[Occurrence Characteristics of Microplastics and Influencing Factors in Coastal Salinized Soil].

Microplastics are widespread in terrestrial and marine environments. As a transition zone between land and ocean, coastal soils have unique microplastic pollution characteristics. To reveal the characteristics of microplastic pollution in coastal soils, soils with different salinization levels were collected from Wudi County toward the sea.

NRT1.1B acts as an abscisic acid receptor in integrating compound environmental cues for plants.

Abscisic acid (ABA) is the most crucial phytohormone for plants in adapting to environmental conditions. While the ABA signaling network in plants has been extensively explored, our understanding of the diverse ABA sensing systems remains limited. Here, we found that the transcriptional response to ABA is suppressed under high-nitrate conditions but substantially increases under low-nitrate conditions, suggesting a tight integration of ABA signaling with nutrient conditions.

A quantitative analysis of bone defects in displaced proximal humeral fractures using virtual reduction technique.

Background And Objective: Medial column disruption in proximal humeral fractures (PHFs) is associated with poor outcomes following reduction and internal fixation. Current assessments of unstable medial columns rely on qualitative descriptors such as disrupted hinges and insufficient osseous contact, often overlooking the quantification of bone defects. This study aims to quantitatively analyze bone defect characteristics in varus PHFs using advanced computer image processing techniques.

Construction and validation of a frailty risk prediction model for geriatric hematologic neoplasms patients: A cross-sectional study.

BackgroundWith the increasing incidence of malignant hematological neoplasms in the elderly population, debilitating issues have gradually become an important challenge for patients.ObjectivesTo construct a prediction model, draw a nomogram, and perform internal validation of the model.Methods505 elderly patients with hematological neoplasms were included in the study.

Optimized Carbon-Nitrogen Fertilization Boosts Fragrant Rice ( L.) Yield and Quality via Enhanced Photosynthesis, Antioxidant Defense, and Osmoregulation.

The effects of the foliar spraying of carbon and nitrogen on the yield and quality of fragrant rice ( L.) remain unknown. A two-year field experiment was conducted by using two fragrant rice varieties, Meixiangzhan 2 and Xiangyaxiangzhan, as experimental materials.

Salinity decreases the soil organic carbon stock while increasing its stability: A case study in the coastal region of China.

The influence of soil salinity on carbon sequestration is largely unknown, and this is stopping us from being able to accurately evaluate the carbon sequestration capacity of soils with different salinity levels. Fifty-one soil samples were thus collected from Wudi County, China, along a salinity gradient. The density fractionation and Fourier-transform mid-infrared spectroscopy were employed to determine soil organic carbon (SOC) content, constitution and characteristics.

Spatial distribution and seasonal variations of typical UV filter and insect repellent personal care products in a coastal resort area in Qingdao, China.

The occurrence, concentration, spatial distribution, seasonal variations, and ecotoxicological risks of six typical UV filter and insect repellent personal care products (PCPs) were evaluated in multiple environmental matrices (river/estuary/wetland water, seawater, beach sands, local WWTP water and sludges) in a coastal resort area in Qingdao, China. Target PCPs were widely detected, with significantly higher levels in the summer across all matrices. Insect repellents (max = 841.

Heterogeneity and associated factors of information needs among patients with hematological malignancies in China: a latent profile analysis.

Purpose: Hematological malignancies involve complex healthcare situations. Sharing knowledge and providing tailored information based on patients' needs are crucial for patient-centered health care. This study explored information needs among Chinese patients with hematological malignancies and identified factors across distinct subgroups.

Latent profile analysis of fear of progression in Chinese hematologic malignancy survivors.

Fear of disease progression (FoP) is a multidimensional concept that refers to the fear or worry about disease progress. Little is known about the distinct FoP profiles and their determinants in culturally specific contexts, especially among hematologic malignancies (HM) patients in China. This study aimed to identify heterogeneous profiles of FoP and their associated predictors among Chinese patients with HM.

Do weaker solvation effects mean better performance of electrolytes for lithium metal batteries?

The design of novel electrolytes is crucial for ensuring the practical application of high-voltage lithium metal batteries (LMBs). Weakly solvating electrolytes (WSEs), achieved by reducing the solvent's solvation ability, have been shown to improve the cycling stability of LMBs. However, the internal relationship between the weaker solvation effects of the solvent and battery performance is not well understood.

Ultra-low concentration ether electrolytes with strong Coulomb interactions for high-voltage lithium metal batteries.

The advancement of high-energy-density lithium metal batteries (LMBs) necessitates the development of novel electrolytes capable of withstanding high voltages. Ether-based electrolytes, while compatible with lithium metal anodes (LMAs), face limitations in high-voltage stability. Traditional design strategies with high concentration enhance the high-voltage stability of electrolytes by consuming free solvents to prevent their decomposition but face high-cost issues.

