3,616,184 results match your criteria: "China; Shandong Engineering Research Center for Transdermal Drug Delivery Syst[Affiliation]"

Successful biological control requires accurate knowledge of the host preference of the released parasitoid. Telenomus remus Nixon (1973) is an effective parasitoid of Spodoptera frugiperda (J.E.

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Correlated spiking has been widely found in large population of neurons and been linked to neural coding. Transcranial alternating current stimulation (tACS) is a promising non-invasive brain stimulation technique that can modulate the spiking activity of neurons. Despite its growing application, the tACS effects on the temporal correlation between spike trains are still not fully understood.

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This study aims to systematically assess the therapeutic effectiveness of TiRobot-assisted percutaneous kyphoplasty or vertebroplasty in managing osteoporotic thoracolumbar compression fractures. Previous studies have suggested that TiRobot-assisted techniques outperform conventional manual procedures in treating this condition, but relevant conclusions remain controversial. A thorough literature retrieval was carried out across 4 major databases: PubMed, Embase, the Cochrane Library, and Web of Science.

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Lead (Pb) contamination, a kind of heavy metal pollution, severely impacts organism growth and reproduction. Although vitellogenin (Vg) has been studied in many species, its characteristics in the pest Aleuroglyphus ovatus (Troupeau) (Acari: Acaridae) remain unknown. In this study, the full-length Vg gene of A.

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Urban-impacted river pollutant sources: WQI ranking and PMF analysis.

Environ Monit Assess

September 2025

School of Materials Engineering, Changzhou Vocational Institute of Industry Technology, Changzhou, 213000, People's Republic of China.

A multi-indicator framework was developed to resolve multi-source pollution in highly urbanized rivers, demonstrated in the Qinhuai River Basin, Nanjing, China. Water quality index (WQI) stratification was integrated with dissolved organic matter (DOM) fluorescence components, hydrochemical ions, and conventional parameters and analyzed using positive matrix factorization (PMF). Correlation analysis further elucidated source compositions and interactions.

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Objective: CircRNAs are involved in cancer progression. However, their role in immune escape in non-small cell lung cancer (NSCLC) remains poorly understood.

Methods: This study employed RIP-seq for the targeted enrichment of circRNAs, followed by Western blotting and RT-qPCR to confirm their expression.

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Autoimmune encephalitis with Anti-mGluR1 antibodies: a comprehensive review.

J Neurol

September 2025

Department of General Practice, The First People's Hospital of Lin'an District, Hangzhou, Lin'an People's Hospital Affiliated to Hangzhou Medical College, Hangzhou, 310000, Zhejiang Province, China.

Anti-mGluR1 encephalitis is a rare autoimmune disorder manifesting with cerebellar syndrome with varying levels of severity. However, limited data exist regarding the clinical features and treatment strategies for patients suffering from encephalitis associated with anti-mGluR1 antibodies. Herein, we comprehensively review and discuss clinical features of anti-mGluR1 encephalitis to enhance our understanding of this rare disorder.

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Impact of lymph node dissection on survival after neoadjuvant immunochemotherapy for esophageal squamous cell cancer: a double-center real-world retrospective study.

Cancer Immunol Immunother

September 2025

Guangdong Provincial Clinical Research Center for Cancer, State Key Laboratory of Oncology in South China, Department of Thoracic Surgery, Sun Yat-Sen University Cancer Center, Guangdong Esophageal Cancer Institute, Guangzhou, 510060, China.

Background: Previous studies indicated that over-dissection of lymph nodes might impair the efficacy of immunotherapy. This study aims to explore the prognostic value of ypN + status and the impact of lymph node dissection (LND) on survival after neoadjuvant immunochemotherapy (NICT) for esophageal squamous cell cancer (ESCC).

Methods: This double-center retrospective study enrolled 206 consecutive ESCC patients who underwent NICT followed by esophagectomy between 2018 and 2024.

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The rapid development of industry and agriculture has led to a significant increase in the toxicity and pollution of cadmium (Cd) and lead (Pb) in soil. Consequently, soil remediation employing biochar or modified biochar has emerged as a cost-effective and environmentally sustainable approach to address the issue of heavy metal (HM) ion pollution. PEI-functionalization biochar (PBC) derived from corn straw (PBCC), wood straw (PBCW), and rice straw (PBCR) was synthesized to immobilize Cd and Pb in contaminated acidic yellow soil.

