Rational design of freeze-crosslinked polysaccharide sponges for efficient non-compressible hemostasis and liver repair.

Non-compressible hemorrhage is a life-threatening challenge, and shape-memory hemostatic sponges that require no removal are ideal for inaccessible hemorrhage wounds. In this study, we freeze-crosslinked two polysaccharides by tuning their ratios to fully utilize their inherent physiochemical properties. The obtained shape memory sponges exhibit tunable mechanical properties, high absorbent capacities, and compression resilience.

Subcritical fluid and molecular distillation extraction of lipid and its metabolic benefits in hyperlipidemic mice.

The marine microalga is a fast-growing species rich in long-chain polyunsaturated fatty acids (PUFAs), particularly eicosapentaenoic acid (EPA), and other bioactive compounds. In this study, lipids from powder were extracted and refined using subcritical butane combined with molecular distillation to obtain a highly purified lipid extract with increased EPA concentration (58.92% w/w) and improved biological activity.

The Super Anti-Browning Effect of High-Oxygen Pretreatment Combined with Cod Peptides on Fresh-Cut Potatoes During Storage.

Enzymatic browning poses a formidable obstacle to the commercial sustainability of fresh-cut potatoes. Although the synergistic effects of bio-inductive technologies with natural compounds in anti-browning strategies have been observed, their full potential remains underexplored. To fulfill the demand for synergistic approaches in real-world applications, this research elucidates the complementary effects of short-term high-oxygen (HO, 80%) treatment of whole tubers in conjunction with cod peptides (CP, 0.

Pickering emulsion gel stabilized by milk fat globule membrane/pectin enhanced probiotic stability.

The milk fat globule membrane (MFGM) has been shown to improve probiotic survival in the gastrointestinal tract. However, emulsions stabilized through electrostatic interactions between MFGM and polysaccharides for probiotic encapsulation remain unexplored. This study established optimal conditions for creating MFGM-Pectin (CP) emulsions.

Superior peroxidase-like activities of InVO hollow nanocuboid assemblies for colorimetric detection of hydrogen peroxide and glucose.

In this work, InVO hollow nanocuboid assemblies (IVHNs) with larger specific surface area were synthesized by a facile one-pot hydrothermal method, which were utilized as artificial biomimetic catalysts. In the presence of hydrogen peroxide (HO), the IVHNs nanozyme enchantingly displayed an extraordinary peroxidase-like performance, inducing the oxidation of the chromogenic compound 3,3',5,5'-tetramethylbenzidine (TMB) to generate a blue oxide. Kinetics analysis unequivocally demonstrated that the catalytic behavior of IVHNs conformed to the Michaelis-Menten mechanism, and ·O radicals played a vital role in the catalytic process according to the active species capture experiments.

Power of Multi-Modality Variables in Predicting Parkinson's Disease Progression.

Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The increasing demand for high-accuracy forecasts of disease progression has led to a surge in research employing multi-modality variables for prediction. In this review, we selected articles published from 2016 through June 2024, adhering strictly to our exclusion-inclusion criteria.

Is it possible to obtain substitutes for human milk oligosaccharides from bovine milk, goat milk, or other mammal milks?

Considering the current level of chemical and biological synthesis technology, it was a sensible selection to obtain milk oligosaccharides (MOs) from other mammals as the potential substitute for human MOs (HMOs) that possessed various structural features in the infant formula. Through a comprehensive analysis of the content, structure, and function of MOs in six distinct varieties of mammal milk, it has been shown that goat milk was the most suitable material for the preparation as a human milk substitute. Goat MOs (GMOs) had a relatively high content and diverse structural features compared to those found in other mammalian milks.

Research progress on microbial adsorption of radioactive nuclides in deep geological environments.

Due to the development and utilization of nuclear energy, the safe disposal of nuclear waste needs to be urgently addressed. In recent years, the utilization of microorganisms' adsorption capacity to dispose of radioactive waste has received increasing attention. When compared with conventional disposal methods, microbial adsorption exhibits the characteristics of high efficiency, low cost, and no secondary pollution.

