOCs) from 0618A. VOCs produced by 0618A at 1 × 10 CFU/mL almost completely inhibited mycelial growth and sclerotia germination.

BST-2 Promotes N Protein Degradation and Inhibits Viral Replication Through the MARCHF8/NDP52 Autophagy Pathway.

Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a recently discovered enteric coronavirus that has caused considerable economic losses in the pig industry. SADS-CoV was first reported in 2017 in Guangdong Province, China, and subsequently in Fujian, Guangxi, Henan and Jiangxi Provinces. Bone marrow stromal cell antigen 2 (BST-2), also known as tetherin, acts as an antiviral protein to limit the release of a wide range of enveloped viruses.

What do we know about midwife-woman interactions during vaginal childbirth: a scoping review and thematic analysis.

Background: Against the backdrop of changes in the medical model, a clearer awareness among women of their rights, and a deeper emphasis on the "woman-centred" approach, it has become increasingly important to focus on the current state and quality of intrapartum interactions. While midwife-woman interactions during vaginal childbirth are recognized as central to shaping maternal health outcomes and birthing experiences, existing studies offer fragmented insights, with a limited synthesis of how these dynamics influence intrapartum care and support, maternal autonomy in decision-making, and the midwife-woman relationship.

Objectives: To synthesize the existing literature addressing midwife-woman interactions during childbirth and to identify any research gaps.

Chromatographic analysis and monitoring of fault gases in substation using ZIF-8 coated capillary column.

This study developed a ZIF-8-coated capillary gas chromatography column for the efficient separation of critical fault gases in electrical substations. By optimizing the carrier gas flow rate (3.5 mL/min) and column temperature (40°C), baseline separation of all components was achieved within 12 min, with resolution values of 0.

Highly Discriminative Detection of Nitrophenol Isomers by Covalent Organic Framework Membrane-Modified Electrochemical Sensors.

Nitrophenol isomers (NPs), namely, -, -, and -nitrophenol (-NP, -NP, and -NP) are an important class of organic compounds widely employed in industrial fields. Due to their high chemical stability, resistance to natural degradation, and toxicity, NPs pose significant risks to both the environment and human health. Their discriminative detection is of paramount significance; however, it is highly challenging because of the structural and physicochemical similarities of NPs.

Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer miR-485-5p/STAT3.

Background: Gastric cancer (GC) is a type of cancer which causes high cancer-related mortality. Surgical operation and systematic chemical therapies are primary choices for the treatment of GC patients with advanced stages, however, the 5-year overall survival is only around 30%.

Aim: To investigate the role of mesenchymal stem cell (MSC)-derived long non-coding RNAs (lncRNA) NKILA in fatty acid oxidation and chemoresistance in GC cells, mediated through the miR-485-5p/STAT3 pathway.

Neoadjuvant chemoimmunotherapy versus neoadjuvant chemoradiotherapy in patients with borderline resectable esophageal squamous cell carcinoma.

Background: The optimal treatment strategy for patients with borderline resectable (cT3br) esophageal squamous cell carcinoma (ESCC) remains unclear. Thus, the aim of this study was to compare the perioperative outcomes and prognoses between neoadjuvant chemotherapy combined with immunotherapy (NACI) and neoadjuvant chemoradiotherapy (NCRT) in cT3br ESCC patients.

Methods: In this retrospective cohort study, patients with cT3br ESCC who received either NACI or NCRT followed by surgery between January 2016 and December 2022 were identified.

Canagliflozin inhibits hepatic stellate cells activation and proliferation by inhibiting PP2A-mediated β-catenin dephosphorylation to attenuate hepatic fibrosis.

Hepatic fibrosis (HF) is a leading cause of death worldwide, yet there is currently no safe and effective treatment available. Canagliflozin, a novel glucose-lowering drug, has been shown to improve non-alcoholic steatohepatitis (NASH). However, its therapeutic effects on HF and the underlying molecular mechanisms remain unclear.

Ultrasound and genetic findings in a case series of fetuses presenting vertebral defects.

Purpose: This study aimed to summarize the ultrasound and genetic features in a case series of fetuses presenting vertebral defects, to provide useful information for prenatal counseling and prognostic evaluation.

Methods: Fetuses with vertebral anomalies by a second or third trimester ultrasound screening between January 2020 and April 2024 at a single center were included in the study. Chromosome microarray analysis (CMA) as a first-line diagnostic test was performed.

Disulfiram Protects Against Multiorgan Injuries and Cell Pyroptosis via Inhibiting GSDMD in Severe Acute Pancreatitis Mice.

Severe acute pancreatitis (SAP) is distinguished by an uncontrolled systemic pro-inflammatory response caused by the activation of trypsin within the pancreatic tissue, leading to the occurrence of multiple organ failure (MOF). Gasdermin D (GSDMD)-induced pyroptosis represents a form of programmed cell death characterised by robust inflammatory responses. This indicates that directing efforts towards pyroptosis could potentially offer a remedy for SAP and its related MOF.

