Assembling chromosome-level genomes of male and female Chanodichthys mongolicus using PacBio HiFi reads and Hi-C technologies.

Chanodichthys mongolicus, a carnivorous fish belonging to the Cyprinidae family (Erythroculter), is widely distributed in reservoirs and lakes across China. However, the lack of research on whole genome assembly has impeded advancements in genetic studies for this species. In this study, we employed PacBio sequencing and Hi-C technology to assemble high-quality genomes for both female and male Chanodichthys mongolicus at the chromosome level.

Association of Vitiligo With Autoimmune Disorders: A Bidirectional Two-Sample and Summary-Based Mendelian Randomization Study.

Background: The existence of a definite direct causal relationship between vitiligo and diverse autoimmune disorders remains unknown due to the influence of confounding factors and potential reverse causality.

Methods: Mendelian randomization (MR) is a technique employed to explore causal connections between two phenotypes. In our research, bidirectional two-sample MR analyses were utilized to evaluate the causal connections between vitiligo and multiple autoimmune diseases (systemic lupus erythematosus, Graves' disease, inflammatory bowel disease, alopecia areata [AA], type 1 diabetes mellitus [T1MD], and rheumatoid arthritis [RA]).

Impacts of Topical Treatments and Phototherapy on Stratum Corneum Hydration, Sebum and Elasticity in Vitiligo Skin.

Introduction: Vitiligo is a prevalent depigmentation disorder. Due to the depigmentation and treatments, skin function of patients with vitiligo may be affected, manifested by changes in the stratum corneum (SC) hydration, sebum and elasticity. However, few researchers have paid attention to the skin condition of vitiligo after treatment.

Bubble Evolution in Rechargeable Zinc-Air Batteries: Mechanisms, Mitigation Strategies, and Future Prospects.

Rechargeable zinc-air batteries (ZABs) are considered among the most promising power sources for portable electronic devices and electric vehicles due to their high energy density, environmental friendliness, and low production costs. However, a major challenge hindering their commercialization is the issue of gas evolution during operation. The electrochemical reactions at both the zinc electrode (hydrogen evolution reaction, HER) and the air electrode (oxygen evolution reaction, OER) result in the formation of gas bubbles.

Electrodissolution-driven enhancement in Zn electrode reversibility.

Current strategies to enhance Zn reversibility in aqueous Zn batteries (AZBs) primarily focus on inducing planar deposition. However, electrodissolution, as the initial operational step in AZBs, significantly affects deposition behavior and reversibility, yet it is surprisingly overlooked. Herein, the crucial electrodissolution behavior of Zn electrodes and its impact on irreversibility are comprehensively elucidated.

Adverse event of ruxolitinib cream: a real-world analysis based on FDA Adverse Event Reporting System from 2021 to 2024.

Background: Ruxolitinib cream, a topical Janus kinase (JAK) inhibitor, is a widely used treatment for various dermatological diseases. This study employs the FDA Adverse Event Reporting System (FAERS) database to examine adverse events (AEs) associated with ruxolitinib cream.

Methods: This study employed disproportionate analysis methods, including reported odds ratio and proportional reporting ratio, to collate AEs reported from the fourth quarter of 2021 to the first quarter of 2024.

The causal relationship between negative emotions and inflammatory dermatoses: a bidirectional Mendelian randomization study.

Purpose: Observational studies have suggested a potential link between emotions and inflammatory dermatoses. However, research on the causal relationship between different types of emotions and inflammatory dermatoses is lacking. This study is aimed to investigate the causal relationship between negative emotions and inflammatory dermatoses through Mendelian randomization (MR) analysis.

Knowledge Structure and Trends of Vitiligo From 2002 to 2023: A Bibliometric Analysis.

Introduction: Vitiligo is a common acquired depigmenting dermatosis resulting from a loss of epidermal melanocytes. The academic attention to vitiligo has gradually increased over the past two decades.

Objective: We aimed to explore the current research structure and trends of vitiligo.

Identification of dietary factors that impact the gut microbiota associated with vitiligo: A Mendelian randomization study and meta-analysis.

Previous observational studies have suggested that gut microbiota might be associated with vitiligo. However, owing to the limitations in observational studies of reverse causality and confounders, it remains unclear that whether and how the causal relationships exist. The results suggested that pylum.

In vivo imaging of vagal-induced myenteric plexus responses in gastrointestinal tract with an optical window.

The vagus nerve (VN) extensively innervates the gastric enteric nervous system (ENS), but its influence on gastric ENS functionality and motility in vivo remains unclear due to technical challenges. Here we describe a method for stable, long-term observation of gastric ENS activity and muscle dynamics at cellular resolution, which can also be extended to intestinal applications. This method involves ENS-specific labeling and the implantation of an abdominal wall window for optical recording in male mice.

Polycyclic aromatic hydrocarbons exposure associated with increased risk of psoriasis.

Psoriasis is considered to be multifactorial, with both genetic and environmental factors contributing to its development. Polycyclic aromatic hydrocarbons (PAHs) are widespread in the environment, originating from sources such as cigarette smoke, exhaust emissions, grilled foods, smoked foods and urban air. Researchs have established a link between PAHs exposure and autoimmune disorders; however, specific effects of PAHs on psoriasis remain underexplored.

Thermodynamically spontaneously intercalated HO enables LiMnO with enhanced proton tolerance in aqueous batteries.

LiMnO (LMO) is an attractive positive electrode material for aqueous lithium-ion batteries (ALIBs), but its inferior cycle performance limits the practical application. The degradation mechanism of LMO in ALIBs is still unclear, resulting in inability to predictably improve its structural stability. The electrode/electrolyte interface is believed to play an important role in electrode degradation.

