OccScene: Semantic Occupancy-based Cross-task Mutual Learning for 3D Scene Generation.

Recent diffusion models have demonstrated remarkable performance in both 3D scene generation and perception tasks. Nevertheless, existing methods typically separate these two processes, acting as a data augmenter to generate synthetic data for downstream perception tasks. In this work, we propose OccScene, a novel mutual learning paradigm that integrates fine-grained 3D perception and high-quality generation in a unified framework, achieving a cross-task win-win effect.

A Perspective on High-Entropy Oxides as Potential Electromagnetic Wave Absorbers.

The escalating impact of electromagnetic radiation on human health and electronic device stability has driven intensive research into advanced electromagnetic wave absorption (EMA) materials in recent decades. Among them, high-entropy oxides (HEOs) have evolved into increasingly popular research in the material field since they were first reported in 2015. They are particularly promising for EMA applications due to their remarkable tunability and almost infinite compositional flexibility.

Vapor-phase fluorination to regulating oxygen content of silicon anode materials.

SiO is a high-potential candidate material for silicon (Si) derived anodes, owing to its high specific capacity and commendable cycling performance. However, the irreversible formation of phases during lithiation results in low Initial Coulombic Efficiency (ICE). In this work, the Si/C composite (Si@FC) with a fluorine (F) -doped bilayer structure is synthesized via "Vapor-Phase Fluorination" using Polytetrafluoroethylene (PTFE) as a source of fluorine and carbon.

Precisely tuning band gaps of graphene/h-BN lateral heterostructures toward enhanced photocatalytic hydrogen evolution.

Constructing heterojunctions is a proven strategy for developing efficient photocatalytic hydrogen evolution catalysts. In this work, we design graphene/hexagonal boron nitride (h-BN) lateral heterostructures that combine graphene's exceptional charge transport with h-BN's stability. Using state-of-the-art many-body green's function theory (MBGFT) simulations, we establish a band engineering framework through dimensional control, demonstrating that precise modulation of graphene and h-BN domain sizes enables continuous visible-spectrum band gap tuning for efficient hydrogen generation.

A novel GPR84 antagonist attenuates diabetic lung injury by inhibiting pyroptosis via the cGAS-STING pathway in pulmonary vascular endothelial cells.

Diabetic lung injury (DLI) is a severe complication of diabetes, characterized by pulmonary vascular endothelial cell damage, inflammation, and pyroptosis. However, the underlying molecular mechanisms remain unclear. This study investigates the role of G-protein-coupled receptor 84 (GPR84) in DLI and its regulation of pyroptosis via the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway.

Screening, Identification, and Whole-Genome Sequencing of Ferulic Acid Esterase-Producing Lactic Acid Bacteria from Sheep Rumen.

Ferulic acid esterase (FAE) plays an important role in plant fiber degradation by catalyzing the hydrolysis of lignocellulosic structures. FAE-producing lactic acid bacteria (LAB), as potential probiotics, can improve ruminant digestion and gut health. In this study, two LAB strains (Q2 and Q6) with FAE activity were isolated from sheep rumen.

NNMT-mediated N-methyladenosine modification of NR4A3 mRNA facilitates lymphatic metastasis of gastric adenocarcinoma.

Lymph node (LN) metastasis is a common feature of gastric adenocarcinoma (GAC) and is closely associated with a poor prognosis. Our previous study highlighted the pivotal role of nicotinamide N-methyltransferase (NNMT) in driving GAC carcinogenesis and malignant progression, primarily through its regulation of histone methylation. However, the mechanisms by which NNMT contributes to LN metastasis in GAC remain poorly understood.

Stress hyperglycemia ratio and the risk of new-onset chronic diseases: results of a national prospective longitudinal study.

Background: The stress hyperglycemia ratio (SHR), a dynamic biomarker of acute glucose dysregulation, has been established as a predictor of adverse acute outcomes. However, its longitudinal associations with chronic disease development, particularly in middle-aged and older populations, remain insufficiently characterized.

Methods: This nationwide prospective cohort study analyzed data from 8942 adults aged ≥ 45 years in the China Health and Retirement Longitudinal Study (CHARLS).

Latent profile analysis and influencing factors of psychological resilience in parents of children with autism.

Objective: Based on Kumpfer's psychological resilience framework, this study aimed to explore the potential categories of psychological resilience among parents of autistic children and to analyze the influencing factors of these categories.

