Implementation of HL7 FHIR-Based Terminology Services for a National Federated Health Research Infrastructure.

Introduction: As part of the German Medical Informatics Initiative (MII) and Network University Medicine (NUM), a central research terminology service (TS) is provided by the Service Unit Terminology Services (SU-TermServ). This HL7 FHIR-based service depends on the timely and comprehensive availability of FHIR terminology resources to provide the necessary interactions for the distributed MII/NUM infrastructure. While German legislation has recently instituted a national terminology service for medical classifications and terminologies, the scope of the MII and NUM extends beyond routine patient care, encompassing the need for supplementary or specialized services and terminologies that are not commonly utilized elsewhere.

Tribology of EDM Recast Layers Vis-À-Vis TIG Cladding Coatings: An Experimental Investigation.

Tribological performance is critical for the longevity and efficiency of machined components in industries such as aerospace, automotive, and biomedical. This study investigates whether electrical discharge machining recast layers can serve as a cost-effective and time-efficient alternative to conventional tungsten inert gas cladding coatings for enhancing surface properties. The samples were prepared using electrical discharge machining and tungsten inert gas cladding.

Modulation of Third-Order Nonlinear Optical Response in Copper-Induced Gold Nanoclusters.

Nonlinear optical (NLO) materials play a pivotal role in controlling laser characteristics, including phase and frequency, making them essential for optoelectronic applications. This study presents a quantum chemical investigation into the effects of copper doping on the NLO properties of small gold clusters. Using density functional theory with the CAM-B3LYP/LanL2DZ level of theory, we examined both pure (Au, where 8 ≤ ≤ 10) and copper-doped (AuCu) gold clusters.

MatriDerm Dermal Substitute as an Adjunct in Primary Cleft Palate Repair for the Closure of Lateral Palatal Gaps: A Pilot Study.

This pilot study evaluates the effectiveness of MatriDerm (MedSkin Solutions Dr. Suwelack AG) as a dermal substitute in primary cleft palate surgery, especially for closure of lateral palatal gaps. The authors retrospectively studied 20 patients (mean age: 10 mo) who underwent unilateral or bilateral cleft palate repair at Al Jalila Children's Specialty Hospital from January 2022 to December 2024.

Sustainable concrete production through the integration of waste foundry sand, fly ash, silica fume and metakaolin.

This exploratory study investigates the use of waste foundry sand (WFS), combined with supplement cementitious materials (SCMs), in concrete production. The Preliminary Investigation is based on three groups, where the first group studies different percentages of natural sand replacement with WFS (i.e.

Global Environmental Geochemistry and Molecular Speciation of Heavy Metals in Soils and Groundwater from Abandoned Smelting Sites: Analysis of the Contamination Dynamics and Remediation Alternatives in Karst Settings.

Abandoned smelting sites in karst terrain pose a serious environmental problem due to the complex relationship between specific hydrogeological elements and heavy metal contamination. This review combines work from across the globe to consider how karst-specific features (i.e.

Enhanced Encoding Module of AisNet with Charge Features: An Application to the S2 Data Set.

This research introduces a charge-enhanced encoding module within the AisNet multifeature fusion framework, demonstrating superior force error accuracy and cross-model transferability, and achieving in state-of-the-art performance on the S2 dataset. Compared with the original AisNet, the addition of the Coulomb matrix enables AisNet-C with ternary features to maintain its leading performance in all feature dimensions. Through t-SNE and PCA analysis, long-range Coulomb interaction effectively enhances global environmental resolution, forming a synergistic relationship with other features.

Study on the effect of alginate coated Ca-Fe bimetallic composite biochar microspheres on the removal of short-chain PFAS.

The remediation of short-chain per- and poly-fluoroalkyl substances (PFAS) contamination is challenging, and the low adsorption capacity and slow adsorption kinetics of conventional adsorbents for short-chain PFAS inhibit their application. In this study, alginate coated Ca-Fe bimetallic biochar balls (CA/Ca-Fe/BC) were prepared using pomelo peel and corn stover as biochar materials. The removal of short-chain PFAS involves two key processes: adsorption and degradation, and the removal efficiency is better than that of existing adsorption materials.

Phytoremediation potential of native medicinal plant species in mining degraded soil of Mohmand Northwest Pakistan.

The phytoremediation efficiency of sixteen native medicinal plants was studied in soil degraded by mining in Mohmand, Northwest Pakistan. Elemental analyses of samples were carried out by using an atomic absorption spectrophotometer. The average values of soil pH (7.

Selection of reference genes in Thermothelomyces fergusii: insights from genomic and expression analysis in response to different carbon sources.

Background: RNA expression analysis using reverse transcription qPCR requires reference genes for accurate data normalization. However, some reference genes can show significant variability in specific biological samples, raising concerns about the reliability of this method. This study assessed the expression levels of 12 reference genes in Thermothelomyces fergusii during spore and mycelium cultivation under different carbon source media (avicel, cellobiose, and glucose) using RT-qPCR.

Ecological and health risks assessment of potentially toxic elements in edible plants across mining and non-mining areas of Northwest, Pakistan.

The current study evaluated the concentrations, ecological and health risks, and phytoremediation potential of potentially toxic elements (PTEs) in soil and edible plant samples from mining and non-mining areas of District Mohmand, Pakistan. Soil and plant samples were collected, oven-dried, acid-digested (HNO:HCl, 3:1) and analyzed using atomic absorption spectrophotometry (Perkin-Elmer AA400). Traditionally, many of the studied plant species serve both as food and in ethnomedicines.

