Identifying NPP operator stressors using grounded theory.

Nuclear power plant (NPP) operators manage crucial decision-making and operational tasks in precarious and complex environments, where psychological stress directly correlates with system safety and operational efficiency. However, the existing research largely explores single factors or specific scenarios, lacking systematic analysis. This study aims to identify psychological stress-influencing factors for nuclear power plant operators based on grounded theory.

The effects of robot anthropomorphic characteristics on employees' anti-robot sabotage.

Robot anthropomorphic characteristics have not only been widely manifested in production practices, but their positive effects on human-robot interaction have also been investigated and validated in academic research. Nonetheless, existing research has not adequately addressed the potential adverse effects of robot anthropomorphic characteristics. To gain a more comprehensive understanding of their influence, this study introduces a dual-edged sword effect model based on cognitive-experiential self-theory.

Light-Addressable Regenerative Photoelectrochemical Biosensor Array with Self-Calibration for High-Throughput and Accurate Detection of Circulating Tumor Cells.

High-efficiency detection of circulating tumor cells (CTCs) provides real-time information for cancer diagnosis and therapy. The light-addressable photoelectrochemical biosensor array (LAPECBA) is the best candidate for rapid and high-throughput detection. However, strong background interference, baseline drift, and batch deviation hinder the further application of LAPECBA.

Recent advances for core-shell gallium-based liquid metal particles: properties, fabrication, modification, and applications.

Gallium-based liquid metal micro-nanoparticles (Ga-LMPs) have attracted extensive attention in recent years due to their unique physicochemical properties, such as biocompatibility, fluidity and large specific surface area. However, the surface of gallium-based liquid metal is prone to oxidation, forming a solid insulating gallium oxide shell that limits its functionality and applications. Therefore, it has become a hot research topic to endow Ga-LMPs with new functionalities by surface modification.

Tri-network PVA/chitosan/gelatin hydrogel modified by tannic acid with self-healing, adhesive and anti-inflammatory properties to accelerate wound healing.

Wound inflammation is a key issue in wound healing as it often causes serious complications and delays wound healing. In this study, hemostatic and antimicrobial hydrogels composed of polyvinyl alcohol (PVA), chitosan (CS) and gelatin (Gel) were prepared. Phenylboronic acid (3-CPBA) and tannic acid (TA) were introduced to modify the multinetwork hydrogel to promote wound repair.

Flexible Solar-Blind Ultraviolet Photodetector Based on β-GaO Nanowire Channel Bridge Structure: Combining High Responsivity and Strain Stability.

Solar-blind ultraviolet photodetectors are gaining attention for their high signal-to-noise ratio and strong anti-interference capabilities. With the rising demand for applications in high-strain environments, such as fire rescue robots and smart firefighting suits, a flexible photodetector that maintains stable performance under bending strain is needed. Current devices struggle to balance strain cycle stability and responsivity.

Photoelectrochemical and fluorescent dual-mode sensitive detection of circulating tumor cells based on aptamer DNA-linked CdTe QDs/BiMoO/CdS "double Z-scheme" system.

Herein, a novel dual-mode biosensor integrating photoelectrochemical (PEC) and fluorescence (FL) sensing detection was developed for circulating tumor cells (CTCs) based on aptamer DNA-linked CdTe QDs (Apt-CdTe QDs)/BiMoO/CdS "dual Z-scheme" sensing system. Apt-CdTe QDs were assembled on FTO/CdS/BiMoO/cDNA electrode through hybridization with cDNA, resulting in the formation of a double Z-scheme CdS/BiMoO/CdTe heterostructure that significantly enhanced the separation of photo-generated charge carriers, thereby improving photocatalytic efficiency. Upon the presence of MCF-7 cells, Apt-QDs were captured and subsequently released from the captured electrode, leading to a decrease in photocurrent and an increase in fluorescence intensity, thus enabling effective PEC-FL dual-mode detection.