A synbiotic formulation of and inulin alleviates ASD-like behaviors in a mouse model: the mediating role of the gut-brain axis.

Autism Spectrum Disorder (ASD), a complex neurodevelopmental disorder marked by social communication deficits and repetitive behaviors, may see symptom amelioration through gut microbiota modulation. This study investigates the effects of a synbiotic - specifically a probiotic amplified by prebiotic supplementation - on ASD-like mouse model's social deficiencies. This model was established valproic acid injection into pregnant females.

A new research proposal to prevent hydrogen embrittlement for nuclear waste container by bacteria-a mini review.

A large amount of nuclear waste produced in the process of nuclear energy utilization has always been a key problem to be solved urgently for nuclear safety. At present, "deep geological disposal" is a feasible method and generally accepted by many countries. The oxygen content in the near field environment of the waste container will decrease to anaerobic conditions, and hydrogen will permeation into the internal materials of container for a long time.

Sesamol Mitigates Chronic Iron Overload-Induced Cognitive Impairment and Systemic Inflammation via IL-6 and DMT1 Regulation.

Scope: Excessive iron contributes to oxidative damage and cognitive decline in Alzheimer's disease. Sesamol, a compound in sesame oil that exhibits both anti-inflammatory and neuroprotective properties, is examined in this study for its ability to alleviate cognitive impairments in iron overload mice model.

Methods And Results: An iron overload model is established by intraperitoneally injecting dextran iron (250 mg kg body weight) twice a week for 6 weeks, while sesamol (100 mg kg body weight) is administered daily for the same length of time.

Impact of age-friendly living environment and intrinsic capacity on functional ability in older adults: a cross-sectional study.

Background: The World Health Organization (WHO) has proposed healthy aging framework, supposing that intrinsic capacity (IC), environment and their interaction may have influence on functional ability (FA). It was still unclear how the IC level and age-friendly living environment impact on FA. This study aims to confirm the relationship between the IC level and age-friendly living environment with FA, especially in older adults with low IC.

Medullary cavity application of tranexamic acid to reduce blood loss in tibial intramedullary nailing procedures-a randomized controlled trial.

Purpose: Studies have shown an average postoperative hidden blood loss (HBL) of 473.29 ml and an average Hb loss of 16.71 g/l after intramedullary nailing.

Effects of ageing time on the properties of polysaccharide in tangerine peel and its bacterial community.

To evaluate the effect of aging time on the quality of tangerine peel (TP) from the perspective of TP polysaccharide (TPP), five polysaccharide samples with different aging times named TPP-0/1/5/10/15 were prepared. Under the conditions of pH 0.5, solid-liquid ratio 1:25 and 80 °C, the TPPs extraction yield ranged from 20.

Neural circuits underlying language control and modality control in bilinguals: An fMRI study.

Human communication not only involves the need to switch between the modalities of speaking and listening, but for bilinguals, it can also involve switching between languages. It is unknown as to whether modality and language switching share underlying control mechanisms or whether one type of switching affects control processes involved in the other. The present study uses behavioral and fMRI measures to examine neural circuits of control during communicative situations that required Chinese-English bilinguals to switch between modalities and their two languages according to associated color cues.

Flexor carpi radialis brevis muscle, a rare anomalous muscle of the forearm; a case report and literature review.

The flexor carpi radialis brevis (FCRB) is a rare abnormal muscle of the distal forearm or wrist. Its incidence varies in different reports, which oscillating between 2-8%. This paper reports a case of FCRB found in the anatomy of the forearm.

Comparative prospective randomized study of minimally invasive transpiriformis approach versus conventional posterolateral approach in total hip arthroplasty as measured by biology markers.

Background: Minimally invasive surgery is becoming increasingly common, but evidence of the advantages of the minimally invasive transpiriformis approach in total hip arthroplasty is limited. Therefore, our single-centre randomized controlled trial evaluated the benefits of this approach versus the posterolateral approach.

