Gut microbiota dysbiosis exacerbates polystyrene microplastics-induced liver inflammation via activating LPS/TLR4 signaling pathway in ducks.

Ubiquitous microplastics can bioaccumulate in organisms, resulting in detrimental health impacts, such as liver inflammation. Nonetheless, the exact mechanism by which polystyrene microplastics (PS-MPs) trigger liver inflammation via the gut-liver axis in ducks remains unclear. The purpose of this study was to clarify the impact of PS-MPs exposure to liver inflammation through the gut-liver axis in ducks.

The emotional equation: how psychosocial support boosts safety practices in the context of construction 5.0.

Background: Construction 5.0, which emphasizes human-centric technologies and improved collaboration between humans and machines in intelligent construction ecosystems, introduces distinct safety management challenges that necessitate effective emotional resource allocation strategies. This study utilizes job demands-resources theory to investigate how emotional resources are allocated for safety management by examining the relationships among safety practice, psychosocial support, safety participation, and leadership safety behavior.

Investigating the correlation between phenotype, cecal microbiome, and serum metabolome in laying ducks with different shell strength.

Eggshell quality plays a critical role in the poultry industry, influencing both biological and economic outcomes. However, the factors determining eggshell strength in egg-laying ducks remain poorly understood. This study sought to explore phenotypic variations, gut microbiota composition, and serum metabolites in ducks with differing eggshell strengths to identify key microbial and metabolic factors affecting shell integrity.

Cytogenetic characterization of a novel wheat-rye 2R (2D) substitution line YT9 conferring powdery mildew resistance from the three-leaf stage and physical mapping of PmYT9.

A wheat-rye 2R (2D) substitution line with PmYT9 conferring powdery mildew resistance was characterized. PmYT9 was mapped to a 14. 55 Mb interval on 2RL.

Polystyrene microplastics exacerbate mitophagy through mitochondrial dysfunction in the duck lung.

Microplastics (MPs) are widespread environmental pollutants that can enter the human body through the food chain, potentially leading to lung damage. However, the underlying mechanisms responsible for this damage remain unclear. Ducks, a commonly consumed poultry species in China, are particularly susceptible to MPs exposure due to their farming environment.

Influence of fermented feed on lipid composition and volatile flavor profile of duck eggs: Insights from multi-omics analysis.

This study employed a multi-omics approach to examine the impact of feed fermentation on the lipid profile and volatile flavor of duck eggs. Sensory evaluation and GC × GC-TOFMS analyses demonstrated that microbial fermentation in feed significantly reduced the off-odor of duck eggs. Among the thirty-nine differential volatile compounds identified, six-namely 3-methylbutanal, 1-octen-3-ol, hexanal, acetophenone, 2-heptanone, and 2-pentylfuran-were likely responsible for the alteration in yolk aroma.

Glacial retreat and climate change: insights from remote sensing technologies.

Glaciers and ice sheets, vital components of the Earth's climate system and crucial freshwater sources, are rapidly retreating under the influence of climate change. This study reviews the use of remote sensing technologies in monitoring these changes, highlighting tools like Synthetic Aperture Radar (SAR) and satellite imagery from Landsat and MODIS. These technologies provide detailed measurements of ice dynamics, revealing substantial regional variability in ice loss, particularly in the Arctic and Antarctic.

Dietary resveratrol alleviates liver and intestinal injury in ducks under cage rearing system.

Cage rearing is a promising farming method. However, our previous studies have demonstrated that changes in farming practices induce oxidative stress and inflammation in the liver and duodenum of ducks. Resveratrol (RES), a natural plant polyphenol, possesses antioxidant, anti-inflammatory, and cytoprotective properties.

Comparative Transcriptome Profiling of Ileal and Cecal Tissues Between Pekin Ducks and Shaoxing Ducks.

