CO Adsorbates Induced Framework-Associated Low-Valence Co Sites in Co-ZSM-5 for Ethane Dehydrogenation.

The dynamic structural evolution of heterogeneous catalysts is a ubiquitous phenomenon that has attracted a lot of interest. Catalyst reconstruction can occur after appropriate pretreatment, resulting in more efficient active catalysts, which is an attractive but challenging issue. Here, we reveal a CO activation strategy that controls the microenvironment of the Co sites in the high-silica Co-ZSM-5 catalyst (denoted as 0.

GSH-responsive magnetic imaging for monitoring of tumor chemodynamic therapy.

Chemodynamic therapy (CDT) is a promising treatment modality that utilizes highly toxic hydroxyl radicals (˙OH) to kill tumor cells . However, real-time monitoring of drug distribution and therapeutic response remains a challenge, hindering the optimization of personalized treatment regimens. Here, we developed a glutathione (GSH)-responsive nanoreactor (FA-Mn NR), with integrated magnetic resonance imaging (MRI) functionality for self-enhanced CDT.

Association between the Chinese Dietary Inflammatory Index and risk of gastric cancer: a case-control study in Southeastern China.

Objective: This study aimed to investigate the association between the Chinese Dietary Inflammatory Index (CHINA-DII) and the risk of gastric cancer (GC) among adults in Fujian Province of China.

Methods: A 1:1 matched case-control study was conducted between July 2023 and November 2024. A total of 336 newly diagnosed GC cases were recruited from the Union Hospital, and 336 sex-matched healthy controls were enrolled from communities in Fujian Province.

Addressing male HPV vaccination in China: A narrative review of challenges and opportunities.

Human papillomavirus (HPV) poses significant health risks to men, including genital warts and HPV-related cancers. In China, the recent approval of HPV vaccination for males aged 9-26 marks an important step toward gender-inclusive prevention. However, challenges remain in promoting vaccine acceptance among men due to the perception of HPV as a "women's disease," limited public awareness, cultural stigma, and low perceived susceptibility, particularly among heterosexual men.

Sample pretreatment-free rapid determination of difenoconazole in vegetables by swellable hydrogel microneedles.

Difenoconazole is a broad-spectrum triazole fungicide that widely used in fruits and vegetables. However, excessive use of difenoconazole may cause extremely adverse side effects on ecosystems and human health. Nevertheless, currently available detection methods require time-consuming, labor-intensive sample preparation, hindering the rapid screening of difenoconazole in agricultural products.

Subjective socioeconomic status moderates depression's impact on fairness perception in the ultimatum game: A moderated mediation model.

Individuals with depression often exhibit cognitive distortions in socioeconomic decision-making, particularly in interpreting fairness. However, the role of subjective socioeconomic status in shaping these distortions remains underexplored. This study investigates how depression influences fairness perception and rejection behavior in the Ultimatum Game.

Quantitative decoding of coupled carbon and energy metabolism in Pseudomonas putida for lignin carbon utilization.

Soil Pseudomonas species, which thrive on lignin derivatives, are widely explored for biotechnology applications in lignin valorization. However, how the native metabolism coordinates phenolic carbon processing with required cofactor generation remains poorly understood. Here, we achieve quantitative understanding of this metabolic balance through a detailed multi-omics investigation of Pseudomonas putida KT2440 grown on four common phenolic acid substrates: ferulate, p-coumarate, vanillate, and 4-hydroxybenzoate.

Robust Singlet Fission in Disordered Thin Films of a Tethered Dipyrrolonaphthyridinedione Cyclophane-Like Skeleton.

The practical applications of singlet fission (SF) are currently restricted by the limited number of SF-active materials and the stringent requirement of intermolecular interactions. It is still imperative but challenging work to develop an efficient SF system weakly dependent on molecular orientation and film morphology. Here, we elaborately designed a tethered cyclophane-like skeleton and constructed a disordered aggregation system.

Genomic Insights into the Molecular Basis of Broad Host Adaptability of the Entomopathogenic Fungus (Entomophthoromycotina).

