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http://dx.doi.org/10.1021/acs.biomac.5c01318 | DOI Listing |
Biomacromolecules
August 2025
Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong 250100, China.
Due to the limited functional groups on poly(ethylene glycol) (PEG) terminals, hydrogels are usually prepared by PEG chains with multiple arms. It is challenging for the preparation of hydrogels using linear PEG. Herein, we report the light-triggered synthesis of hydrogels composed of linear PEG with bis-maleimide groups.
View Article and Find Full Text PDFInt J Mol Sci
September 2023
Institute of Physiology & Department of Biomedical Research (DBMR), Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, 3012 Bern, Switzerland.
Loss of photoreceptors in retinal degenerative diseases also impacts the inner retina: bipolar cell dendrites retract, neurons rewire, and protein expression changes. ON-bipolar cells (OBCs) represent an attractive target for optogenetic vision restoration. However, the above-described maladaptations may negatively impact the quality of restored vision.
View Article and Find Full Text PDFRSC Adv
October 2020
Royal Society of Chemistry Thomas Graham House, Science Park, Milton Road Cambridge CB4 0WF UK
[This retracts the article DOI: 10.1039/C4RA03034F.].
View Article and Find Full Text PDFJ Am Chem Soc
February 2020
State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering , Nanjing Tech University, Nanjing 210009 , China.
Photolabile groups offer promising tools to study biological processes with high spatial and temporal control. In the investigation, we designed and prepared several new glycine amide derivatives of Sanger's reagent and demonstrated that they serve as a new class of photocages for Zn and an acetylcholinesterase (AChE) inhibitor. We showed that the mechanism for photocleavage of these substances involves initial light-driven cyclization between the 2,4-dinitrophenyl and glycine methylene groups to form acyl benzimidazole -oxides, which undergo secondary photoinduced decarboxylation in association with rupture of an amide bond.
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