: Pekin ducks are well-known meat-type ducks, whereas Shaoxing ducks are bred for their egg-laying abilities. Growth and development of poultry species is well studied; however, very little is known regarding differences in intestinal gene expression between Pekin and Shaoxing ducks. : To investigate intestinal differences between Pekin and Shaoxing ducks, we conducted transcriptome analysis on ileal and cecal tissues from five 42-day-old ducks per breed, raised under identical housing and feeding conditions to minimize environmental influences.

Exploring the Dietary Strategies of Coated Sodium Butyrate: Improving Antioxidant Capacity, Meat Quality, Fatty Acid Composition, and Gut Health in Broilers.

Background/objectives: Broiler chickens are excellent animals for protein production and play an essential role in the food industry. The purpose of this study is to investigate the effect of coated sodium butyrate (CSB) on the biochemical indices, antioxidant capacity, meat quality, fatty acid composition, and gut health of Xianju broilers.

Methods: A total of 192 one-day-old broilers were randomly divided into four treatment groups: the basal diet (CK), the basal diet with 250 mg/kg CSB (CSB250), the basal diet with 500 mg/kg CSB500 (CSB500), and the basal diet with 1000 mg/kg CSB (CSB1000).

Interaction between cecal microbiota and liver genes of laying ducks with different residual feed intake.

Background: The gut microbiota exerts a critical influence on energy metabolism homeostasis and productive performance in avian species. Given the diminishing availability of arable land and intensifying competition for finite resources between livestock production and human populations, the agricultural sector faces dual imperatives to enhance productive efficiency while mitigating ecological footprints. Within this paradigm, optimizing nutrient assimilation efficiency in commercial waterfowl operations emerges as a strategic priority.

New insights into ovarian regression-related mitochondrial dysfunction in the late-laying period.

Duck egg production sharply decreases during the late-laying period, which likely stems from an ovarian mechanism. However, the molecular mechanisms underlying ovarian regression during the late-laying period remain unclear. In this study, egg-laying (LLP) and ceased-laying (CLP) ducks at 72 weeks of age were selected to explore the potential mechanism of ovarian regression.

Multi-omics elucidates the kidney damage caused by aquatic Cu via the gut-kidney axis in ducks.

Copper (Cu) is an essential trace element for biological growth and development. Excessive intake of Cu exists harmful effects on organisms. However, whether excessive Cu intake induces kidney function damage by gut microbiota regulation remains unclear.

Cell-free epigenomes enhanced fragmentomics-based model for early detection of lung cancer.

Background: Lung cancer is a leading cause of cancer mortality, highlighting the need for innovative non-invasive early detection methods. Although cell-free DNA (cfDNA) analysis shows promise, its sensitivity in early-stage lung cancer patients remains a challenge. This study aimed to integrate insights from epigenetic modifications and fragmentomic features of cfDNA using machine learning to develop a more accurate lung cancer detection model.

A new polymer with rich carbonyl delocalized π-conjugated structure for high-performance aqueous zinc ion batteries.

The development of sustainable and clean energy has become a top priority, driven by global carbon peaking and carbon neutrality targets. Organics are widely used in aqueous zinc ion batteries (AZIBs) due to their environmental friendliness, high structural designability, and safety. However, organic materials often face some challenges, including high solubility, low specific capacity, and unclear mechanism, which hinder its further applications.

The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome.

Duck meat has a unique taste and nutritional value, but age probably affects meat quality. In this study, ducks of different ages (60-day-old, D60; 900-day-old, D900) were chosen, and the odor, taste, amino acid, nucleotide, and free fatty acid components of breast meat were evaluated to investigate the differences. The results showed that the amino acid contents of breast muscle in D900 ducks, especially in Asp (umami) and Thr (sweet), were richer than those in D60 ducks.

Effects of combined use of compound acidifiers and plant essential oils in feed on the reproductive performance and physiological status of Xianjv chickens.

This study investigates the effects of combined compound acidifiers and plant essential oils on the production performance, egg quality, and health parameters of Xianjv chickens. A total of 240 healthy 34-week-old Xianjv chickens were randomly divided into 5 groups and given 5 different feed additives: a control group with a basal diet, and four experimental groups with varying doses of compound acidifiers (CA) and essential oils (EO). The results revealed that the addition of compound acidifiers and essential oils did not significantly affect average daily feed intake, egg production rate, or feed-to-egg ratio.