Recognition and localization of ratoon rice rolled stubble rows based on monocular vision and model fusion.

Introduction: Ratoon rice, as a high-efficiency rice cultivation mode, is widely applied around the world. Mechanical righting of rolled rice stubble can significantly improve yield in regeneration season, but lack of automation has become an important factor restricting its further promotion.

Methods: In order to realize automatic navigation of the righting machine, a method of fusing an instance segmentation model and a monocular depth prediction model was used to realize monocular localization of the rolled rice stubble rows in this study.

MXene Hollow Microsphere-Boosted Nanocomposite Electrodes for Thermocells with Enhanced Thermal Energy Harvesting Capability.

Thermal energy, constantly being produced in natural and industrial processes, constitutes a significant portion of energy lost through various inefficiencies. Employing the thermogalvanic effect, thermocells (TECs) can directly convert thermal energy into electricity, representing a promising energy-conversion technology for efficient, low-grade heat harvesting. However, the use of high-cost platinum electrodes in TECs has severely limited their widespread adoption, highlighting the need for more cost-effective alternatives that maintain comparable thermoelectrochemical performance.

An Entropy-Driven Multipedal DNA Walker Microsensor for In Situ Electrochemical Detection of ATP.

Microelectrode- and nanoelectrode-based electrochemistry has become a powerful tool for the in situ monitoring of various biomolecules in vivo. However, two challenges limit the application of micro- and nanoelectrodes: the difficulty of highly sensitive detection of nonelectroactive molecules and the specific detection of target molecules in complex biological environments. Herein, we propose an electrochemical microsensor based on an entropy-driven multipedal DNA walker for the highly sensitive and selective detection of ATP.

A stable zeolite with atomically ordered and interconnected mesopore channel.

Zeolites are crystalline microporous materials constructed by corner-sharing tetrahedra (SiO and AlO), with many industrial applications as ion exchangers, adsorbents and heterogeneous catalysts. However, the presence of micropores impedes the use of zeolites in areas dealing with bulky substrates. Introducing extrinsic mesopores, that is, intercrystal/intracrystal mesopores, in zeolites is a solution to overcome the diffusion barrier.

Construction of a Bifunctional Nanoelectrode for Intracellular Natural Product Delivery and Monitoring Anticancer Efficiency in Single Cells.

Natural products play a significant role in new drug discovery and anticancer therapy, making the evaluation of their anticancer efficiency crucial for clinical application. However, delivering natural products to single cells and in situ monitoring of induced signaling molecule fluctuation to evaluate anticancer efficiency remain significant challenges. Hence, we proposed a universal and straightforward strategy to construct a bifunctional nanoelectrode that integrates drug loading and monitoring of signal molecule fluctuations at the single-cell level.

Surprising diversity of new plasmids in bacteria isolated from hemorrhoid patients.

Background: Hemorrhoids are common conditions at or around the anus, to which numerous people suffer worldwide. Previous research has suggested that microbes may play a role in the development of hemorrhoids, and the origins of these microbes have been preliminarily investigated. However, no detailed research on the microbes related to hemorrhoid patients has been conducted.

Design, synthesis and biological evaluation of thieno[3,2-c]pyrazol-urea derivatives as potent glycogen synthase kinase 3β inhibitors based on the DFG-out conformation.

Glycogen synthase kinase 3β (GSK-3β) is a potential therapeutic target for the treatment of a variety of human diseases. Here, we report the design and synthesis of a series of thieno[3,2-c]pyrazol-urea derivatives and evaluation of their GSK-3β inhibitory activity. Among these analogues, the compound without substitution on terminal phenyl ring (3a) was found to be the most potent GSK-3β inhibitor with an IC of 74.

Robust, Efficient, and Recoverable Thermocells with Zwitterion-Boosted Hydrogel Electrolytes for Energy-Autonomous and Wearable Sensing.

