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Background: Mechanical restraint, a widely utilized yet contentious restrictive intervention in psychiatric practice, adversely affects both physical and psychological well-being of patients. Understanding the determinants associated with its implementation is crucial for reducing its clinical application. Current studies have primarily evaluated factors influencing mechanical restraint use and related organizational adaptations, but these investigations are limited to short-term observations. Furthermore, research examining correlates in patients subjected to recurrent mechanical restraint episodes in open psychiatric wards remains scarce, with biological contributing factors particularly lacking empirical evidence.
Objective: This study aimed to analyze differences between inpatients experiencing single versus multiple restraint episodes in the open psychiatric ward setting and identify factors associated with multiple restraint occurrences.
Methods: This study is a retrospective analysis of electronic health record data from patients who underwent mechanical restraint in the open psychiatric ward of a Class III Grade A general hospital in China between 2016 and 2021. The data encompassed sociodemographic information, clinical characteristics, and biological indicators.
Results: The study included a total of 449 patients who underwent mechanical restraint during hospitalization. Of these, 63.5% experienced a single episode of restraint, while 36.5% experienced multiple episodes. Furthermore, compared to patients with a single episode of mechanical restraint, those with multiple episodes exhibited a significantly earlier timing of the first restraint (p = 0.011), a prolonged hospital stay (p = 0.044), and relatively higher creatine kinase levels (p = 0.008). Multivariate analysis identified the timing of restraint (OR: 0.947, p = 0.005) and the duration of hospitalization (OR: 1.034, p = 0.003) as significant predictors of multiple restraint episodes.
Conclusion: Among psychiatric inpatients in open wards, those subjected to multiple restraints exhibited earlier occurrence of the first restraint after admission, prolonged hospital stays, and relatively higher serum creatine kinase levels at admission. These findings suggest that in clinical practice, repeated restraint may potentially prolong hospitalization duration. Monitoring serum creatine kinase levels at admission may aid in identifying patients at risk for repeated restraints. Furthermore, early risk identification and the implementation of alternative interventions are critical to reducing the necessity for restraint interventions.
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http://dx.doi.org/10.1186/s12888-025-06969-z | DOI Listing |
PLoS One
September 2025
Guangxi Transportation Investment Group Co., Ltd., Nanning, Guangxi, China.
To investigate the axial compressive behavior of CFRP-PVC square tube-embedded aluminum concrete columns, five specimens and one control specimen without I-shaped aluminum were tested under uniaxial compression, with the number of CFRP layers and spacing as variable parameters. The failure modes, load-displacement responses, and mechanical properties such as peak load, ductility, stiffness, and energy dissipation were systematically analyzed. Results showed that the incorporation of I-shaped aluminum improved the peak load and ductility by an average of 48.
View Article and Find Full Text PDFBrain Behav
September 2025
Tongde Hospital of Zhejiang Province Affiliated to Zhejiang Chinese Medical University(Tongde Hospital of Zhejiang Province), Hangzhou, China.
Background: Mental disorders frequently co-occur with pain, yet pain mechanisms in non-peripheral etiologies (e.g., chronic psychological stress) remain underexplored.
View Article and Find Full Text PDFIndian J Psychiatry
August 2025
Department of Psychiatry, AIIMS, New Delhi, India.
Background: Coercive interventions may be required during psychiatric in-patient care, but require careful monitoring to minimize inappropriate use.
Aim: In this article, we aimed to systematically review published literature on the frequency and patterns of selected coercive methods in mental health establishments (MHEs) in India.
Methods: From a systematic screening of four databases (MEDLINE, EMBASE, CINAHL and PSYCINFO) supplemented by searching relevant citations and selected journals, we retrieved studies of frequency and patterns of mechanical restraint, chemical restraint and seclusion at Indian MHEs.
Int J Biol Macromol
September 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, PR China. Electronic address:
Due to the poor regeneration ability of cartilage tissue, the design and fabrication of permanent hydrogel cartilage scaffolds with mechanical properties matching is still an urgent challenge. In this study, we propose an "inner swelling-outer restraint" strategy to construct Janus hydrogel for pressure-bearing cartilage replacement, which is inspired by the "Lamina-splendens" structure of cartilage. As a proof of concept, the poly(vinyl alcohol)/carboxymethyl cellulose sodium (PVA/CMCNa) layer is designed to capture more fluid by introducing negatively charged aggregates, while the macromolecular conformation of the PVA/MoS layer can be densified through wet annealing, thereby increasing the liquid permeation resistance of the PVA/CMCNa layer.
View Article and Find Full Text PDFJ Forensic Nurs
September 2025
Forensic Mental Health Research Unit Middelfart (RFM), Department of Regional Health Research, Faculty of Health Science, University of Southern.
Introduction: Most interventions aimed at reducing mechanical restraint (MR) have not been adapted to forensic mental health settings (FMHS) and rarely consider the perspectives of service users (SUs), relatives, and staff.
Aim: To investigate the perceptions of SUs, relatives, and staff regarding the content and feasibility of seven interventions to reduce MR use in adult FMHS.
Methods: We conducted semi-structured, one-on-one, and group interviews with SUs, relatives, and staff within an FMHS and analyzed the data using content analysis.