Structural Basis for Inhibition of Urate Reabsorption in URAT1.

The urate transporter 1 (URAT1) is the primary urate transporter in the kidney responsible for urate reabsorption and, therefore, is crucial for urate homeostasis. Hyperuricemia causes the common human disease gout and other pathological consequences. Inhibition of urate reabsorption through URAT1 has been shown as a promising strategy in alleviating hyperuricemia, and clinical and preclinical drug candidates targeting URAT1 are emerging.

Heterogeneity in Health-Related Quality of Life of Patients with Aplastic Anemia: A Latent Profile Analysis.

Purpose: Concerns over health-related quality of life (HRQOL) in patients with aplastic anemia (AA) have been increasing worldwide. However, most researches on HRQOL in AA patients have ignored individual-level variability. Thus, our study was designed to explore practical classification of HRQOL and related variables among AA patients.

Straw mineralization and carbon dioxide emissions in soils with different salinity levels.

Straw application is widely used to reclaim saline soils. However, the characteristics of straw mineralization and its induced priming effects (PE) in saline soil are largely unknown. Thus, we conducted a 180-day saline soil incubation experiment to observe the characteristics of straw mineralization and CO emissions.

Effects of polyethylene microplastics on cadmium accumulation in Solanum nigrum L.: A study involving microbial communities and metabolomics profiles.

Combined pollution with heavy metals and microplastics (MPs) is widespread in farmland soil, and MPs can affect the efficiency and capacity of cadmium (Cd) uptake by hyperaccumulators. However, there is a significant knowledge gap regarding the response of hyperaccumulators under such conditions. This study utilized Solanum nigrum L.

Evaluation of sample pooling for gene sequencing of SARS-CoV-2: a simulation study.

Introduction: Coronavirus disease 2019 (COVID-19) continues to pose a significant public health threat, requiring epidemiological and genomic surveillance. Next generation sequencing (NGS) is commonly utilized for monitoring viral evolution at a high cost. This study evaluated pooled sequencing as a cost-effective tool for monitoring virus variants.

BRAF-activated ARSI suppressed EREG-mediated ferroptosis to promote BRAF (mutant) papillary thyroid carcinoma progression and sorafenib resistance.

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, and patients with the BRAF mutation often exhibit aggressive tumor behavior. Here, we identified Arylsulfatase I (ARSI) as a gene whose expression was significantly upregulated in BRAF PTC and was associated with poor prognosis. High ARSI expression correlated with advanced disease stage, BRAF mutation, and worse overall survival in PTC patients.

FBP1 over-expression suppresses HIF-1α in papillary thyroid cancer.

Papillary thyroid carcinoma (PTC) is generally a slow-growing disease with a favorable 10-year survival rate. However, about 10% of PTC cases show significant aggressiveness, with tendencies for local invasion or distant metastasis, the mechanisms of which remain unclear. This study aims to identify predictive indicators and explore new potential targets for clinical treatment, highlighting the need for novel biomarkers and therapeutic targets.

Rapid detection of the SARS-CoV-2 omicron variants based on high-resolution melting curve analysis.

With the continuous spread of the SARS-CoV-2 globally, viral mutations have accumulated. As a result, SARS-CoV-2 became more contagious, and has a higher risk of immune escape and reinfection. To identify variants and have an awareness of the prevalence of these variants, this study selected four segments containing mutations on the S gene of the SARS-CoV-2.

Modeling sarcoplasmic reticulum Ca in rat cardiomyocytes.

The sarcoplasmic reticulum (SR) primarily serves as the intracellular Ca store in cardiac myocytes, mediating cellular function under cardiac physiology and diseases. However, the properties of cardiac SR Ca have not yet been fully determined, particularly in rats and mice, which are the most commonly used experimental species in studies on cardiac physiology and diseases. Here, we developed a spatially detailed numerical model to deduce Ca movements inside the junctional SR (jSR) cisternae of rat cardiomyocytes.

Case report: Germline BRCA 2 mutation in primary peritoneal carcinoma: a rare malignancy.

Background: Primary peritoneal carcinoma (PPC) is a rare malignancy. Clinically, its histological morphology resembles that of epithelial ovarian tumors (EOC), often leading to misdiagnosis. Diagnosis and treatment of PPC are time-sensitive because of the rapidly progressive nature of the disease.

Data-driven approaches linking wastewater and source estimation hazardous waste for environmental management.

Industrial enterprises are major sources of contaminants, making their regulation vital for sustainable development. Tracking contaminant generation at the firm-level is challenging due to enterprise heterogeneity and the lack of a universal estimation method. This study addresses the issue by focusing on hazardous waste (HW), which is difficult to monitor automatically.