High Capacity and Efficient Adsorption of Lutetium(III) by the Metal-Organic Framework HKUST-1 in Simulated Medical Wastewater.

Lutetium (Lu(III)), a heavy rare earth element, plays a critical role in advanced industrial processes and nuclear medicine applications. Given its high economic value and potential environmental risks, the recovery of Lu(III) from medical wastewater is both necessary and urgent. However, previous studies on the adsorption behavior of Lu(III) have been limited by low adsorption capacity, competition from coexisting metal ions, and the influence of environmental temperature.

Exploration of the decontamination of common nonmetallic materials by Ce(IV)/HNO3.

With the rapid development of the nuclear medicine business worldwide, the removal of iodine-131 from specific contaminated environments to protect public health has important application prospects. In this study, the surface decontamination mechanism of Ce(IV)/HNO3 as a decontaminant for iodine-131-contaminated nonmetallic materials was investigated by using an orthogonal experimental method and scanning electron microscopy (SEM). During the preparation experiments with the contaminated materials, both quartz glass and ceramics reached peak activity concentration levels at 4 h of adsorption (contamination) by using immersion; the decontamination factor (DF) was selected as the test index for the decontamination experiments.

Compensatory roles of STT3A and ALG5 in glucose metabolism of aged macaque hippocampus.

The hippocampus (HC), a central hub for memory and cognition, exhibits unique metabolic resilience during aging despite widespread brain glucose hypometabolism. Here, we report that aged humans and macaques paradoxically display elevated HC glucose uptake (18F-FDG PET SUVR) alongside strengthened connectivity to sensory-motor and limbic networks-an adaptive rewiring revealed by graph-theoretical metabolic network analysis. Integrated multi-omics profiling identified STT3A (oligosaccharyltransferase) and ALG5 (dolichyl-phosphate β-glucosyltransferase) as key regulators of age-related HC adaptation, with their upregulation in aged macaque hippocampi driving N-glycosylation-dependent metabolic reprogramming.

A new deep learning model for predicting IMRT dose distributions for lung cancer with dose masks.

Purpose: 3D U-Net deep neural networks are widely used for predicting radiotherapy dose distributions. However, dose prediction for lung cancer IMRT is limited to conventional radiotherapy, with significant errors in predicting the intermediate and low-dose regions.

Methods: We included a mixed dataset of conventional radiotherapy and simultaneous integrated boost (SIB) radiotherapy with various prescription schemes.

Long-Term In Situ Treatment of Arthritis with Injectable Biocompatible Organogel Activation.

Rheumatoid arthritis (RA), an autoimmune disease, severely impairs joint function and mobility, causing pain, stiffness, and joint deformity. As an active ingredient of ancient herbs and a widely studied polyphenol flavonoid glycoside, quercetin has a historical use in the treatment of rheumatoid arthritis. However, its low oral bioavailability and potential carcinogenic effects limit its systemic use.

Monolayer MnPS Nanosheet Integration for Extended Exciton Diffusion and Charge Transport in High-Performance Thickness-Insensitive Organic Photovoltaics.

Industrial-scale roll-to-roll processing of organic photovoltaics (OPVs) requires photoactive layers ≥300 nm for manufacturability and mechanical robustness, yet state-of-the-art high-efficiency systems remain confined to 80-120 nm due to intrinsic exciton diffusion and charge transport limitations. To resolve this fundamental thickness-efficiency trade-off, monolayer MnPS nanosheet (1-2 nm) via liquid-phase exfoliation are engineered to extend exciton diffusion lengths and out-of-plane charge mobility, as validated through multimodal characterization. The optimized PM6:Y6:MnPS system achieves record efficiencies of 19.

Oligonucleotide-immobilized PEGylated black phosphorene with enhanced stability and activity for electrochemical detection of trace uranyl.

The development of efficient, sensitive and rapid uranyl ion (UO) detection technology plays a critical role in promoting the utilization of uranium resources and protecting the environment. In this study, a novel composite of BP-mPEG-Olig was synthesized by immobilizing oligonucleotides (Oligs) on black phosphorene (BP), using maleimide-polyethylene glycol (mPEG) as both the linker and passivator. BP-mPEG-Olig utilizes the excellent electrical conductivity and high specific surface area of BP and the high affinity and molecular recognition capability of Oligs for electrochemical UO sensing.

Direct liquefying organic cages into porous liquid molecules for enhanced near-infrared photothermal conversion and catalysis.

The direct liquefaction of molecular cages by incorporating alkyl chains as sterically hindered fluids, without compromising porosity due to self-filling, presents a significant challenge. Here, we demonstrate that transforming hydrophobic amine cages into hydrophilic ammonium cages via quaternization with poly(ethylene glycol) bearing a terminal carboxylic acid produces a series of targeted type I porous liquid molecules featuring a porous ammonium cage as the cation and multiple carboxylate ions as anions on a kilogram scale. The hydrophobic-hydrophilic incompatibility between the cation and anion prevents alkyl chain interpenetration, preserving porosity and liquidity.