Methods: Data were collected using a general information questionnaire, the Connor-Davidson Resilience Scale (CD-RISC), the Multidimensional Scale of Perceived Social Support (MSPSS), the General Self-Efficacy Scale (GSES), and the Simple Coping Style Questionnaire (SCSQ). From October 2023 to October 2024, a survey was conducted with 350 parents of autistic children at rehabilitation departments and hospitals in western Liaoning Province.

USP4-mediated deubiquitination of SRC-1 regulates macrophage polarization and asthma inflammation.

Asthma, the most common chronic respiratory disorder affecting individuals of all ages, is driven by inflammation that leads to airway hyperresponsiveness, airway wall remodeling, and mucus production. While inhaled corticosteroids remain the primary treatment despite their limitations, further research into the molecular mechanisms of asthma is needed to identify new therapeutic targets. A mouse model of asthma was created by treating mice with OVA.

When Cultural Resources Amplify Psychological Strain: Off-Work Music Listening, Homophily, and the Homesickness-Burnout Link Among Migrant Workers.

Hundreds of millions of migrants experience frequent homesickness that affects their psychological wellbeing. This study integrates the job-demands-resources model and temporal comparison theory to examine how music listening and similar activities involving coworker homophily and roommate homophily influence the relationship between homesickness and burnout. Our analysis of survey data from 2493 migrant workers reveals that off-work music listening strengthens the positive relationship between homesickness and burnout.

Deciphering the preservative effects of protamine from Xinjiang Coregonus peled on grass carp (Ctenopharyngodon idellus) fillets during refrigerated storage: a perspective from the microbiome.

Protamine is a natural cationic peptide which has been utilized as a food preservative, since its antibacterial capability against a wide range of Gram-negative and -positive bacteria. Despite the antibacterial mechanism has been well uncovered, its role in complex food microbial communities is largely elusive. In the present study, grass carp (Ctenopharyngodon idellus) fillets were treated with protamine and a protamine-based compound preservative, and stored at 4 °C for 15 days.

Self-Similar Superhydrophobic Whisker-Based Coatings with High Impact and Abrasion Resistance.

Spray-on fabrication of superhydrophobic (SH) coatings using nanoparticles (NPs) has broad applications, but their mechanical durability often falls short of practical requirements. In this work, we demonstrate that mixing NPs with well-dispersed SiC whiskers (SiCw) can significantly improve the SH stability and mechanical durability of sprayed coatings, even under complex and harsh impact/abrasion conditions (such as sandblasting), which is attributed to the formation of a fully connected, avian nest-like, self-similar SiCw framework via the random packing of whiskers during coating drying. The resulting coating exhibits exceptional abrasion resistance, enduring 1,000 dry and 900 wet cycles in Taber abrasion tests (CS-17 wheels), and shows negligible degradation after impact testing at 3.

Development and validation of a CT-based radiomics nomogram for predicting progression-free survival in patients with small cell lung cancer.

Purpose: Small cell lung cancer (SCLC) is a highly aggressive form of lung cancer, representing about 15% of cases worldwide. Despite advances in imaging, such as low-dose CT, which have increased diagnostic rates, survival outcomes for SCLC patients have remained stagnant. Recent studies have only focused on radiomics, which extracts detailed quantitative features from imaging, with clinical risk factors to improve prognostic models.

Interaction of nutritional and inflammatory levels on all-cause mortality among individuals with rheumatoid arthritis: a prospective cohort study.

Background: Malnutrition and systemic inflammation are frequently prevalent in individuals with rheumatoid arthritis (RA). However, limited studies have explored the combined impacts of nutritional and inflammatory levels on all-cause mortality among RA. This study is aimed at investigating these potential associations.

Neutrophil percentage-to-albumin ratio and the risk of all-cause and cardiovascular mortality: a 20-year follow-up cohort study of 36,428 US adults.

Background: The neutrophil percentage-to-albumin ratio (NPAR) has been identified as a prognostic indicator of mortality in various diseases; however, its association with all-cause and cardiovascular mortality in the general population remains insufficiently studied.

Methods: This retrospective cohort study analyzed data from 36,428 individuals who participated in the National Health and Nutrition Examination Survey between 1999 and 2018. Participants were divided into tertiles based on NPAR levels, with follow-up data collected through December 31, 2019.

MVP-LCN2 axis triggers evasion of ferroptosis to drive hepatocarcinogenesis and sorafenib resistance.

RNA-binding proteins (RBPs) are critical regulators in tumorigenesis and therapy resistance by modulating RNA metabolism. However, the role of RBPs in hepatocarcinogenesis and progression remains elusive. Here, RBPs screening and integrating analyses identify major vault protein (MVP) as an oncogenic RBP in the occurrence of hepatocellular carcinoma (HCC) and sorafenib resistance via suppressing ferroptosis.