Fermentation kinetics, physicochemical properties, and antioxidant activity of Fuji apple cider fermented with different yeast strains.

This study compared the fermentation kinetics, physicochemical properties, antioxidant activity, and sensory profiles of Fuji apple cider fermented with five commercial yeast strains: Fermol blanc, RC212, Zymaflora F15, La Raffinee, and Koya FC9. Significant strain-dependent differences were observed among these strains in multiple aspects of fermentation performance. La Raffinee exhibited the highest yeast growth peak (7.

Effect of low-energy stirring temperature on the formation of oil-in-water emulsions stabilized by gelatin-arginine complexes.

The impact of low-energy stirring temperatures (30 °C, 50 °C, 70 °C, 90 °C) on the stability of gelatin emulsions was investigated when stirring with a magnetic stirrer at 1600 rpm for 3.5 h at an arginine (Arg) concentration of 1.2 % (w/v).

The Duration of Prophylactic Antibiotic Use for Esophageal Cancer Patients with Postoperative Infection and Nutritional Status.

Objective: To verify the hypothesis that "the prophylaxis use time of antibiotics after esophageal cancer (EC) surgery ≤24 hours is associated with a lower postoperative infection rate and improvement of nutritional indicators", a retrospective cohort analysis was conducted to compare the infection incidence and differences in serum nutritional indicators among patients with different medication durations (< 24 hours, 24-48 hours, > 48 hours), and to identify independent risk factors for postoperative infection.

Methods: A retrospective analysis was conducted on the data of 566 patients who underwent EC surgery in Affiliated Hospital of North Sichuan Medical College from January 2020 to October 2022. Patients were divided into three groups based on the duration of postoperative antibiotic prophylaxis: Group A (<24 hours), Group B (24-48 hours), and Group C (>48 hours).

Association between 24hour movement behaviors and psychological wellbeing in overweight and obese children.

Objectives: The 24-hour movement behaviors, comprising physical activity, sedentary behavior, and sleep, are crucial factors affecting children's mental health. This study aims to explore the longitudinal association between 24-hour movement behaviors and psychological well-being in overweight and obese children, providing empirical evidence for mental health promotion in this population.

Methods: A total of 445 overweight and obese children were recruited via stratified cluster random sampling from a provincial capital city in China and followed up for one year.

Prenatal Characterization of Houge-Janssens Syndrome Type 2: A Case Report and Systematic Review of Fetal Phenotypes Associated With PPP2R1A Mutations.

Background: Houge-Janssens syndrome type 2 (HJS2, OMIM 616362) is a rare neurodevelopmental disorder caused by pathogenic variants in PPP2R1A, typically characterized postnatally by hypotonia, developmental delay, intellectual disability, and distinctive craniofacial features.

Methods: We describe a 28-year-old pregnant woman referred for increased nuchal translucency (4.4 mm) and high risk on first trimester screening.

Fully printed multimodal sensing system for continuous health monitoring during exercise.

Continuous monitoring of physicochemical information during exercise using wearable and implantable systems is critical for disease management and health monitoring. However, it remains challenging due to limited multimodal system integration, poor detection precision, and rigidity of the equipment. Herein, we present a fully printed multimodal sensing system (MSS) that integrates an implantable glucose/lactate biosensor, wearable electrocardiogram (ECG) and temperature sensors with the reusable electronics.

Resistance risk and mechanism of prochloraz in Fusarium solani.

Peanut root rot (PRR) is caused by Fusarium solani, which severely affects the yield and quality of peanuts. Prochloraz is a triazole-based demethylation inhibitor (DMIs) fungicide with antifungal activity against Fusarium spp. However, the resistance risk and resistance mechanisms of F.

Long-Term Outcomes of Endoscopic Ultrasound-Guided Coloenterostomy With a Lumen-Apposing Metal Stent for Malignant Small Bowel Obstruction.

Background And Aims: Endoscopic ultrasound-guided coloenterostomy (EUS-CE) using lumen-apposing metal stents (LAMS) has emerged as a potential alternative for the palliative treatment of malignant small bowel obstruction (MSBO). However, the long-term outcomes of EUS-CE remain unclear. This study aimed to assess the efficacy and safety of EUS-CE, focusing on long-term outcomes.

Foodborne Botulism Caused by Subtype A5(b3) by Self-Packaged Vacuum Spicy Rabbit Heads.

Botulism is a severe muscle paralysis disease mediated by the botulinum toxin. Here, we reported a foodborne botulism case caused by subtype A5(b3) from self-packaged vacuum spicy rabbit heads. Treatment for this case was delayed due to misdiagnosis and insufficient diagnostic capacity in three hospitals, which resulted in progressive clinical deterioration, and eventually, the patient was transferred to Shandong Public Health Clinical Center for specialized therapy.