Reconfigurable photothermal doping filament for selective spin manipulation and addressing.

The room temperature manipulation of solid-state spins provides an opportunity to develop quantum applications under ambient conditions. Local electromagnetic fields, that usually produced by current in micro/nanoscale metal wires, have been employed for the coherent driving and addressing of spin qubit. However, the fixed distribution limits the spatial selectivity and efficiency of qubit manipulation, which is of central importance in a scaled-up quantum system.

Adsorptive Removal Behavior of Two Activated Carbons for Bis(2-ethylhexyl) Phosphate Dissolved in Water.

Bis(2-ethylhexyl) phosphate (P204) is widely used in extraction processes in the nuclear and rare earth industries. However, its high solubility in water results in high levels of total organic carbon and phosphorus in aqueous environments, and may also lead to radioactive contamination when it is used to combine with radionuclides. In this paper, we characterized a coconut shell activated carbon (CSAC) and a coal-based activated carbon (CBAC) for the adsorption of P204 and then evaluated their adsorption performance through batch and column experiments.

Robust copper-based cationic metal-organic frameworks for efficient sequestration of perrhenate/pertechnetate.

Recent studies have extensively reported the use of cationic metal-organic frameworks (MOFs) for capturing perrhenate/pertechnetate (ReO/TcO) from waste water. Despite the high sorption efficiency of some materials, their stability in strongly acidic and alkaline environments remains inadequate, which hinders their further application in nuclear waste post-processing. Herein, we constructed two different copper-based cationic metal-organic frameworks (ZJU-X16 and ZJU-X17) with excellent resistance to strong acids and alkalis.

Feasibility study of LYSO-SiPM in-beam TOF-PET for dose monitoring in carbon-ion radiotherapy.

In-beam positron emission tomography (PET) is a promising approach for dose monitoring in carbon-ion radiotherapy (CIRT). This study evaluated the feasibility of a dual-head PET system using lutetium-yttrium oxyorthosilicate (LYSO) scintillators and silicon photomultiplier (SiPM) detectors incorporating time-of-flight (TOF) technology to monitor carbon-ion beam dose distribution.The dual-head PET system includes four modules per head, each comprising a 12 × 12 array of LYSO crystals (4.

Integrated approach to predicting rock fracture intensity based on radon tracing and artificial neural network.

In geological and engineering practices, determining fracture intensity of rock masses is critical for the exploitation of resources such as oil, natural gas, uranium, and geothermal energy. Due to the lack of technological means to directly measure the distribution of rock fractures, it is very difficult to obtain the rock fracture intensity. This paper proposes an integrated approach to predicting rock fracture intensity based on artificial neural network (ANN) and radon tracing.

Fabrication of wide angle polarized 3He cells in China Spallation Neutron Source (CSNS).

As part of ongoing upgrade efforts in the China Spallation Neutron Source (CSNS), the neutron polarization team has been actively working on the fabrication procedure of 3He-based neutron spin filters having large angle coverage. We report substantial success in blowing and filling the first wide-angle 3He glass cells in China. The contained 3He gas is polarized on our off-situ spin-exchange optical pumping system.

Topology-Templated Synthesis of Dibenzo[g,p]Chrysene-Based sp Carbon-Linked Covalent Organic Frameworks with Kagome Lattice for Enhanced Photocatalytic Hydrogen Evolution.

Two-dimensional covalent organic frameworks (2D-COFs) have emerged as prominent photocatalysts for photocatalytic hydrogen evolution. However, the exquisite design of linkage and topological structures is crucial for efficient charge generation, separation, and transfer in the planar periodic framework. Here, an imine-linked dibenzo[g,p]chrysene-based COF (DBC-Imine-COF) is presented as a template for topology-templated synthesis of two 2D sp carbon-linked COFs (dibenzo[g,p]chrysene-based DBC-spc-COF and tetraphenylethylene-based TPE-spc-COF) with Kagome lattice to boost photocatalytic hydrogen evolution.

Identifying NPP operator stressors using grounded theory.

Nuclear power plant (NPP) operators manage crucial decision-making and operational tasks in precarious and complex environments, where psychological stress directly correlates with system safety and operational efficiency. However, the existing research largely explores single factors or specific scenarios, lacking systematic analysis. This study aims to identify psychological stress-influencing factors for nuclear power plant operators based on grounded theory.

The n-γ discrimination method for over-range waveforms in digitizer.

This paper aims to address the issue of neutron-gamma discrimination in over-range waveforms by proposing an innovative method based on Pulse Shape Discrimination (PSD) technology. Utilizing a DT5751 digitizer and an EJ-301 detector, signal waveforms from aCf neutron source were acquired and analyzed. The study delves into the specific impact of the over-range waveforms on the PSD spectrum and the resulting n-γ discrimination challenges.