An enhanced dynamic-network-based framework for quantifying and enhancing the resilience of disaster response networks to old communities under rainstorm waterlogging.

Developing effective disaster response networks (DRNs) is crucial for mitigating the impacts of rainstorm waterlogging in old communities. Aiming at providing implementable strategies for enhancing DRN resilience, this paper developed an enhanced dynamic network analysis (DNA)-based framework for DRNs utilizing the DNA and CRITIC-VIKOR method. This framework conceptualizes community disaster response as a three-stage 'agent-information-resource-task' (A-I-R-T) dynamic network, facilitating a comprehensive understanding of interactions among stakeholders, disaster information, emergency resources, and response tasks.

Two-Dimensional π-d Conjugated Conductive Metal-Organic Framework with Triple Active Centers as High-Performance Cathodes for Flexible Zinc Batteries.

Conductive metal-organic frameworks (C-MOFs) have received extensive interest in high-performance zinc-ion batteries (ZIBs) owing to multi-redox sites and high electrical conductivity. Here, we present a π-d C-MOF by coordinating 2,3,5,6-tetraaminobenzoquinone (TABQ) ligands with Cu ions (2D Cu-TABQ) acting as cathodes for ZIBs. Benefiting from a triple active center (Cu, C=O, and C=N), 2D Cu-TABQ shows an ultra-high reversible capacity of 297.

CRM-scaffolded vaccines designed by epitope grafting ameliorate cognitive decline in an Alzheimer's disease model.

Alzheimer's disease (AD) is the leading cause of dementia in the elderly. Amyloid-beta (Aβ) plaque accumulation and tau neurofibrillary tangles (NFTs) formation in the brain are major neuropathological hallmarks of AD. Immunotherapies targeting Aβ and/or tau are deemed the most promising approaches for AD.

Unraveling the gut microbiota of Tibetan chickens: insights into highland adaptation and ecological advantages.

Unlabelled: Tibetan animals have several unique advantages owing to the harsh ecological conditions under which they live. However, compared to Tibetan mammals, understanding of the advantages and underlying mechanisms of the representative high-latitude bird, the Tibetan chicken (, TC), remains limited. The gut microbiota of animals has been conclusively shown to be closely related to both host health and host environmental adaptation.

Integrated omics analysis reveals the differentiation of intestinal microbiota and metabolites between Pekin ducks and Shaoxing ducks.

Pekin ducks and Shaoxing ducks are 2 Chinese local duck breeds, both domesticated from mallard, but after domestication and long-term artificial selection, the body weight of Pekin ducks is significantly higher than that of Shaoxing ducks. It is no debate that genetic factors are the main factors responsible for this difference, but whether intestinal microbiota contribute to this difference is yet unknown. Thus, we performed comparative intestinal metagenomics and metabolomics analysis between Pekin ducks and Shaoxing ducks.

Characterization of a Powdery Mildew Resistance Gene in Wheat Breeding Line Jingzi 102 Using Bulk Segregant RNA Sequencing.

Wheat ( L.) is one of the most important crops worldwide. Powdery mildew caused by f.

The Effects of Resveratrol and Apigenin on Jejunal Oxidative Injury in Ducks and on Immortalized Duck Intestinal Epithelial Cells Exposed to HO.

Oxidative stress increases the apoptosis of intestinal epithelial cells and impairs intestinal epithelial cell renewal, which further promotes intestinal barrier dysfunction and even death. Extensive evidence supports that resveratrol and apigenin have antioxidant, anti-inflammatory, and antiproliferative properties. Here, we investigated the ability of these two compounds to alleviate diquat-induced jejunal oxidative stress and morphological injury, using the duck as a model, as well as the effects of apigenin on oxidative stress induced by HO in immortalized duck intestinal epithelial cells (IDECs).