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Transition behavior of the waiting time distribution in a stochastic model with the internal state.

J Math Biol

September 2025

School of Mathematical Sciences and Institute of Natural Sciences, MOE-LSC, CMA-Shanghai, Shanghai Jiao Tong University, Shanghai, China.

It has been noticed that when the waiting time distribution exhibits a transition from an intermediate time power-law decay to a long-time exponential decay in the continuous time random walk model, a transition from anomalous diffusion to normal diffusion can be observed at the population level. However, the mechanism behind the transition of waiting time distribution is rarely studied. In this paper, we provide one possible mechanism to explain the origin of such a transition.

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Epizootic hemorrhagic disease virus (EHDV) causes severe disease in ruminants. We assessed the pathogenicity of the Chinese EHDV-7 isolate YN09 in mice lacking the type I interferon receptor and in sheep. In mice, YN09 infection resulted in 100% mortality, with histopathological lesions, viral replication, and immunoreactivity in multiple organs.

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Aberrant DNA methylation has been described in nearly all human cancers, yet its interplay with genomic alterations during tumor evolution is poorly understood. To explore this, we performed reduced representation bisulfite sequencing on 217 tumor and matched normal regions from 59 patients with non-small cell lung cancer from the TRACERx study to deconvolve tumor methylation. We developed two metrics for integrative evolutionary analysis with DNA and RNA sequencing data.

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Chalasoergodimers A-E, heterodimers with multiple polymerization modes from a marine-derived Chaetomium sp. fungus.

Nat Prod Bioprospect

September 2025

College of Pharmaceutical Sciences, Key Laboratory of Medicinal Chemistry and Molecular Diagnostics of Education Ministry of China, State Key Laboratory of New Pharmaceutical Preparations and Excipients, Hebei University, Baoding, 071002, People's Republic of China.

Five new heterodimers, chalasoergodimers A-E (1-5), and three known heterodimers (6-8), along with four chaetoglobosin monomers (9-12), were isolated from a marine-derived Chaetomium sp. fungus. The structures of new compounds 1-5 were elucidated by HRESIMS, NMR, chemical calculated C NMR and ECD methods.

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Automated Facial Aesthetics Evaluation: Performance of the Beauty Scanner-Face Analyzer in Measuring Symmetry and Proportions.

Aesthetic Plast Surg

September 2025

Department of Plastic and Cosmetic Surgery, Tongji Hospital, School of Medicine, Tongji University, No.389 Xincun Road, Shanghai, 200092, China.

Background: The integration of digital tools in aesthetic medicine has enhanced the precision of facial feature analysis. Using concepts like the Golden Ratio, these technologies enable more objective assessments of facial proportions and symmetry. The beauty scanner-face analyzer (BS-FA) app offers a digital approach to evaluate geometric proportions and facial alignment, providing valuable data for preoperative planning in plastic surgery and aesthetic treatments.

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Evaluating the Long-term Effects of Microfocused Ultrasound on Facial Tightening Using Quantitative Instruments: Efficacy and Safety.

Aesthetic Plast Surg

September 2025

Department of Plastic Surgery, The First Affiliated Hospital, Jinan University, No. 613 West, Huangpu Avenue, Guangzhou, 510630, Guangdong Province, China.

Background: Microfocused ultrasound (MFU) is a non-invasive technique used for facial rejuvenation, yet there is limited quantitative data on its long-term effects. This study aimed to evaluate the long-term efficacy and safety of MFU for facial rejuvenation. We utilized standardized photography along with advanced skin assessment technologies to analyze the impact of MFU on facial morphology, skin function, and patient satisfaction over a 12-month period.

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Development of smartphone-based AIE fluorescence-quenching immunochromatographic sensors for the detection of illicit drugs in various complex sample matrices.

Anal Bioanal Chem

September 2025

GuangDong Engineering Technology Research Center of Antibody Drug and Immunoassay, Department of Biological Sciences and Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.