An activatable polymeric nano-spy for reversing the progression of diabetic osteoporosis.

Diabetic osteoporosis (DOP), a grievous complication of diabetes mellitus, is marked by accelerated bone loss and heightened fracture susceptibility, thereby necessitating early detection and therapeutic intervention. To address this unmet clinical need, we herein report a polymeric nano-spy (RAFP NP) that can activate its near-infrared (NIR) fluorescence and release therapeutic drug in response to specific early-stage stimuli within the DOP environment for the diagnosis and treatment of DOP. RAFP NPs are self-assembled from an integrin-targeted and reactive oxygen species (ROS)-responsive amphiphilic copolymer (PLGA-TK-cRGD) that encapsulates the near-infrared fluorochrome Cy5 and the anti-ferroptosis drug Fer-1.

Colloid mediated transport of Uranium(IV) in sulfide-rich aquifers: An overlooked pathway for uranium remobilization under the reductive conditions.

Immobilization of uranium via reductive precipitation is considered for remediation of uranium contaminated groundwater, however, the potential risk deriving from the migration of colloidal-state uranium challenges the remediation effectiveness. In this work, interaction and cotransport of uranium with bentonite colloids (BC) and humic acid (HA) were investigated under reductive conditions through sets of pyrite doped quartz sand columns. Uranium showed considerable mobility as the tetravalent state in the reductive media, both BC and HA significantly affected the transport of uranium, which were regulated by hydrochemical conditions.

High Spatial Resolution Perovskite Fast Neutron Imaging Screen by Cl (n, p) Nuclear Reaction.

Fast neutron imaging has emerged as a highly adaptable non-destructive inspection tool in industrial applications and scientific research. This technique predominantly employs hydrogen-rich scintillation screens based on the principle of nuclear recoil; however, it suffers from limited spatial resolution due to significant energy diffusion of recoil protons. Herein, a 1D perovskite, CsCuClI is demonstrated, for fast neutron imaging based on Cl (n,p) nuclear reaction.

Attention-Guided Residual Spatiotemporal Network with Label Regularization for Fault Diagnosis with Small Samples.

Fault diagnosis is of great significance for the maintenance of rotating machinery. Deep learning is an intelligent diagnostic technique that is receiving increasing attention. To address the issues of industrial data with small samples and varying working conditions, a residual convolutional neural network based on the attention mechanism is put forward for the fault diagnosis of rotating machinery.

Specific recognition schemes based on structure-activity relationship: Aniline-functionalized carbon dots for the detection of pyrethroids in beef and environment.

Herein, an innovative approach was proposed for detecting pyrethroids, which pose potential health risks due to their long accumulation in environmental media. To solve their on-site rapid detection, a fluorescence sensor was developed based on aniline-functionalized carbon dots (CDs) specifically designed to detect 3-phenoxybenzaldehyde (3-PBD), one of the primary metabolites resulting from the hydrolysis of pyrethroids. Through screening 13 substituted anilines, 2-chloro-1,4-phenylenediamine (CPDA) was confirmed to have the highest quenching efficiency.

Boron-Containing Nanoenzyme for Effective Treatment of Melanoma through Boron Neutron Capture Therapy Combined with Catalytic Therapy.

Boron neutron capture therapy (BNCT) is a re-emerging field to achieve precision treatment of malignant tumors with its unique biotargeting and heavy-ion effects, and combination therapy could effectively improve the therapeutic efficacy of BNCT. Herein, a tumor-targeted boron-containing nanozyme was prepared to achieve the combination of BNCT and catalytic therapy for the effective treatment of melanoma. Notably, the boron-containing nanoenzyme exhibited strong peroxidase-like catalytic activity, had skin melanoma cell selectivity, and could undergo a catalytic reaction within the tumor cells to induce apoptosis.

Glymphatic activity in behavioral variant frontotemporal dementia: Link with vascular function and astrocytic activation.

Introduction: Glymphatic activity, vascular function, and astrocytic activation play pivotal roles in the pathophysiology of frontotemporal dementia (FTD). However, their interrelationships and combined impact on clinical features remain unclear.

Methods: Glymphatic activity was measured by diffusion tensor image analysis along the perivascular space (DTI-ALPS) in patients with behavioral variant FTD (bvFTD, n = 61) and normal controls (NC, n = 61).

Speciation analysis of I in spent nuclear fuel solutions.

The lack of a suitable method for the speciation analysis of iodine-129 (I) in spent nuclear fuel solutions has hindered both comprehensive understand and precise control of I prior to plutonium and uranium separation in reprocessing nuclear fuel. In this work, a sequential separation procedure is established to quantify multiple I species in spent nuclear fuel solutions, namely I, IO, and colloidal PdI and AgI, based on their distinct physicochemical properties. I was initially transferred into an upper mesitylene phase via N sparging from an acidic spent nuclear fuel solution.