Bird habitat network construction in Shenyang City based on improved circuit theory of neighborhood landscape compatibility.

Constructing urban habitat networks can effectively improve the stability of regional ecosystems, increase energy flow and gene exchange in landscape patches, and play a crucial role in urban biodiversity conservation. With urban area of Shenyang City as the study area, we identified the source of bird habitats from three dimensions: morphology-quality-neighborhood. From the three dimensions of environmental elements, architectural index, and anthropogenic interference, we superimposed 12 resistance factors to construct resistance surfaces.

High-quality narrow black phosphorus nanoribbons with nearly atomically smooth edges and well-defined edge orientation.

Black phosphorus nanoribbons (BPNRs) with a tunable bandgap and intriguing electronic and optical properties hold strong potential for logic applications. However, efficiently producing high-quality BPNRs with precise control over their size and structure remains a great challenge. Here we achieved high-quality, narrow and clean BPNRs with nearly atomically smooth edges and well-defined edge orientation at high yield (up to ~95%) through the sonochemical exfoliation of the synthesized bulk BP crystals with a slightly enlarged lattice parameter along the armchair direction.

Mobile and Wireless Autofluorescence Detection Systems and Their Application for Skin Tissues.

Skin autofluorescence (SAF) detection technology represents a noninvasive, convenient, and cost-effective optical detection approach. It can be employed for the differentiation of various diseases, including metabolic diseases and dermatitis, as well as for monitoring the treatment efficacy. Distinct from diffuse reflection signals, the autofluorescence signals of biological tissues are relatively weak, making them challenging to be captured by photoelectric sensors.

Magneto-optical Effect of Dark State in 0D Metal Halides through HT/FC Vibrational Coupling.

Dark excitonic states play a pivotal role in controlling the radiative dynamics of low-dimensional luminescent materials. In this work, we investigate dark states of an emerging zero-dimensional (0D) organic-inorganic hybrid metal halide that diverge markedly from traditional inorganic and organic semiconductors. Our studies reveal that when the dark states dominate the emission, the 0D material exhibits an anomalous giant magneto-blueshift of approximately 9 meV at 7 T.

Controlling aggregation-induced emission of iridium(Ⅲ) complexes via molecular hydrophilic-lipophilic interactions and in-situ electrostatic self-assembly.

Exploring the internal relationship between the structure and properties of AIE-active iridium complexes and their applications have been great significance. It is imperative to acknowledge that the precise control of nanoparticle morphology and particle size of organic molecules in solutions remains elusive, while comprehending the luminescent mechanisms of self-assembled aggregates continues to present a challenge. The previously work proposed that solvent-induced amphiphilic molecules could enhance the self-assembly properties of iridium complexes, but the influence of ligands' hydrophilic-lipophilic interactions on the AIE characteristics of iridium complexes remained unclear.

The Association Between Sensory Impairment and Cognitive Impairment Among Older Adults: Insights From a National Cohort Study in China.

Objectives: Cognitive impairment and sensory impairment are highly prevalent in older adults, but the relationship between the two remains inconclusive. This study aimed to investigate the relationship between visual impairment (VI), hearing impairment (HI), dual sensory impairment (DSI), and the onset of cognitive impairment among Chinese older adults.

Methods: Data were obtained from the 2011-2018 China Longitudinal Healthy Longevity Survey (CLHLS) cohort.

Winnow-KAN: single-cell RNA-seq location recovery with small-gene-set spatial transcriptomics.

Unlabelled: Keywords: Cell mapping, Deep Learning, Kolmogorov-Arnold network, Single-cell RNA-seq, Spatial transcriptomics. Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular heterogeneity. However, its collection process prevents the investigation of tissue organization due to the lack of spatial origins for the cells.

Anisotropic High Carrier Mobility in Violet Phosphorus.

Violet phosphorus (VP), with its high carrier mobility, is a promising candidate for next-generation optoelectronic devices. Its anisotropic structure, polarization sensitivity, high photoelectric efficiency, and tunable bandgap enable diverse optical responses, making it ideal for applications such as photodetectors, neural networks, and multimodal systems. However, the basic anisotropic transport properties have not been experimentally revealed.

BEA-CACE: branch-endpoint-aware double-DQN for coronary artery centerline extraction in CT angiography images.