Berberine improves cardiac insufficiency through AMPK/PGC-1α signaling-mediated mitochondrial homeostasis and apoptosis in HFpEF mice.

Background: Heart failure (HF) with preserved ejection fraction (HFpEF) accounts for approximately half of cases of HF and is frequently clinically underdiagnosed. Although new therapies continue to emerge, determining optimal treatment strategies persists as a key clinical dilemma. Berberine(BBR), an isoquinoline alkaloid, is known to attenuate HF with reduced ejection fraction.

Synthesis of aromatic amides from lignin and its derivatives.

Benzamides constitute an important class of bulk and fine chemicals as well as essential parts of many life science molecules. Currently, all these compounds are majorly produced from petrochemical-based feedstocks. Notably the selective aerobic oxidative conversion of lignin and lignin-derived compounds to primary, secondary, and tertiary amides and phenols offers the potential for a more sustainable synthesis of valuable building blocks for fine chemicals, monomers for polymers, biologically active molecules, and diverse consumer products.

The addition of alpha-ketoglutarate to NT-proBNP improves the prediction of long-term all-cause mortality in acute heart failure patients.

Background And Objective: Alpha-ketoglutarate (AKG), is a major intermediate metabolite of the tricarboxylic acid cycle, and is closely associated with cardiometabolic disease prognosis. Previous studies indicated that AKG is related to myocardial energy expenditure levels and reflects adverse short-term outcomes in heart failure (HF) patients. In this prospective cohort study, we examined the long-term prognostic value of AKG levels in acute HF (AHF) patients.

Multiferroicity in two-dimensional III-V indium pnictide optoelectronic materials.

Three-dimensional (3D) III-V semiconductors including indium pnictides are widely used in optoelectronic devices, such as light-emitting diodes, laser diodes and photodetectors, in their bulk or thin-film geometries. On the other hand, two-dimensional (2D) atomic crystals such as graphene, phosphorene, and transition metal dichalcogenides are promising candidates for next generation optoelectronic technologies. Here, we designed a type of III-V indium pnictide 2D material that can be exfoliated and rebuilt from bulk wurtzite structures, which show benign stability and intriguing physical properties, including in-plane ferroelectricity/antiferroelectricity with low transition barriers (0.

Associations of the C-reactive protein-albumin-lymphocyte index with all-cause and cardiovascular mortality among individuals with cardiovascular disease: evidence from the NHANES 2001-2010.

Background: Evidence regarding the C-reactive protein‒albumin‒lymphocyte (CALLY) index and mortality risk in individuals with cardiovascular disease (CVD) is scarce. This study investigated the relationships of the CALLY index with all-cause and cardiovascular mortality risk in CVD patients among American adults.

Methods: This study enrolled 2183 CVD individuals from five NHANES cycles (2001-2010), and mortality outcomes were determined by linking the data to National Death Index (NDI) records up to December 31, 2019.

Self-sacrificing template-derived N/O-doped porous carbons: Exceptional capacitor performance across environmental extremes.

Heteroatom-doped porous carbon exhibit promising potential as supercapacitor electrodes, but the tradeoff between specific surface area (SSA) and heteroatom-doped level limits its excellent performance. In this work, the activation coupled with doping strategy to synthesize the pitch-based porous carbon (PPC). Different from single activation method to prepare microporous carbon, the PPC prepared by the coupling method has a hierarchical porous structure and high SSA (2020 m/g).

NAT10 Promotes Gastric Cancer Liver Metastasis by Modulation of M2 Macrophage Polarization and Metastatic Tumor Cell Hepatic Adhesion.

The relationship between patterns of RNA modifications and gastric cancer (GC) liver metastasis (GCLM) remains unclear. Here, by single-cell sequencing, clinical sample analysis, and mouse model studies, an abnormal increase in the expression of the RNA acetyltransferase N-acetyltransferase 10 (NAT10) in liver metastatic GC cells is identified. NAT10-mediated N4-acetylcytidine modification of CXCL2 and KLF5 mRNA increases their stability.

Association between the C-reactive protein-albumin-lymphocyte index and metabolic syndrome: evidence from the 2003-2010 national health and nutrition examination survey.

Background: Metabolic syndrome (MetS) is a global public health problem that significantly impacts human health and quality of life. The relationship between MetS and the C-reactive protein-albumin-lymphocyte (CALLY) index is uncertain.

Methods: This study analyzed the data of 7,534 individuals from the National Health and Nutrition Examination Survey cycles (2003-2010 cycles).