Machine learning prediction and explainability analysis of high strength glass powder concrete using SHAP PDP and ICE.

Achieving high-strength concrete (HSC) with sustainable supplementary cementitious materials (SCMs) remains a significant challenge in the construction industry. Although glass powder has shown promise as a partial cement substitute, its specific impact on HSC growth is still unclear. This study aims to evaluate the compressive strength (CS) of high strength glass-powder concrete (HSGPC) using machine learning (ML) models and enhance predictive accuracy through hybrid optimization techniques.

Development of cookies from wheat-yellow/white maize composite blends and their physical and sensory evaluation.

Wheat is a staple food in many countries globally, but it alone cannot meet the dietary demands of the growing population. To address this, there is an increasingly critical need to integrate alternative cereals into diets, enhancing nutritional diversity and reducing reliance on imports. In present study, various composite blends of wheat and maize were developed by taking different proportions of maize flour (10, 20, 30 and 40%) into the wheat flour and analyzed for proximate composition, phytates, minerals and pasting properties.

In-depth exploration of software defects and self-admitted technical debt through cutting-edge deep learning techniques.

Most previous research focuses on finding Self-Admitted Technical Debt (SATD) or detecting bugs alone, rather to addressing the concurrent identification of both issues. These study investigations solely identify and classify the SATD or faults, without identifying or categorising bugs based on SATD. Furthermore, the majority of current methodologies do not incorporate contemporary deep learning techniques.

Development and in vitro evaluation of mefenamic acid orodispersible tablets prepared by direct compression.

Mefenamic acid functions as a nonsteroidal anti-inflammatory drug (NSAID) of the fenamate class, which treats pain and inflammation by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes to decrease prostaglandin production. Mefenamic acid has strong therapeutic properties that help to treat arthritis and dysmenorrhea. The rapid dissolution of orodispersible tablets (ODTs) makes them an effective treatment option for patients with dysphagia.

Impact of End-capped Acceptor Modification in Anthanthrone-Based D-π-A Type Donor Materials for Organic and as Hole Transporting Materials for Perovskite Solar Cells.

Efficient hole-transporting materials (HTMs) are important for improving the stability and performance of all-small-molecules organic solar cells (ASM-OSCs) and perovskite solar cells (PSCs). However, low photovoltaic efficiencies, due to challenges in the designing of small molecular electron donors (SMEDs) with ideal energy levels, light absorption, and optoelectronic properties, hinder their widespread usage. This study presents an end-capped molecular engineering strategy to develop highly efficient HTMs for PSCs and donor materials for OSCs.

What's Wrong with Gazanias? A Review of the Biology and Management of Weedy Gazania Species.

is a genus of herbaceous plants from the Asteraceae (daisy) family. Native to southern Africa, several species of this genus have been introduced to different countries as ornamental garden plants due to their beautiful flowers. In the wild, species have been observed with flowers of different shades of pink, red, yellow, orange and combination of these colours.

Deciphering the Role of Rhodanine Flanked Non-Fullerene Acceptor Molecules for Efficient Organic Photovoltaics.

In recent years, extensive research has been conducted with the aim of developing non-fullerene acceptors as they have a promising ability to drive the development of cost-effective and highly efficient organic solar cells (OSCs). By harnessing the potential of rhodanine-flanked non-fullerene acceptors (NFAs), we proposed eight new A-D-A type NFAs (SBA1-SBA8) through precise end-cap modifications on both sides of the bridging-core unit. We performed various advanced quantum chemical analyses to unveil these designed materials' potential and compared them with the synthetic reference molecule (R).

Exploring the impact of pregnancy on cognitive function: a comparative study in a low-income setting.

Background: Cognitive dysfunction is a significant contributor to mental health complexities during pregnancy, potentially leading to heightened rates of pregnancy-related mortality and inadequate prenatal care. However, limited research has been conducted to explore the relationship between pregnancy and cognitive decline, especially in low-income settings such as Pakistan. Therefore, this study aimed to establish a clear link between cognitive function and pregnancy.

Green and Sustainable Electrospun Poly(vinyl alcohol)/Eggshell Nanofiber Membrane with Lemon-Honey for Facial Mask Development.

Facial masks contain additives such as thickeners and preservatives that have adverse effects on the skin, and there is growing demand for organic products. Inspired by this, we developed a poly(vinyl alcohol) (PVA) nanofibrous facial mask that contains all-natural ingredients such as honey and an eggshell membrane (ESM) by a green solvent-based electrospinning technique. Various analyses, including SEM, XRD, FT-IR, and TGA measurements, and tests for water solubility, wettability, water absorption and retention, antioxidant activity, and antibacterial properties were performed.

Efficient Water-Soluble Cu(II) Complex-Immobilized Electrospun Hydrophobic Polycaprolactone Nanofiber Composites for Highly Controlled and Long-Term Release.

Water-soluble Cu complexes offer diverse applications in the biomedical field as Cu is an essential trace element for many physiological functions, including the wound healing process. Controlled delivery of such bioactive Cu complexes to the target system is a promising approach in biomedical applications. Herein, water-soluble Cu(II)-Schiff base complex-incorporated PCL nanofiber composites (PCL@C-1%, PCL@C-3%, and PCL@C-5%) were fabricated by the electrospinning process using a green solvent, acetic acid.