(Entomophthorales), a fungal pathogen with a broad insect host range, is a promising candidate for biocontrol applications. We sequenced a strain isolated from a sp. cadaver using PacBio long-read sequencing to elucidate the molecular basis of its wide host adaptability.

YOLO-GL for efficient multi-target detection in large FOV via hierarchical feature fusion.

In modern industrial construction sites, safety inspection tasks face challenges such as large-scale variations and complex multi-object detection scenarios, particularly in detecting critical safety indicators like flames, smoke, personnel attire, and operational behaviors. To address these limitations, this paper proposes YOLO-GL, an enhanced detection network featuring three key innovations: (1) a redesigned Parallelized Local-Global Multi-Level Fusion Module (C2f_gl) with a local-global attention mechanism for improved multi-scale feature representation; (2) a hierarchical feature fusion architecture; and (3) an adaptive feature fusion shuffling module (Multi-Scale Fusion Module and Adaptive Channel Shuffling Module, MSF&ACS) for dynamic optimization of cross-scale semantic relationships. Extensive experiments on composite datasets combining public benchmarks and industrial site collections demonstrate that YOLO-GL achieves state-of-the-art performance, improving mAP@0.

Interfacial Charge Separation Engineering Enables Dual Small-Molecule Probe-Based Photoelectrochemical Multi-Enzyme Sensing.

Photoelectrochemical (PEC) biosensors remain constrained in multianalyte detection due to inefficient charge separation and signal crosstalk. To address these challenges, we developed a dual small-molecule probe-modulated charge separation system by integrating coumarin 6 (C6) and a silane probe (SP) into a titanium-based metal organic framework (Ti MOF). The porous crystalline structure and favorable electron transport properties of the Ti MOF enable efficient interfacial electron redistribution between the molecular probes and the MOF scaffold.

Computational discovery and repurposing of chloramphenicol succinate as a potent P2Y receptor antagonist for inflammatory bowel disease therapy.

Introduction: The P2Y receptor (P2YR), a Gi-coupled receptor activated by UDP-glucose, plays a critical role in inflammatory responses and immune regulation. Existing P2YR antagonists face limitations such as poor bioavailability and structural homogeneity, hindering therapeutic development for inflammatory bowel disease (IBD). Drug repurposing offers a promising strategy to bypass traditional drug discovery challenges by leveraging approved drugs with established safety profiles.

Variations in the lipid of dry-cured mutton ham during storage: UPLC-MS-MS-based lipidomic analysis.

Dry-cured mutton ham is prone to quality deterioration during storage due to excessive lipid oxidation. Therefore, to control the ham quality, it is essential to comprehensively understand the lipid changes occurring in the storage. In this study, the variations and primary metabolic pathways of ham lipids during storage were investigated utilizing the lipid metabolomics.

Constructing Amine-Functionalized Hierarchically Porous Porphyrin-Based Metal-Organic Frameworks for Highly Enhanced Direct Air Capture of CO.

Direct air capture (DAC) of carbon dioxide (CO) has emerged as a prominent negative carbon emission technology for mitigating the greenhouse effect. Among various adsorbents, amine-functionalized metal-organic frameworks (MOFs) have shown exciting potential as adsorbents for atmospheric CO capture. However, the intrinsic microporosity of many MOFs restricts amine loading and uniform dispersion, diminishing the CO adsorption efficiency.

Integrating flavonoid metabolome and RNA-seq data unveil flower color variation in Bombax ceiba.

Floral pigmentation is essential for ornamental species. This investigation utilized flower tissues from five distinct color phenotypes (dark red, red, orange-red, orange-yellow, yellow) of Bombax ceiba to conduct targeted flavonoid metabolomics and RNA sequencing analyses, resulting in the identification of 137 metabolites and 44,725 genes. The results indicated that the expression levels of BcCHSs, BcCHIs, BcF3'5'Hs, BcDFRs, and BcLDOXs were significantly lower in yellow flowers compared to their counterparts of other colors.

Targeting the MYC oncogene with a selective bi-steric mTORC1 inhibitor elicits tumor regression in MYC-driven cancers.