Identification of candidate single-nucleotide polymorphisms (SNPs) and genes associated with sugarcane leaf scald disease.

Leaf scald, caused by Xanthomonas albilineans, is a severe disease affecting sugarcane worldwide. One of the most practical ways to control it is by developing resistant sugarcane cultivars. It is essential to identify genes associated with the response to leaf scald.

Link Brain-Wide Projectome to Neuronal Dynamics in the Mouse Brain.

Knowledge about the neuronal dynamics and the projectome are both essential for understanding how the neuronal network functions in concert. However, it remains challenging to obtain the neural activity and the brain-wide projectome for the same neurons, especially for neurons in subcortical brain regions. Here, by combining in vivo microscopy and high-definition fluorescence micro-optical sectioning tomography, we have developed strategies for mapping the brain-wide projectome of functionally relevant neurons in the somatosensory cortex, the dorsal hippocampus, and the substantia nigra pars compacta.

Description of a pathogenic strain of Aeromonas dhakensis isolated from Ancherythroculter nigrocauda in an inland region of China.

Aeromonas dhakensis is reported as an emerging pathogenic species within the genus Aeromonas and is widely distributed in tropical coastal areas. This study provided a detailed description and characterization of a strain of A. dhakensis (202108B1) isolated from diseased Ancherythroculter nigrocauda in an inland region of China.

A chromosomal-scale genome assembly of modern cultivated hybrid sugarcane provides insights into origination and evolution.

Sugarcane is a vital crop with significant economic and industrial value. However, the cultivated sugarcane's ultra-complex genome still needs to be resolved due to its high ploidy and extensive recombination between the two subgenomes. Here, we generate a chromosomal-scale, haplotype-resolved genome assembly for a hybrid sugarcane cultivar ZZ1.

One-Step Hydrothermal Synthesis of NVO Cathodes with Varied Lattice NH Content: Effect on Structural Evolution and Electrochemical Performance.

Aqueous zinc ion batteries have been extensively researched due to their distinctive advantages such as low cost and high safety. Vanadium oxides are important cathode materials, however, poor cycle life caused by vanadium dissolution limits their application. Recent studies show that the lattice NH in vanadium oxides can act as a pillar to enhance structural stability and play a crucial role in improving its cycling stability.

Somatic and Germline Variants and Coronary Heart Disease in a Chinese Population.

Importance: The genetic basis of coronary heart disease (CHD) has expanded from a germline to somatic genome, including clonal hematopoiesis of indeterminate potential (CHIP). How CHIP confers CHD risk in East Asian individuals, especially those with small clones (variant allele fraction [VAF] 0.5%-2%) and different genetic backgrounds, was completely unknown.

Egg consumption and risk of coronary artery disease, potential amplification by high genetic susceptibility: a prospective cohort study.

Background: Remarkable heterogeneity has been observed among population-based studies on egg consumption and risk of coronary artery disease (CAD). Whether genetic susceptibility serves as a potential explanation for this inconsistency remains unknown.

Objectives: We performed a prospective cohort study to investigate the association of egg consumption with incident CAD at different genetic susceptibilities.

A high-throughput phenotyping method for sugarcane rind penetrometer resistance and breaking force characterization by near-infrared spectroscopy.

Background: Sugarcane (Saccharum spp.) is the core crop for sugar and bioethanol production over the world. A major problem in sugarcane production is stalk lodging due to weak mechanical strength.

A high-throughput phenotyping assay for precisely determining stalk crushing strength in large-scale sugarcane germplasm.

Sugarcane is a major industrial crop around the world. Lodging due to weak mechanical strength is one of the main problems leading to huge yield losses in sugarcane. However, due to the lack of high efficiency phenotyping methods for stalk mechanical strength characterization, genetic approaches for lodging-resistant improvement are severely restricted.

Two-photon fluorescence imaging using a tunable spectral window based on fiber supercontinuum.

Two-photon excitation fluorescence (TPEF) microscopy has evolved into a versatile tool in biological research. However, the multiplexing capability of TPEF microscopy is limited by the narrow spectral bandwidth of the light source. In this study, we apply a photonic crystal fiber in TPEF microscopy to broaden the excitation source bandwidth.

Prevalence and genetic diversity of isolated from aquaculture systems in the Poyang Lake area, China.

The area around Poyang Lake is the main aquaculture area in Jiangxi Province, China, and an important base for the supply of freshwater aquatic products. Aquaculture in the Poyang Lake area is severely threatened by diseases caused by bacterial pathogens, and has been the main pathogen in recent years. In this paper, ERIC-PCR genotyping, virulence gene and antimicrobial resistance gene detection, and drug susceptibility tests were carried out on 46 isolates obtained from aquaculture systems in the Poyang Lake area from 2016 to 2020.

Stabilizing Layered Structure in Aqueous Electrolyte via O2-Type Oxygen Stacking.

Despite the high energy density of O3-type layered cathode materials, the short cycle life in aqueous electrolyte hinders their practical applications in aqueous lithium-ion batteries (ALIBs). In this work, it is demonstrated that the structural stability of layered LiCoO in aqueous electrolyte can be remarkably improved by altering the oxygen stacking from O3 to O2. As compared to the O3-type LiCoO , the O2-type LiCoO exhibits significantly improved cycle performance in neutral aqueous electrolyte.

Stabilizing Layered Structure in Aqueous Electrolyte via Dynamic Water Intercalation/Deintercalation.

Aqueous lithium-ion batteries (ALIBs) with nonflammable feature attract great attention for large-scale energy storage. However, the layered cathode materials (such as LiCoO ) present serious capacity decay in ALIBs. The degradation mechanism of layered cathode materials in ALIBs is still not clear and an effective strategy to improve cycling stability remains a great challenge.