Foix-Chavany-Marie syndrome: A rare presentation with arachnoid cyst involvement.

Foix-Chavany-Marie syndrome, also known as opercular syndrome, is a rare neurological condition typically caused by bilateral lesions of the opercular cortex. Involvement of arachnoid cysts in the pathogenesis is extremely uncommon. We report the case of a 66-year-old male who presented with sudden-onset dysarthria, dysphagia, and bilateral lower facial paralysis, but retained the ability to yawn and smile, demonstrating the characteristic dissociation between voluntary and involuntary orofacial movements.

Asiaticoside Mitigates Chronic Obstructive Pulmonary Disease by Modulating TRIM27 Stability and Activating PGC-1α/Nrf2 Signaling.

Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease and is pathologically associated with epithelial-mesenchymal transition (EMT) and mitochondrial dysfunction. Asiaticoside (AS) has shown significant anti-inflammatory effects in a variety of diseases. Herein, the pharmacological influences of AS in COPD were probed.

Optimizing a Nurse-Led Receptive Music Therapy (FEMT) Process to Improve Depression Symptoms Among Individuals With a History of Stroke: The Development of an Evidence-Based Complex Intervention Using the MRC Framework.

Chinese traditional five-element music therapy (FEMT), a receptive music therapy, has remarkable effect in intervening depression symptoms among individuals with a history of stroke, yet its content for depression is often unclear. We aim to construct an evidence-based complex intervention by MRC Framework. We first established 10-person program.

Study of the acquisition, replication and transmission of rice stripe virus in vector and non-vector planthoppers based on hemocoel-microinjection.

Background: Rice stripe virus (RSV) naturally infects rice plants through its insect vector during feeding. The small brown planthopper (SBPH) serves as the primary vector to transmit the viruses. The physical barriers preventing virus transmission in non-vectors have remained largely unexplored.

O-GalNAc Glycosylation Activates MBL-Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis.

Liver metastasis is prevalent among patients with neuroendocrine prostate cancer (NEPC) and other types of neuroendocrine (NE) cancers, featuring with an aggressive clinical course and a dismal prognosis. However, the cellular and molecular mechanisms underlying liver-specific metastatic tropism in NE cancers remain poorly understood. Intriguingly, it is found that NEPC liver metastatic foci are frequently associated with thrombi.

Influencing factors of the implementation of mechanical restraint in open psychiatric ward: a retrospective study (2016-2021).

Background: Mechanical restraint, a widely utilized yet contentious restrictive intervention in psychiatric practice, adversely affects both physical and psychological well-being of patients. Understanding the determinants associated with its implementation is crucial for reducing its clinical application. Current studies have primarily evaluated factors influencing mechanical restraint use and related organizational adaptations, but these investigations are limited to short-term observations.

Awareness, needs, and preferences for managing tube feeding resources from hospital to home: a survey among family caregivers.

Background And Objectives: Globally, there is an increasing trend in the number of individuals utilizing home enteral nutrition (HEN). In China, HEN is currently at a nascent stage. We aim to investigate the current situation of home enteral tube feeding (HETF) caregivers to provide more convenient services and assistance to them in China.

The clinical application value and the imaging characteristic of F-FDG PET/CT in tuberculous pericarditis.

Background: Tuberculous pericarditis is the most common cause of pericardial disease in tuberculosis-endemic areas. Accurate and early diagnosis of tuberculous pericarditis is crucial due to its high mortality; however, the diagnostic accuracy of current methods remains suboptimal. This study aims to investigate the clinical application value and imaging characteristics of F-FDG PET/CT in tuberculous pericarditis.

Simultaneous Elucidation of the Chemodiversity of Dissolved Organic Matter and Quantitation of Trace Organic Contaminant Sucralose by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.

Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) has become a cutting-edge technique for molecular characterization of dissolved organic matter (DOM) and trace organic contaminants. Nevertheless, FT-ICR MS is rarely applied to simultaneously elucidate DOM chemodiversity and quantify the concentrations of trace organic contaminants. Compared to conventional solid-phase extraction (SPE), pH-dependent fractionation of DOM molecules using a sequential SPE strategy significantly enhanced the recovery of dissolved organic carbon and yielded more chemical formulas for DOM from environmental samples ( < 0.

Inhibition of histone acetyltransferase KAT8 inhibits oxidative stress and NLRP3 inflammasome activation through reducing p53 acetylation in LPS-induced acute lung injury.

Objective: Acute lung injury (ALI) remains a life-threatening condition characterized by excessive inflammation and oxidative stress. This study aimed to investigate the role of Lysine acetyltransferase 8 (KAT8) in lipopolysaccharide (LPS)-induced ALI and explore its underlying molecular mechanisms.

Methods: Gene and protein expression were analyzed via RT-qPCR and Western blot.

Does rearing host alter host stage preference? Implications for mass rearing of two common pupal parasitoids of Drosophila suzukii.