Methods: Forty-nine patients undergoing the minimally invasive transpiriformis approach and 57 patients undergoing the posterolateral approach total hip arthroplasty were analyzed.

Newly graduated nurses' perceptions of work environment: A cross-sectional study in China.

Aim: To assess the attitudes of newly graduated nurses in China toward their work environment and identify the factors affecting their perception.

Background: Newly graduated nurses are the primary supply to cover the nursing shortage, but their stressful transition into clinical work has contributed to high turnover for decades. Although serving as a source of stress, the work environment can also be a source of support for new nurses.

High resolution computed tomography for the diagnosis of 2019 novel coronavirus (2019-nCoV) pneumonia: a study from multiple medical centers in western China.

Background: To evaluate the role of high-resolution computed tomography (HRCT) in the diagnosis of 2019 novel coronavirus (2019-nCoV) pneumonia and to provide experience in the early detection and diagnosis of 2019-nCoV pneumonia.

Methods: Seventy-two patients confirmed to be infected with 2019-nCoV from multiple medical centers in western China were retrospectively analyzed, including epidemiologic characteristics, clinical manifestations, laboratory findings and HRCT chest features.

Results: All patients had lung parenchymal abnormalities on HRCT scans, which were mostly multifocal in both lungs and asymmetric in all patients, and were mostly in the peripheral or subpleural lung regions in 52 patients (72.

Tranexamic acid safely reduces hidden blood loss in patients undergoing intertrochanteric fracture surgery: a randomized controlled trial.

Purpose: To investigate the efficacy and safety of intravenous tranexamic acid (IV-TXA) in patients undergoing intertrochanteric fracture surgery.

Methods: A total of 122 patients were included in this double-blinded trial and equally randomized to receive 1 g of IV-TXA or normal saline 10 min before incision and 3 h later. The primary efficacy outcome was calculated hidden blood loss (HBL).

Pichia kudriavzevii retards fungal decay by influencing the fungal community succession during cherry tomato fruit storage.

In this study, P. kudriavzevii was isolated and identified as an effective antagonistic yeast, which could significantly inhibit the rotting rate, weight loss, and delay the color change, with no effect on total soluble solids (TSS), titratable acid (TA), or firmness during cherry tomato storage. High-throughput sequencing was used to survey the effect of P.

Is intravenous tranexamic acid effective and safe during hip fracture surgery? An updated meta-analysis of randomized controlled trials.

Introduction: The efficacy and safety of intravenous (IV) tranexamic acid (TXA) during hip fracture surgery remain controversial. This meta-analysis aimed to assess the efficacy of IV-TXA administration during hip fracture surgery for reducing the transfusion requirement and blood loss as well as its safety regarding the risk of thrombolysis.

Materials And Methods: PubMed, EMBASE, Web of Science, and the Cochrane Library Database were systematically searched for randomized controlled trials (RCTs) that focused on the efficacy and safety of IV-TXA in patients during hip fracture surgery.

Highly Sensitive p + n Metal Oxide Sensor Array for Low-Concentration Gas Detection.

Nowadays, despite the easy fabrication and low cost of metal oxide gas sensors, it is still challenging for them to detect gases at low concentrations. In this study, resistance-matched p-type Cu₂O and n-type Ga-doped ZnO, as well as p-type CdO/LaFeO₃ and n-type CdO/Sn-doped ZnO sensors were prepared and integrated into p + n sensor arrays to enhance their gas-sensing performance. The materials were characterized by scanning electron microscopy, transmittance electron microscopy, and X-ray diffractometry, and gas-sensing properties were measured using ethanol and acetone as probes.

Polychlorinated biphenyls and polybrominated diphenylethers in soils from planted forests and adjacent natural forests on a tropical island.

Transformation from natural forests to planted forests in tropical regions is an expanding global phenomenon causing major modifications of land cover and soil properties, e.g. soil organic carbon (SOC).