Purpose: In order to automate the centerline extraction of the coronary tree, three challenges must be addressed: tracking branches automatically, passing through plaques successfully, and detecting endpoints accurately. This study aims to develop a method to solve the three challenges.

Methods: We propose a branch-endpoint-aware coronary centerline extraction framework.

Co-Selection of Low Cadmium Accumulation and High Yield During Tomato Improvement.

Enhancing crop production and yield is necessary to feed an increasing population, but cadmium (Cd) accumulation in crops poses a serious threat to human health. It is found that a trend during domestication is for the co-selection of improved tomato yield and reduced Cd accumulation. A genome-wide association study (GWAS) of 506 tomato accessions identifies a natural allele, LCT1, which confers low Cd accumulation in the shoots and fruits of tomato.

Integration of GWAS and transcriptome approaches for the identification of nitrogen-, phosphorus-, and potassium-responsive genes in tomato.

Plant growth is inseparable from the presence of mineral nutrients such as nitrogen (N), phosphorus (P), and potassium (K), but the mechanism by which horticultural plants such as tomatoes respond to mineral elements is poorly understood. Here, we collected 28 phenotypic datasets, including 5 agronomic traits and 4 pigment accumulation traits, under full nutrition and nitrogen/phosphorus/potassium-deficiency conditions, most of which showed abundant variation. Phenotyping analysis suggested that the yellowing of leaves under low-nitrogen treatment was caused by an increase in the carotenoid content and a decrease in the chlorophyll content.

Exploring the impact of follicular fluid exosomes on porcine cumulus cell and oocyte function: Regulatory network analysis based on the ENSSSCG00000042788/ssc-miR-504/PDHA1 axis.

The development and maturation of mammalian oocytes are crucial stages in reproduction, directly influencing embryo health and the genetic quality of offspring. Follicular fluid serves as the microenvironment for oocyte development, with exosomes playing a key role in regulating the activities of cumulus cells and oocytes. However, the mechanisms governing porcine oocyte maturation remain incompletely understood.

Ubiquitin-mediated immunoglobulin-binding protein 1 degradation promotes autophagy and sperm capacitation in vitro.

Background: During sperm capacitation, post-translational modifications such as SUMOylation are crucial for maintaining protein homeostasis. Macroautophagy (autophagy) is essential for cellular and energy homeostasis, aiding in the survival of reproductive cells and protecting against ovarian aging. However, the role of autophagy in capacitated sperm remains unclear.

Development and Validation of a Dynamic Online Nomogram Prediction Model for Assessing the Risk of Erectile Dysfunction.

Purpose: Erection dysfunction (ED) represents a globally prevalent men's health problem and affected by a variety of factors. This study aimed to develop a dynamic nomogram model to assess the probability of ED in a population through a multitude of factors.

Materials And Methods: A total of 2,668 subjects from the National Health and Nutrition Examination Survey were included in this study.

Transformer-Based Air-to-Ground mmWave Channel Characteristics Prediction for 6G UAV Communications.

With the increasing development of 6th-generation (6G) air-to-ground (A2G) communications, the combination of millimeter-wave (mmWave) and multiple-input multiple-output (MIMO) technologies can offer unprecedented bandwidth and capacity for unmanned aerial vehicle (UAV) communications. The introduction of new technologies will also make the UAV channel characteristics more complex and variable, posing higher requirements for UAV channel modeling. This paper presents a novel predictive channel modeling method based on Transformer architecture by integrating data-driven approaches with UAV air-to-ground channel modeling.

A systematic review and meta-analysis of artificial intelligence software for tuberculosis diagnosis using chest X-ray imaging.

Background: Pulmonary tuberculosis (PTB) remains a global public health challenge, with 10.8 million new cases reported in 2023. Early diagnosis is crucial for controlling its spread, yet traditional sputum-based tests face limitations in turnaround time and resource availability.

Near-Infrared Biosensing of Drug-Induced Cell-Heterogeneous Injuries with an Ultrahigh Turn-On Ratio.

Fluorescence probes of reactive oxygen species in the near-infrared (NIR) spectral region, i.e., 800 nm and beyond, are desired for in vivo biosensing, diagnosis, and pharmacology.