Pachycrepoideus vindemiae Rondani (Hymenoptera: Pteromalidae) and Trichopria drosophilae (Perkins) (Hymenoptera: Diapriidae) are pupal parasitoids capable of successfully developing on Drosophilidae species, including the invasive pest Drosophila suzukii (Matsumura) (Diptera: Drosophilidae). Both parasitoids are considered potential biological control agents for managing D. suzukii.

Still a Long Way to Go, the Potential of ChatGPT in Personalized Dietary Prescription, From a Perspective of a Clinical Dietitian.

Objective: Prominent large language models, such as OpenAI's Chat Generative Pre-trained Transformer (ChatGPT), have shown promising implementation in the field of nutrition. Special care should be taken when using ChatGPT to prescribe protein-restricted diets for kidney-impaired patients. The objective of the current study is to simulate a chronic kidney disease (CKD) patient and evaluate the capabilities of ChatGPT in the context of dietary prescription, with a focus on protein contents of the diet.

A novel spider toxin as a selective antagonist of the Kv1 subfamily of voltage-gated potassium channels through gating modulation.

Members of the voltage-gated potassium channel subfamily (Kv1) are essential for the nervous and immune systems, necessitating novel modulators and deeper insights into their structure-function relationships. While all known peptide inhibitors targeting Kv1 channels are pore blockers, we identified MrVIII (κ-HxTx-MrVIII), a novel peptide toxin from the venom of spider Macrothele raveni, as the first voltage-gating modifier antagonist with selective activity against Kv1 channels. MrVIII exhibits high-affinity inhibition of Kv1.

Integration of generalized additive models and hyperspectral imaging for quality prediction in Chaoshan beef meatballs: A comprehensive "raw materials-processing-quality-sensory" model.

Maintaining consistent quality of Chaoshan beef meatballs (CBMs) is challenging due to the intricate production processes and stringent raw material requirements, with no effective method currently available for real-time monitoring during production. In this study, a comprehensive "raw materials-processing-quality-sensory" network model to predict CBMs quality attributes by integrating generalized additive model (GAM) with (HSI) was developed. GAM showed strong predictive performance for key attributes such as the pH (R = 0.

Telemedicine in home enteral nutrition: a structured survey exploring acceptability, preferences and experiences among patients.

Background: Given that Telemedicine are widespread in China, and we have developed home enteral nutrition service with telemedicine (HENST) to satisfy HEN requirement of patients. However, only little is known about patient's experience of HENST model. The objective of this interview study was to explore patient's experiences and improvement direction of the HENST model.

Social contact patterns and their impact on the transmission of respiratory pathogens in rural China.

Introduction: Social contact patterns significantly influence the transmission dynamics of respiratory pathogens. Previous surveys have quantified human social contact patterns, yielding heterogeneous results across different locations. However, significant gaps remain in understanding social contact patterns in rural areas of China.

Injectable supramolecular hydrogel co-loading abemaciclib/NLG919 for neoadjuvant immunotherapy of triple-negative breast cancer.

The efficacy of cancer immunotherapy relies on a sufficient amount of functional immune cells. Triple-negative breast cancer lacks enough immune cell infiltration, and adjuvant therapy is necessary to prime anti-tumor immunity. However, the improvement in efficacy is unsatisfactory with concern about inducing systemic immunotoxicity.

Simultaneous monitoring of two comprehensive quality evaluation indexes of frozen-thawed beef meatballs using hyperspectral imaging and multi-task convolutional neural network.

The quality of beef meatballs during repeated freeze-thaw (F-T) cycles was assessed by multiple indicators. This study introduced a novel quality evaluation method using hyperspectral imaging (HSI) and multi-task learning. Seventeen quality indicators were analyzed to assess the impact of F-T cycles.

Serum exosomal small nucleolar RNA (snoRNA) signatures as a predictive biomarker for benign and malignant pulmonary nodules.

Low-dose CT (LDCT) is increasingly recognized as the preferred method for detecting pulmonary nodules. However, distinguishing whether a nodule is benign or malignant often necessitates repeated scans or invasive tissue sampling procedures. Therefore, there is a pressing need for non-invasive techniques to minimize unnecessary interventions.

Identification of candidate single-nucleotide polymorphisms (SNPs) and genes associated with sugarcane leaf scald disease.

Leaf scald, caused by Xanthomonas albilineans, is a severe disease affecting sugarcane worldwide. One of the most practical ways to control it is by developing resistant sugarcane cultivars. It is essential to identify genes associated with the response to leaf scald.

Muscle density, but not size, is independently associated with cognitive health in older adults with hip fractures.

Emerging evidence indicates a complex interplay between skeletal muscle and cognitive function. Despite the known differences between muscle quantity and quality, which can be measured via computed tomography (CT), the precise nature of their associations with cognitive performance remain underexplored. To investigate the links between muscle size and density and cognitive impairment (CI) in the older adults with hip fractures, we conducted a post hoc, cross-sectional analysis within a prospective cohort study on 679 patients with hip fractures over 65.