Effects of Interspecific Competition on Habitat Shifts of (Temminck et Schlegel, 1846) and (Houttuyn, 1782) in the Northwest Pacific.

As economically important sympatric species in the Northwest Pacific, the Japanese sardine () and Chub mackerel () exhibit significant biological interactions. Understanding the impact of interspecies competition on their habitat dynamics can provide crucial insights for the sustainable development and management of these interconnected species resources. This study utilizes fisheries data of and from the Northwest Pacific, collected from June to November between 2017 and 2020.

Elucidating the gut microbiota-driven crosstalk: mechanistic interplay of lobetyolin in coordinating cholesterol homeostasis and anti-inflammatory pathways in hyperlipidemic mice models.

Background: Hyperlipidemia is a prevalent metabolic disorder closely associated with gut microbiota imbalance. In recent years, traditional Chinese medicine has demonstrated distinct advantages in the regulation of the gut microbiota and enhancement of metabolic health. This study aimed to elucidate the molecular processes by which lobetyolin modifies the gut microbiota to improve intestinal inflammation and lipid metabolism in hyperlipidemic mice.

The Community Structure and Diversity of Heterotrophic Microorganisms in the Soils of Taiga Forests, China.

Heterotrophic microorganisms derive energy by decomposing organic matter. Their composition and community structure are influenced by environmental factors and interactions. Soil heterotrophic respiration was assessed by establishing vegetation removal plots (Hr) and control plots (Sr).

Factors influencing adherence to psychological intervention referrals among women who screened positive for postpartum depression in Shenzhen, China (2016-2020).

Postpartum Depression (PPD) is a significant public health issue in China. Despite the launch of a universal PPD screening and intervention programme in Shenzhen, there remains a substantial gap between the number of women who screened positive and were referred for psychological interventions and those who actually presented at mental health institutions for further evaluation and treatment. This study sought to understand the factors influencing adherence to intervention referrals among women with positive PPD screening results.

Biocontrol of the zearalenone-producer Fusarium ipomoeae on soybean pods using an avirulent Lasiodiplodia theobromae isolate.

Background: Fusarium pod blight is emerging as a destructive disease in soybean-producing regions. Currently, strategies for the management of Fusarium pod blight are lacking. This study aimed to examine the biocontrol activity of a new avirulent Lasiodiplodia theobromae isolate for the management of Fusarium pod blight.

HPVPool-Seq: a genotype-guided pooling strategy for cost-effective next-generation sequencing detection of HPV integration in cervical samples.

Unlabelled: Integration of high-risk human papillomavirus (hrHPV) DNA is a critical event in carcinogenesis and a promising biomarker for risk stratification. However, the high cost of next-generation sequencing (NGS) limits its widespread clinical adoption. We developed HPVPool-Seq, an innovative pooling strategy that leverages the inherent diversity of HPV genotypes as natural barcodes, enabling cost-effective, scalable integration detection.

Influence of eHealth literacy on acceptance of healthcare services with risks in China: chain-mediating effect of general risk propensity and self-efficacy.

Objectives: To investigate factors associated with the acceptance of healthcare services with risks among Chinese public.

Study Design: This national cross-sectional study used data from the 2023 Psychology and Behavior Investigation of Chinese Residents.

Methods: Structural equation modelling was used to analyse the chain-mediated pathways of e-health literacy acting through general risk propensity and self-efficacy on the acceptability of five risky healthcare services (COVID-19 vaccine booster shots, mixed vaccination with COVID-19 vaccine, telemedicine, internet-based home care, and brain-computer interface technology).

Epidemiology, Clinical Features, and Molecular Basis of TTMV::RARA-driven Acute Promyelocytic Leukemia.

Integration of torque teno mini virus (TTMV) generating the TTMV::RARA fusion represents a newly recognized subtype of acute promyelocytic leukemia (APL) that merits detailed investigation. We present the first comprehensive characterization of its epidemiologic profile, clinical presentation, virologic characteristics, and underlying molecular mechanisms. Our findings indicate that TTMV::RARA is more prevalent in pediatric patients and represents the second most common retinoic acid receptor fusion after PML::RARA.