Illicit drug abuse poses a significant global threat to public health and social security, highlighting the urgent need for rapid, sensitive, and versatile detection technologies. To address the limitations of traditional chromatographic techniques-such as high costs and slow response times-and the drawbacks of conventional immunochromatographic sensors (ICS), including low sensitivity and non-intuitive signal outputs, a fluorescence-quenching ICS (FQICS) was developed. This sensor leverages fluorescence resonance energy transfer (FRET) between aggregation-induced emission fluorescent microspheres (AIEFMs) and gold nanoparticles (AuNPs).

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The prompt and accurate identification of pathogenic bacteria is crucial for mitigating the transmission of infections. Conventional detection methods face limitations, including lengthy processing, complex sample pretreatment, high instrumentation costs, and insufficient sensitivity for rapid on-site screening. To address these challenges, an aptamer (Apt)-sensor based on functionalized magnetic nanoparticles (MNPs) was developed for detecting Escherichia coli.

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Proteasome 20S beta 8 (PSMB8) as a metabolic switcher of neuronal ferroptosis in multiple sclerosis.

Cell Death Differ

September 2025

Department of Neurology, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

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RNF128 regulates the adaptive metabolic response to fasting by modulating PPARα function.

Cell Death Differ

September 2025

Graduate Institute of Physiology, College of Biomedical Sciences, National Defense Medical University, Taipei, Taiwan, Republic of China.

Peroxisome proliferator-activated receptor alpha (PPARα) is a crucial transcriptional factor that regulates fatty acid β-oxidation and ketogenesis in response to fasting. However, the mechanisms underlying PPARα function remain unclear. This study identified a novel PPARα-binding protein-RING finger protein 128 (RNF128)-that facilitates PPARα polyubiquitination, resulting in the degradation and suppression of PPARα function during fasting.

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Purpose: This study aimed to investigate the relationship between tissue bridges and bladder and bowel outcomes in chronic cervical spinal cord injury (SCI).

Methods: Between July 2020 and January 2024, 44 patients with chronic cervical SCI were retrospectively included in this cross-sectional study at a specialized SCI center. Lesion severity was assessed by tissue bridges, lesion length, lesion width, and lesion area.

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Purpose: This study aims to assess the outcomes of combining oblique lumbar interbody fusion (OLIF) with anterolateral screw fixation (ASF) and stress endplate augmentation (SEA) in comparison to OLIF combined with pedicle screw fixation (PSF) for the treatment of degenerative lumbar spinal stenosis (DLSS) in patients with osteoporosis (OP).

Methods: We performed a retrospective analysis of patients diagnosed with DLSS who underwent OLIF in conjunction with either SEA and ASF (SEA-ASF group) or PSF (PSF group). Clinical outcomes, including the visual analog scale (VAS) scores for lumbar and leg pain, as well as the Oswestry Disability Index (ODI), were assessed at various postoperative intervals and compared to preoperative values.

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Purpose: To write a letter to editors concerning "Efficacy of two opportunistic methods for screening osteoporosis in lumbar spine surgery patients" by T.-T. Xu, et al.

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Immune checkpoint inhibitors combined with chemotherapy in conversion therapy for stage IV gastric cancer: a multicenter retrospective cohort study.

Cancer Immunol Immunother

September 2025

Department of Gastric Surgery, Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Hangzhou, 310022, Zhejiang, China.

Objectives: To evaluate the efficacy of combining PD-1 inhibitors with chemotherapy in conversion therapy for patients with stage IV gastric cancer and to determine the populations most likely to benefit from this regimen.

Methods: Data from patients with stage IV gastric cancer who received conversion therapy with PD-1 inhibitors combined with chemotherapy between January 2018 and December 2022 at multiple centers were retrospectively reviewed. Patients who underwent conversion surgery were categorized into a surgery group, while those who did not were placed into a palliative group.

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Dietary lignan intake and body fat distribution in U.S. adolescents.

Pediatr Res

September 2025

Department of Digestive & Nutrition, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China.

Background: Body fat distribution patterns impact adolescent health, yet research on dietary lignans' influence remains limited. This study investigated their association among U.S.

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