The MYC oncogene is causally involved in the pathogenesis of most human cancers. The mTORC1 complex regulates MYC translation through 4EBP1 and S6K. However, agents that selectively target mTORC1 (without affecting mTORC2) have so far failed to reactivate 4EBP1 and, thus, cannot effectively suppress MYC in vivo.

Compensation of the transverse chromatic aberration in a color-coded fringe projection profilometry.

Color-coded fringe projection profilometry (FPP) is one of the most important single-frame three-dimensional (3D) shape measurement techniques. Transverse chromatic aberration (TCA) in a color-coded FPP system yields imaging deviations, which will result in 3D shape measurement error. In this work, a TCA compensation method for color-coded FPP is proposed.

Comparative Effects of Two Acupuncture Protocols in the Management of Chronic Insomnia: A Randomized Controlled Trial.

Background: Chronic Insomnia Disorder (CID) significantly impairs both sleep quality and daytime functioning. However, current treatments have limited efficacy in improving daytime function and are often associated with side effects. This highlights the urgent need for effective and safe therapeutic approaches that can target both nocturnal and daytime symptoms.

Effect of job insecurity on anxiety among university young teachers: Chain mediating roles of perceived stress and insomnia.

Objectives: Anxiety is a common negative emotion. Under current social circumstances, university young teachers face multiple stressors and are more prone to anxiety, seriously threatening their physical and mental health. This study aims to investigate the impact of job insecurity on anxiety of university young teachers, while exploring the mediating roles of perceived stress and insomnia on this relationship.

Redefining AT1 Receptor PET Imaging: Introducing the Radiotracer [F]DR29.

Background: AT1R (angiotensin II type 1 receptors) are central to the renin-angiotensin system and are involved in regulating blood pressure and renal physiology. This study introduces [F]DR29, a fluorine-18-labeled radiotracer for positron emission tomography imaging, to enable noninvasive visualization of AT1R expression. Its potential applications in understanding AT1R-associated renal processes are explored in healthy and hypertensive rat models.

 (Balsaminaceae), a new species from Sichuan, China.

K.Huang & Z.X.

Visible Light-Driven Soft Actuator Exhibiting Multistage Shape Morphing.

Traditional soft robots, while praised for their flexibility and biocompatibility, often face challenges with complex motion and adaptability. In this work, a visible light-driven liquid crystalline network (LCN) film with a multistage photo-responsive behavior is judiciously designed and prepared. By integrating donor-acceptor stenhouse adducts (DASAs) into LCN matrix, it is found that the DASA exhibits polymerization temperature-dependent isomerization, indicating an opportunity to fabricate complex photo-driven soft actuators and devices by simply adjusting the polymerization conditions.

Ce Single Atom-Engineered Amorphous/Crystalline Nanosheets for Enhanced Alkaline Water Electrolysis.

Designing nanocatalysts with fast water dissociation kinetics is key to achieving the industrial current density of the cathodic hydrogen evolution reaction (HER) for green hydrogen production via water electrolysis, which remains a grand challenge. Here, leverage single-atom engineering,a Ce single-atom-doped amorphous RuO nanosheet featuring abundant amorphous/crystalline nanojunctions, namely, ac-CeRuO is successfully developed. When employed as a catalyst for alkaline HER, the ac-CeRuO catalyst displays an overpotential of only 8.

Nurses' Perceptions and Experiences of Unethical Pro-Organizational Behavior: A Descriptive Qualitative Study.

Unethical pro-organizational behavior (UPB) is detrimental to the organization's long-term growth and can even affect the health of the industry landscape. However, we know very little about the current UPB in nursing. This study aimed to explore nurses' perceptions and experiences of UPB using the theory of planned behavior (TPB).

Seismic retrofit of high-rise buildings using buckling-restrained braces: design methodology and performance evaluation.

This study proposes a comprehensive seismic retrofit strategy for a 24-story steel building originally designed according to the outdated seismic code (GB 50011-2001). The building suffers from structural deficiencies, including excessive torsional displacement, insufficient axial load-bearing capacity of columns, and the presence of weak-story mechanisms. In this retrofit, BRB were adopted to make the structure comply with the modern seismic code (GB 50011-2010).