Anatomy-to-Tract Mapping: Inferring White Matter Pathways Without Diffusion Streamline Propagation.

Diffusion tractography, a cornerstone of white matter mapping, relies on point-to-point streamline propagation-a process often compromised by errors stemming from inadequate signal-to-noise ratio and limited spatioangular resolution in diffusion MRI (dMRI) data. Here, we introduce Anatomy-to-Tract Mapping (ATM), the first model to our knowledge that generates bundle-specific streamlines directly from T1-weighted MRI without requiring orientation field estimation, voxelwise segmentation, and streamline propagation. ATM leverages the superior quality and minimal distortion of anatomical MRI and learns from multi-subject datasets to deliver robust, subject-specific streamline bundles with accurate preservation of structural connectivity.

Quantitative microbiome profiling reveals associations between ruminal microbiota shifts and accelerated milk production increase in dairy cows.

Milk is a valuable source of essential nutrients for humans. In dairy cows, the rumen-the largest digestive organ-plays a critical role in supporting high productivity. The postpartum period marks a crucial transition to peak lactation, characterized by a rapid rise in milk and milk solids yield.

Tissue Mild Extraction Enriches Membrane, Cytoplasmic, and Secreted Proteomes for Biomarker Discovery.

Clinical blood biomarkers provide important diagnostic information and are generally secreted, cytoplasmic, membrane, and other soluble proteins. However, in the mass spectrometry-based proteomic biomarker discovery phase, the whole tissue is often lysed directly for analysis, and this increases protein complexity in the sample, limiting the detection of soluble proteins as biomarkers. Here, we use a mild extraction method that includes a low salt buffer and 1% Triton X-100 to isolate proteins from mouse tissues followed by proteomic analyses.

Integration of homologous vanadium oxide and nitride with adjustable interfacial strain and charge for high performance cathode aqueous zinc-ion batteries.

The poor stability and slow kinetics of VO-based electrodes present significant challenges for their implementation in aqueous zinc-ion batteries (ZIBs). Herein, a homologous 2VO-3VN heterostructure was fabricated through metal-assisted etching and hydrothermal reaction. The metal-assisted etching creates spatial channels that facilitate rapid ion and electron transport.

Measuring Solvation Interactions of Deep Eutectic Solvents Formed by Metal Chlorides and an Imidazolium Salt by Inverse Gas Chromatography.

Deep eutectic solvents (DESs) represent a class of solvents that offer a number of advantages including minimal toxicity, affordability, low vapor pressure, and simple, environmentally friendly preparation methods. They have found utility in areas, such as gas absorption, metal plating, and extractions. However, the relationship between their solvation properties and chemical composition remains poorly understood.

Enzyme-Activated Biosensor Assisted by Enzymatic Rolling Circle Amplification for Sensitive Detection of APE1 and Imaging in Vivo.

Precise identification of tumors is crucial for early diagnosis and treatment of cancer. However, spatially specific and sensitive molecular imaging of tumors remains a challenge due to issues such as low biomarker content and extra-tumor signal leakage. Endogenous purine/pyrimidine endonuclease 1 (APE1) is a marker for tumor diagnosis by detecting activity change and translocation from the nucleus into the cytoplasm.

Research progress on stiffness controllable scaffolds based on gelatin methacryloyl hydrogels for tissue repair and reconstruction.

The extracellular matrix (ECM) maintains tissue morphology and regulates cellular behavior through its network of biochemical components and biophysical signals. Matrix stiffness, as a key physical parameter in cell-matrix interactions, has attracted widespread attention and has been recognized as a crucial regulator of cellular behavior. Tissue engineering mimics the biomechanical environment of the ECM to promote the repair of damaged tissues.

Extract of G. Don, a Medicinal Plant, Ameliorates Myocardial Ischemia-Reperfusion Injury by Inhibiting Platelet Activation.

G. Don is valued for its edible and medicinal qualities. It has been reported that has the potential to inhibit platelet activation, but its mechanism of action is unknown, which needs to be further explored.