The rapid growth of flexible quasi-solid-state thermocells (TECs) provides a fresh way forward for wearable electronics. However, their insufficient mechanical strength and power output still hinder their further applications. This work demonstrates a one-stone-two-birds strategy to synergistically enhance the mechanical and thermoelectrochemical properties of the [Fe(CN)]-based TECs.

A photoelectrochemical cytosensor based on a BiS-MoS heterojunction-modified reduced oxide graphene honeycomb film for sensitive detection of circulating tumor cells.

A novel photoelectrochemical (PEC) cytosensor for the ultrasensitive detection of circulating tumor cells (CTCs) was developed. The bio-inspired reduced graphene oxide (rGO) honeycomb film photoelectrode was fabricated a "breath figure" method, followed by the self-assembly of a BiS-MoS heterojunction. The resulting BiS-MoS heterojunction-modified rGO honeycomb film was employed as a sensing matrix for the first time.

Tumor selective self-assembled nanomicelles of carbohydrate-epothilone B conjugate for targeted chemotherapy.

Epothilone B (Epo B) is a potent antitumor natural product with sub-nanomolar anti-proliferation action against several human cancer cells. However, poor selectivity to tumor cells and unacceptable therapeutic windows of Epo B and its analogs are the major obstacles to their development into clinical drugs. Herein, we present self-assembled nanomicelles based on an amphiphilic carbohydrate-Epo B conjugate that is inactive until converted to active Epo B within the tumor.

Synthesis and anti-SARS-CoV-2 evaluation of lipid prodrugs of β-D-N-hydroxycytidine (NHC) and a 3'-fluoro-substituted analogue of NHC.

β-D-N-hydroxycytidine (NHC, EIDD-1931) is a nucleoside analogue that exhibits broad spectrum antiviral activity against a variety of RNA viruses. Herein, we report the synthesis of a series of lipid prodrugs of NHC and a novel 3'-fluoro modified NHC analogue, and evaluation of their antiviral activity against five variants of SARS-CoV-2. All lipid prodrugs showed potent antiviral activity against the tested SARS-CoV-2 variants with EC values in the range of 0.

My Family Accounts Much for Me: How Does Work-to-Family Conflict Lead to Unethical Pro-Family Behavior.

Although unethical behaviors are prevalent in the workplace, little is known about the unethical behavior aiming at benefiting one's family (unethical pro-family behavior, UPFB). In this paper, we leverage self-determination theory to explore the association between work-to-family conflict and UPFB. Specifically, we hypothesize and corroborate a positive relationship between work-to-family conflict and UPFB, and such relationship is mediated by family motivation.

Capture and release of circulating tumor cells stimulated by pH and NIR irradiation of magnetic FeO@ZIF-8 nanoparticles.

Detecting and analyzing circulating tumor cells(CTCs) is significant for early diagnosis, management, and personalized treatment of tumors. Herein, a smart magnetic aptamer modified FeO@ZIF-8 core/shell structured nanoparticle (NPs) was successfully constructed using for capture and simultaneous pH- and NIR-irradiation responsive release of CTCs. Taking MCF-7 as model CTCs, it could be captured ca.

The Identification of APOBEC3G as a Potential Prognostic Biomarker in Acute Myeloid Leukemia and a Possible Drug Target for Crotonoside.

The apolipoprotein B mRNA editing enzyme catalytic subunit 3G (APOBEC3G) converts cytosine to uracil in DNA/RNA. Its role in resisting viral invasion has been well documented. However, its expression pattern and potential function in AML remain unclear.

Highly Selective Carbonylation of CH Cl to Acetic Acid Catalyzed by Pyridine-Treated MOR Zeolite.

The selective conversion of methane to high value-added chemicals under mild conditions is of great significance for the commercially viable and sustainable utilization of methane but remains a formidable challenge. Herein, we report a strategy for efficiently converting methane to acetic acid via CH Cl as an intermediate. Up to 99.