Advancements in the Research on the Preparation of Isoamyl Acetate Catalyzed by Immobilized Lipase.

This study aims to delve into the application potential of immobilized lipases in the catalytic synthesis of isoamyl acetate. Through a comparative analysis of various immobilization methods, including physical adsorption, encapsulation, covalent binding, and crosslinking, along with the utilization of nanomaterials, such as magnetic nanoparticles, mesoporous silica SBA-15, and covalent organic frameworks (COFs) as carriers, the study systematically evaluates their enhancing effects on lipase catalytic performance. Additionally, solvent engineering strategies, encompassing the introduction of organic solvents, supercritical fluids, ionic liquids, and deep eutectic solvents, are employed to intensify the enzymatic catalytic process.

Exploring the influence of pulmonary pathological state on the in vivo fate of inhaled microparticles with different structural characteristics.

Currently, marketed inhalation products for treatment of pulmonary arterial hypertension (PAH) have limited time of action due to pulmonary clearance mechanism and short of sustained-release characteristics. Meanwhile, little is known on how the pathological state of PAH affects the in vivo fate of inhaled microparticles. Thus, the objective of this study is to elucidate the influence of pulmonary pathological state on the in vivo behavior of inhaled microparticles with different structural characteristics.

Sensitive, selective, and pretreatment-free detection of ferric ions in different solvents based on organic-soluble carbon dots.

The presence of ferric ion (Fe) impurities can reduce the stability and efficiency of organic solvents, which can significantly impact the production of chemicals, food, medical supplies, and daily necessities. Herein we describe the synthesis of organic-soluble carbon dots (CDs) and their first application for Fe detection in various organic solvents without requiring pretreatment procedures. The CA-CDs were prepared a solvothermal method using caffeic acid (CA) as a precursor and anhydrous ethanol as the solvent.

miR-126-loaded ZIF-8 nanoparticles as a dual-functional approach for accelerating vascularized bone regeneration.

Background: Bone defects pose a significant clinical challenge due to their high morbidity and long-term disability. Simultaneous enhancement of osteogenesis and angiogenesis holds promise for accelerating bone regeneration. MicroRNAs (miRNAs), particularly miR-126, are critical regulators of angiogenesis; however, their therapeutic application requires efficient delivery systems.

Exogenous Thiamine Regulates Multiple Plant Immunity-Associated Pathways to Inhibit MCMV Infection.

Thiamine, also known as vitamin B1, serves as an inducer that strengthens plants and elicits defense responses to enhance resistance against pathogens. Currently, the antiviral mechanism of thiamine remains unclear. Here, we used maize chlorotic mottle virus (MCMV) as a model to elucidate the antiviral mechanism of thiamine.

Repellent Activity of DEET and Biont-Based Mosquito Repellents in the Chinese Market Against the Asian Long-Horned Tick, .

To investigate the repellent efficacy of commercially available mosquito repellents in China against , four representative DEET-based repellents and biont-derived repellents were selected. This study utilized a modified circular filter paper method repellent testing device to establish an evaluation system for assessing the repellent effects of each product against three developmental stages of : larvae, nymphs, and adults. In our study, for DEET-based repellents, Johnson demonstrated the highest repellency against larvae within 1 h, with an average repellency rate exceeding 80.

RNAi targeting heparin cofactor II promotes hemostasis in a canine model of acquired hemophilia A.

Heparin cofactor II (HCII) is a critical anticoagulant protein that inactivates thrombin. In our previous mouse studies, we demonstrated that GalNAc-HCII, a small interfering RNA (siRNA) targeting HCII conjugated with N-acetylgalactosamine (GalNAc), exhibited promising therapeutic effects in hemophilia A mouse models. Further evaluation in large animal models, especially with FVIII inhibitors, is essential before GalNAc-HCII can proceed to clinical trials.

Innovations in smart enzyme biosensors: Advancing the detection of antibiotic residues in aquaculture.

In aquaculture, the presence of antibiotic residues is an escalating concern that poses significant risks to human health. Establishing efficient and user-friendly detection methods for antibiotic residues has become crucial to mitigate these potential hazards. To address the limitations of traditional techniques, novel enzyme biosensors, offering high sensitivity and specificity and rapid response, has been introduced for monitoring a wide range of antibiotics in food safety applications.