Accuracy of eight intraocular lens power calculation formulas in patients with ciliary sulcus implantation.

Purpose: To evaluate the accuracy of intraocular lens (IOL) power calculation for ciliary sulcus-implanted IOL.

Methods: Patients with IOL (Tecnis ZA9003) implanted in the ciliary sulcus were reviewed from March 1, 2021 to November 1, 2024 at Zhongshan Ophthalmic Center, Guangzhou, China. Optic capture was used at all case.

CuOTeDsP nanotherapeutics enhance cuproptosis-mediated immunotherapy by modulating cholesterol metabolism in bladder cancer.

Unlabelled: Elevated squalene epoxidase (SQLE) levels in bladder cancer cells drive abnormal cholesterol accumulation, contributing to malignancy, invasion, and resistance to immunotherapy. Here, we introduce a hollow CuO nanoparticle-based nanotherapeutic, termed CuOTeDsP, which is PEGylated and co-loaded with SQLE inhibitor terbinafine and disulfiram, for enhanced bladder cancer therapy through cholesterol metabolism modulation. CuO nanoparticles exhibit peroxidase-, catalase-, and glutathione oxidase-like enzymatic activities, along with biodegradability, resulting in elevated oxidative stress, alleviation of hypoxia, and responsive therapeutic release.

Aging influences protein digestion, absorption and amino acid metabolism.

Proteins are essential biomolecules that play indispensable roles in maintaining cellular homeostasis and regulating systemic metabolic processes. Protein deficiency is closely associated with age-related chronic diseases. Our purpose is to reveal the reason of protein deficiency in the elderly and potential treatments.

Bismuth-Doped Crystalline/Amorphous WO Composite Film: Superior Electrochromic Performance and Structure Evolution.

Tungsten trioxide (WO) exhibits exceptional electrochromic properties, positioning it as a promising material for the fabrication of high-performance smart glass devices. Here, a two-step sol-gel approach was employed to synthesize crystalline/amorphous bismuth-doped WO (Bi-WO) nanoparticle composite films. The rationally designed composite film demonstrates superior electrochromic performance, featuring a high optical modulation of 82.

Association between ambient air pollution and cardiovascular disease mortality: An individual-level case-crossover study in Hefei, China.

Background: Short-term exposure to air pollution is strongly associated to cardiovascular disease (CVD) mortality; however, detailed studies in rapidly urbanizing areas remain limited. This study aimed to examine short-term associations between ambient air pollutants and CVD mortality using individual-level data in Hefei City.

Methods: We conducted a case-crossover analysis involving 75,230 CVD deaths from 2017 to 2020 in Hefei, China.

Liver ERα mediates sex differences in metabolic pattern changes in response to time-restricted feeding.

Time-restricted feeding (TRF) is a dietary strategy used to prevent and treat obesity in both sexes. However, TRF affects liver metabolism differently in males and females, and the mechanisms behind these differences remain unclear. Our study reveals that during TRF, female livers are more likely to break down amino acids (AAs) to synthesize fats, while male livers significantly reduce fatty acid synthesis.

Effectiveness of pay it forward intervention compared to free and user-paid vaccinations on seasonal influenza vaccination among older adults across seven cities in China: study protocol of a three-arm cluster randomized controlled trial.

Background: Seasonal influenza poses an enormous burden worldwide, with older adults facing preventable morbidity and mortality. However, seasonal influenza vaccination coverage is poor among older populations in China. Pay-it-forward (giving a person a free vaccine and an opportunity to donate to support others) and financial incentives (e.

Vesicular Stomatitis Virus Glycoprotein- and Lentiviral RNA-Based Robust Approach for Rapid and Accurate Quantification of Viable Lentiviral Vectors.

Chimeric antigen receptor (CAR)-T cell (CAR-T) therapy is often used for treating malignant tumors, including leukemia and lymphoma. Lentiviral vectors (LVs) and their dosages are the key determinants of efficient and stable CAR-T cell preparation, cell quality, and treatment costs. However, the rapid quantification of viable LVs remains challenging because of difficulties in determining LV's viability.